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MR-OPV Immunization Anaphylaxis Protocol

This advisory provides guidance for managing acute anaphylaxis as an adverse event following immunization during the Measles Rubella – Oral Polio Vaccine Supplemental Immunization Activity. It recommends administering adrenaline (epinephrine) intramuscularly as the initial treatment for anaphylaxis. The dosage for children ages 1 to under 2 years old is 0.1 mL. Vaccination teams must have emergency kits with adrenaline and be trained to recognize signs of anaphylaxis and properly administer adrenaline. Supervisors must ensure teams follow these protocols.

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789 views1 page

MR-OPV Immunization Anaphylaxis Protocol

This advisory provides guidance for managing acute anaphylaxis as an adverse event following immunization during the Measles Rubella – Oral Polio Vaccine Supplemental Immunization Activity. It recommends administering adrenaline (epinephrine) intramuscularly as the initial treatment for anaphylaxis. The dosage for children ages 1 to under 2 years old is 0.1 mL. Vaccination teams must have emergency kits with adrenaline and be trained to recognize signs of anaphylaxis and properly administer adrenaline. Supervisors must ensure teams follow these protocols.

Uploaded by

D Alfz EinsTein JD
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Republic of the Philippines

Department of Health
OFFICE OF THE SECRETARY

27 October 2020

ADVISORY NO. 3 with AMENDMENT


Measles Rubella – Oral Polio Vaccine Supplemental Immunization Activity
(MR - OPV SIA)

This advisory is issued to guide all Centers for Health Development and LGUs
implementing the Measles Rubella – Oral Polio Vaccine Supplemental Immunization
Activity (MR-OPV SIA) regarding the recommended initial management of acute
anaphylaxis as a life-threatening adverse event following immunization (AEFI). Below is
the Adrenaline (Epinephrine) administration protocol stipulated in the DOH Manual of
Procedure for Surveillance and Response to AEFI (2014). Included is the dosage for
children ages 1 to < 2 years old.

Adrenaline in the initial management of Acute Anaphylaxis


Drug, site and route Frequency of Dose Dose
of administration administration (adult) (child)

Adrenaline Repeat in every 5-15 min 0.5 mL According to age;


(epinephrine) 1:000, as needed until there is
IM to the midpoint resolution of the < 1-year-old: 0.05 mL
of the anterolateral anaphylaxis.
aspect of the middle 1 to < 2 years old: 0.1 mL
third of the thigh Note: Persisting or
immediately worsening cough 2 to < 6 years old: 0.15 mL
associated with
pulmonary edema is an 6 to 12 years old: 0.3 mL
important sign of
adrenaline overdose and Children > 12 years old: 0.5 mL
toxicity.

Furthermore, all supervisors must ensure that vaccination teams have an on-hand
emergency kit with adrenaline, and vaccinators must be familiar in recognizing signs of
anaphylaxis and the proper dosage and administration techniques to manage such
emergencies.

All other technicalities on managing AEFIs can be referred to in the


abovementioned manual Annex E. Thank you.

MYRNA C. CABOTAJE, MD, MPH, CESO III


Undersecretary of Health
Public Health Services Team

Building 1, San Lazaro Compound, Rizal Avenue, Sta. Cruz, 1003 Manila ● Trunk Line 651-7800 local 1108, 1111, 1112, 1113
Direct Line: 711-9502; 711-9503 Fax: 743-1829 ● URL: http://www.doh.gov.ph; e-mail: ftduque@doh.gov.ph

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