[go: up one dir, main page]

AR128119A1 - Método para producir n-alquilaminoácido y péptido que contiene n-alquilaminoácido - Google Patents

Método para producir n-alquilaminoácido y péptido que contiene n-alquilaminoácido

Info

Publication number
AR128119A1
AR128119A1 ARP220103601A ARP220103601A AR128119A1 AR 128119 A1 AR128119 A1 AR 128119A1 AR P220103601 A ARP220103601 A AR P220103601A AR P220103601 A ARP220103601 A AR P220103601A AR 128119 A1 AR128119 A1 AR 128119A1
Authority
AR
Argentina
Prior art keywords
ester
acid
alkylaminoacid
monoalkylamino
producing
Prior art date
Application number
ARP220103601A
Other languages
English (en)
Inventor
Shio Komiya
Zengye Hou
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of AR128119A1 publication Critical patent/AR128119A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se proporciona un método para producir un N-monoalquilaminoácido o un éster de este o un péptido que contiene el N-monoalquilaminoácido o un éster de este, el método que comprende un paso de alquilación que consiste en mezclar un aminoácido inicial o un éster de este o un péptido que contiene el aminoácido inicial o un éster de este, un agente alquilante primario C₁-C₆ o un haluro de metilo sustituido y un catalizador en un disolvente en la presencia de hidrógeno, donde el paso de alquilación se lleva a cabo a una presión de 1 atm o más y produce un N-monoalquilaminoácido o un éster de este o un péptido que contiene el N-monoalquilaminoácido o un éster de este en el cual un grupo alquilo primario correspondiente al agente alquilante primario C₁-C₆ o el haluro de metilo sustituido se une a un grupo amino del aminoácido inicial o un éster de este.
ARP220103601A 2021-12-28 2022-12-27 Método para producir n-alquilaminoácido y péptido que contiene n-alquilaminoácido AR128119A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021214900 2021-12-28
JP2022168608 2022-10-20

Publications (1)

Publication Number Publication Date
AR128119A1 true AR128119A1 (es) 2024-03-27

Family

ID=86999039

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP220103601A AR128119A1 (es) 2021-12-28 2022-12-27 Método para producir n-alquilaminoácido y péptido que contiene n-alquilaminoácido

Country Status (10)

Country Link
EP (1) EP4414374A1 (es)
JP (2) JP7430297B2 (es)
KR (1) KR20240113971A (es)
AR (1) AR128119A1 (es)
AU (1) AU2022428318A1 (es)
CA (1) CA3237911A1 (es)
IL (1) IL312468A (es)
MX (1) MX2024008002A (es)
TW (1) TW202342495A (es)
WO (1) WO2023127869A1 (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1010063C2 (nl) 1998-09-10 2000-03-13 Holland Sweetener Co Werkwijze voor de bereiding van neotaam.
JP7232758B2 (ja) 2017-06-09 2023-03-06 中外製薬株式会社 膜透過性の高い環状ペプチド化合物、及びこれを含むライブラリ
CN118184532A (zh) 2018-12-12 2024-06-14 中外制药株式会社 具有能形成分子内氢键的官能团的氨基酸、包含该氨基酸的肽化合物、及其制备方法
KR20210139366A (ko) 2019-03-15 2021-11-22 추가이 세이야쿠 가부시키가이샤 방향족 아미노산 유도체의 제조 방법
AR120394A1 (es) * 2019-11-07 2022-02-09 Chugai Pharmaceutical Co Ltd Compuesto de péptido cíclico que tiene acción inhibitoria de kras

Also Published As

Publication number Publication date
AU2022428318A1 (en) 2024-05-16
JP7430297B2 (ja) 2024-02-09
CA3237911A1 (en) 2023-07-06
WO2023127869A1 (ja) 2023-07-06
MX2024008002A (es) 2024-07-12
IL312468A (en) 2024-06-01
KR20240113971A (ko) 2024-07-23
EP4414374A1 (en) 2024-08-14
JP2024052694A (ja) 2024-04-11
TW202342495A (zh) 2023-11-01
JPWO2023127869A1 (es) 2023-07-06

Similar Documents

Publication Publication Date Title
BR112019007682A2 (pt) produtos de xampu compactos estáveis com baixa viscosidade e agente redutor de viscosidade
CN104945847B (zh) 一种环氧树脂纳米微胶囊及其制备方法
BR0311206A (pt) Métodos para geração de gás e formação de espuma em um fluido de poço aquoso, e para gerar quimicamente gás e formar em uma solução ácida aquosa
AR016781A1 (es) Composicion detergente acuosa en gel de lavar ropa.
GT199800197A (es) Proceso para la sintesis de 1,3-dioles.
TWI372063B (en) Novel resorcinol derivatives for skin
CO2022012843A2 (es) Ácido sulfúrico modificado y sus usos
AR019317A1 (es) Composiciones cosmeticas que contienen un polimero anionico y un terpolimero acrilico y utilizacion de esas composiciones para el tratamiento de materias queratinicas
CO6241164A2 (es) Composiciones de limpieza que comprenden peroxido de hidrogeno
BR112019024811A2 (pt) composição de revestimento.
AR030859A1 (es) Proceso redox para preparar un polimero en emulsion que tiene un bajo contenido de monomero residual
CL2011000962A1 (es) Uso de composicion acuosa que comprende 0,01 a 20% de un compuesto de aluminio, 0,1 a 25% de un surfactante y un solvente porque sirve como un refrescante del aire o como un refrescante de telas.
BR0015385A (pt) Processo para a preparação de ácido fórmico
AR128119A1 (es) Método para producir n-alquilaminoácido y péptido que contiene n-alquilaminoácido
BR112022012185A2 (pt) Eletrólito aquoso para bateria de fluxo redox, uso de um eletrólito aquoso, bateria de fluxo redox e método para gerar eletricidade
BR112015007081A2 (pt) processo contínuo para preparar (met)acrilatos de misturas de álcool, e, uso de um diéster
CO2022002266A1 (es) Un proceso para la preparación de sulfentrazona con compatibilidad con mezcla en tanque
AR030977A1 (es) Proceso redox para preparar un polimero en emulsion que tiene un bajo contenido de formaldehido
BR112022006720A2 (pt) Processo para preparar fluoropolímeros e fluoroelastômeros na presença de um tensoativo contendo hidrocarboneto tipo sulfonato não fluorado do mesmo
CN108467707A (zh) 一种环保玻璃胶
KR960029306A (ko) α,β-불포화 에스테르의 정제방법
AR057075A1 (es) Procedimiento para la preparacion de cuero
BR112015030858A8 (pt) composição cosmética colorante, processo para a tintura das fibras queratínicas e dispositivo com compartimentos múltiplos
BR112019000892A2 (pt) vetiver
AR117785A1 (es) Composición de champú y método de uso

Legal Events

Date Code Title Description
FB Suspension of granting procedure