ZA982818B - Prevention of breast cancer using selective estrogen receptor modulators. - Google Patents

Prevention of breast cancer using selective estrogen receptor modulators.

Info

Publication number: ZA982818B
Authority: ZA; South Africa
Prior art keywords: prevention; breast cancer; estrogen receptor; receptor modulators; selective estrogen
Prior art date: 1997-04-09

Application number

ZA9802818A

Inventor

Andrew Lawrence Glasebrook

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-09

Filing date

1998-04-02

Publication date

1999-10-04

1998-04-02 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1999-10-04 Publication of ZA982818B publication Critical patent/ZA982818B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)

ZA9802818A 1997-04-09 1998-04-02 Prevention of breast cancer using selective estrogen receptor modulators. ZA982818B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US4311897P	1997-04-09	1997-04-09

Publications (1)

Publication Number	Publication Date
ZA982818B true ZA982818B (en)	1999-10-04

Family

ID=21925594

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9802818A ZA982818B (en)	1997-04-09	1998-04-02	Prevention of breast cancer using selective estrogen receptor modulators.

Country Status (15)

Country	Link
EP (1)	EP0975628A4 (en)
JP (1)	JP2001518897A (en)
KR (1)	KR20010006215A (en)
CN (1)	CN1259945A (en)
AU (1)	AU6957398A (en)
CA (1)	CA2286207A1 (en)
EA (1)	EA199900910A1 (en)
HU (1)	HUP0001845A2 (en)
ID (1)	ID23653A (en)
IL (1)	IL132279A0 (en)
NO (1)	NO994902L (en)
PL (1)	PL336206A1 (en)
TR (1)	TR199903244T2 (en)
WO (1)	WO1998045286A1 (en)
ZA (1)	ZA982818B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6653479B1 (en)	1999-07-29	2003-11-25	Eli Lilly And Company	Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b] thiophene hydrochloride
US6610706B1 (en)	1999-07-29	2003-08-26	Eli Lilly And Company	Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride
JP5558358B2 (en)	2007-10-16	2014-07-23	レプロスセラピューティクスインコーポレイティド	TRANS-clomiphene for metabolic syndrome
HK1204979A1 (en)	2012-02-29	2015-12-11	Repros Therapeutics Inc.	Combination therapy for treating androgen deficiency
PE20151428A1 (en)	2013-02-19	2015-09-24	Novartis Ag	BENZOTHIOPHENE DERIVATIVES AND COMPOSITIONS THEREOF AS SELECTIVE DEGRADANTS OF ESTROGEN RECEPTORS
GB201311888D0 (en) *	2013-07-03	2013-08-14	Glaxosmithkline Ip Dev Ltd	Novel compounds
JP7048505B2 (en)	2015-11-10	2022-04-05	パラクリンセラピューティクスエービー	Treatment of ER-negative breast cancer with PDGF-CC inhibitors and antiestrogens

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5510357A (en) *	1995-02-28	1996-04-23	Eli Lilly And Company	Benzothiophene compounds as anti-estrogenic agents
EP0729956B1 (en) *	1995-02-28	2001-10-31	Eli Lilly And Company	Benzothiophene compounds, intermediates, compositions, and methods
US5731342A (en) *	1996-02-22	1998-03-24	Eli Lilly And Company	Benzothiophenes, formulations containing same, and methods

1998
- 1998-04-02 ZA ZA9802818A patent/ZA982818B/en unknown
- 1998-04-07 HU HU0001845A patent/HUP0001845A2/en unknown
- 1998-04-07 AU AU69573/98A patent/AU6957398A/en not_active Abandoned
- 1998-04-07 JP JP54309098A patent/JP2001518897A/en active Pending
- 1998-04-07 KR KR1019997009295A patent/KR20010006215A/en not_active Withdrawn
- 1998-04-07 TR TR1999/03244T patent/TR199903244T2/en unknown
- 1998-04-07 EA EA199900910A patent/EA199900910A1/en unknown
- 1998-04-07 WO PCT/US1998/006989 patent/WO1998045286A1/en not_active Application Discontinuation
- 1998-04-07 EP EP98915368A patent/EP0975628A4/en not_active Withdrawn
- 1998-04-07 PL PL98336206A patent/PL336206A1/en unknown
- 1998-04-07 IL IL13227998A patent/IL132279A0/en unknown
- 1998-04-07 ID IDW991189A patent/ID23653A/en unknown
- 1998-04-07 CN CN98805957A patent/CN1259945A/en active Pending
- 1998-04-07 CA CA002286207A patent/CA2286207A1/en not_active Abandoned
1999
- 1999-10-08 NO NO994902A patent/NO994902L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
PL336206A1 (en)	2000-06-05
NO994902L (en)	1999-12-07
KR20010006215A (en)	2001-01-26
HUP0001845A2 (en)	2001-06-28
WO1998045286A1 (en)	1998-10-15
CN1259945A (en)	2000-07-12
EP0975628A4 (en)	2001-03-21
IL132279A0 (en)	2001-03-19
EA199900910A1 (en)	2000-04-24
EP0975628A1 (en)	2000-02-02
CA2286207A1 (en)	1998-10-15
AU6957398A (en)	1998-10-30
ID23653A (en)	2000-05-11
NO994902D0 (en)	1999-10-08
JP2001518897A (en)	2001-10-16
TR199903244T2 (en)	2000-05-22

Publication	Publication Date	Title
ZA200108846B (en)	2002-12-24	Glucocorticoid receptor modulators.
EP0971588A4 (en)	2000-12-27	Novel cannabinoid receptor modulators
GB2353527B (en)	2004-02-25	Adenosine A3 receptor modulators
ZA991301B (en)	1999-09-13	Glutamate receptor modulators.
AU1199600A (en)	2000-04-26	Estrogen receptor ligands
HUP9700636A3 (en)	1999-01-28	Novel estrogen receptor
MXPA01011294A (en)	2003-08-01	Tetracyclic progesterone receptor modulator compounds and methods.
GB9517098D0 (en)	1995-10-25	Receptor
ZA982818B (en)	1999-10-04	Prevention of breast cancer using selective estrogen receptor modulators.
EP1084142A4 (en)	2005-01-19	Gpr35a receptor
GB9715815D0 (en)	1997-10-01	Histamine H receptor ligands
ZA981338B (en)	1999-08-18	Neurturin receptor.
GB9928566D0 (en)	2000-02-02	Human vanilloid receptor-like receptor
GB9715816D0 (en)	1997-10-01	Histamine H receptor ligands
GB9803062D0 (en)	1998-04-08	Estrogen receptor ligands
GB9913649D0 (en)	1999-08-11	Estrogen receptor
EP1083909A4 (en)	2002-01-02	hCEPR RECEPTOR
IL135674A0 (en)	2001-05-20	Hi-tv integrated communication system
GB9722884D0 (en)	1998-01-07	Estrogen receptor
GB9711992D0 (en)	1997-08-06	Estrogen receptor ligands
GB9717346D0 (en)	1997-10-22	Estrogen receptor ligands
GB9806032D0 (en)	1998-05-20	Estrogen receptor
EP1109565A4 (en)	2004-05-19	Gabab1aa receptor
GB9803202D0 (en)	1998-04-08	Estrogen Receptor Ligands
GB9803061D0 (en)	1998-04-08	Estrogen receptor ligands