Academia.edu no longer supports Internet Explorer.
To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser.
The methanolic and aqueous extracts of Aframomum longiscapum seed were screened for In vitro antioxidant activity based on the reducing power and hydrogen peroxide scavenging activity assay. Gingerol was identified as the active principles using Gas Chromatography and Mass Spectrometry (GC-MS). Non-specifically presence and absence of tanins, saponins, cardiac glycosides, terpenoids, reducing sugars, anthraquinones, flavonoids and alkaloids were observed in the extracts by qualitative and quantitative analysis. The total flavonoids and phenolics were 11.47±1.50mgQE/g of extract and 582.00±38.11mgGAE/g for methanolic, and 13.00±4.24 mgQE/g of extract and 530.00±42.33 mgGAE/g of extract for aqueous extract respectively. The extract exhibited In vitro antioxidant activity in a concentration dependent manner with the methanolic extract showing more antioxidant activity than the aqueous extract. Results from this present work suggest that the plant has antioxidant properties and this indicates the potentials of the extracts as a source of natural antioxidant or nutraceuticals with potential application to reduce oxidative stress with potential health benefits.
BMC Complementary and Alternative Medicine
Antioxidant activity, total phenolic and total flavonoid contents of whole plant extracts Torilis leptophylla L2012 •
Ginger (Zingiber officinale Roscoe) is a herb that is well known and widely used, especially in Asia and Africa, which contains several interesting bioactive constituents and possesses health promoting properties. In this study, Phytochemical contents and antioxidant potential of Nigerian and Indian ginger were assessed in an effort to compare and validate the medicinal potential of the plant. Aqueous, hydro-methanolic and hydro-ethanolic extracts of Indian and Nigerian varieties were prepared by extraction process. Both varieties were found to contain high amount of secondary metabolites with exception of phlobotannins which happened to be in low quantity and tannins which is entirely absent in all the extracts. DPPH scavenging activity, Hydrogen peroxide and reducing power were assayed. The comparison carried out between different extracts of the two varieties using t-test at P=0.05 revealed a significant difference in terms of antioxidant activity. Indian variety was generally found to have more antioxidant activity than the Indian one with the exception of aqueous extract of Nigerian variety. This is probably due to high level of phenolics and flavonoids in the Indian variety. This study validated the medicinal potential of Zingiber officinale and established some relationship between the two varieties in terms of their antioxidant properties.
Plant-based medicines play an important role in the life of human being. In this era, some modern and ancient techniques are used to enhance the therapeutic potential of plants. Fermentation is one of the ancient techniques used to improve the medicinal effect of the plants. Gymnosporia royleana Wall. ex Lawson roots and leaves were compared with respect to their free radical scavenging potential with fermented and non-fermented extracts. Qualitative phytochemicals analysis of this plant showed the presence of important phytochemicals. The yield parameter was also measured in five different solvents, i.e., n hexane, ethyl acetate, methanol, ethanol and water. Maximum yield was shown by the methanolic leaf extract (11%) and minimum by n-hexane root extract (0.3%). Free radical scavenging effect was observed in two sets (fermented and non-fermented). Fermentation was done by b-glucosidase enzyme. Four different scavenging assays were used. In all assays, maximum scavenging potential was shown by ethyl acetate extract and minimum by n-hexane. In all assays, fermented extracts were good in their scavenging potential as compared to the non-fermented. Among all assays, plant extracts gave more positive result with phosphomolybdate assay compared to other assays. Our finding confirms that the fermentation helps in enhancing antioxidant potential of plant extract.
The exploration was to evaluate the phytochemical ingredients and antioxidant activities of annual herb Leucas indica methanolic leaves and flowers extracts. These were estimated by distinguished methods. Phytochemical constituents and non enzymatic antioxidants showed enhancement in increasing concentration from 25 mg/ml to 100 mg/ml. All the assays were carried out in triplicate and the results uttered as mean values ± standard deviations. The levels of phytochemical, explicitly phenolics, flavonoids, tannins, alkaloids, saponins, vitamin C, β-Carotene and lycopene, evidently exposed that methanolic leave extract had elevated phytochemical constituents than methanolic flower extract, except alkaloids. Same pattern was observed for antioxidant capacity assays, specifically DPPH, FRAP, reducing power assay, Hydroxyl radical scavenging activity and ABTS radical scavenging activity, this may be due the presence of high phytochemical ingredients. Even though, leave extract had superior activities than flowers extract, they both have profound therapeutic potential
Journal of Tropical Medicine
Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Aframomum melegueta Methanolic Seed Extract2014 •
Recently, Heptapleurum stellatum is commonly known in India as Umbrella tree, has a wide range of medicinal uses. This study aimed to evaluate the phytoconstituents, antioxidant activities, total phenolic content and its compound characterization in leaves. Phytochemical analysis was indicated the presence of alkaloids, carbohydrates, steroids, saponins, glycosides, and terpenoids. The total phenolic content was measured by folinciocalteau assay. The total antioxidant capacity was estimated spectrometrically by 1,1-diphenyl-2-picrylhydrazyl radical (DPPH), ferric reducing antioxidant power (FRAP) and H2O2 assay. The methanol extracts exhibited maximum antioxidant activity. A high phenolic content of 0.357-2.004 GAE/mg and potent antioxidant activity (IC50 value=80 µg/mL) was observed in methanol leaf extract. High reducing ability in the FRAP assay (IC50 value=154.24 µg/mL) and H2O2 assay (IC50 value=110 µg/mL) was also observed in methanol leaf extract of H. stellatum. Bioactive compounds were screened using GC-MS analysis. The results suggest that H. stellatum has promising antioxidant activity and could serve as a potential source of natural antioxidants.
2010 •
2012 •
2017 •
Journal of Biomedical and Pharmaceutical Research
IN VITRO ANTIOXIDANT ACTIVITY, TOTAL PHENOLIC CONTENTS AND PHYTOCHEMICAL EVALUATION FROM CRUDE EXTRACTS OF AN ENDANGERED PLANT CORDIA MACLEODII2019 •
BMC Complementary and Alternative Medicine
Assessment of phytochemicals, antioxidant, anti-lipid peroxidation and anti-hemolytic activity of extract and various fractions of Maytenus royleanus leaves2013 •
Archives of Current Research International
Assessment of in-vitro Antioxidant/Enzymes Inhibitory Potentials of Aframomum melegueta [Roscoe] K. Schum (Grains of Paradise) Leaf, Stem Bark, Seed Bark and Seed ExtractsBaltic astronomy an international journal
ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF TECTONA GRANDIS LINN. LEAVESAfrican Journal of Microbiology Research
Antioxidant, antimicrobial and cytotoxicity studies of Russelia equisetiformis2012 •
Iranian journal of pharmaceutical research : IJPR
Antioxidant and Cytotoxic Activities and Phytochemical Analysis of Euphorbia wallichii Root Extract and its Fractions2012 •
2016 •
Pharmacy and Pharmacology Research
Antioxidant and antimicrobial activities of Dialium guineense (Willd) leaf extract2013 •
Scholarena Journal of Pharmacy and Pharmacology
In-vitro-Antioxidant-and-Antimycobacterial-Activity-of-Seeds-of-Piper-longum-Linn-A-comparative-Study.pdf2014 •