Academia.edu no longer supports Internet Explorer.
To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser.
2016, The Surgery Journal
Introduction Plantar fibromatosis is a rare hyperproliferative disease of plantar aponeurosis and is also called Ledderhose disease. Case properties and treatment are discussed in this report. Case Report A 30-year-old man presented with painful bilateral plantar nodules. He had multiple and bilateral fixed and solid nodules on the plantar and medial side of his feet measuring 1 cm each. Ultrasound was performed and hypoechoic homogeneous nodules were detected. The patient underwent surgery, and the nodes were removed via a plantar incision with 2-cm safety distance. Discussion Ledderhose disease is a rare, hyperproliferative disorder of the plantar aponeurosis. The nodules are slow growing and found in the medial part of the plantar fascia. The precise etiology remains unknown. The treatment options are conservative management, steroid injections, radiotherapy, and surgery. Conclusion The main cause of this disease remains uncertain. Related conditions should be evaluated, and a pa...
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
Clinical, histological and therapeutic modern approach of Ledderhose disease2018 •
Ledderhose disease or plantar fibromatosis is a rare hyperproliferative disorder of the plantar aponeurosis, clinically characterized by nodules situated especially on the medial border of the foot. It is histopathologically associated with Dupuytren's disease. This disease has some risk factors, like old age, alcohol or nicotine abuse, liver dysfunction, trauma or exposure to vibrations and autoimmune disorders, but the exact etiology is still unknown. Even though it is benign, the local manifestations can be aggressive, leading to debilitating deformities and contractures of the toes. Ultrasound and magnetic resonance imaging are used to confirm the diagnosis and to eliminate other disorders. Whenever is possible, the conservative therapies are recommended. Having a high recurrence, Ledderhose disease can be hard to treat, needing multiple surgical interventions. This paper aims to cover all the important aspects of this disease for daily medical practice, from history to clin...
Indian dermatology online journal
Multiple nodules on the sole of the footLedderhose disease, or plantar fibromatosis, is a benign hyperproliferative disorder of the plantar aponeurosis. It presents as one or more round, firm slow-growing plaques or nodules on the plantar surface of the foot, typically on the medial side. The etiology is unknown, though it has been associated with trauma, liver disease, diabetes mellitus, epilepsy and alcoholism. Histopathological examination of plantar fibromatosis reveals dense fibrocellular tissue with parallel and nodular arrays of fibrocytes and fibrillar collagen with a distinctive cork-screw morphology. The differential diagnosis includes various fibroblastic and myofibroblastic proliferations.
The International Journal of Lower Extremity Wounds
Squamous Cell Carcinoma and Ledderhose Disease: A Case Report2013 •
Ledderhose disease is a rare hyperproliferative disorder of fibrous tissue. We present the case of a 40-year-old man who presented with bilateral plantar fibromatosis, dupuytren contracture and keloid, with partial response to oral acitretin.
Plastic and Reconstructive Surgery - Global Open
Unusual Intranodular Collagenase Injection: A Case of Bilateral Ledderhose Disease2020 •
Summary: Ledderhose disease (LD) is a rare plantar fibromatosis of the foot, frequently associated with Dupuytren disease. Collagenase of Clostridium hystoliticum has recently revolutionized the way to treat Dupuytren disease. Nevertheless, the literature is still critically lacking about the use of collagenase injection in LD. We report a case of a man with bilateral symptomatic LD treated with collagenase. Injections (0.58 mg of collagenase of C. hystoliticum) were performed into nodules. Forced extension after injection was not performed. The patient could walk normally immediately after procedure. The procedure was a complete success without side effects or complications on either foot. Currently, at 14 months after treatment of the right foot and 12 months after treatment of the left foot, no recurrence has been observed. Collagenase injection was only effective in treating symptomatic LD in this one patient we reported on.
Foot & ankle international
Classification and treatment of plantar fibromatosis2000 •
A retrospective study of 18 patients (23 feet) with plantar fibromatosis who required surgical excision between January, 1991, and June, 1998, was performed. Subtotal plantar fasciectomy was performed to remove the tumor with a wide disease-free margin. 16 patients (21 feet) were interviewed and 14 patients (19 feet) were examined with an average followup of 36 months. Two patients (2 feet) with less than 12 months followup were excluded. Both subjective and objective evaluations and pre- and postoperative x-rays were reviewed to assess the alignment of the bony arch. There were nine males and nine females, age 49 years, average, at the time of diagnosis. Sixty-seven percent of patients had bilateral disease, and 28% had associated Dupuytren's contracture. There were 18 primary and five recurrent tumors. An operative staging system, I to IV, for plantar fibromatosis is presented which incorporates the extent of plantar fascia involvement, the presence of skin adherence, and the ...
Cumhuriyetin Birinci Yüzyılında Anadolu’da Türk Dönemi Arkeoloji Çalışmaları
Kütahya Kalesi Kazısı / Kütahya Castle Excavation2023 •
2013 •
La caza ha sido entendida en muchas ocasiones, desde una perspectiva evolucionista, como un estadio anterior a la complejidad social, económica y política. Es cierto que su aportación al sustento alimenticio de la población de Egipto disminuyó en tiempos predinásticos y que la relación con los animales salvajes, exóticos, se ritualizó con la materialización de una ideología o cultura asociada al faraón, pero la caza, al igual que la pesca, siguió proporcionando unos productos que eran demandados por la sociedad. Se trata de una actividad que debe ser analizada teniendo en cuenta los planteamientos antropológicos, arqueológicos y artísticos para entender mejor su simbolismo y presencia en la memoria cultural del Egipto faraónico. Hunting has been understood on many occasions from an evolutionary perspective, as a stage prior to social, economic and political complexity. It is true that its contribution to the food sustenance of the Egyptian population decreased in predynastic times and that the relationship with wild, exotic animals was ritualized with the materialization of an ideology or culture associated with the pharaoh, but hunting, like fishing, continued to provide products that were demanded by society. It is an activity that must be analyzed considering anthropological, archeological and artistic approaches to better understand its symbolism and presence in the cultural memory of Pharaonic Egypt.
Historische Zeitschrift
Sonya Nevin, The Idea of Marathon. Battle and Culture. Berlin, Bloomsbury Verlag GmbH 2022Philologica Jassiensia, nr. 2 (38)
Alexe Marin, traducătorul lucrării Prescurtare de astronomie populară (1839)2023 •
Proceedings of the 8th International Conference on Advanced Materials and Systems
Design thinking in product development - case study: leather library2020 •
HAL (Le Centre pour la Communication Scientifique Directe)
Aeroelastic Adjoint-Based Optimisation of an Highly Flexible Aircraft Wing Configuration2022 •
2017 International Conference on Indoor Positioning and Indoor Navigation (IPIN)
Multiple simultaneous Wi-Fi measurements in fingerprinting indoor positioning2017 •
2024 •
arXiv (Cornell University)
Justification logic and the epistemic contribution of deduction2022 •
2012 •
Journal of Public Health
Correlation between the rise of COVID-19 cases and Montenegrin’s government new economic plan2022 •