ZA982818B - Prevention of breast cancer using selective estrogen receptor modulators. - Google Patents

Prevention of breast cancer using selective estrogen receptor modulators.

Info

Publication number: ZA982818B
Authority: ZA; South Africa
Prior art keywords: prevention; breast cancer; estrogen receptor; receptor modulators; selective estrogen
Prior art date: 1997-04-09

Application number

ZA9802818A

Other languages

English (en)

Inventor

Andrew Lawrence Glasebrook

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-09

Filing date

1998-04-02

Publication date

1999-10-04

1998-04-02 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1999-10-04 Publication of ZA982818B publication Critical patent/ZA982818B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)

ZA9802818A 1997-04-09 1998-04-02 Prevention of breast cancer using selective estrogen receptor modulators. ZA982818B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US4311897P	1997-04-09	1997-04-09

Publications (1)

Publication Number	Publication Date
ZA982818B true ZA982818B (en)	1999-10-04

Family

ID=21925594

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9802818A ZA982818B (en)	1997-04-09	1998-04-02	Prevention of breast cancer using selective estrogen receptor modulators.

Country Status (15)

Country	Link
EP (1)	EP0975628A4 (xx)
JP (1)	JP2001518897A (xx)
KR (1)	KR20010006215A (xx)
CN (1)	CN1259945A (xx)
AU (1)	AU6957398A (xx)
CA (1)	CA2286207A1 (xx)
EA (1)	EA199900910A1 (xx)
HU (1)	HUP0001845A2 (xx)
ID (1)	ID23653A (xx)
IL (1)	IL132279A0 (xx)
NO (1)	NO994902L (xx)
PL (1)	PL336206A1 (xx)
TR (1)	TR199903244T2 (xx)
WO (1)	WO1998045286A1 (xx)
ZA (1)	ZA982818B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6610706B1 (en)	1999-07-29	2003-08-26	Eli Lilly And Company	Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride
US6653479B1 (en)	1999-07-29	2003-11-25	Eli Lilly And Company	Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b] thiophene hydrochloride
EA022760B1 (ru)	2007-10-16	2016-02-29	Репрос Терапьютикс Инк.	Применение транс-кломифена для предотвращения или лечения диабета 2 типа у мужчин
AU2013225869B2 (en)	2012-02-29	2017-06-08	Repros Therapeutics Inc.	Combination therapy for treating androgen deficiency
MA38325B1 (fr)	2013-02-19	2019-03-29	Novartis Ag	Dérivés de benzothiophène et compositions correspondantes en tant qu'agents de dégradation sélectifs des récepteurs des œstrogènes
GB201311888D0 (en) *	2013-07-03	2013-08-14	Glaxosmithkline Ip Dev Ltd	Novel compounds
JP7048505B2 (ja)	2015-11-10	2022-04-05	パラクリンセラピューティクスエービー	Ｐｄｇｆ－ｃｃ阻害剤および抗エストロゲン剤によるｅｒ陰性乳癌の処置

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3989569B2 (ja) *	1995-02-28	2007-10-10	イーライリリーアンドカンパニー	ベンゾチオフェン化合物、中間体、組成物および方法
US5510357A (en) *	1995-02-28	1996-04-23	Eli Lilly And Company	Benzothiophene compounds as anti-estrogenic agents
US5731342A (en) *	1996-02-22	1998-03-24	Eli Lilly And Company	Benzothiophenes, formulations containing same, and methods

1998
- 1998-04-02 ZA ZA9802818A patent/ZA982818B/xx unknown
- 1998-04-07 CA CA002286207A patent/CA2286207A1/en not_active Abandoned
- 1998-04-07 WO PCT/US1998/006989 patent/WO1998045286A1/en not_active Application Discontinuation
- 1998-04-07 TR TR1999/03244T patent/TR199903244T2/xx unknown
- 1998-04-07 KR KR1019997009295A patent/KR20010006215A/ko not_active Application Discontinuation
- 1998-04-07 CN CN98805957A patent/CN1259945A/zh active Pending
- 1998-04-07 PL PL98336206A patent/PL336206A1/xx unknown
- 1998-04-07 AU AU69573/98A patent/AU6957398A/en not_active Abandoned
- 1998-04-07 EA EA199900910A patent/EA199900910A1/ru unknown
- 1998-04-07 ID IDW991189A patent/ID23653A/id unknown
- 1998-04-07 EP EP98915368A patent/EP0975628A4/en not_active Withdrawn
- 1998-04-07 IL IL13227998A patent/IL132279A0/xx unknown
- 1998-04-07 HU HU0001845A patent/HUP0001845A2/hu unknown
- 1998-04-07 JP JP54309098A patent/JP2001518897A/ja active Pending
1999
- 1999-10-08 NO NO994902A patent/NO994902L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0975628A4 (en)	2001-03-21
EP0975628A1 (en)	2000-02-02
WO1998045286A1 (en)	1998-10-15
TR199903244T2 (xx)	2000-05-22
CN1259945A (zh)	2000-07-12
ID23653A (id)	2000-05-11
HUP0001845A2 (hu)	2001-06-28
NO994902L (no)	1999-12-07
NO994902D0 (no)	1999-10-08
KR20010006215A (ko)	2001-01-26
AU6957398A (en)	1998-10-30
CA2286207A1 (en)	1998-10-15
EA199900910A1 (ru)	2000-04-24
IL132279A0 (en)	2001-03-19
JP2001518897A (ja)	2001-10-16
PL336206A1 (en)	2000-06-05

Publication	Publication Date	Title
ZA200108846B (en)	2002-12-24	Glucocorticoid receptor modulators.
HK1035671A1 (en)	2001-12-07	Adenosine a3 receptor modulators.
EP0971588A4 (en)	2000-12-27	NEW CANNABINOID RECEPTOR MODULATORS
AU4557099A (en)	1999-12-30	Novel therapeutic agents that modulate estrogen receptors
ZA991301B (en)	1999-09-13	Glutamate receptor modulators.
AU1199600A (en)	2000-04-26	Estrogen receptor ligands
ZA966721B (en)	1997-02-18	Bowl for hand mixing.
MXPA01011294A (es)	2003-08-01	Compuestos moduladores de receptor de progesterona tetraciclicos y metodos.
GB9517098D0 (en)	1995-10-25	Receptor
ZA982818B (en)	1999-10-04	Prevention of breast cancer using selective estrogen receptor modulators.
EP1084142A4 (en)	2005-01-19	GPR35A RECEIVER
GB9715815D0 (en)	1997-10-01	Histamine H receptor ligands
ZA981338B (en)	1999-08-18	Neurturin receptor.
GB9928566D0 (en)	2000-02-02	Human vanilloid receptor-like receptor
GB9715816D0 (en)	1997-10-01	Histamine H receptor ligands
GB9803062D0 (en)	1998-04-08	Estrogen receptor ligands
GB9913649D0 (en)	1999-08-11	Estrogen receptor
GB9722884D0 (en)	1998-01-07	Estrogen receptor
GB9717346D0 (en)	1997-10-22	Estrogen receptor ligands
GB9711992D0 (en)	1997-08-06	Estrogen receptor ligands
GB9806032D0 (en)	1998-05-20	Estrogen receptor
EP1109565A4 (en)	2004-05-19	GABAB1AA RECEPTOR
GB9803202D0 (en)	1998-04-08	Estrogen Receptor Ligands
GB9803061D0 (en)	1998-04-08	Estrogen receptor ligands
GB9808613D0 (en)	1998-06-24	Receptor system