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Pharmaceutical Calculation

1. The concentration of the resulting solution from mixing 30gm of 1% hydrocortisone and 40gm of 2.5% hydrocortisone in a total solution of 70gm is 1.857%. 2. The molarity of a solution made by dissolving 17.52g of NaCl in exactly 2000ml of solution is 0.153M. 3. Fifty micrograms equals 0.00005 grams.

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0% found this document useful (0 votes)
1K views7 pages

Pharmaceutical Calculation

1. The concentration of the resulting solution from mixing 30gm of 1% hydrocortisone and 40gm of 2.5% hydrocortisone in a total solution of 70gm is 1.857%. 2. The molarity of a solution made by dissolving 17.52g of NaCl in exactly 2000ml of solution is 0.153M. 3. Fifty micrograms equals 0.00005 grams.

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RPh Farhatain
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© © All Rights Reserved
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1-30gm of 1% hydrocortisone mixed with 40 gm 2.

5%
hydrocortisonen what is the concentration of the resulting
solution?
\ma) 3% b) 1.85%
c)10% d) none of the above
30gm--------------1% ------------=0.3gm
40gm--------------2.5% --------------=1gm
So, 70gm-------------X%--------------=1.3
So, the con. Result =1.3/70=1.857%
2- A solution is made by dissolving 17.52 g of NaCl exactly 2000 ml.
What is the molarity of this solution?
a- 3.33 b- 0.15
c- 1.60 d-3.00 x 10 -4 e-1.6x10 -4
Molarity=mole/volume (L)
1 Mole=molecular weight of subs. In 1 grams
No of Moles = wt / Mwt
So, molecular weight of NACL=23+34=57
So, Mole=17.52/57=0.307
So, Morality=0.307/2=0.153

HCl= 36.4
NH4Cl= 53.5
NaCl= 58.5
Kcl= 74.5
MgCl2= 95.2
CaCl2= 111
Na=23,5 Mg 24.3 Cl= 35.4 K= 39.1
3- Fifty micrograms equals:
a-50000 ( nanogrames )? b- 0.05 ( milligrams )?
c- 0.0005 g
d- a and b
e- a and c

mc g : 1000 nano g milli g : 1000 mc g g : 1000 mg g : 1000000 mc g


4-HOW can prepare 100 ml of 12% MgCl by taking?
a-12ml of MGCL dissolve in 100 ml water
b-12 gm of MGCL dissolve in 100 ml water
c-12ml of MGCL dissolve in 1000 ml water
d-90.5 ml of MGCL dissolve in 100 ml water
e-.95 ml of MGCL dissolve in 100 ml water

w / v = g / ml ex ; 4% w/v means 4 gm in 100 ml

5- prep. contin coal tar 30 part


petroleum 15 part
adeq. to 150 part 67

what conc. of coal tar in 500 ml:-


30 part present in 195ml of prep.
x part present in 500ml of prep.
so, conc. of coal tar in 500ml=30x500/195=76.9 part

6- How many grams needed from drug in one teaspoonful , if 5 one


tspfull doses contain 7.5 gm of drug ?
a) 0.0005
b) 0.5 `
c) 500
d) 1.5
e) 1500

7-90% of substance X solution , 50% of substance X solution , how


mixing both to give 80% of substance X solution ?
a- 3: 1 90% 30
b-1:3 80%
c-10:30 50% 10
d- 5: 9
B+C
8-2 mg \ L solution , according ppm :
a-2 ppm
b-0.002 ppm
c-0.000002 ppm

ppm = mg / L
9-5mlof injection that conc. 0.4% calculate the amount of drug?
a-0.2mg c-200mg
b-2mg d-2000mg
e-20mg

10-How need prepare benzacainamid conc. 1:1000,30cc of benzocainamid


solution?
a-30 b-50 c-80
d-100 e-130

11- KI solu. Has 0.5mg/ml dissolve in 30ml water calculate the


amount of KI in the solu. ? (15mg)

12- What is The Specific gravity of substance has Weight=Y &


The volume is X ?
The Specific gravity =Density of the substance/Density of water

So, the sp. gravity of sub. =weight (Y) /volume(X)/1


So, the sp. gravity of sub. =Y/X

13- 5ml solu. amp has con. 0.2% amount of drug is :-


a-0.1mg b-1mg c-10mg
d-100mg e-1000mg

14- How many benzocaine used to prepare 1:1ooo, 80 cc


benzocaine… ( sol.=80ml)
15- the dose of drug is 0.5ml per day and the total amount of the
drug Is 100ml what is the total dose ?sol.= <200 >

16 -drug dose is 5 present in 1ml & we give 5 doses of one tea


spoonful What is the concentration by micog?

17-. A Patient weighting 80 Kg is supposed to receive a drug at a dose of 2 mg/kg/day.


What is the dose that the patient should take for each day:
A. 80 mg
B. 160 mg
C. 240 mg
D. 320 mg
E. 400 mg

18- Drug X is a given to a 70 Kg patient at an infusion rate of 0.95 mg/kg/hr. How much
drug we need for a 12-hr infusion bottle if the patient weight is 70 kg:
A. 798 mg
B.66.5 mg
C" 840 mg
C. 665 mg
D. 84 mg

19. An elixir contains 0.1 mg of drug X per ml. HOW many micrograms are there in 5
one tsp of the elixir

:
A. 0.0005 micrograms
B 0.5 micrograms
C. 500 micrograms
D. 5 micrograms
E. 1500 micrograms
20 -how many gm of water add to 5% KCL soln to make 180 gm of
solution(w\w)?

5gm--------------100

Xgm--------------180

X= 5x180/100=9 gm

So, the amount of water is:-

180 - 9 =171 gm

21- A patient cholesterol level is equal to 4mM/L. This cholesterol level can be
expressed
in terms of mg/dL (molecular weight of cholesterol = 386)
A.0.0154 mg/dL
B. 0.154 mg/dL
C. 1.54 mg/dL
D. 15.4 mg/dL
E. 154 mg/dL

mMol / L * mwt / 10 = mg / dl
Conversion from mmol/L to
E. 154 mg/dL ‫ يبقي االجابة‬38.6 ‫بنضرب في‬mg/dL
4x38.6=154.4mg/dl

22-The ppm concentration of a 6.35x1 0-6M solution of sucrose (molecular


weight of sucrose is 342.3 g/mole) is:
A. 2.174 X 10-3ppm
B.2.174 ppm

C.2.174gm/ml
C. Both A and B
D. Both Band C
ppm concentration = mass in mg / volume in liters
mass (wt ) = mole * mwt = gm

mass=6.35x10-6x342.3=2.174x10-3gm
volume=1liter‫= وبفرض ان‬2.174mg 1000 ‫يبقي نضرب في‬mg ‫الزم نحولها ل‬
B.2.174 ppm‫يبقي الحل يبقي‬

23- A 500 infusion bottle contains 11.729 of potassium chloride (KGI). How
many mEq of KCI are present? The molecular weight of KCI = 74.6:
A. 0.1571 mEq
B. 1571 mEq
C. 6.37 mEq
D. 0.00637 mEq
E. 1.72 mEq

mEq=molecular weight/valency x 1000


mEq=74.6/1x1000=0.0746gm
11.729gm_____________500ml
x_________________1ml
x=11.729/500=0.023458 gm/ml

0.023458gm__________x
0.0746gm_________1mEq
x=0.314mEq
‫‪24 - How gm of substance X must added to 2000 gm of 10%‬‬
‫‪substance X solution in order to prepare 25% of substance x‬‬
‫؟ ‪solution‬‬
‫‪a) 10000‬‬
‫‪b) 400‬‬
‫‪c) 40‬‬
‫‪d) 10‬‬
‫‪e) 0.4‬‬

‫عوزين نعرف هنضيف ‪10%‬جرام بتركيز ‪2000‬الحل سهل إن شاء هللا هو عندنا مادة وزنها‬
‫‪25%‬علشان يوصل التركيز بنسبة ‪ 100%‬أد إيه من المادة دية والذي سوف يكون بتركيز‬
‫‪(X) 100%‬‬ ‫‪15‬‬

‫‪25%‬‬

‫‪(2000gm) 10%‬‬ ‫‪75‬‬


‫‪2000gm -------------75‬‬
‫‪X gm -------------15‬‬
‫‪So, X gm =15x2000/75 =400 gm‬‬

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