- +989118571200
Mohsen Toughani
Islamic Azad University Babol, Fishery, Graduate Student
Research Interests:
Leonurus japonicus is rich in bioactive compounds especially polysaccharide. Single factors test and response surface methodology were used to study the optimum conditions for ultrasonic - assisted extraction of polysaccharide from L.... more
Leonurus japonicus is rich in bioactive compounds especially polysaccharide. Single factors test and response surface methodology were used to study the optimum conditions for ultrasonic - assisted extraction of polysaccharide from L. japonicus, and its physiochemical and DPPH scavenging activities also were evaluated. The optimal conditions as underpinned by this paper is as follow: extraction temperature of 70 �C, extraction time of 50 min and extraction power of 210W. The polysaccharide of L. japonicus was shown to be a non-reducing sugar and to exhibit DPPH scavenging activity to an extent. The polysaccharide structures were studied using SEM, AFM, and FT-IR. It showed L. japonicus polysaccharide had been having more than one chains which were branched and entangled with each other. and existed a broad band wavelength of 2925.64, 1635.06, 1539.7, 1046.73, and 477.86 cm-1. The study indicated that L. japonicus may have a beneficial use to the medical and food industries.
Research Interests:
The global freshwater constraints, population growth, and pollution of surface and underground resources have created major concerns for water managers. One of the freshwater supply methods is the desalination of seawater. Saltwater... more
The global freshwater constraints, population growth, and pollution of surface and underground resources have created major concerns for water managers. One of the freshwater supply methods is the desalination of seawater. Saltwater desalination is a process by which solutes are separated from sea salt water. This process is one of the major sources of water today, especially in arid and semi-arid regions of the world, including the Persian Gulf and 40% of the world's salt desalination is in the Persian Gulf. Unfortunately, in most cases, untreated wastewater is discharged into the sea. This causes irreparable damage to the Persian Gulf ecosystem. In addition, the most significant adverse effects of desalination plants are high energy consumption, rising beach temperatures, beach occupation for installation for recreational and tourist uses, adverse effects on aquifers, air pollution, and oil leakage from facilities. In this review, the basis of the work of desalination plants,...
Research Interests:
Rivers are the most important sources of drinking water supply as well as agricultural activities. Among the rivers of Iran, the Haraz River, with a length of about 180 km in Mazandaran province, is one of the most important and most... more
Rivers are the most important sources of drinking water supply as well as agricultural activities. Among the rivers of Iran, the Haraz River, with a length of about 180 km in Mazandaran province, is one of the most important and most popular among them, which is one of the common activities in those cold-water fish farms. These farms, through the discharge of their effluent, may lead to environmental pollution and threaten the continuation of aquatic life in the river. Therefore, the purpose of this project was to study large communities of macrobenthic inoculants to evaluate the impact of contaminants on the biological conditions of this ecosystem in the months of October, November, December and in two Niyak areas (including 3 stations N1, N2, and N3 ) And Gazanak (including 3 stations G1, G2, and G3). The frequency of benthos samples from Baetide sp. (40.31%), Caenidae sp. (17.37%), Plecoptera sp. (9.04%), Hydropcyche sp. (16.03%), Chironomidae (13.80%) and Tubifex (3.45%) were co...
Research Interests:
To obtain the optimum fermentation medium and circumstances for extracellular lipase construction (as an important biocatalyst and promising industrial enzyme) by Aspergillus Niger, the fermentation conditions of Aspergillus Niger were... more
To obtain the optimum fermentation medium and circumstances for extracellular lipase construction (as an important biocatalyst and promising industrial enzyme) by Aspergillus Niger, the fermentation conditions of Aspergillus Niger were optimized by single factor and response surface design, the enzymatic properties of the crude enzyme were studied. The results displayed that the optimum fermentation medium was soluble starch 4%, (NH4)2SO4 0.1%, K2HPO4 0.1%, MgSO4·7H2O 0.05%, peptone 3%, olive oil 1.05% and initial pH 7. The optimal fermentation conditions were 30℃, the sample size was 26 mL/250 mL and the shaking speed was 213 r/min. The optimized lipase activity was 1.55 U/mL, which was 7.75 times of the pre-optimized lipase. It was found that when the pH value of lipase was 7.0, the activity of lipase reached its maximum value of 79.3±6.82%. When pH value was between 6.0 and 8.0, the activity of lipase could be kept above 60% and the stability was good. At the same time, through t...
Research Interests:
The environment of Iran is constantly changing in recent years and this issue cannot be ignored. Of the critical environmental crisis should refer to global warming, overcrowding, decreasing natural resources, garbage disposal, ozon layer... more
The environment of Iran is constantly changing in recent years and this issue cannot be ignored. Of the critical environmental crisis should refer to global warming, overcrowding, decreasing natural resources, garbage disposal, ozon layer destruction, deforestation, rainfalls, water pollution, public health issues, and genetic engineering. Men around the Iran are experiencing new and challenging environmental problems daily. Some of these problems are likely to affect the health of the ecosystem, but somehow they change the recent landscapes. The planet is on the verge of a massive environmental crisis. Environmental problems in Iran also make human beings vulnerable to natural disasters occurs currently and in the future, as well. So due to the growing problems of the environment in Iran, this is an emergency situation. Therefore, the current environmental situation greatly needs urgent consideations and many factors to be addressed. By increasing community awareness and concern ab...
Research Interests:
The heavy metals like zinc affect the aquatic and terrestrial environments in a number of ways which are currently well established. The practice of treating contaminated water and soil at low cost is continually gaining attention in... more
The heavy metals like zinc affect the aquatic and terrestrial environments in a number of ways which are currently well established. The practice of treating contaminated water and soil at low cost is continually gaining attention in developing countries. The phytoremediation technique is the most effective and low cost as compared to other technologies and also it is environment friendly. It is used to remove pollutants such as heavy metals from both water and soil. The experiment was based on two objectives i.e. to evaluate how marigold helps in phytoremediation of zinc from wastewater and secondly, to study the growth parameters under zinc metal stress. In this experiment, the marigold plant was used to remove zinc from synthetic wastewater at different concentrations (0, 100, 200, 300, and 400 µM). The experiment was done in different steps including plant collection, growth in a controlled environment, pre-analysis, post-analysis, drying, separation of parts, grinding digestion...
Research Interests:
The current investigation assessed the nickel and zinc contents of the soil, and the vegetables grown in wastewater irrigated areas. Atomic Absorption Spectrophotometer (AA-6300 Shimadzu Japan) assessed the metal profile of the samples.... more
The current investigation assessed the nickel and zinc contents of the soil, and the vegetables grown in wastewater irrigated areas. Atomic Absorption Spectrophotometer (AA-6300 Shimadzu Japan) assessed the metal profile of the samples. The mean concentrations of metals in soil samples varied from O.O85 to 1.611 mg/kg for Ni and O.453 ~ O.9O8 mg/kg for Zn. In vegetables, the maximum Ni concentration was observed in Capsicum baccatum consequent to wastewater irrigation, while its minimum concentrations were noticed in Capsicum frutescens after canal water irrigation. Sewage water irrigation resulted in the highest Zn contents in Solanum lycopersicum and the lowest Zn contents were noticed in Capsicum baccatum after canal water irrigation. The daily intake values of Ni and Zn were higher caused by sewage water irrigation as compared to the canal water irrigation in all tested vegetable samples. Health risk index (HRI) values for Ni and Zn accumulation in vegetables fell within the per...
Research Interests:
The current research explored the potential of microalgal species Chlorella vulgaris and Pretreatment to remediate plastic waste. It was concluded from the results that Pretreatment had a marked effect on the cracking and alteration of... more
The current research explored the potential of microalgal species Chlorella vulgaris and Pretreatment to remediate plastic waste. It was concluded from the results that Pretreatment had a marked effect on the cracking and alteration of plastic polymer, which helped to grow microbial species on the cracked surface as evident by Compound Microscopy (CM), Scanning Electron Microscopy (SEM), and Fourier Transformed Infrared Spectroscopy (FTIR) analysis. FTIR data also supported the notion that in the absence of any pretreatment, the microbial species were not able to mediate plastic biodegradation efficiently as the nature of functional groups was different in the presence and absence of Pretreatment. GCMS analysis revealed that the microbial specie could produce the biodegradation products which were likely to be found in the structure of PET, including alkanes ester, fatty acids, benzoic acid, and aromatics and the most toxic product of biodegradation is Bis (2-Ethyl hexyl phthalate),...
Research Interests:
Research Interests:
Abstract The objective of this review is to summarize recent progress and advances in the synthesis of hydroxymethyl-alcohols through the direct hydroxymethylation of unsaturated hydrocarbons using CO2 as the carbonyl source with... more
Abstract The objective of this review is to summarize recent progress and advances in the synthesis of hydroxymethyl-alcohols through the direct hydroxymethylation of unsaturated hydrocarbons using CO2 as the carbonyl source with insightful mechanistic discussions. Depending on the unsaturated substrates employed the paper is divided into three sections. The first section focuses exclusively on hydroxymethylation of alkenes. The second covers hydroxymethylation of allenes. The third section gives a brief overview of the hydroxymethylation of alkynes.
Research Interests:
Abstract In this study economic, reliable and environmentally friendly designing of a hybrid photovoltaic-biowaste-fuel cell (PV-Biowaste-FC) system based on hydrogen storage energy is presented using whale optimization algorithm (WOA)... more
Abstract In this study economic, reliable and environmentally friendly designing of a hybrid photovoltaic-biowaste-fuel cell (PV-Biowaste-FC) system based on hydrogen storage energy is presented using whale optimization algorithm (WOA) considering the availability of components for 20 years useful lifespan of the project. The WOA is a robust meta-heuristic method for solving optimization problems with high convergence speed and accuracy. The fuel cell system includes an electrolyzer, a hydrogen storage tank, and a fuel cell stack. The objective function is defined as minimization of total net present cost (TNPC) include investment, maintenance and repair and replacement cost and reliability constraint is considered as loss of power supply probability (LPSP). The optimization variables include the area occupied by photovoltaic (PV) panels, number of biowaste units, electrolyzers, hydrogen storage tanks, fuel cells, and inverters that are optimally determined by the WOA considering the TNPC and LPSP. To validate the WOA method in the PV-Biowaste-FC designing, its performance is compared with the particle swarm optimization (PSO) method. Simulations have been carried out for different scenarios including designing of Biowaste-FC and PV-Biowaste-FC system, evaluating the effect of PV, Biowaste and inverter availability and also effect of investment cost of FC on the system designing. Simulation results show that the hybrid system with the participation of all resources and hydrogen storage system as the PV-Biowaste-FC presents the minimum TNPC (2.820 M$) and the lower LPSP (0.0029) compared to the other combinations. Also, the cost of energy (COE) value for the hybrid PV-Biowaste-FC system is obtained at 0.5238 $/kWh. The proposed method for designing the hybrid system provides better performance than the PSO in achieving less TNPC and better reliability with higher convergence speed and accuracy. Further, the effects of the availability of PV units, biowaste, and inverter on the system designing are evaluated. According to the results, decreasing the availability of the components increases the TNPC and weakens the reliability indices.
Research Interests:
Colorectal cancer, is the growth of cancer cells in the part of the colon. Angiopeptin is one of the growth factors in the human body that is particularly effective in the regulatory process. In this research, the regulatory role and its... more
Colorectal cancer, is the growth of cancer cells in the part of the colon. Angiopeptin is one of the growth factors in the human body that is particularly effective in the regulatory process. In this research, the regulatory role and its mechanism of Angiopoietin-like protein 4 (ANGPTL4) in colorectal cancer (CRC) metastasis, has been studied. Protein expression of ANGPLT4 was analyzed by immunohistochemistry in tumor samples and adjacent normal specimens of 40 patients with CRC cancer of various phases. A gene knockout test was conducted, two effective siRNA of ANGPTL4, named siRNA1 and siRNA2, were constructed and transfected into two CRC cell lines SW480 and HT-29 to block the expression of ANGPTL4. QRT-PCR and western blotting were used to validate the knockdown efficiency of the mRNA and proteins. Based on the results, the protein expression of ANGPTL4 was increased in human CRC tissues with the development of CRC. Knockdown of ANGPTL4 by siRNA in SW480 and HT-29 cells in vitro...
Research Interests:
The problem of environmental pollution caused by the development and use of petroleum is increasingly obvious, which is a serious threat to human health. The use of microbial degradation to treat oil pollution is one of the... more
The problem of environmental pollution caused by the development and use of petroleum is increasingly obvious, which is a serious threat to human health. The use of microbial degradation to treat oil pollution is one of the environmentally effective, economical and practical methods.In order to explore the soil microbial diversity in the desert area of Northwest China, this paper analyzes the soil bacterial diversity of soil samples collected from different oil-contaminated areas in Yumen Oilfield for the oil pollution problem in the Yumen Oilfield in the northwest desert area, and selects the high efficiency through pure culture technology. Petroleum degradation bacteria, and research on the biological characteristics of degrading bacteria. The composition, abundance and diversity of bacterial communities in oil-contaminated soil in Yumen Oilfield were analyzed. The culturable bacteria in western oil-contaminated desert soil were separated by coating plate method. The bacterial mor...
Research Interests:
N-Aryl sulfonamides belong to a highly important class of organosulfur compounds which are found in a number of FDA-approved drugs such as dofetilide, dronedarone, ibutilide, sotalol, sulfadiazine, sulfamethizole, vemurafenib, and many... more
N-Aryl sulfonamides belong to a highly important class of organosulfur compounds which are found in a number of FDA-approved drugs such as dofetilide, dronedarone, ibutilide, sotalol, sulfadiazine, sulfamethizole, vemurafenib, and many more.
Research Interests:
Codonopsis genus is comprised of species that are perennial plants primarily distributed across all east, southeast, and Central Asia. The most famous species of Codonopsis are C. tangshen, C. lanceolate, and C. pilosula. The records... more
Codonopsis genus is comprised of species that are perennial plants primarily distributed across all east, southeast, and Central Asia. The most famous species of Codonopsis are C. tangshen, C. lanceolate, and C. pilosula. The records showed that they have a long story usage as traditional Chinese medicines, as they were alleged to be able to intensify the spleen and the lung as well as enriching blood and engendering liquid. Certain species have a culinary value in southern China and Southeast Asia, where they are considered as tea, wine, soup, plaster, and porridge. Codonopsis species were shown to be of great importance in medicine, due to their broad biological activity. Therefore, a clear understanding of their genetic diversity is needed. Adequate distinctions and descriptions of those species are necessary to preserve plant reservoir, investigations of genes associated with desirable traits, and understanding of evolutionary relationships. Subsequently, various molecular mark...
Research Interests:
Research Interests:
The extraction condition of crude polysaccharides from Codonopsis pilosula by hot water reflux method was studied and the results analyzed by kinetic model. Then, the extraction rate and maximum extraction temperature were determined.... more
The extraction condition of crude polysaccharides from Codonopsis pilosula by hot water reflux method was studied and the results analyzed by kinetic model. Then, the extraction rate and maximum extraction temperature were determined. furthermore, the thermal and pH stability and the rheological properties of the crude polysaccharide were also studied. crude Codonopsis pilosula polysaccharide (CCPP) under different conditions was extracted by hot water reflux method, the content was determined by phenol-sulfuric acid and DNS method, and the kinetic model of the extraction process was established. The viscosity was determined under different solute concentration, salt concentration, rotation speed, pH, and temperature. The thermal stability and pH stability were determined; the protein content and sulfate ion content were determined by the coomassie brilliant blue method and barium sulfate turbidimetry method, respectively. The yield of CCPP by the hot water reflux method was 25.72%....
Research Interests:
Abstract In this paper, a circuit-based model of proton exchange membrane fuel cell (PEMFC) is developed for optimal selection of the model parameters. The optimization is based on using an improved version of Monarch Butterfly... more
Abstract In this paper, a circuit-based model of proton exchange membrane fuel cell (PEMFC) is developed for optimal selection of the model parameters. The optimization is based on using an improved version of Monarch Butterfly Optimization (IMBO) algorithm for minimizing the Integral Time Absolute Error between the measured output voltage and the output voltage of the achieved model. For validation of the proposed method, two different case studies including 6 kW NedSstack PS6 and 2 kW Nexa FC PEMFC stacks have been employed and the results have been compared with the experimental data and some well-known metaheuristics including Chaotic Grasshopper Optimization Algorithm (CGOA), Grass Fibrous Root Optimization Algorithm (GRA), and basic Monarch Butterfly Optimization (MBO) to indicate the superiority of the proposed method against the compared methods. Final results show a satisfying agreement between the proposed IMBO and the experimental data.
Research Interests:
The current investigation assessed the nickel and zinc contents of the soil, and the vegetables grown in wastewater irrigated areas. Atomic Absorption Spectrophotometer (AA-6300 Shimadzu Japan) assessed the metal profile of the samples.... more
The current investigation assessed the nickel and zinc contents of the soil, and the vegetables grown in wastewater irrigated areas. Atomic Absorption Spectrophotometer (AA-6300 Shimadzu Japan) assessed the metal profile of the samples. The mean concentrations of metals in soil samples varied from O.O85 to 1.611 mg/kg for Ni and O.453 ~ O.9O8 mg/kg for Zn. In vegetables, the maximum Ni concentration was observed in Capsicum baccatum consequent to wastewater irrigation, while its minimum concentrations were noticed in Capsicum frutescens after canal water irrigation. Sewage water irrigation resulted in the highest Zn contents in Solanum lycopersicum and the lowest Zn contents were noticed in Capsicum baccatum after canal water irrigation. The daily intake values of Ni and Zn were higher caused by sewage water irrigation as compared to the canal water irrigation in all tested vegetable samples. Health risk index (HRI) values for Ni and Zn accumulation in vegetables fell within the permissible limit in Pakistan and these were regarded as appropriate for human intake.
Research Interests:
Leonurus japonicus is rich in bioactive compounds especially polysaccharide. Single factors test and response surface methodology were used to study the optimum conditions for ultrasonic-assisted extraction of polysaccharide from L.... more
Leonurus japonicus is rich in bioactive compounds especially polysaccharide. Single factors test and response surface methodology were used to study the optimum conditions for ultrasonic-assisted extraction of polysaccharide from L. japonicus, and its physiochemical and DPPH scavenging activities also were evaluated. The optimal conditions as underpinned by this paper is as follow: extraction temperature of 70 °C, extraction time of 50 min and extraction power of 210W. The polysaccharide of L. japonicus was shown to be a non-reducing sugar and to exhibit DPPH scavenging activity to an extent. The polysaccharide structures were studied using SEM, AFM, and FT-IR. It showed L. japonicus polysaccharide had been having more than one chains which were branched and entangled with each other. and existed a broad band wavelength of 2925.64, 1635.06, 1539.7, 1046.73, and 477.86 cm-1. The study indicated that L. japonicus may have a beneficial use to the medical and food industries.
Research Interests:
The extraction condition of crude polysaccharides from Codonopsis pilosula by hot water reflux method was studied and the results analyzed by kinetic model. Then, the extraction rate and maximum extraction temperature were determined.... more
The extraction condition of crude polysaccharides from Codonopsis pilosula by hot water reflux method was studied and the results analyzed by kinetic model. Then, the extraction rate and maximum extraction temperature were determined. furthermore, the thermal and pH stability and the rheological properties of the crude polysaccharide were also studied. crude Codonopsis pilosula polysaccharide (CCPP) under different conditions was extracted by hot water reflux method, the content was determined by phenol-sulfuric acid and DNS method, and the kinetic model of the extraction process was established. The viscosity was determined under different solute concentration, salt concentration, rotation speed, pH, and temperature. The thermal stability and pH stability were determined; the protein content and sulfate ion content were determined by the coomassie brilliant blue method and barium sulfate turbidimetry method, respectively. The yield of CCPP by the hot water reflux method was 25.72%. At 50 o C, the maximum extraction concentration, the rate constant and the linear relationship between the rate constant and the time were obtained at different ratios of material to liquid. The extraction process of this experiment coincided with Fick's second law, R2 was greater than 0.88 and with the increase of extraction time, the dissolution rate increased, but with the increase of the ratio of material to liquid, the dissolution rate was decreased. CCPP showed a loss of polysaccharide fluidity as temperature increased and was affected by pH change. The apparent viscosity was affected by a change in solute concentration, temperature, pH, rotation speed and salt and sucrose concentrations.
Research Interests:
The problem of environmental pollution caused by the development and use of petroleum is increasingly obvious, which is a serious threat to human health. The use of microbial degradation to treat oil pollution is one of the... more
The problem of environmental pollution caused by the development and use of petroleum is increasingly obvious, which is a serious threat to human health. The use of microbial degradation to treat oil pollution is one of the environmentally effective, economical and practical methods.In order to explore the soil microbial diversity in the desert area of Northwest China, this paper analyzes the soil bacterial diversity of soil samples collected from different oil-contaminated areas in Yumen Oilfield for the oil pollution problem in the Yumen Oilfield in the northwest desert area, and selects the high efficiency through pure culture technology. Petroleum degradation bacteria, and research on the biological characteristics of degrading bacteria. The composition, abundance and diversity of bacterial communities in oil-contaminated soil in Yumen Oilfield were analyzed. The culturable bacteria in western oil-contaminated desert soil were separated by coating plate method. The bacterial morphology and 16S rRNA gene system development analysis were studied. The structure and diversity of bacterial community could be cultured, and the oil utilization and degradation ability of the strain could be analyzed. The microbial diversity of Yumen oil-contaminated desert soil was analyzed by Illumina Miseq high-throughput sequencing. Through research, it is found that there are abundant bacterial groups in the oil-contaminated desert soil, and there are obvious diversity. The genetic material in the variable regions of the six soil samples detected a total of 3943 0TU at 97% similarity level, and obtained the soil microbial community. Doors, 48 classes, 78 orders, 179 families and 471 genera, including most common high-efficiency petroleum-degrading bacteria. Petroleum hydrocarbon pollution can change the microbial diversity and community structure of the original soil. The size of microbial diversity in the six soil samples is B2>A1>B1>A2>C1>C2, the diversity of B2 is the highest, the diversity of C2 is the lowest, and the microbial diversity differed greatly between groups, and there was no difference in the group. Among the dominant bacteria isolated from contaminated soil, 8 strains of oil have a degradation rate of more than 30%, including the species of the genus Rhodococcus and Pseudomonas. Soil desertification in western China has a great impact on the local ecological environment. Studying the microbial diversity of desert soils and separating high-efficiency petroleum-degrading strains is of great significance for strengthening the ecological restoration of oil-contaminated environment in desert areas.
Research Interests:
Aim of present study was to investigate the interaction of coomassie brilliant blue G-250 (CBBG-250) with bovine serum albumin (BSA) by the multispectroscopic methods. Fluorescence-data showed that the complex of BSA-CBBG-250 forming made... more
Aim of present study was to investigate the interaction of coomassie brilliant blue G-250 (CBBG-250) with bovine serum albumin (BSA) by the multispectroscopic methods. Fluorescence-data showed that the complex of BSA-CBBG-250 forming made the intrinsic fluorescence quenching of BSA by CBBG-250 interaction. BSA also could interact with CBBG-250 and the CBBG-BSA complexes formed in a molar ratio of 1:1. UV-Vis results displayed that the apparent binding (association) constant K a of CBBG-250 with BSA was 5.03 × 10 4 (298 K), 3.04 × 10 4 (303 K), 2.84 × 10 4 (308 K) and 1.99 × 10 4 (313 K) L mol −1 at different temperatures, respectively. The enthalpy change (△H) and entropy change (△S) were respectively calculated to be − 45.32 kJ mol −1 and − 139.18 J mol −1 K −1 , indicating that the hydrogen bonds and Van der Waals forces played dominant roles in the interaction. The results showed that the diphenylamine structure and amino acid residues in the Coomassie Brilliant Blue G-250 had a strong Van der Waals force. The phenyl sulphonic acid group undergoes electrostatic interactions and hydrogen bond interactions with basic amino acids; the compound Coomassie Brilliant Blue G-250 can form a stable complex with BSA.
Research Interests:
N-Aryl sulfonamides belong to a highly important class of organosulfur compounds which are found in a number of FDA-approved drugs such as dofetilide, dronedarone, ibutilide, sotalol, sulfadiazine, sulfamethizole, vemurafenib, and many... more
N-Aryl sulfonamides belong to a highly important class of organosulfur compounds which are found in a number of FDA-approved drugs such as dofetilide, dronedarone, ibutilide, sotalol, sulfadiazine, sulfamethizole, vemurafenib, and many more. There is therefore continuing interest in the development of novel and convenient protocols for the preparation of these pharmaceutically important compounds. Recently, direct sulfonamidation of (hetero)aromatic C-H bonds with easily available sulfonyl azides has emerged as an attractive and powerful strategy to access N-(hetero)aryl sulfonamides where non-toxic nitrogen gas forms as the sole by-product. This review highlights recent advances and developments (2012-2020) in this fast growing research area with emphasis on the mechanistic features of the reactions.
Research Interests:
The heavy metals like zinc affect adversely the aquatic and terrestrial environments.Phytoremediation technique is most effective, low cost and environmental friendly method used to remove pollutants such as heavy metals from... more
The heavy metals like zinc affect adversely the aquatic and terrestrial environments.Phytoremediation technique is most effective, low cost and environmental friendly method used to remove pollutants such as heavy metals from both water and soil. The present study aims to evaluate marigold effect in phytoremediation of zinc from waste water and investigate the growth parameters under zinc metal stress. To this aim, marigold plant was used to remove zinc from synthetic waste water at different concentrations (0, 100,200,300,and 400 μM). The experiment was conducted for 15 days in different steps including plant collection, growth in controlled environment, pre-analysis, post-analysis, drying, separation of parts, grinding digestion, filtration and metal detection byusing atomic absorption spectrophotometer. Zinc accumulation was checked by detection of zinc metal in roots, shots, and leaves of plants. According to results, in roots, stem and in leaves zinc found in range of (5.67 to 17.37); (4.81 to 9.33) and (3.3 to 8.37), respectively. It could be concluded that this plant have zinc accumulation capacity and it is useful to treat zinc contaminated site.
Research Interests:
The current research explored the potential of microalgal species Chlorella vulgaris and Pretreatment to remediate plastic waste. It was concluded from the results that Pretreatment had a marked effect on the cracking and alteration of... more
The current research explored the potential of microalgal species Chlorella vulgaris and Pretreatment to remediate plastic waste. It was concluded from the results that Pretreatment had a marked effect on the cracking and alteration of plastic polymer, which helped to grow microbial species on the cracked surface as evident by Compound Microscopy (CM), Scanning Electron Microscopy (SEM), and Fourier Transformed Infrared Spectroscopy (FTIR) analysis. FTIR data also supported the notion that in the absence of any pretreatment, the microbial species were not able to mediate plastic biodegradation efficiently as the nature of functional groups was different in the presence and absence of Pretreatment. GCMS analysis revealed that the microbial specie could produce the biodegradation products which were likely to be found in the structure of PET, including alkanes ester, fatty acids, benzoic acid, and aromatics and the most toxic product of biodegradation is Bis (2-Ethyl hexyl phthalate), which is the biodegradation product of toxic ingredient of plastics that is phthalic acid.
Research Interests:
Synthesis of carboxylic acids and derivatives using CO2 as a sustainable and renewable source of carboxyl is most probably the area that has experienced the most growth in the field of CO2 conversion reactions. Over the years, an enormous... more
Synthesis of carboxylic acids and derivatives using CO2 as a sustainable and renewable source of carboxyl is most
probably the area that has experienced the most growth in the field of CO2 conversion reactions. Over the years,
an enormous effort has been put forth by scientists toward exploration of the utility of various nucleophilic
partners in the coupling with electrophilic CO2. Organosilicon compounds are one of the latest nucleophilic
reagents that was joined to the story of carboxylation reactions with CO2 and has been the subject of a number of
studies in recent years. The aim of this review is to present an overview of the recent advances and achievements
of the desilylative carboxylation of organosilicon compounds, with particular emphasis on the mechanistic aspects
of the reactions.
probably the area that has experienced the most growth in the field of CO2 conversion reactions. Over the years,
an enormous effort has been put forth by scientists toward exploration of the utility of various nucleophilic
partners in the coupling with electrophilic CO2. Organosilicon compounds are one of the latest nucleophilic
reagents that was joined to the story of carboxylation reactions with CO2 and has been the subject of a number of
studies in recent years. The aim of this review is to present an overview of the recent advances and achievements
of the desilylative carboxylation of organosilicon compounds, with particular emphasis on the mechanistic aspects
of the reactions.
Research Interests:
Without slight doubt synthesis of carboxylic acids and their derivatives through the carboxylation reactions of organometallic compounds using CO2 as the raw material are one of the most attractive and hot research topics in the field of... more
Without slight doubt synthesis of carboxylic acids and their derivatives through the carboxylation reactions of
organometallic compounds using CO2 as the raw material are one of the most attractive and hot research topics
in the field of CO2 utilization. Therefore, broadening the scope of nucleophilic reagents for this appealing page of
carboxylic acids synthesis is always interesting. Over the past few decades, organoboron compounds have
aroused great interest in the organic chemistry community as promising organometallic reagents owing to their
high stability, reactivity, safety, and easy accessibility. Not surprisingly, these compounds have recently found
application in the area of CO2-fixation reactions. This review describes the achievements that have been reported
on this fast-growing research arena.
organometallic compounds using CO2 as the raw material are one of the most attractive and hot research topics
in the field of CO2 utilization. Therefore, broadening the scope of nucleophilic reagents for this appealing page of
carboxylic acids synthesis is always interesting. Over the past few decades, organoboron compounds have
aroused great interest in the organic chemistry community as promising organometallic reagents owing to their
high stability, reactivity, safety, and easy accessibility. Not surprisingly, these compounds have recently found
application in the area of CO2-fixation reactions. This review describes the achievements that have been reported
on this fast-growing research arena.
Research Interests:
A new technique proposed for optimal selection of PEMFC parameters The method is based on a new model of Coyote Optimization Algorithm The achieved results showed a good confirmation by the experimental data Available online xxx Keywords:... more
A new technique proposed for optimal selection of PEMFC parameters The method is based on a new model of Coyote Optimization Algorithm The achieved results showed a good confirmation by the experimental data Available online xxx Keywords: Parameter identification Proton exchange membrane fuel Monarch Butterfly Optimization Improved a b s t r a c t In this paper, a circuit-based model of proton exchange membrane fuel cell (PEMFC) is developed for optimal selection of the model parameters. The optimization is based on using an improved version of Monarch Butterfly Optimization (IMBO) algorithm for minimizing the Integral Time Absolute Error between the measured output voltage and the output voltage of the achieved model. For validation of the proposed method, two different case studies including 6 kW NedSstack PS6 and 2 kW Nexa FC PEMFC stacks have been employed and the results have been compared with the experimental data and some well-known metaheuristics including Chaotic Grasshopper Optimization Algorithm (CGOA), Grass Fibrous Root Optimization Algorithm (GRA), and basic Monarch Butterfly Optimization (MBO) to indicate the superiority of the proposed method against the compared methods. Final results show a satisfying agreement between the proposed IMBO and the experimental data.
Research Interests:
Codonopsis genus is comprised of species that are perennial plants primarily distributed across all east, southeast, and Central Asia. The most famous species of Codonopsis are C. tangshen, C. lanceolate, and C. pilosula. The records... more
Codonopsis genus is comprised of species that are perennial plants primarily distributed across all east, southeast, and Central Asia. The most famous species of Codonopsis are C. tangshen, C. lanceolate, and C. pilosula. The records showed that they have a long story usage as traditional Chinese medicines, as they were alleged to be able to intensify the spleen and the lung as well as enriching blood and engendering liquid. Certain species have a culinary value in southern China and Southeast Asia, where they are considered as tea, wine, soup, plaster, and porridge. Codonopsis species were shown to be of great importance in medicine, due to their broad biological activity. Therefore, a clear understanding of their genetic diversity is needed. Adequate distinctions and descriptions of those species are necessary to preserve plant reservoir, investigations of genes associated with desirable traits, and understanding of evolutionary relationships. Subsequently, various molecular marker techniques such as Random Amplified Polymorphic DNA (RAPD), Amplified Fragment Length Polymorphism (AFLP), Simple Sequence Repeats (SSR), and Inter Simple Sequence Repeat (ISSR), Single Nucleotide Polymorphism (SNP), internal transcribed spacer (ITS), and Sequence-Characterized Amplified Region (SCAR) have been improved to provide detailed informations about genomes, that historically were not possible to obtain based on only phenotypic methods. This review represents the usage of DNA molecular markers for molecular diversity analysis of medically important species belonging to the genus Codonopsis.
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Colorectal cancer, is the growth of cancer cells in the part of the colon. Angiopeptin is one of the growth factors in the human body that is particularly effective in the regulatory process. In this research, the regulatory role and its... more
Colorectal cancer, is the growth of cancer cells in the part of the colon. Angiopeptin is one of the growth factors in the human body that is particularly effective in the regulatory process. In this research, the regulatory role and its mechanism of Angiopoietin-like protein 4 (ANGPTL4) in colorectal cancer (CRC) metastasis, has been studied. Protein expression of ANGPLT4 was analyzed by immunohistochemistry in tumor samples and adjacent normal specimens of 40 patients with CRC cancer of various phases. A gene knockout test was conducted, two effective siRNA of ANGPTL4, named siRNA1 and siRNA2, were constructed and transfected into two CRC cell lines SW480 and HT-29 to block the expression of ANGPTL4. QRT-PCR and western blotting were used to validate the knockdown efficiency of the mRNA and proteins. Based on the results, the protein expression of ANGPTL4 was increased in human CRC tissues with the development of CRC. Knockdown of ANGPTL4 by siRNA in SW480 and HT-29 cells in vitro inhibited cell proliferation, promoted cell apoptosis, and suppressed the ability of cell migration and invasion. Besides, the sensitivity of CRC cells to Cisplatin was increased in the low ANGPTL4 expression group. ANGPTL4 might be a new potential therapeutic target for patients with CRC.
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The present study aims to investigate large communities of macrobenthic inoculants to evaluate the impact of contaminants on the biological conditions of Haraz River ecosystem. For this purpose, two Niyak and Gazanak stations were studied... more
The present study aims to investigate large communities of macrobenthic inoculants to evaluate the impact of contaminants on the biological conditions of Haraz River ecosystem. For this purpose, two Niyak and Gazanak stations were studied during October to December. The frequency of benthos samples from Baetis sp. (40.31%), Caenis sp. (17.37%), Scopura sp. (9.04%), Hydropcyche sp. (16.03%), Chironominae sp.(13.80%) and Tubifex sp. (3.45%) were counted. In order to investigate the relationships between quantitative traits, Pearson correlation coefficient analysis was performed using SAS software version 4.9 and mean comparison using Duncan's multiple range Test. Error level for all attributes was considered 0.05. Results show an increase in the relative pollution of station 1 (Niyak) towards station 6 (Gazanak). On this basis, the highest and lowest rate of pollution was observed at G2 and N1 stations, respectively. Based on the Pearson correlation coefficient, benthos of the Choronomidae and Tubifex family, which indicate water pollution, showed direct relationship with all water qualitative factors, such as BOD, COD, DO, EC, Temp, pH, nitrate, phosphate, carbonate, ammonium, TDS and chlorine, except DO. While, other benthoses that are usually indicators of fresh water, are related to all factors, except DO. Therefore, the macrobenthic pollution of the Haraz River in the studied area, does not have environmental concerns.
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The environment of Iran is constantly changing in recent years and this issue cannot be ignored. Of the critical environmental crisis should refer to global warming, overcrowding, decreasing natural resources, garbage disposal, ozon layer... more
The environment of Iran is constantly changing in recent years and this issue cannot be ignored. Of the critical environmental crisis should refer to global warming, overcrowding, decreasing natural resources, garbage disposal, ozon layer destruction, deforestation, rainfalls, water pollution, public health issues, and genetic engineering. Men around the Iran are experiencing new and challenging environmental problems daily. Some of these problems are likely to affect the health of the ecosystem, but somehow they change the recent landscapes. The planet is on the verge of a massive environmental crisis. Environmental problems in Iran also make human beings vulnerable to natural disasters occurs currently and in the future, as well. So due to the growing problems of the environment in Iran, this is an emergency situation. Therefore, the current environmental situation greatly needs urgent considerations and many factors to be addressed. By increasing community awareness and concern about issues, it can help to create a more friendly environment conscious for survival.