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ATE177008T1 - Verwendung von toremifene für die behandlung von sle - Google Patents

Verwendung von toremifene für die behandlung von sle

Info

Publication number
ATE177008T1
ATE177008T1 AT93923058T AT93923058T ATE177008T1 AT E177008 T1 ATE177008 T1 AT E177008T1 AT 93923058 T AT93923058 T AT 93923058T AT 93923058 T AT93923058 T AT 93923058T AT E177008 T1 ATE177008 T1 AT E177008T1
Authority
AT
Austria
Prior art keywords
treatment
toremifene
sle
glucocorticoid
estrogen
Prior art date
Application number
AT93923058T
Other languages
English (en)
Inventor
Junpei Itoh
Osamu Miyazaki
Hisao Ekimoto
Michinori Koyama
Tetsushi Saino
Lauri Kangas
Anni Warri
Christer Granberg
Original Assignee
Nippon Kayaku Kk
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Kk, Orion Yhtymae Oy filed Critical Nippon Kayaku Kk
Application granted granted Critical
Publication of ATE177008T1 publication Critical patent/ATE177008T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
AT93923058T 1992-10-27 1993-10-26 Verwendung von toremifene für die behandlung von sle ATE177008T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31077292 1992-10-27

Publications (1)

Publication Number Publication Date
ATE177008T1 true ATE177008T1 (de) 1999-03-15

Family

ID=18009292

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93923058T ATE177008T1 (de) 1992-10-27 1993-10-26 Verwendung von toremifene für die behandlung von sle

Country Status (12)

Country Link
US (3) US6355688B1 (de)
EP (2) EP0667768B1 (de)
KR (1) KR100303634B1 (de)
CN (1) CN1053337C (de)
AT (1) ATE177008T1 (de)
AU (1) AU5286693A (de)
DE (1) DE69323759T2 (de)
DK (1) DK0667768T3 (de)
ES (1) ES2128441T3 (de)
GR (1) GR3029682T3 (de)
NO (2) NO314533B1 (de)
WO (1) WO1994009764A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
JPH08510451A (ja) * 1993-05-13 1996-11-05 ネオルックス コーポレイション 異常増殖性平滑筋細胞に関連した病因の予防及び治療
US5521198A (en) * 1993-12-21 1996-05-28 Eli Lilly And Company Methods of inhibiting autoimmune diseases
CA2280181A1 (en) * 1997-02-09 1998-08-13 Pharmos Corporation Enhanced anti-angiogenic activity of permanently charged derivatives of steroid hormones
JP2002501624A (ja) 1997-03-06 2002-01-15 ナシュア コーポレイション 偏光維持拡散シートを用いたディスプレイ
US6117911A (en) 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
WO2001012206A2 (de) * 1999-08-13 2001-02-22 Heinrich Wieland Soja-glycine extracten und aromatase-hemendern zur positiven beeinflussung von kollagen
US20020013327A1 (en) * 2000-04-18 2002-01-31 Lee Andrew G. Compositions and methods for treating female sexual dysfunction
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US7069444B2 (en) * 2002-01-25 2006-06-27 Brent A. Lowensohn Portable wireless access to computer-based systems
US9040507B2 (en) * 2008-06-02 2015-05-26 Novelmed Therapeutics, Inc. Method for treating inflammatory conditions
AU2010210346B2 (en) 2009-02-09 2015-07-09 Swimc Llc In-store tintable non-infrared-absorptive paint and stain system
CN102307795B (zh) 2009-02-09 2015-04-15 威士伯采购公司 在店内可调色的不吸收红外线的漆料和色料系统
EP2588543A1 (de) 2010-07-01 2013-05-08 Valspar Sourcing, Inc. Infrarotreflektierende zweiteilige beschichtungszusammensetzung
AU2011337167B2 (en) 2010-10-20 2016-08-04 Swimc Llc Water-based coating system with improved moisture and heat resistance
RU2572504C1 (ru) * 2013-12-26 2016-01-10 Андрей Константинович Иорданишвили Способ лечения лучевой сиалоаденопатии
CA3015631C (en) 2016-02-23 2023-10-17 Advanced Environmental Recycling Technologies, Inc. Compositions and methods for reducing the surface temperature of composite articles
US20190322123A1 (en) 2017-01-01 2019-10-24 Advanced Environmental Recycling Technologies, Inc. Methods for coating composite articles

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU172948B (hu) 1976-02-05 1979-01-28 Gyogyszerkutato Intezet Sposob poluchenija osnovnykh proizvodnykh trifenil-alkenov
EP0002097B1 (de) 1977-08-22 1981-08-05 Imperial Chemical Industries Plc Triphenylalken-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen, die sie enthalten
DE3046719C2 (de) 1980-12-11 1983-02-17 Klinge Pharma GmbH, 8000 München 1,1,2-Triphenyl-but-1-en-Derivate, Verfahren zu ihrer Herstellung und Arzneimittel
FI67538C (fi) 1982-05-27 1985-04-10 Farmos Oy Foerfarande foer framstaellning av (z)-1,2-difenyl-1-(4-(2-(n n-dimetylamino)etoxi)fenyl)-1-buten
GB2126576B (en) * 1982-06-25 1985-06-19 Farmos Group Limited Alkane and alkene derivatives
US5348729A (en) * 1988-11-30 1994-09-20 The United States Of America As Represented By The Department Of Health And Human Services Evaluative means for detecting inflammatory reactivity
US4990538A (en) * 1989-08-23 1991-02-05 Harris Adrian L Use of toremifene and its metabolites for the reversal of multidrug resistance of cancer cells against cytotoxic drugs
JPH04312526A (ja) * 1991-04-09 1992-11-04 Fujisawa Pharmaceut Co Ltd 骨疾患治療剤

Also Published As

Publication number Publication date
ES2128441T3 (es) 1999-05-16
CN1100930A (zh) 1995-04-05
WO1994009764A1 (en) 1994-05-11
DE69323759D1 (de) 1999-04-08
GR3029682T3 (en) 1999-06-30
EP0776661A1 (de) 1997-06-04
DK0667768T3 (da) 1999-09-27
NO317544B1 (no) 2004-11-08
EP0667768B1 (de) 1999-03-03
US6355688B1 (en) 2002-03-12
EP0667768A1 (de) 1995-08-23
NO314533B1 (no) 2003-04-07
NO951596L (no) 1995-04-26
KR940008677A (ko) 1994-05-16
NO951596D0 (no) 1995-04-26
DE69323759T2 (de) 1999-07-22
AU5286693A (en) 1994-05-24
CN1053337C (zh) 2000-06-14
US6387958B1 (en) 2002-05-14
US6458848B1 (en) 2002-10-01
US20020107231A1 (en) 2002-08-08
NO20025179L (no) 1995-04-26
KR100303634B1 (ko) 2001-11-22
NO20025179D0 (no) 2002-10-28

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee