MAGNESIUM SULFATE

NAME AND DOSE,

Generic name: Mild: 1 g Magnesium is Used for  Contraindicated to pts CNS: weakness, BEFORE ADMINISTRATION
Magnesium Sulfate intramuscularly the second most immediate control with allergy to  Consumer information use and
dizziness, fainting, disclaimer.
(IM) every 6 plentiful cation of life-threatening magnesium products;
Brand name: hours for 4 of the convulsions in the heart block, myocardial sweating (PO)  Use magnesium sulfate during
Concept Ob, Suprep doses intracellular treatment of pregnancy only in LIFE-
damage, abdominal pain,
THREATENING emergencies
Bowel Prep Kit, fluids. It is severe toxemias nausea, vomiting, or CV: palpitations when no safer drug available.
Tandem Plus, Tis-U- Severe: 5 g essential for the (pre-eclampsia other symptoms of Positive evidence of human fetal
sol intravenously activity of many and eclampsia) of appendicitis; acute GI: Excessive bowel risk.
(IV) over 3 enzyme systems pregnancy and in surgical abdomen, fecal  Assessment
Classification: hours and plays an the treatment of activity, perianal
impaction, intestinal and  History: Hypersensitivity
 Therapeutic: important role acute nephritis in biliary duct obstruction, irritations to drug
Antidysrhythmics, Maintenance: with regard to children. Also Hepatitis  Check expiration date.
V 30-60 neurochemical indicated for  Do not give during 2-hr Metabolic:  Do not give magnesium sulfate to
mg/kg/day IV transmission and replacement preceding delivery patients with abdominal pain,
hypermagnesemia and nausea and vomiting
 Pharmacologic: muscular therapy in because of the risk of toxicity in patients with
Electrolytes excitability. magnesium magnesium toxicity to
Magnesium deficiency, the neonate. renal failure.
DURING ADMINISTRATION
sulfate reduces especially in  Discontinue if hypersensitivity
striated muscle acute occurs.
contractions and hypomagnesemia  Monitor serum magnesium levels.
blocks accompanied by  Monitor knee-jerk reflex
peripheral signs of tetany  Monitor bowel function, if diarrhea
neuromuscular similar to those of and cramping occur, discontinue
transmission by hypocalcemia. usage.
reducing Also used in
acetylcholine uterine tetany as a
release at the myometriat AFTER ADMINISTRATION
myoneural relaxant.  Discontinue drug and notify
junction. physician if S&S of
Additionally, hypersensitivity occurs.
Magnesium
inhibits Ca2+
influx through
dihydropyridine
-sensitive,
voltage-
dependent
channels. This
accounts for
much of its
relaxant action
on vascular
smooth muscle.