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ATE402925T2 - Neue zusammensetzung enthaltend eine bicyclische verbindung und ein glycerid - Google Patents

Neue zusammensetzung enthaltend eine bicyclische verbindung und ein glycerid Download PDF

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Publication number
ATE402925T2
ATE402925T2 AT04005836T AT04005836T ATE402925T2 AT E402925 T2 ATE402925 T2 AT E402925T2 AT 04005836 T AT04005836 T AT 04005836T AT 04005836 T AT04005836 T AT 04005836T AT E402925 T2 ATE402925 T2 AT E402925T2
Authority
AT
Austria
Prior art keywords
glyceride
composition containing
new composition
bicyclic compound
bicyclic
Prior art date
Application number
AT04005836T
Other languages
English (en)
Inventor
Ryuji Ueno
Tsuyoshi Habe
Original Assignee
Sucampo Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22573018&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE402925(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo Ag filed Critical Sucampo Ag
Application granted granted Critical
Publication of ATE402925T2 publication Critical patent/ATE402925T2/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT04005836T 1999-10-15 2000-10-13 Neue zusammensetzung enthaltend eine bicyclische verbindung und ein glycerid ATE402925T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15954999P 1999-10-15 1999-10-15

Publications (1)

Publication Number Publication Date
ATE402925T2 true ATE402925T2 (de) 2008-08-15

Family

ID=22573018

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00966462T ATE267189T1 (de) 1999-10-15 2000-10-13 Bizyclische verbindungen zusammenstellung und verfahren zu ihrer stabilisierung
AT04005836T ATE402925T2 (de) 1999-10-15 2000-10-13 Neue zusammensetzung enthaltend eine bicyclische verbindung und ein glycerid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT00966462T ATE267189T1 (de) 1999-10-15 2000-10-13 Bizyclische verbindungen zusammenstellung und verfahren zu ihrer stabilisierung

Country Status (26)

Country Link
US (5) US6583174B1 (de)
EP (2) EP1220849B1 (de)
JP (2) JP4332316B2 (de)
KR (1) KR100830061B1 (de)
CN (1) CN1268623C (de)
AR (3) AR026046A1 (de)
AT (2) ATE267189T1 (de)
AU (2) AU780342B2 (de)
BR (1) BRPI0014869B8 (de)
CA (1) CA2385732C (de)
CZ (1) CZ303625B6 (de)
DE (2) DE60039727D1 (de)
DK (2) DK1426361T4 (de)
ES (2) ES2221859T3 (de)
HK (2) HK1066792A1 (de)
HU (2) HU230484B1 (de)
IL (2) IL148803A0 (de)
MX (1) MXPA02003756A (de)
NO (1) NO330258B1 (de)
NZ (1) NZ518020A (de)
PT (2) PT1426361E (de)
RU (1) RU2695274C3 (de)
TR (1) TR200201032T2 (de)
TW (1) TWI281918B (de)
WO (1) WO2001027099A2 (de)
ZA (1) ZA200202312B (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1268623C (zh) * 1999-10-15 2006-08-09 苏坎波公司 组合物和使该组合物稳定的方法
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI331920B (en) * 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
FR2842810B1 (fr) * 2002-07-25 2006-01-27 Inst Nat Sciences Appliq Nouveaux composes gem difluores, leur procedes de preparation et leurs applications.
WO2004037268A1 (en) * 2002-10-23 2004-05-06 Sucampo Ag Prostaglandin compounds for the treatment of obesity
BRPI0317740B8 (pt) * 2002-12-27 2021-05-25 Sucampo Ag uso do composto 13,14-diidro-15-ceto-16,16-diflúorprostaglandina e1
WO2005002588A1 (en) * 2003-07-03 2005-01-13 Sucampo Ag Enteric coated composition comprising prostaglandin analogs as chloride channel opener
TWI495471B (zh) * 2003-08-12 2015-08-11 R Tech Ueno Ltd 促進毛髮生長之組成物及方法
TWI387454B (zh) 2004-09-02 2013-03-01 Sucampo Ag 治療胃腸道疾病之方法及組成物
PL1871380T3 (pl) * 2005-04-12 2012-03-30 Sucampo Ag Zastosowanie kombinacji związku prostaglandyny i inhibitora pompy protonowej w leczeniu zaburzeń żołądkowo-jelitowych
BRPI0707334B8 (pt) 2006-01-24 2021-05-25 R Tech Ueno Ltd formulação de cápsula de gelatina mole de um composto 15-ceto-prostaglandina e método para estabilização do um composto 15-cetoprostaglandina
EP2682130A1 (de) * 2006-01-24 2014-01-08 R-Tech Ueno, Ltd. Pharmazeutische Zusammensetzung mit einer bicyclischen Verbindung sowie Verfahren zur Stabilisierung der bicyclischen Verbindung
KR101437302B1 (ko) * 2006-02-07 2014-09-02 가부시키가이샤 아루떼꾸 우에노 프로스타글란딘 유도체의 제조 방법
US20090012165A1 (en) 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
US20090030072A1 (en) 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
AU2008276840B2 (en) * 2007-07-19 2013-10-03 R-Tech Ueno, Ltd. Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
CN101318948B (zh) * 2008-04-01 2011-04-27 上海天伟生物制药有限公司 鲁比前列酮晶体、其制备方法及用途
US8569279B2 (en) * 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
ES2567328T3 (es) 2009-07-28 2016-04-21 Ono Pharmaceutical Co., Ltd. Compuesto bicíclico y uso del mismo para fines médicos
AU2010295464B2 (en) * 2009-09-18 2015-11-26 Merck Sharp & Dohme Corp. Use of opioid receptor antagonist for gastrointestinal tract disorders
CA2779736A1 (en) 2009-11-03 2011-05-12 Bernard Charles Sherman Stable pharmaceutical formulations comprising lubiprostone
ES2581852T3 (es) * 2011-01-27 2016-09-07 Ono Pharmaceutical Co., Ltd. Compuesto bicíclico y uso del mismo para fines médicos
EP2669279B1 (de) 2011-01-27 2017-01-11 ONO Pharmaceutical Co., Ltd. Bizyklische verbindung und ihre verwendung für medizinische zwecke
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
US10736871B2 (en) 2015-04-01 2020-08-11 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
JP6954282B2 (ja) 2016-06-30 2021-10-27 小野薬品工業株式会社 二環式化合物の製造方法
US11534404B2 (en) 2016-10-06 2022-12-27 Sucampo Ag Multilayer beads for pharmaceutical use
JPWO2019221215A1 (ja) * 2018-05-18 2021-05-27 ニプロ株式会社 ルビプロストン含有粒子状医薬組成物
JP7518661B2 (ja) 2020-05-14 2024-07-18 沢井製薬株式会社 ルビプロストン含有整粒物、ルビプロストン含有錠剤およびそれらの製造方法

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US18202A (en) * 1857-09-15 Improvement in feathering paddle-wheels
JPS5720305B2 (de) 1973-02-28 1982-04-27
US4034003A (en) 1974-04-11 1977-07-05 Ono Pharmaceutical Co., Ltd. 15-Cycloalkyl-prostaglandins
US3966962A (en) 1975-03-27 1976-06-29 The Upjohn Company Triacetin solutions of PGE-type compounds
JPS5350141A (en) * 1976-10-18 1978-05-08 Ono Pharmaceut Co Ltd Stabilization of prostaglandin and prostaglandin analogues
JPS5919524B2 (ja) 1976-12-17 1984-05-07 中外製薬株式会社 安定な１α−ヒドロキシビタミンＤ類含有製剤
JPS5391110A (en) 1977-01-20 1978-08-10 Yamanouchi Pharmaceut Co Ltd Novel drug composition for rectal infusion
CA1184906A (en) * 1977-04-19 1985-04-02 Roy A. Johnson 9-deoxy-5,9-epoxy-prostaglandins
JPS6022708B2 (ja) 1977-07-14 1985-06-03 小野薬品工業株式会社 プロスタグランジン類似化合物
JPS5452717A (en) * 1977-09-29 1979-04-25 Chugai Pharmaceut Co Ltd Stable oily pharmaceuticals containing 1alpha-hydroxyvitamin d
US4130566A (en) 1977-10-27 1978-12-19 Sumitomo Chemical Company, Limited Process for producing 5-carboxy-2-acetylthiophene
AT358530B (de) 1978-04-25 1980-09-10 Plc Pharma Licences Stabilisierungsverfahren
JPS55136219A (en) 1979-04-11 1980-10-23 Sumitomo Chem Co Ltd Diazepam oily drug
US4670569A (en) 1981-04-02 1987-06-02 G. D. Searle & Co. 5-fluoro-PGI2 compounds
JPS59137413A (ja) * 1983-01-25 1984-08-07 Teijin Ltd ７−チアプロスタグランジンｅ↓１類を含有する医薬品組成物
US4579958A (en) 1983-12-23 1986-04-01 G. D. Searle & Co. 5-fluoro-3-oxa-6,7-didehydro-PGI1 compounds
US4687864A (en) 1983-12-23 1987-08-18 G. D. Searle & Co. 5-fluoro-3-oxa-prostacyclin compounds
US5428062A (en) 1987-01-28 1995-06-27 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti ulcers containing same
US5225439A (en) 1987-01-28 1993-07-06 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti ulcers containing same
US5166174A (en) * 1987-01-28 1992-11-24 K.K. Ueno Seiyaku Oyo Kenkyujo Prostaglandins E and anti-ulcers containing same
US4758880A (en) 1987-03-27 1988-07-19 The Grass Valley Group, Inc. Video matte generator
ATE109970T1 (de) 1987-09-03 1994-09-15 Univ Georgia Res Found Cyclosporin-augenmittel.
GB2210556B (en) 1987-10-02 1991-07-17 Ueno Seiyaku Oyo Kenkyujo Kk The use of 15-keto-16-halo-prostaglandins in cathartic compositions
US5317032A (en) * 1987-10-02 1994-05-31 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Prostaglandin cathartic
JP2597649B2 (ja) † 1988-05-11 1997-04-09 株式会社上野製薬応用研究所 気管・気管支拡張剤
PT90888B (pt) * 1988-06-17 1994-12-30 Wellcome Found Processo para a preparacao de composicoes farmaceuticas contendo prostaglandinas
JP2579193B2 (ja) 1988-07-19 1997-02-05 小野薬品工業株式会社 １６，１６−ジフルオロ−１５−オキソ−１５−デオキシｐｇｅ誘導体
JPH0745504B2 (ja) * 1988-07-29 1995-05-17 株式会社上野製薬応用研究所 プロスタグランジン前駆体およびその製法
JP2794433B2 (ja) 1989-02-02 1998-09-03 丸善製薬株式会社 甘草疎水性フラボノイド製剤
CA2030346C (en) † 1989-11-22 2000-04-11 Ryuji Ueno Treatment of cardiac dysfunction with 15-keto-prostaglandin compounds
US5256696A (en) 1989-11-22 1993-10-26 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of cardiac dysfunction with 15-ketoprostaglandin compounds
CA2030344C (en) † 1989-11-22 2000-04-18 Ryuji Ueno Treatment of pulmonary dysfunction with 15-keto-prostaglandin compounds
CA2030345C (en) 1989-11-22 1998-12-08 Ryuji Ueno Use of 15-keto-prostaglandin compound for improvement of encephalic function
US5254588A (en) * 1989-11-22 1993-10-19 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of pulmonary dysfunction with 15-ketoprostaglandin compounds
ATE174221T1 (de) * 1990-05-01 1998-12-15 R Tech Ueno Ltd Behandlung von pankreaskrankheit mit 15-keto- prostaglandin e-derivaten
JPH0446122A (ja) 1990-06-13 1992-02-17 Nippon Iyakuhin Kogyo Kk 活性型ビタミンｄ↓３類含有製剤
CA2046069C (en) 1990-07-10 2002-04-09 Ryuji Ueno Treatment of inflammatory diseases with 15-keto-prostaglandin compounds
JP2938579B2 (ja) 1990-12-15 1999-08-23 株式会社上野製薬応用研究所 消化管壁保護剤
US5274130A (en) * 1991-09-03 1993-12-28 R-Tech Ueno Ltd. Process for production of prostaglandin intermediates
JP2746800B2 (ja) * 1991-09-03 1998-05-06 株式会社アールテック・ウエノ プロスタグランジン中間体の製法
US5474979A (en) 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
CA2150287C (en) * 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
US5981607A (en) 1998-01-20 1999-11-09 Allergan Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers
CN1268623C (zh) * 1999-10-15 2006-08-09 苏坎波公司 组合物和使该组合物稳定的方法
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
JP4210631B2 (ja) 2004-06-24 2009-01-21 株式会社日立製作所 ブレーキ制御装置

Also Published As

Publication number Publication date
US6583174B1 (en) 2003-06-24
US20120095090A1 (en) 2012-04-19
ES2309410T3 (es) 2008-12-16
AU2004242503B2 (en) 2007-06-21
CZ303625B6 (cs) 2013-01-16
AU2004242503C1 (en) 2005-01-27
AR026046A1 (es) 2002-12-26
WO2001027099A2 (en) 2001-04-19
HK1045693B (zh) 2005-01-21
CN1268623C (zh) 2006-08-09
KR100830061B1 (ko) 2008-05-16
IL148803A0 (en) 2002-09-12
HUP0203746A2 (hu) 2003-03-28
EP1426361B2 (de) 2015-02-25
NZ518020A (en) 2004-02-27
RU2695274C3 (ru) 2020-11-09
EP1426361B1 (de) 2008-07-30
AU2004242503A1 (en) 2005-01-27
US20080255227A1 (en) 2008-10-16
BR0014869A (pt) 2002-06-25
ATE267189T1 (de) 2004-06-15
NO330258B1 (no) 2011-03-14
RU2695274C9 (ru) 2020-01-22
JP4332316B2 (ja) 2009-09-16
US8097649B1 (en) 2012-01-17
DK1426361T4 (en) 2015-03-16
KR20020068521A (ko) 2002-08-27
US8088934B2 (en) 2012-01-03
HU229547B1 (en) 2014-01-28
HU230484B1 (hu) 2016-07-28
JP2003511445A (ja) 2003-03-25
US20040235885A1 (en) 2004-11-25
ZA200202312B (en) 2002-12-24
AU7685600A (en) 2001-04-23
AR109354A2 (es) 2018-11-21
DK1426361T3 (da) 2008-11-17
NO20021736D0 (no) 2002-04-12
PT1220849E (pt) 2004-10-29
TWI281918B (en) 2007-06-01
MXPA02003756A (es) 2005-09-08
ES2221859T3 (es) 2005-01-16
HK1066792A1 (en) 2005-04-01
EP1426361A1 (de) 2004-06-09
AU780342B2 (en) 2005-03-17
PT1426361E (pt) 2008-10-08
AR089848A2 (es) 2014-09-24
US7417067B2 (en) 2008-08-26
DE60039727D1 (de) 2008-09-11
RU2002112984A (ru) 2004-01-20
WO2001027099A3 (en) 2001-10-25
CA2385732A1 (en) 2001-04-19
EP1220849B1 (de) 2004-05-19
CN1379769A (zh) 2002-11-13
HUP1300369A2 (de) 2003-03-28
EP1220849A2 (de) 2002-07-10
DK1220849T3 (da) 2004-09-27
IL148803A (en) 2006-07-05
JP2009235079A (ja) 2009-10-15
NO20021736L (no) 2002-04-12
DE60010913T2 (de) 2005-06-09
BRPI0014869B8 (pt) 2021-05-25
HK1045693A1 (en) 2002-12-06
TR200201032T2 (tr) 2002-08-21
ES2309410T5 (es) 2015-03-17
CA2385732C (en) 2009-02-10
RU2695274C2 (ru) 2019-07-22
CZ20021037A3 (cs) 2002-09-11
HUP0203746A3 (en) 2005-02-28
BRPI0014869B1 (pt) 2017-06-13
DE60010913D1 (de) 2004-06-24

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