Dorsal

A leftward spatial bias has been observed with visuospatial attention tasks, including line bisection and the greyscales task. Upper and lower visual field differences have been observed on various tasks, with a lower visual field advantage occurring for motion, global processing and coordinate spatial judgments. Upper visual field advantages occur for visual search, local processing and categorical judgments. In perceptual

El artículo propone algunos elementos para un balance del análisis del neoliberalismo en Nacimiento de la biopolítica. Se trata de observar algunos aciertos y límites de este curso dictado en 1979 y sus proyecciones. Se destacarán 4 aportes del curso en cuanto a la condición histórica de la racionalidad neoliberal, la perspectiva gubernamental de análisis, temas de crítica de la economía política clásica y elementos de crítica ideológica del neoliberalismo. Estos aportes, en todo caso implican actualizaciones o ajustes. Además se exponen algunos de los límites histórico-genealógicos y tecnológicos del curso. Palabras clave: neoliberalsimo, ordoliberalismo, Foucault, economía social de mercado, Modelo alemán, neoliberalismo francés. Abstract: The paper proposes some elements for a current balance of the foucauldian analysis of neoliberalism in The Birth of biopolitics. The purpose is observing some contributions and limits of the 1979 course and its projections. 4 contributions will ...

El presente trabajo de investigación parte del análisis del carácter de la ontología histórica presentada por Foucault como un pensador que se orienta desde el resto metafísico como imposibilidad de las totalizaciones. A partir de esta lógica de pensar lo político desde una ontología del acontecimiento y del rechazo de toda presunción programática y escatológica, se centrará en la constitución de su estética de la existencia, dando cuenta de la pertinencia de su metódica arqueológica-genealógica para explicar del proceso de constitución de los sujetos de deseo. El eje central de la posible discusión de Foucault con el movimiento feminista se orienta a partir de una dispersión discursiva con respecto a los modos de subjetivación contemporáneos, aunque se resaltará la noción de placer como herramienta política para la constitución de modos de vida alternativos a los modos de vida normalizados. La posibilidad de leer a Foucault desde el feminismo se centrará en las herramientas teórica...

Insects possess an antimicrobial defense response that is similar to the mammalian innate immune response. The innate immune system is designed to recognize conserved components of microorganisms called pathogen-associated molecular patterns (PAMPs). How host receptors detect PAMPs and transmit the signals to mount the immune response is being elucidated. Using GFP-Dorsal, -Dif, and -Relish reporter proteins in ex vivo assays, we demonstrate that Drosophila fat bodies, a major immune tissue, have both hemolymph-dependent and -independent responses. Microbial preparations such as lipoteichoic acid (LTA) and peptidoglycan (PGN) can stimulate some responses from dissected and rinsed larval fat bodies. Therefore, at least some aspects of recognition can occur on fat body cell surfaces, bypassing the requirement of hemolymph. Our results also show that supernatants from bacterial cultures can stimulate the nuclear translocation of Dorsal in dissected fat bodies, but this stimulation is strictly hemolymph-dependent. Various biochemical assays suggest that the factors from bacterial supernatants that stimulate the hemolymph-dependent nuclear translocation are likely made up of proteins. We further show that Dorsal mutant larvae have much lower phenoloxidase activity, consistent with a more important role of Dorsal in innate immunity than previously shown. © 2004 Wiley-Liss, Inc.

It has been suggested previously that 30% sparing of the hippocampus is enough to support spatial learning of a reference memory task in a water maze provided the spared tissue is located septally (Moser et al. 1995, Proc Natl Acad Sci USA 92:9697–9701). Therefore, the temporal hippocampus may not be involved in spatial memory. Place cells are also found in this part of the structure, and it has been suggested that these place cells have larger, less well-tuned place fields than are found in the septal hippocampus. We tested the possibility that the temporal hippocampus might be involved in spatial learning when the animals are required to distinguish between different contexts. Experiment 1 was a replication of the findings reported by Moser et al., using their protocol (8 trials/day, 6 days) and the groups with 20–40% hippocampus spared septally or temporally (volume assessed by quantitative volumetric techniques). In experiment 2, rats with also 20–40% sparing of the hippocampus either septally or temporally were trained in two water maze concurrently (four trials/day/water maze, 8 days). Rats with 20–40% hippocampus spared temporally were able to learn the two water maze tasks normally, and no difference was observed between rats with septal and temporal hippocampus spared across different measures of performance. In experiment 3, rats with 20–40% hippocampus spared septally or temporally were trained in one water maze as in experiment 1, but using a spaced training protocol similar to that of experiment 2 (four trials/day, 8 days). Rats with temporal hippocampus spared developed a preference for the training quadrant and acquired levels of performance indistinguishable from those of rats with septal hippocampus spared. The results suggest that the temporal hippocampus can support the learning of two, but also one, spatial water maze reference memory task, provided the training protocol is adequate. Hippocampus 2003;13:587–603. © 2003 Wiley-Liss, Inc.

The present research work starts from the analysis of the character of the historical ontology presented by Foucault as a thinker who is oriented from the metaphysical rest as impossibility of the totalizations. From this logic of thinking the political from an ontology of the event and the rejection of all programmatic and eschatological presumptions, it will focus on the constitution of its aesthetics of existence, giving an account of the relevance of its archaeological-genealogical method to explain the process of constituting the subjects of desire. The central axis of Foucault’s possible discussion with the feminist movement is based on a discursive dispersion with respect to contemporary modes of subjectivation, although the notion of pleasure as a political tool for the constitution of alternative ways of life to be emphasized will be highlighted. normalized ways of life. The possibility of reading Foucault from feminism will focus on the theoretical tools that the French ph...

WILLIAMS' syndrome (WS) is a rare, genetically based disorder of cognitive development. Affected individuals show a severe deficit of spatial cognition but a relative sparing of language and face recognition. To examine the possible neural basis of the spatial deficit, we tested a group ...

Pointing movements made to a target defined by the imaginary intersection of a pointer with a distant landing line were examined in healthy human observers in order to determine whether such motor responses are susceptible to the Poggendorff effect. In this well-known geometric illusion observers make systematic extrapolation errors when the pointer abuts a second line (the inducer). The kinematics of extrapolation movements, in which no explicit target was present, where similar to those made in response to a rapid-onset (explicit) dot target. The results unambiguously demonstrate that motor (pointing) responses are susceptible to the illusion. In fact, raw motor biases were greater than for perceptual responses: in the absence of an inducer (and hence also the acute angle of the Poggendorff stimulus) perceptual responses were near-veridical, whilst motor responses retained a bias. Therefore, the full Poggendorff stimulus contained two biases: one mediated by the acute angle formed between the oblique pointer and the inducing line (the classic Poggendorff effect), which affected both motor and perceptual responses equally, and another bias, which was independent of the inducer and primarily affected motor responses. We conjecture that this additional motor bias is associated with an undershoot in the unknown direction of movement and provide evidence to justify this claim. In conclusion, both manual pointing and perceptual judgements are susceptible to the well-known Poggendorff effect, supporting the notion of a unitary representation of space for action and perception or else an early locus for the effect, prior to the divergence of processing streams.