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ATE380026T1 - Alpha-aminoamid-derivate als mittel gegen migräne - Google Patents

Alpha-aminoamid-derivate als mittel gegen migräne

Info

Publication number
ATE380026T1
ATE380026T1 AT03772344T AT03772344T ATE380026T1 AT E380026 T1 ATE380026 T1 AT E380026T1 AT 03772344 T AT03772344 T AT 03772344T AT 03772344 T AT03772344 T AT 03772344T AT E380026 T1 ATE380026 T1 AT E380026T1
Authority
AT
Austria
Prior art keywords
alpha
aminoamide derivatives
migraines
conditions
against migraines
Prior art date
Application number
AT03772344T
Other languages
English (en)
Inventor
Patricia Salvati
Marcello Calabresi
Luciano Dho
Orietta Veneroni
Piero Melloni
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Application granted granted Critical
Publication of ATE380026T1 publication Critical patent/ATE380026T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AT03772344T 2003-01-16 2003-11-18 Alpha-aminoamid-derivate als mittel gegen migräne ATE380026T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03000921A EP1438956A1 (de) 2003-01-16 2003-01-16 Alpha-Aminoamidderivate die als Antimigränemittel nützlich sind

Publications (1)

Publication Number Publication Date
ATE380026T1 true ATE380026T1 (de) 2007-12-15

Family

ID=32524140

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03772344T ATE380026T1 (de) 2003-01-16 2003-11-18 Alpha-aminoamid-derivate als mittel gegen migräne

Country Status (21)

Country Link
US (2) US7709523B2 (de)
EP (2) EP1438956A1 (de)
JP (1) JP4885455B2 (de)
KR (1) KR101049694B1 (de)
CN (1) CN100418517C (de)
AT (1) ATE380026T1 (de)
AU (1) AU2003279399B8 (de)
BR (1) BRPI0317795B8 (de)
CA (1) CA2510514C (de)
CY (1) CY1107274T1 (de)
DE (1) DE60317935T2 (de)
DK (1) DK1585510T3 (de)
ES (1) ES2295658T3 (de)
HK (1) HK1086487A1 (de)
MX (1) MXPA05007339A (de)
NO (1) NO333610B1 (de)
NZ (1) NZ541117A (de)
PT (1) PT1585510E (de)
RU (1) RU2336077C2 (de)
SI (1) SI1585510T1 (de)
WO (1) WO2004062655A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
ATE317280T1 (de) * 2001-09-03 2006-02-15 Newron Pharm Spa Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung
ES2339021T3 (es) * 2003-08-25 2010-05-14 Newron Pharmaceuticals S.P.A. Derivados de alfa-aminoamida utiles como agentes antiinflamatorios.
RS51411B (en) * 2004-09-10 2011-02-28 Newron Pharmaceuticals S.P.A. USE (R) - (HALOBENZYLOXY) BENZYLAMINO-PROPANAMIDE AS SELECTIVE MODULATORS OF SODIUM AND / OR CALCIUM CHANNELS
HUE028329T2 (en) 2005-12-22 2016-12-28 Newron Pharm Spa 2-Phenylethylamino derivatives acting as calcium and / or sodium channel modulators
EA017123B1 (ru) 2006-06-19 2012-10-30 Ньюрон Фармасьютикалс С.П.А. Способ получения 2-[4-(3- и 2-фторбензилокси)бензиламино]пропанамидов
FR2903985B1 (fr) 2006-07-24 2008-09-05 Sanofi Aventis Sa Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
CA2689561C (en) 2007-06-15 2015-11-17 Newron Pharmaceuticals S.P.A. Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
CA2936209C (en) * 2007-12-11 2020-02-11 Newron Pharmaceuticals S.P.A. Process for the production of 2-[4-(3- or 2-fluorobenzyloxy)benzylamino]propanamides with high purity degree
EP2314569A1 (de) 2009-10-22 2011-04-27 Merck Patent GmbH Neuartige polymorphe Formen von (S)-2-[4-(3-Fluor-benzyloxy)-benzylamino]-Propionamidmesylatsalz und Herstellungsverfahren dafür
DK2563355T3 (en) * 2010-04-27 2016-09-12 Newron Pharm Spa A process for the preparation of ralfinamide-methanesulphonate or R-enantiomers thereof.
KR101705718B1 (ko) * 2013-12-30 2017-02-14 이화여자대학교 산학협력단 신규한 아미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 통증의 예방 또는 치료용 약학적 조성물
CN107522654B (zh) * 2016-06-21 2020-09-01 中国人民解放军军事医学科学院毒物药物研究所 新的α-氨基酰胺衍生物及其医药用途
WO2019205147A1 (zh) * 2018-04-28 2019-10-31 上海璃道医药科技有限公司 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途
CN112716927B (zh) * 2020-10-12 2022-10-14 复旦大学 α-氨基酰胺类化合物及其制备方法与应用

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GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AU754681B2 (en) * 1998-02-04 2002-11-21 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
JP2000191533A (ja) * 1998-10-19 2000-07-11 Eisai Co Ltd 鎮痛剤
CN1148188C (zh) * 1998-10-19 2004-05-05 卫材株式会社 镇痛剂
US6281211B1 (en) * 1999-02-04 2001-08-28 Euro-Celtique S.A. Substituted semicarbazides and the use thereof
KR20020015308A (ko) * 1999-03-26 2002-02-27 추후보정 아릴 치환된 피라졸, 이미다졸, 옥사졸, 티아졸 및 피롤,및 이의 용도
EP1169060B1 (de) 1999-04-09 2005-08-31 Euro-Celtique S.A. Natrium kanalblocker zusammensetzungen und deren verwendung
ATE317280T1 (de) * 2001-09-03 2006-02-15 Newron Pharm Spa Pharmazeutische zusammensetzung mit gabapentin oder deren analog und einem alpha-aminoamid und analgetische verwendung dieser zusammensetzung
AR044007A1 (es) * 2003-04-11 2005-08-24 Newron Pharmaceuticals Inc Metodos para el tratamiento de la enfermedad de parkinson
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RS51411B (en) * 2004-09-10 2011-02-28 Newron Pharmaceuticals S.P.A. USE (R) - (HALOBENZYLOXY) BENZYLAMINO-PROPANAMIDE AS SELECTIVE MODULATORS OF SODIUM AND / OR CALCIUM CHANNELS

Also Published As

Publication number Publication date
US20100267835A1 (en) 2010-10-21
HK1086487A1 (en) 2006-09-22
AU2003279399B2 (en) 2008-11-27
CY1107274T1 (el) 2012-11-21
NO20053780D0 (no) 2005-08-09
CA2510514C (en) 2011-07-26
NZ541117A (en) 2008-02-29
ES2295658T3 (es) 2008-04-16
NO20053780L (no) 2005-10-13
EP1585510A1 (de) 2005-10-19
CN1738611A (zh) 2006-02-22
DE60317935D1 (de) 2008-01-17
AU2003279399B8 (en) 2009-01-29
DK1585510T3 (da) 2008-02-25
JP4885455B2 (ja) 2012-02-29
NO333610B1 (no) 2013-07-22
JP2006514060A (ja) 2006-04-27
RU2005125919A (ru) 2006-01-10
KR101049694B1 (ko) 2011-07-19
AU2003279399A1 (en) 2004-08-10
SI1585510T1 (sl) 2008-04-30
MXPA05007339A (es) 2005-09-30
EP1438956A1 (de) 2004-07-21
PT1585510E (pt) 2008-02-28
EP1585510B1 (de) 2007-12-05
KR20050094852A (ko) 2005-09-28
CA2510514A1 (en) 2004-07-29
BR0317795A (pt) 2005-11-22
RU2336077C2 (ru) 2008-10-20
DE60317935T2 (de) 2008-11-27
WO2004062655A1 (en) 2004-07-29
BRPI0317795B1 (pt) 2019-04-02
BRPI0317795B8 (pt) 2021-05-25
CN100418517C (zh) 2008-09-17
US7709523B2 (en) 2010-05-04
US20060079570A1 (en) 2006-04-13

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