JWH-161

JWH-161
(IUPAC) ime
	(4aR,13bR)-2,5,5-trimetil-8-pentil-3,4,4a,5,8,13b-heksahidroizohromeno[3,4-b]karbazol-13-ol
Klinički podaci
Identifikatori
ATC kod	nije dodeljen
PubChem	10431286
Hemijski podaci
Formula	C27H33NO2
Mol. masa	403,555 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C27H33NO2/c1-5-6-9-14-28-21-11-8-7-10-18(21)24-22(28)16-23-25(26(24)29)19-15-17(2)12-13-20(19)27(3,4)30-23/h7-8,10-11,15-16,19-20,29H,5-6,9,12-14H2,1-4H3 ; Key: VDJUAFPNHZRTNL-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

JWH-161 je kanabinoidni derivat koji je hibrid između dibenzopiranskih "klasičnih" kanabinoidnih lekova i novijih indolnih derivata. JWH-161 ima CB₁ K_i od 19,0 nM. U studijama na životinjama je utvrđeno da je malo slabiji od THC.^[3]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Huffman JW, Padgett LW (2005). „Recent developments in the medicinal chemistry of cannabimimetic indoles, pyrroles and indenes”. Current Medicinal Chemistry 12 (12): 1395–411. DOI:10.2174/0929867054020864. PMID 15974991.

Spoljašnje veze

	Portal Medicina
	Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[pmid15974991-3] Huffman JW, Padgett LW (2005). „Recent developments in the medicinal chemistry of cannabimimetic indoles, pyrroles and indenes”. Current Medicinal Chemistry 12 (12): 1395–411. DOI:10.2174/0929867054020864. PMID 15974991.

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