Magnesium sulfate is a mineral used as an antacid, anticonvulsant, and laxative. It works by increasing the osmotic gradient in the intestines to cause water retention and bowel evacuation. It also acts as an anticonvulsant by depressing the central nervous system. Nurses should assess for side effects like nausea and hypotension when administering magnesium sulfate intravenously and monitor renal function and bowel activity. They educate patients on proper use and monitor their response.
Magnesium sulfate is a mineral used as an antacid, anticonvulsant, and laxative. It works by increasing the osmotic gradient in the intestines to cause water retention and bowel evacuation. It also acts as an anticonvulsant by depressing the central nervous system. Nurses should assess for side effects like nausea and hypotension when administering magnesium sulfate intravenously and monitor renal function and bowel activity. They educate patients on proper use and monitor their response.
Magnesium sulfate is a mineral used as an antacid, anticonvulsant, and laxative. It works by increasing the osmotic gradient in the intestines to cause water retention and bowel evacuation. It also acts as an anticonvulsant by depressing the central nervous system. Nurses should assess for side effects like nausea and hypotension when administering magnesium sulfate intravenously and monitor renal function and bowel activity. They educate patients on proper use and monitor their response.
Magnesium sulfate is a mineral used as an antacid, anticonvulsant, and laxative. It works by increasing the osmotic gradient in the intestines to cause water retention and bowel evacuation. It also acts as an anticonvulsant by depressing the central nervous system. Nurses should assess for side effects like nausea and hypotension when administering magnesium sulfate intravenously and monitor renal function and bowel activity. They educate patients on proper use and monitor their response.
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Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects Nursing Responsibilities
Generic Name: Pharmacologic Class: - In laxative action, it General Indications: - Hypersensitivity - CNS (with I.V. use): Before: Magnesium Sulfate Mineral increases osmotic gradient - Used for - Myocardial damage confusion, decreased - Check the doctor’s order in small intestine, which treatment/prevention of - Diabetic coma reflexes, dizziness, - Assess patients sensitivity to Trade/Brand Name: draws water into intestines hypomagnesemia; - Heart block syncope, sedation, magnesium - Epsom Salt, magnesium and causes distention. These prevention and treatment - Hypermagnesemia hypothermia, paralysis - Assess GI pain (duration, sulfate injection effects stimulate peristalsis of seizures in severe - Hypercalcemia - CV (with I.V. use): location, quality, time of and bowel evacuation. preeclampsia or - Administration during 2 hypotension, occurrence, relief with food, Route: Therapeutic Class: - In electrolyte action, it is eclampsia; pediatric hours preceding delivery arrhythmias, circulatory causative/exacerbative factors). P.O., Intramuscular, Antacid, anticonvulsant, primarily found in acute nephritis, treatment for mothers with toxemia of collapse - Assess for weight loss, nausea, Intravenous electrolyte, laxative. intracellular fluids, essential of arrhythmias due to pregnancy - GI: nausea, vomiting, vomiting, and history of recent for enzyme activity, nerve hypomagnesemia cramps, flatulence, abdominal surgery. Form: conduction, muscle (ventricular fibrillation, anorexia - Assess renal function, serum Oral, Parenteral, Topical contraction. Maintains and ventricular tachycardia, - Metabolic: magnesium levels. restores magnesium levels. or torsades de points Drug Interaction/s: hypermagnesemia, - Perform hand hygiene and Maximum dose: - In antacid action, reacts - Aminoquinolones, hypocalcemia prepare the medication. 30 to 40g MgSO4 with hydrochloric acid in nitrofurantoin, - Musculoskeletal (with - Educate the patient about the stomach to form water and penicillamine, tetracyclines: I.V. use): muscle drug, its benefits and risks. Minimum dose: increase gastric pH levels. decreased absorption of weakness, flaccidity 4g MgSO4 - In anticonvulsant action, these drugs (with oral - Respiratory: respiratory depresses CNS and blocks magnesium) paralysis During: Availability: transmission of peripheral - CNS depressants: additive - Skin: diaphoresis - Identify the patient - Granules (for oral use): neuromuscular impulses, effects - Other: allergic reaction, - Inspect the parenteral drug 120 g, 4 lb producing seizure control. - Digoxin: heart block, injection site reaction, product for particulate matter - Infusion Solution: 10 Pharmacokinetics: conduction changes (with laxative dependence and discoloration. mg/ml, 20 mg/ml, 40 Absorption - Following I.V. use) (with repeated or - administer only the prescribed mg/ml, 80 mg/ml. administration, 30-50% of - Enteric-coated drugs: prolonged use) dose for the patient - Injection Solution: 125 the dose is absorbed from faster dissolution of these - inform the patient about the mg/ml, 500 mg/ml. the small intestine. drugs possible side effects. Distribution - Crosses the - Neuromuscular blockers: Content: placenta and small amounts increased effects of these Magnesium, Sulfur, enter the breastmilk. drugs (with I.V. use) After: Oxygen Protein-binding: 25-30% - document the drug Excretion - Via urine administered (absorbed fraction); Via - monitor patient’s response to faeces (unabsorbed drug, as well as the adverse fraction). effects - discontinue drugs if adverse effects occur - evaluate effectiveness of Pregnancy Category: D teaching plan - Assess for relief of gastric distress. - Monitor renal function (esp. if dosing is long term or frequent).
