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ATE258930T1 - Dihydrobenzifurane - Google Patents

Dihydrobenzifurane

Info

Publication number
ATE258930T1
ATE258930T1 AT98966288T AT98966288T ATE258930T1 AT E258930 T1 ATE258930 T1 AT E258930T1 AT 98966288 T AT98966288 T AT 98966288T AT 98966288 T AT98966288 T AT 98966288T AT E258930 T1 ATE258930 T1 AT E258930T1
Authority
AT
Austria
Prior art keywords
dihydrobenzifurans
meaningand
heterocycle
meanings
compounds
Prior art date
Application number
AT98966288T
Other languages
English (en)
Inventor
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Dietrich Haefner
Rolf Beume
Hans-Peter Kley
Hendrik Timmerman
Der Laan Ivonne Johanna Van
Wolf-Ruediger Ulrich
Geert Jan Sterk
Der Mey Margaretha Van
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of ATE258930T1 publication Critical patent/ATE258930T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT98966288T 1997-12-15 1998-12-10 Dihydrobenzifurane ATE258930T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
PCT/EP1998/008054 WO1999031090A1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (1)

Publication Number Publication Date
ATE258930T1 true ATE258930T1 (de) 2004-02-15

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98966288T ATE258930T1 (de) 1997-12-15 1998-12-10 Dihydrobenzifurane

Country Status (17)

Country Link
US (1) US6380196B1 (de)
EP (1) EP1042319B1 (de)
JP (1) JP2002508368A (de)
AT (1) ATE258930T1 (de)
AU (1) AU753576B2 (de)
CA (1) CA2314111A1 (de)
CZ (1) CZ299304B6 (de)
DE (1) DE69821530T2 (de)
DK (1) DK1042319T3 (de)
EE (1) EE04312B1 (de)
ES (1) ES2216349T3 (de)
HU (1) HU225114B1 (de)
IL (1) IL136359A (de)
PL (1) PL191236B1 (de)
PT (1) PT1042319E (de)
SI (1) SI1042319T1 (de)
WO (1) WO1999031090A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE320800T1 (de) 1999-08-21 2006-04-15 Altana Pharma Ag Synergistische kombination von roflumilast und salmeterol
AU7654200A (en) * 1999-09-14 2001-04-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
TR200201128T2 (tr) 1999-10-25 2002-08-21 Byk Gulden Lomberg Chemische Fabrik Gmbh PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri.
JP2003512459A (ja) * 1999-10-25 2003-04-02 アルタナ ファルマ アクチエンゲゼルシャフト Pde4インヒビターとしてのフタラジノン誘導体
EP1296956A1 (de) 2000-06-05 2003-04-02 ALTANA Pharma AG Als beta-2-adrenorezeptor-agonisten als auch als pde-4-hemmer wirkende verbindungen
WO2002064584A1 (en) * 2001-02-15 2002-08-22 Altana Pharma Ag Phthalayinone-piperidino-derivatives as pde4 inhibitors
US7022696B2 (en) * 2001-04-25 2006-04-04 Altana Pharma Ag Piperazino-derivatives and their use as PDE4 inhibitor
CN1503792A (zh) 2001-04-25 2004-06-09 ��̹��ҽҩ��˾ 新的酞嗪酮
JP2005521711A (ja) * 2002-03-29 2005-07-21 中外製薬株式会社 呼吸器疾病の予防または治療のための医薬組成物
WO2004018451A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Pyridazinone-derivatives as pde4 inhibitors
DE60313472T2 (de) * 2002-08-10 2008-01-24 Nycomed Gmbh Pyrrolidindion-substituierte piperidin-phthalazone als pde4-inhibitoren
WO2004018449A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
CA2494643A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-n-oxide-derivatives
EP1624893A2 (de) 2003-04-01 2006-02-15 Applied Research Systems ARS Holding N.V. Phosphodiesterase inhibitoren in der unfruchtbarkeit
CA2554797C (en) * 2004-02-04 2012-09-04 Altana Pharma Ag 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-one derivatives as pde4 inhibitors
EP1716123A1 (de) * 2004-02-04 2006-11-02 Altana Pharma AG Pyridazinonderivate und deren verwendung als pde4-inhibitoren
WO2006095666A1 (ja) * 2005-03-07 2006-09-14 Kyorin Pharmaceutical Co., Ltd. ピラゾロピリジン-4-イルピリダジノン誘導体とその付加塩及びそれらを有効成分とするpde阻害剤
EP1953147A1 (de) * 2005-11-21 2008-08-06 Japan Tobacco, Inc. Heterocyclische verbindung und deren medizinische anwendung
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
DK0469013T3 (da) * 1989-04-17 1995-10-02 Byk Gulden Lomberg Chem Fab Hidtil ukendte arylpyridaziner, fremstilling deraf, anvendelse deraf og lægemidler indeholdende disse
JP3120857B2 (ja) 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
AU8722991A (en) * 1990-10-16 1992-05-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Arylpyridazinones
WO1992019602A1 (de) * 1991-04-26 1992-11-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridazine
EP0593567B1 (de) * 1991-07-05 1996-08-28 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung substituierter pyridazine gegen dermatosen
JP3245165B2 (ja) * 1991-10-09 2002-01-07 シンテックス(ユー・エス・エイ)・インコーポレイテッド ピリドピリダジノンおよびピリダジンチオン化合物
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
CA2400368A1 (en) 1992-12-02 1994-06-09 Allen J. Duplantier Catechol diethers as selective pde iv inhibitors
US5476834A (en) * 1993-03-17 1995-12-19 Sumitomo Chemical Company, Limited Dihydrobenzofuran derivatives, their production and use
US6121274A (en) * 1994-07-22 2000-09-19 Byk Gulden Lomberg Chemische Fabrik Gmbh Dihydrobenzofurane
ES2224130T3 (es) 1994-08-09 2005-03-01 Eisai Co., Ltd. Compuesto de piridazina condensada.
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
JP2002508368A (ja) 2002-03-19
CZ20002218A3 (cs) 2000-11-15
EP1042319A1 (de) 2000-10-11
DK1042319T3 (da) 2004-06-01
WO1999031090A1 (en) 1999-06-24
EE04312B1 (et) 2004-06-15
EE200000335A (et) 2001-10-15
DE69821530D1 (de) 2004-03-11
HUP0004561A3 (en) 2002-04-29
ES2216349T3 (es) 2004-10-16
DE69821530T2 (de) 2004-12-23
CA2314111A1 (en) 1999-06-24
PL341239A1 (en) 2001-03-26
US6380196B1 (en) 2002-04-30
IL136359A0 (en) 2001-06-14
EP1042319B1 (de) 2004-02-04
PT1042319E (pt) 2004-06-30
AU2270199A (en) 1999-07-05
HUP0004561A2 (hu) 2002-03-28
CZ299304B6 (cs) 2008-06-11
HU225114B1 (en) 2006-06-28
AU753576B2 (en) 2002-10-24
IL136359A (en) 2003-03-12
SI1042319T1 (en) 2004-08-31
PL191236B1 (pl) 2006-04-28

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