AU6957398A - Prevention of breast cancer with selective estrogen receptor modulators - Google Patents

Prevention of breast cancer with selective estrogen receptor modulators Download PDF

Info

Publication number: AU6957398A
Authority: AU; Australia
Prior art keywords: thiophene; benzo; compound; hydroxy; pct
Prior art date: 1997-04-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU69573/98A

Other languages

English (en)

Inventor

Andrew Lawrence Glasebrook

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-09

Filing date

1998-04-07

Publication date

1998-10-30

1998-04-07 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

1998-10-30 Publication of AU6957398A publication Critical patent/AU6957398A/en

Status Abandoned legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)

AU69573/98A 1997-04-09 1998-04-07 Prevention of breast cancer with selective estrogen receptor modulators Abandoned AU6957398A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US4311897P	1997-04-09	1997-04-09
US60043118		1997-04-09
PCT/US1998/006989 WO1998045286A1 (en)	1997-04-09	1998-04-07	Prevention of breast cancer with selective estrogen receptor modulators

Publications (1)

Publication Number	Publication Date
AU6957398A true AU6957398A (en)	1998-10-30

Family

ID=21925594

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU69573/98A Abandoned AU6957398A (en)	1997-04-09	1998-04-07	Prevention of breast cancer with selective estrogen receptor modulators

Country Status (15)

Country	Link
EP (1)	EP0975628A4 (xx)
JP (1)	JP2001518897A (xx)
KR (1)	KR20010006215A (xx)
CN (1)	CN1259945A (xx)
AU (1)	AU6957398A (xx)
CA (1)	CA2286207A1 (xx)
EA (1)	EA199900910A1 (xx)
HU (1)	HUP0001845A2 (xx)
ID (1)	ID23653A (xx)
IL (1)	IL132279A0 (xx)
NO (1)	NO994902L (xx)
PL (1)	PL336206A1 (xx)
TR (1)	TR199903244T2 (xx)
WO (1)	WO1998045286A1 (xx)
ZA (1)	ZA982818B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6610706B1 (en)	1999-07-29	2003-08-26	Eli Lilly And Company	Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride
US6653479B1 (en)	1999-07-29	2003-11-25	Eli Lilly And Company	Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b] thiophene hydrochloride
EA022760B1 (ru)	2007-10-16	2016-02-29	Репрос Терапьютикс Инк.	Применение транс-кломифена для предотвращения или лечения диабета 2 типа у мужчин
AU2013225869B2 (en)	2012-02-29	2017-06-08	Repros Therapeutics Inc.	Combination therapy for treating androgen deficiency
MA38325B1 (fr)	2013-02-19	2019-03-29	Novartis Ag	Dérivés de benzothiophène et compositions correspondantes en tant qu'agents de dégradation sélectifs des récepteurs des œstrogènes
GB201311888D0 (en) *	2013-07-03	2013-08-14	Glaxosmithkline Ip Dev Ltd	Novel compounds
JP7048505B2 (ja)	2015-11-10	2022-04-05	パラクリンセラピューティクスエービー	Ｐｄｇｆ－ｃｃ阻害剤および抗エストロゲン剤によるｅｒ陰性乳癌の処置

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP3989569B2 (ja) *	1995-02-28	2007-10-10	イーライリリーアンドカンパニー	ベンゾチオフェン化合物、中間体、組成物および方法
US5510357A (en) *	1995-02-28	1996-04-23	Eli Lilly And Company	Benzothiophene compounds as anti-estrogenic agents
US5731342A (en) *	1996-02-22	1998-03-24	Eli Lilly And Company	Benzothiophenes, formulations containing same, and methods

1998
- 1998-04-02 ZA ZA9802818A patent/ZA982818B/xx unknown
- 1998-04-07 CA CA002286207A patent/CA2286207A1/en not_active Abandoned
- 1998-04-07 WO PCT/US1998/006989 patent/WO1998045286A1/en not_active Application Discontinuation
- 1998-04-07 TR TR1999/03244T patent/TR199903244T2/xx unknown
- 1998-04-07 KR KR1019997009295A patent/KR20010006215A/ko not_active Application Discontinuation
- 1998-04-07 CN CN98805957A patent/CN1259945A/zh active Pending
- 1998-04-07 PL PL98336206A patent/PL336206A1/xx unknown
- 1998-04-07 AU AU69573/98A patent/AU6957398A/en not_active Abandoned
- 1998-04-07 EA EA199900910A patent/EA199900910A1/ru unknown
- 1998-04-07 ID IDW991189A patent/ID23653A/id unknown
- 1998-04-07 EP EP98915368A patent/EP0975628A4/en not_active Withdrawn
- 1998-04-07 IL IL13227998A patent/IL132279A0/xx unknown
- 1998-04-07 HU HU0001845A patent/HUP0001845A2/hu unknown
- 1998-04-07 JP JP54309098A patent/JP2001518897A/ja active Pending
1999
- 1999-10-08 NO NO994902A patent/NO994902L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
ZA982818B (en)	1999-10-04
EP0975628A4 (en)	2001-03-21
EP0975628A1 (en)	2000-02-02
WO1998045286A1 (en)	1998-10-15
TR199903244T2 (xx)	2000-05-22
CN1259945A (zh)	2000-07-12
ID23653A (id)	2000-05-11
HUP0001845A2 (hu)	2001-06-28
NO994902L (no)	1999-12-07
NO994902D0 (no)	1999-10-08
KR20010006215A (ko)	2001-01-26
CA2286207A1 (en)	1998-10-15
EA199900910A1 (ru)	2000-04-24
IL132279A0 (en)	2001-03-19
JP2001518897A (ja)	2001-10-16
PL336206A1 (en)	2000-06-05

Publication	Publication Date	Title
US5723474A (en)	1998-03-03	Benzothiophene compounds, intermediates, compositions, and methods
AU733421B2 (en)	2001-05-17	Treatment of central nervous system disorders with selective estrogen receptor modulators
IL117276A (en)	2001-10-31	Benziophene compounds, their preparation and their related compositions
AU6966198A (en)	1998-10-30	Treatment or prophylaxis of prostatic cancer and benign prostatic hyperplasia with selective estrogen receptor modulators
AU6957398A (en)	1998-10-30	Prevention of breast cancer with selective estrogen receptor modulators
US5856340A (en)	1999-01-05	Method of treating estrogen dependent cancers
US5998441A (en)	1999-12-07	Benzothiophene compounds, intermediates, compositions, and methods
EP0873992B1 (en)	2002-09-25	Indene compounds having activity as SERMs
CA2216592C (en)	2006-07-18	Benzothiophene compounds, intermediates, compositions, and methods
US5856339A (en)	1999-01-05	Benzothiophene compounds, intermediates, compositions, and methods
MXPA99009234A (en)	2000-06-01	Prevention of breast cancer with selective estrogen receptor modulators
US5977093A (en)	1999-11-02	Benzothiophene compounds, intermediates, compositions, and methods
CA2170479C (en)	2009-04-14	Benzothiophene compounds, intermediates, compositions, and methods
CZ355399A3 (cs)	2000-08-16	Léčivo k prevenci karcinomu prsu
EP1641774B1 (en)	2008-09-03	Pentafluoroalkanesulfinyl naphthalenes and related estrogen receptor modulators
MXPA99009233A (en)	2000-07-01	Treatment or prophylaxis of prostatic cancer and benign prostatic hyperplasia with selective estrogen receptor modulators
CZ9903554A3 (cs)	2000-10-11	Způsob léčby nebo profylaxe rakoviny prostaty a benigní hyperplasie prostaty modulátory selektivního receptorů estrogenu
MXPA99009228A (en)	2000-06-01	Treatment of central nervous system disorders with selective estrogen receptor modulators

Legal Events

Date	Code	Title	Description
2002-09-05	MK5	Application lapsed section 142(2)(e) - patent request and compl. specification not accepted