ATE545411T1 - Herstellungsverfahren für feststoffdispersionen - Google Patents
Herstellungsverfahren für feststoffdispersionenInfo
- Publication number
- ATE545411T1 ATE545411T1 AT09725902T AT09725902T ATE545411T1 AT E545411 T1 ATE545411 T1 AT E545411T1 AT 09725902 T AT09725902 T AT 09725902T AT 09725902 T AT09725902 T AT 09725902T AT E545411 T1 ATE545411 T1 AT E545411T1
- Authority
- AT
- Austria
- Prior art keywords
- drug
- acids
- bcs class
- mixture
- acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7084008P | 2008-03-25 | 2008-03-25 | |
| US10653608P | 2008-10-17 | 2008-10-17 | |
| PCT/EP2009/053542 WO2009118356A2 (en) | 2008-03-25 | 2009-03-25 | Preparation method for solid disupersions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE545411T1 true ATE545411T1 (de) | 2012-03-15 |
Family
ID=40996768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT09725902T ATE545411T1 (de) | 2008-03-25 | 2009-03-25 | Herstellungsverfahren für feststoffdispersionen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8216495B2 (de) |
| EP (1) | EP2170289B1 (de) |
| JP (1) | JP2011515444A (de) |
| AT (1) | ATE545411T1 (de) |
| ES (1) | ES2382618T3 (de) |
| WO (1) | WO2009118356A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010253578B2 (en) | 2009-05-27 | 2014-01-30 | Samyang Biopharmaceuticals Corporation | A poorly soluble drug containing microsphere with improved bioavailability and method of preparing the same |
| WO2012035074A1 (en) * | 2010-09-14 | 2012-03-22 | Nanologica Ab | Super-saturating delivery vehicles for poorly water-soluble pharmaceutical and cosmetic active ingredients |
| GB201115635D0 (en) | 2011-09-09 | 2011-10-26 | Univ Liverpool | Compositions of lopinavir and ritonavir |
| GB201115634D0 (en) | 2011-09-09 | 2011-10-26 | Univ Liverpool | Compositions of lopinavir |
| CN103655571B (zh) * | 2012-09-11 | 2016-04-20 | 上海星泰医药科技有限公司 | 一种洛匹那韦和利托那韦复方高均匀度纳米共分散体及其制备方法 |
| US9511341B2 (en) | 2013-08-30 | 2016-12-06 | Sunny Pharmtech Inc. | Method for preparing acetazolamide sodium powder |
| WO2015103230A1 (en) * | 2013-12-31 | 2015-07-09 | Ascendia Pharmaceuticals, Llc | Pharmaceutical compositions for poorly water-soluble compounds |
| PT107846B (pt) * | 2014-08-01 | 2019-03-22 | Hovione Farm S A | Produção de nano- partículas de dispersões sólidas amorfas por co-precipitação controlada |
| EP3193836A1 (de) | 2014-09-15 | 2017-07-26 | PharmaSol GmbH | Aktive geladene teilchenförmige materialien zur topischen verabreichung |
| TWI525110B (zh) | 2014-12-24 | 2016-03-11 | 財團法人工業技術研究院 | 聚合物、及包含其之醫藥組合物 |
| CA2976811C (en) * | 2015-03-10 | 2023-06-27 | Shionogi Inc. | Solid dispersions of ospemifene |
| CA3005127C (en) | 2015-11-18 | 2023-01-24 | Immunovaccine Technologies Inc. | Adjuvanting systems and water-free vaccine compositions comprising a polyi:c polynucleotide adjuvant and a lipid-based adjuvant |
| CN105832680B (zh) * | 2016-05-12 | 2018-12-25 | 沈阳药科大学 | 一种改善螺内酯体外溶出及流动性的药物组合物 |
| US10195214B2 (en) | 2017-03-01 | 2019-02-05 | Corcept Therapeutics, Inc. | Concomitant administration of glucocorticoid receptor modulators and CYP3A inhibitors |
| KR20220144378A (ko) * | 2020-02-19 | 2022-10-26 | 나노 파마솔루션즈, 인코포레이티드 | 치료제 나노입자 및 제조 방법 |
| CN119745837B (zh) * | 2024-12-27 | 2025-11-18 | 湖北中古生物制药有限公司 | 一种多廿烷醇纳米粒速释胶囊的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3839825A1 (de) * | 1988-11-25 | 1990-06-13 | Henning Berlin Gmbh | Feststoffdispersionen enthaltend oxipurinol und/oder seine alkali- oder erdalkalisalze |
| US5985248A (en) * | 1996-12-31 | 1999-11-16 | Inhale Therapeutic Systems | Processes for spray drying solutions of hydrophobic drugs and compositions thereof |
| DE10153934A1 (de) * | 2001-11-06 | 2003-05-22 | Basf Ag | Verfahren zur Kristallisation von Profenen |
| DE10207427A1 (de) * | 2002-02-21 | 2003-09-04 | Basf Ag | Schnelllöslicher Filmüberzug basierend auf Polyvinylalkohol-Polyether-Pfropfcopolymeren in Kombination mit Hydroxy-, Amid-, oder Esterfunktionen enthaltenden Komponenten |
| SI1517899T1 (sl) * | 2002-05-17 | 2008-02-29 | Tibotec Pharm Ltd | Substituirani benzoksazol sulfonamidi sirokega spektra, ki so HIV proteazni inhibitorji |
| KR100592512B1 (ko) * | 2002-11-22 | 2006-07-03 | 서울약품공업(주) | 탐술로신 또는 약제학적으로 허용되는 이의 염을활성성분으로 하는 서방성 배뇨장애 치료제 |
| EP1428526A1 (de) * | 2002-12-13 | 2004-06-16 | Rijksuniversiteit Groningen | Zusammensetzung zur schnellen Freisetzung von lipophilen Stoffen |
| KR100629771B1 (ko) * | 2004-01-27 | 2006-09-28 | 씨제이 주식회사 | 결정성이 감소되거나 무정형화된 올티프라즈의 제조방법 |
| WO2005100315A1 (en) * | 2004-04-08 | 2005-10-27 | Wyeth | Bazedoxifene ascorbate as selective estrogen receptor modulator |
| KR100678824B1 (ko) * | 2005-02-04 | 2007-02-05 | 한미약품 주식회사 | 용해성이 증가된 무정형 타크로리무스 고체분산체 및 이를포함하는 약제학적 조성물 |
| EP1871346A4 (de) * | 2005-04-20 | 2012-07-18 | Ctc Bio Inc | Pharmazeutische zusammensetzung mit freier base aus sibutramin und herstellungsverfahren dafür |
| GB0607105D0 (en) * | 2006-04-10 | 2006-05-17 | Leuven K U Res & Dev | Enhancing solubility and dissolution rate of poorly soluble drugs |
| WO2008080773A1 (de) | 2006-12-29 | 2008-07-10 | Basf Se | Verfahren zur herstellung von festen dosierungsformen enthaltend pfropfcopolymere |
-
2009
- 2009-03-25 AT AT09725902T patent/ATE545411T1/de active
- 2009-03-25 JP JP2011501224A patent/JP2011515444A/ja active Pending
- 2009-03-25 WO PCT/EP2009/053542 patent/WO2009118356A2/en not_active Ceased
- 2009-03-25 US US12/934,232 patent/US8216495B2/en not_active Expired - Fee Related
- 2009-03-25 ES ES09725902T patent/ES2382618T3/es active Active
- 2009-03-25 EP EP09725902A patent/EP2170289B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP2170289B1 (de) | 2012-02-15 |
| EP2170289A2 (de) | 2010-04-07 |
| US8216495B2 (en) | 2012-07-10 |
| ES2382618T3 (es) | 2012-06-11 |
| WO2009118356A2 (en) | 2009-10-01 |
| WO2009118356A3 (en) | 2010-02-18 |
| US20110018154A1 (en) | 2011-01-27 |
| JP2011515444A (ja) | 2011-05-19 |
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