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ZA200803356B - Methods for controlling gene expression using ta-siRNA - Google Patents

Methods for controlling gene expression using ta-siRNA

Info

Publication number
ZA200803356B
ZA200803356B ZA200803356A ZA200803356A ZA200803356B ZA 200803356 B ZA200803356 B ZA 200803356B ZA 200803356 A ZA200803356 A ZA 200803356A ZA 200803356 A ZA200803356 A ZA 200803356A ZA 200803356 B ZA200803356 B ZA 200803356B
Authority
ZA
South Africa
Prior art keywords
sirna
methods
gene expression
controlling gene
controlling
Prior art date
Application number
ZA200803356A
Other languages
English (en)
Inventor
Ren Peifeng
Song Hee-Sook
Mcmillan John
Wang Yuwen
Original Assignee
Basf Plant Science Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Plant Science Gmbh filed Critical Basf Plant Science Gmbh
Publication of ZA200803356B publication Critical patent/ZA200803356B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8209—Selection, visualisation of transformants, reporter constructs, e.g. antibiotic resistance markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/825—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving pigment biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
ZA200803356A 2005-09-20 2008-04-16 Methods for controlling gene expression using ta-siRNA ZA200803356B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71864505P 2005-09-20 2005-09-20

Publications (1)

Publication Number Publication Date
ZA200803356B true ZA200803356B (en) 2009-09-30

Family

ID=37651152

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200803356A ZA200803356B (en) 2005-09-20 2008-04-16 Methods for controlling gene expression using ta-siRNA

Country Status (8)

Country Link
US (1) US9708619B2 (xx)
EP (2) EP2980220A1 (xx)
CN (1) CN101268194A (xx)
AU (1) AU2006298844B2 (xx)
CA (1) CA2620387C (xx)
IL (3) IL189494A (xx)
WO (1) WO2007039454A1 (xx)
ZA (1) ZA200803356B (xx)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR052061A1 (es) * 2004-12-20 2007-02-28 Basf Plant Science Gmbh Moleculas de acido nucleico que codifican genes de desaturasa de acidos grasos de plantas y metodos de uso
US20060200878A1 (en) 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
US8030473B2 (en) 2005-01-07 2011-10-04 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method to trigger RNA interference
WO2008133643A2 (en) 2006-10-12 2008-11-06 Monsanto Technology, Llc Plant micrornas and methods of use thereof
AU2008286701B2 (en) 2007-08-14 2015-02-12 Commonwealth Scientific And Industrial Research Organisation Improved gene silencing methods
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
US20110061122A1 (en) 2008-01-22 2011-03-10 Ceres, Inc. Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics in response to cold
US12024713B2 (en) 2008-01-22 2024-07-02 Ceres, Inc. Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics in response to cold
CA2771252C (en) 2009-08-31 2019-03-12 Basf Plant Science Company Gmbh Regulatory nucleic acid molecules for enhancing constitutive gene expression in plants
CA3167819A1 (en) 2009-08-31 2011-03-03 Basf Plant Science Company Gmbh Regulatory nucleic acid molecules for enhancing seed-specific and/or seed-preferential gene expression in plants
CN106222166B (zh) 2009-08-31 2020-09-08 巴斯夫植物科学有限公司 用于在植物中增强种子特异性基因表达而促进增强的多不饱和脂肪酸合成的调节性核酸分子
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
EP3231872B1 (en) * 2010-03-08 2020-05-06 Monsanto Technology LLC Polynucleotide molecules for gene regulation in plants
CN102719433B (zh) * 2011-03-30 2013-07-17 华中农业大学 osa-MIR167a基因在调控水稻株型中的应用
US20120278929A1 (en) 2011-04-28 2012-11-01 Iowa State University Research Foundation, Inc. miRNA396 AND GROWTH REGULATING FACTORS FOR CYST NEMATODE TOLERANCE IN PLANTS
CN109997852A (zh) 2011-09-13 2019-07-12 孟山都技术公司 用于杂草控制的方法和组合物
US9840715B1 (en) 2011-09-13 2017-12-12 Monsanto Technology Llc Methods and compositions for delaying senescence and improving disease tolerance and yield in plants
UY34333A (es) * 2011-09-13 2013-04-30 Monsanto Technology Llc ?métodos y composiciones para el control de malezas, y métodos para reducir la expresión de enzima dhps?
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
UA116090C2 (uk) 2011-09-13 2018-02-12 Монсанто Текнолоджи Ллс Спосіб та композиція для боротьби з бур'янами (варіанти)
UA115535C2 (uk) 2011-09-13 2017-11-27 Монсанто Текнолоджи Ллс Спосіб та композиція для боротьби з бур'янами (варіанти)
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
MX377067B (es) 2011-09-13 2025-03-07 Monsanto Tech Llc Métodos y composiciones para el control de malezas.
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
US9920326B1 (en) 2011-09-14 2018-03-20 Monsanto Technology Llc Methods and compositions for increasing invertase activity in plants
CN103172716B (zh) * 2011-12-26 2014-12-17 中国科学院上海生命科学研究院 植物抗热基因及其应用
CN104497114B (zh) * 2011-12-26 2017-05-24 中国科学院上海生命科学研究院 植物抗热基因htt2及其应用
US10240162B2 (en) * 2012-05-24 2019-03-26 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
WO2013184768A1 (en) 2012-06-05 2013-12-12 University Of Georgia Research Foundation, Inc. Compositions and methods of gene silencing in plants
BR112015008706A2 (pt) 2012-10-18 2018-02-06 Monsanto Technology Llc métodos e composições para controle de praga de plantas
WO2014093479A1 (en) * 2012-12-11 2014-06-19 Montana State University Crispr (clustered regularly interspaced short palindromic repeats) rna-guided control of gene regulation
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
MX375327B (es) * 2013-01-01 2025-03-06 A B Seeds Ltd Métodos para introducir dsrna en semillas de plantas para modular la expresión genética.
US10000767B2 (en) 2013-01-28 2018-06-19 Monsanto Technology Llc Methods and compositions for plant pest control
WO2014164797A2 (en) 2013-03-13 2014-10-09 Monsanto Technology Llc Methods and compositions for weed control
CA2905027A1 (en) 2013-03-13 2014-10-09 Monsanto Technology Llc Methods and compositions for weed control
US20140283211A1 (en) 2013-03-14 2014-09-18 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
ES2703169T3 (es) 2013-05-14 2019-03-07 Bayer Cropscience Nv Expresión selectiva mejorada de transgenes en plantas productoras de fibra
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
PL3030663T3 (pl) 2013-07-19 2020-04-30 Monsanto Technology Llc Kompozycje i sposoby kontroli leptinotarsa
ES3008698T3 (en) 2013-11-04 2025-03-24 Greenlight Biosciences Inc Compositions and methods for controlling arthropod parasite and pest infestations
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
EP3116303B1 (en) 2014-01-15 2020-07-22 Monsanto Technology LLC Methods and compositions for weed control using epsps polynucleotides
WO2015153339A2 (en) 2014-04-01 2015-10-08 Monsanto Technology Llc Compositions and methods for controlling insect pests
CN103923864B (zh) * 2014-04-24 2016-08-17 江南大学 一株高黄酮类化合物耐受性大肠杆菌工程菌及其构建方法和应用
CN104046628A (zh) * 2014-05-23 2014-09-17 浙江农林大学 一种重组植物ta-siRNA基因及应用
US10988764B2 (en) 2014-06-23 2021-04-27 Monsanto Technology Llc Compositions and methods for regulating gene expression via RNA interference
WO2015200539A1 (en) 2014-06-25 2015-12-30 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
WO2016018887A1 (en) 2014-07-29 2016-02-04 Monsanto Technology Llc Compositions and methods for controlling insect pests
RU2723049C2 (ru) 2015-01-22 2020-06-08 Монсанто Текнолоджи Ллс Композиции и способы борьбы с leptinotarsa
AU2016270870A1 (en) 2015-06-02 2018-01-04 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
AU2016270913A1 (en) 2015-06-03 2018-01-04 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
CN105825547B (zh) * 2016-03-11 2019-01-29 西安电子科技大学 一种基于体素和自适应光传输模型的光学三维成像方法
US11859196B2 (en) 2016-03-15 2024-01-02 National Research Council Of Canada Modulating drought tolerance in Brassicaceae using the Kanghan gene family
AU2017232723B2 (en) 2016-03-15 2023-04-20 National Research Council Of Canada Modulating plant abiotic stress responses using the kanghan gene family
CN105629652B (zh) * 2016-03-17 2018-08-17 西安电子科技大学 一种基于自适应体素细分的光学断层成像方法
CN105695469B (zh) * 2016-04-14 2018-05-29 甘肃农业大学 马铃薯stu-miR9471及其应用
CN105925614A (zh) * 2016-05-23 2016-09-07 福建农林大学 一种快速抑制龙眼胚性愈伤组织中目标基因表达的方法
CN112852805B (zh) * 2019-11-28 2024-02-09 电子科技大学 水稻miRNA纯合致死突变体的制备方法
CN110982921B (zh) * 2019-12-13 2020-10-27 南京林业大学 春兰miR159a在加快植物生命周期中的应用
CN111304198B (zh) * 2019-12-13 2020-10-09 南京林业大学 春兰miR390b在控制植物营养器官发育中的应用
US20210363526A1 (en) * 2020-05-21 2021-11-25 University Of Kentucky Research Foundation Use of Non-Coding Nucleic Acid for Crop Improvement and Protection Against Microbes
EP4203677A1 (en) * 2020-08-26 2023-07-05 Vindara, Inc. Method and/or compositions for lettuce (lactuca sativa) breeding and/or varieties developed thereby
CN112094845B (zh) * 2020-09-27 2022-03-15 四川农业大学 一种改良植物农艺性状和抗性的核酸及其应用
CN113444741B (zh) * 2021-06-30 2022-05-20 西南大学 下调表达Bna-miR168a在改良油菜性状中应用

Family Cites Families (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643771A (en) 1980-05-19 1997-07-01 The Board Of Trustees Of The Leland Stanford Junior University Non-reverting live bacterial vaccines
US4407956A (en) 1981-03-13 1983-10-04 The Regents Of The University Of California Cloned cauliflower mosaic virus DNA as a plant vehicle
CA1192510A (en) 1981-05-27 1985-08-27 Lawrence E. Pelcher Rna plant virus vector or portion thereof, a method of construction thereof, and a method of producing a gene derived product therefrom
NL8200523A (nl) 1982-02-11 1983-09-01 Univ Leiden Werkwijze voor het in vitro transformeren van planteprotoplasten met plasmide-dna.
US4536475A (en) 1982-10-05 1985-08-20 Phytogen Plant vector
EP0320500B1 (en) 1983-01-13 2004-11-17 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Non-oncogenic ti plasmid vector system and recombinant DNA molecules for the introduction of expressible genes into plant cell genomes
EP0131623B2 (en) 1983-01-17 1999-07-28 Monsanto Company Chimeric genes suitable for expression in plant cells
US5352605A (en) 1983-01-17 1994-10-04 Monsanto Company Chimeric genes for transforming plant cells using viral promoters
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US5504200A (en) 1983-04-15 1996-04-02 Mycogen Plant Science, Inc. Plant gene expression
EP0160692A1 (en) 1983-11-03 1985-11-13 DE WET, Johannes Martenis Jacob Method for the transfer of exogenous genes in plants using pollen as a vector
US4897355A (en) 1985-01-07 1990-01-30 Syntex (U.S.A.) Inc. N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
US5420034A (en) 1986-07-31 1995-05-30 Calgene, Inc. Seed-specific transcriptional regulation
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DK162399C (da) 1986-01-28 1992-03-23 Danisco Fremgangsmaade til ekspression af gener i baelgplanteceller, dna-fragment, rekombineret dna-fragment samt plasmid til brug ved udoevelsen af fremgangsmaaden
US4975374A (en) 1986-03-18 1990-12-04 The General Hospital Corporation Expression of wild type and mutant glutamine synthetase in foreign hosts
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
IL84459A (en) 1986-12-05 1993-07-08 Agracetus Apparatus and method for the injection of carrier particles carrying genetic material into living cells
WO1989005859A1 (en) 1987-12-21 1989-06-29 The Upjohn Company Agrobacterium mediated transformation of germinating plant seeds
US5922602A (en) 1988-02-26 1999-07-13 Biosource Technologies, Inc. Cytoplasmic inhibition of gene expression
US5614395A (en) 1988-03-08 1997-03-25 Ciba-Geigy Corporation Chemically regulatable and anti-pathogenic DNA sequences and uses thereof
US5789214A (en) 1988-03-08 1998-08-04 Novartis Finance Corporation Method of inducing gene transcription in a plant
EP0333033A1 (en) 1988-03-09 1989-09-20 Meiji Seika Kaisha Ltd. Glutamine synthesis gene and glutamine synthetase
NZ228320A (en) 1988-03-29 1991-06-25 Du Pont Nucleic acid promoter fragments of the promoter region homologous to the em gene of wheat, dna constructs therefrom and plants thereof
GB8810120D0 (en) 1988-04-28 1988-06-02 Plant Genetic Systems Nv Transgenic nuclear male sterile plants
EP0419533A1 (en) 1988-06-01 1991-04-03 THE TEXAS A&M UNIVERSITY SYSTEM Method for transforming plants via the shoot apex
US5597718A (en) 1988-10-04 1997-01-28 Agracetus Genetically engineering cotton plants for altered fiber
DE3843628A1 (de) 1988-12-21 1990-07-05 Inst Genbiologische Forschung Wundinduzierbare und kartoffelknollenspezifische transkriptionale regulation
JP3046063B2 (ja) 1989-03-17 2000-05-29 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 遺伝子の発現の外部の調節
US5231020A (en) 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5106739A (en) 1989-04-18 1992-04-21 Calgene, Inc. CaMv 355 enhanced mannopine synthase promoter and method for using same
ZA902710B (en) 1989-05-22 1991-12-24 Univ Georgia Res Found Enzyme luminescence assay
EP0409625A1 (en) 1989-07-19 1991-01-23 Calgene, Inc. Fruit-specific transcriptional factors
ATE496135T1 (de) 1989-08-10 2011-02-15 Bayer Bioscience Nv Pflanzen mit modifizierten blüten
US5322783A (en) 1989-10-17 1994-06-21 Pioneer Hi-Bred International, Inc. Soybean transformation by microparticle bombardment
GB8923716D0 (en) 1989-10-20 1989-12-06 Ici Plc Dna,constructs,cells and plants derived therefrom
GB9005772D0 (en) 1990-03-14 1990-05-09 Cambridge Advanced Tech Plant promoter
DK0472712T3 (da) 1990-03-16 2002-01-14 Calgene Llc Sekvenser, der præferentielt eksprimeres i tidlig frøudvikling og dertil relaterede fremgangsmåder
US5264618A (en) 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5168064A (en) 1990-04-20 1992-12-01 The Regents Of The University Of California Endo-1,4-β-glucanase gene and its use in plants
GB9009307D0 (en) 1990-04-25 1990-06-20 Ici Plc Dna,constructs,cells and plant derived therefrom
US5451513A (en) 1990-05-01 1995-09-19 The State University of New Jersey Rutgers Method for stably transforming plastids of multicellular plants
WO1991017424A1 (en) 1990-05-03 1991-11-14 Vical, Inc. Intracellular delivery of biologically active substances by means of self-assembling lipid complexes
US5187267A (en) 1990-06-19 1993-02-16 Calgene, Inc. Plant proteins, promoters, coding sequences and use
ES2173077T3 (es) 1990-06-25 2002-10-16 Monsanto Technology Llc Plantas que toleran glifosato.
US5225341A (en) 1990-07-19 1993-07-06 The Regents Of The University Of California Biologically safe plant transformation system using a ds transposon
US5639949A (en) 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
US5633435A (en) 1990-08-31 1997-05-27 Monsanto Company Glyphosate-tolerant 5-enolpyruvylshikimate-3-phosphate synthases
MX9100993A (es) 1990-09-10 1992-05-04 Us Agriculture Secuencia de adn aislado y enzima acido 1-aminociclopropan-1-carboxilico sintasa,recombinante
EP0558676B1 (en) 1990-11-23 2000-04-19 Plant Genetic Systems, N.V. Process for transforming monocotyledonous plants
SE467358B (sv) 1990-12-21 1992-07-06 Amylogene Hb Genteknisk foeraendring av potatis foer bildning av staerkelse av amylopektintyp
SE467160B (sv) 1990-12-21 1992-06-01 Amylogene Hb Genetisk foeraendring av potatis foer bildning av staerkelse av amylostyp
GB9105420D0 (en) 1991-03-14 1991-05-01 Ici Plc Expression of genes in transgenic plants
GB9106713D0 (en) 1991-03-28 1991-05-15 Ici Plc Dna,dna constructs,cells and plants derived therefrom
EP0513884A1 (en) 1991-04-16 1992-11-19 Mogen International N.V. Male-sterile plants, methods for obtaining male-sterile plants and recombinant DNA for use therein
GB9109063D0 (en) 1991-04-26 1991-06-12 Ici Plc Modification of lignin synthesis in plants
CA2110169A1 (en) 1991-05-30 1992-12-10 Walter Van Der Eycken Nematode-responsive plant promoters
GB9112645D0 (en) 1991-06-12 1991-07-31 Cambridge Advanced Tech Modification of starch production
GB9114259D0 (en) 1991-07-02 1991-08-21 Ici Plc Plant derived enzyme and dna sequences
WO1993001290A1 (en) 1991-07-11 1993-01-21 International Flower Developments Pty. Ltd. Genetic sequences encoding flavonoid pathway enzymes and uses therefor
CA2114636C (en) 1991-08-01 2006-11-28 Jon Donson Recombinant plant viral nucleic acids
DK152291D0 (da) 1991-08-28 1991-08-28 Danisco Fremgangsmaade og kemiske forbindelser
GB9119279D0 (en) 1991-09-10 1991-10-23 Ici Plc Modification of lignin synthesis in plants
GB9121074D0 (en) 1991-10-03 1991-11-13 Ici Plc Dna,dna constructs,cells and plants derived therefrom
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
US5866777A (en) 1991-11-20 1999-02-02 Mogen International, N.V. Method for obtaining plants with reduced susceptibility to plant-parasitic nematodes
US5593874A (en) 1992-03-19 1997-01-14 Monsanto Company Enhanced expression in plants
WO1993018643A1 (en) 1992-03-24 1993-09-30 Rice Breeding Research Laboratories Process for reducing seed storage proteins and process for transforming plants
DK0637339T3 (da) 1992-04-13 2001-12-03 Syngenta Ltd DNA-konstruktioner og planter, hvori de er inkorporeret
US5428148A (en) 1992-04-24 1995-06-27 Beckman Instruments, Inc. N4 - acylated cytidinyl compounds useful in oligonucleotide synthesis
GB9210273D0 (en) 1992-05-13 1992-07-01 Ici Plc Dna
WO1994000977A1 (en) 1992-07-07 1994-01-20 Japan Tobacco Inc. Method of transforming monocotyledon
JPH07503376A (ja) 1992-07-30 1995-04-13 ケイヘーネ・エヌ・ベー Ｄｎａ構築物並びにそれから誘導される細胞及び植物
EP0665891A1 (en) 1992-10-15 1995-08-09 Mogen International N.V. Genetic moderation or restoration of plant phenotypes
ZA939767B (en) 1993-01-21 1994-09-14 Univ North Carolina State Nematode-resistant transgenic plants
JPH08506490A (ja) 1993-02-05 1996-07-16 モンサント・カンパニー 植物中の改変リノレン酸及びリノール酸含量
US5908973A (en) 1993-03-22 1999-06-01 Zeneca Limited DNA encoding fruit-ripening-related proteins, DNA constructs, cells and plants derived therefrom
EP0620281A3 (en) 1993-03-31 1995-05-03 Mitsubishi Corp Oilseed-producing oilseeds with modified amino and fatty acid compositions.
WO1994029465A1 (en) 1993-06-08 1994-12-22 Nunhems Zaden B.V. Process for generating male sterile plants
US6326527B1 (en) 1993-08-25 2001-12-04 Dekalb Genetics Corporation Method for altering the nutritional content of plant seed
DE69433809T2 (de) 1993-09-03 2005-06-16 Japan Tobacco Inc. Verfahren zur transformation von monocotyledonen mittels des schildes von unreifen embryonen
DE69432796T2 (de) 1993-09-09 2004-04-29 Bayer Cropscience Gmbh Kombination von dna-sequenzen, die die bildung von modifizierter stärke in pflanzenzellen und pflanzen ermöglicht, verfahren zur herstellung dieser pflanzen
GB9318927D0 (en) 1993-09-13 1993-10-27 Zeneca Ltd Regulation of senescence
US5470353A (en) 1993-10-20 1995-11-28 Hollister Incorporated Post-operative thermal blanket
GB9324707D0 (en) 1993-12-02 1994-01-19 Olsen Odd Arne Promoter
KR100386337B1 (ko) 1993-12-09 2004-03-24 토마스 제퍼슨 대학교 진핵세포에서부위-특이적돌연변이를위한화합물과그방법
US5576198A (en) 1993-12-14 1996-11-19 Calgene, Inc. Controlled expression of transgenic constructs in plant plastids
GB9403512D0 (en) 1994-02-24 1994-04-13 Olsen Odd Arne Promoter
US5545817A (en) 1994-03-11 1996-08-13 Calgene, Inc. Enhanced expression in a plant plastid
US5545818A (en) 1994-03-11 1996-08-13 Calgene Inc. Expression of Bacillus thuringiensis cry proteins in plant plastids
US5545366A (en) 1994-06-10 1996-08-13 Lust; Victor Molding arrangement to achieve short mold cycle time and method of molding
GB9421286D0 (en) 1994-10-21 1994-12-07 Danisco Promoter
US5877159A (en) 1995-05-03 1999-03-02 University Of Maryland At Baltimore Method for introducing and expressing genes in animal cells and live invasive bacterial vectors for use in the same
US5824538A (en) 1995-09-06 1998-10-20 The United States Of America As Represented By The Secretary Of The Army Shigella vector for delivering DNA to a mammalian cell
JPH11513256A (ja) 1995-10-06 1999-11-16 プラント ジエネテイツク システムズ エヌ．ブイ 種子粉砕
ATE333431T1 (de) 1995-10-17 2006-08-15 Inventio Ag Sicherheitseinrichtung für eine aufzugsgruppe
EP0771878A1 (en) 1995-10-31 1997-05-07 Plant Genetic Systems N.V. Plants with reduced glucosinolate content
US5773692A (en) 1995-12-12 1998-06-30 Her Majesty The Queen In Right Of Canada, As Represented By Agriculture And Agri-Food Canada Anti-sense RNA for CAB transcript to reduce chlorophyll content in plants
US5693512A (en) 1996-03-01 1997-12-02 The Ohio State Research Foundation Method for transforming plant tissue by sonication
CA2247980C (en) 1996-03-06 2005-05-31 Pal Maliga Plastid transformation in arabidopsis thaliana
AR006928A1 (es) 1996-05-01 1999-09-29 Pioneer Hi Bred Int Una molecula de adn aislada que codifica una proteina fluorescente verde como marcador rastreable para la transformacion de plantas, un metodo para laproduccion de plantas transgenicas, un vector de expresion, una planta transgenica y celulas de dichas plantas.
DE19619353A1 (de) 1996-05-14 1997-11-20 Bosch Gmbh Robert Verfahren zur Herstellung eines integriert optischen Wellenleiterbauteiles sowie Anordnung
EP2253708A1 (en) 1996-06-14 2010-11-24 E. I. du Pont de Nemours and Company Suppresion of specific classes of soybean seed protein genes
US6025192A (en) 1996-09-20 2000-02-15 Cold Spring Harbor Laboratory Modified retroviral vectors
US6255071B1 (en) 1996-09-20 2001-07-03 Cold Spring Harbor Laboratory Mammalian viral vectors and their uses
DE19644478A1 (de) 1996-10-25 1998-04-30 Basf Ag Blattspezifische Expression von Genen in transgenen Pflanzen
US5955361A (en) 1996-11-20 1999-09-21 Pioneer Hi-Bred International, Inc. P gene promoter constructs for floral-tissue preferred gene expression
EP0870836A1 (de) 1997-04-09 1998-10-14 IPK Gatersleben 2-Desoxyglucose-6-Phosphat (2-DOG-6-P) Phosphatase DNA-Sequenzen als Selektionsmarker in Pflanzen
US5977436A (en) 1997-04-09 1999-11-02 Rhone Poulenc Agrochimie Oleosin 5' regulatory region for the modification of plant seed lipid composition
US5929300A (en) 1997-07-15 1999-07-27 The United States Of America As Represented By The Secretary Of Agriculture Pollen-based transformation system using solid media
AR013269A1 (es) 1997-08-04 2000-12-13 Scras Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral
DE69836552T3 (de) 1997-09-30 2014-10-09 The Regents Of The University Of California Herstellung von proteinen in pflanzensamen
US5994624A (en) 1997-10-20 1999-11-30 Cotton Incorporated In planta method for the production of transgenic plants
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
CZ295108B6 (cs) 1998-03-20 2005-05-18 Benitec Australia Ltd Syntetický gen obsahující dispergovanou nebo cizorodou deoxyribonukleovou molekulu a genový konstrukt obsahující tento syntetický gen
EP3214177A3 (en) 1998-04-08 2017-11-22 Commonwealth Scientific and Industrial Research Organisation Methods and means for obtaining modified phenotypes
GB9827152D0 (en) 1998-07-03 1999-02-03 Devgen Nv Characterisation of gene function using double stranded rna inhibition
US6555732B1 (en) 1998-09-14 2003-04-29 Pioneer Hi-Bred International, Inc. Rac-like genes and methods of use
DE19852195C2 (de) 1998-11-04 2000-11-02 Inst Pflanzengenetik & Kultur Neue Expressionskassette zur Expression von beliebigen Genen in Pflanzensamen
WO2000044914A1 (en) 1999-01-28 2000-08-03 Medical College Of Georgia Research Institute, Inc. Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
DE19956568A1 (de) 1999-01-30 2000-08-17 Roland Kreutzer Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
WO2000049035A1 (en) 1999-02-19 2000-08-24 The General Hospital Corporation Gene silencing
EP2363478B1 (en) 1999-04-21 2019-07-24 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhibiting the function of polynucleotide sequences
WO2000068374A1 (en) 1999-05-10 2000-11-16 Syngenta Participations Ag Regulation of viral gene expression
US20020016216A1 (en) 1999-06-08 2002-02-07 Kenji Kobayashi Golf club
MXPA01013462A (es) 1999-07-09 2002-07-02 Wyeth Corp Metodos y composiciones para prevenir la formacion de arn aberrante durante la transcripcion de una secuencia plasmidica.
AU1086501A (en) 1999-10-15 2001-04-30 Carnegie Institution Of Washington Rna interference pathway genes as tools for targeted genetic interference
GB9927444D0 (en) 1999-11-19 2000-01-19 Cancer Res Campaign Tech Inhibiting gene expression
DE10100586C1 (de) 2001-01-09 2002-04-11 Ribopharma Ag Verfahren zur Hemmung der Expression eines Ziegens
DE10160151A1 (de) 2001-01-09 2003-06-26 Ribopharma Ag Verfahren zur Hemmung der Expression eines vorgegebenen Zielgens
WO2001038551A1 (en) 1999-11-29 2001-05-31 Cold Spring Harbor Laboratory Regulation of polycomb group gene expression for increasing seed size in plants
RU2164944C1 (ru) 1999-12-09 2001-04-10 Институт молекулярной биологии им. В.А. Энгельгардта РАН Способ изменения генетических свойств организма
AU2625501A (en) 1999-12-30 2001-07-16 Rutgers, The State University Of New Jersey Compositions and methods for gene silencing
IT1316982B1 (it) 2000-01-17 2003-05-26 Univ Roma Isolamento e caratterizzazione di un gene per il silenziamento genicoda n.crassa e suoi usi.
WO2005019453A2 (en) 2001-05-18 2005-03-03 Sirna Therapeutics, Inc. RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING CHEMICALLY MODIFIED SHORT INTERFERING NUCLEIC ACID (siNA)
WO2003070918A2 (en) 2002-02-20 2003-08-28 Ribozyme Pharmaceuticals, Incorporated Rna interference by modified short interfering nucleic acid
AU2001245793A1 (en) 2000-03-16 2001-09-24 Cold Spring Harbor Laboratory Methods and compositions for rna interference
WO2001070949A1 (en) 2000-03-17 2001-09-27 Benitec Australia Ltd Genetic silencing
AU2001260140A1 (en) 2000-03-22 2001-10-03 Avntis Pharma Deutschland Gmbh Nematodes as model organisms for the investigation of neurodegenerative diseases, in particular parkinsons disease, uses and methods for the discovery of substances and genes which can be used in the treatment of the above disease states and identification of a nematode gene.
GB0007268D0 (en) 2000-03-24 2000-05-17 Cyclacel Ltd Cell cycle progression proteins
DK1309726T4 (en) 2000-03-30 2019-01-28 Whitehead Inst Biomedical Res RNA Sequence-Specific Mediators of RNA Interference
CA2410947A1 (en) 2000-05-30 2001-12-06 Johnson & Johnson Research Pty Limited Methods for mediating gene suppresion by using factors that enhance rnai
CA2428438C (en) 2000-11-09 2012-09-25 Cenix Bioscience Gmbh Eukaryotic cell division genes and their use in diagnosis and treatment of proliferative diseases
KR100872437B1 (ko) 2000-12-01 2008-12-05 막스-플랑크-게젤샤프트 츄어 푀르더룽 데어 비쎈샤프텐 에.파우. Ｒｎａ 간섭을 매개하는 작은 ｒｎａ 분자
JP4210737B2 (ja) 2001-07-12 2009-01-21 ユニバーシティー オブ マサチューセッツ 遺伝子サイレンシングを仲介する低分子干渉リボ核酸のインビボにおける製造方法
WO2003008596A2 (de) 2001-07-13 2003-01-30 Sungene Gmbh & Co. Kgaa Expressionskassetten zur transgenen expression von selektionsmarkern
GB0201043D0 (en) 2002-01-17 2002-03-06 Swetree Genomics Ab Plants methods and means
EP3415625A1 (en) 2002-02-01 2018-12-19 Life Technologies Corporation Double-stranded oligonucleotides
DE10212892A1 (de) 2002-03-20 2003-10-09 Basf Plant Science Gmbh Konstrukte und Verfahren zur Regulation der Genexpression
US20040268441A1 (en) 2002-07-19 2004-12-30 University Of South Carolina Compositions and methods for the modulation of gene expression in plants
WO2004066183A2 (en) 2003-01-22 2004-08-05 European Molecular Biology Laboratory Microrna
WO2004085623A2 (en) 2003-03-24 2004-10-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education A compact synthetic expression vector comprising double-stranded dna molecules and methods of use thereof
US20090012016A1 (en) 2003-10-22 2009-01-08 Zissimos Mourelatos Short Interfering Rna and Micro-Rna Compounds and Methods of Designing, Making, and Using the Same
CA2543013A1 (en) 2003-10-23 2005-05-19 Sirna Therapeutics, Inc. Rna interference mediated inhibition of nogo and nogo receptor gene expression using short interfering nucleic acid (sina)
CA2543954C (en) 2003-10-27 2016-11-08 Rosetta Inpharmatics Llc Method of designing sirnas for gene silencing
CA2524565A1 (en) 2004-12-04 2006-06-04 Sungene Gmbh Expression cassettes for mesophyll- and/or epidermis-preferential expression in plants
EP1666599A3 (en) 2004-12-04 2006-07-12 SunGene GmbH Expression cassettes for mesophyll- and/or epidermis-preferential expression in plants
US20060200878A1 (en) * 2004-12-21 2006-09-07 Linda Lutfiyya Recombinant DNA constructs and methods for controlling gene expression
US8030473B2 (en) * 2005-01-07 2011-10-04 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Method to trigger RNA interference
US20070066521A1 (en) * 2005-04-13 2007-03-22 Fauquet Claude M Short RNA-binding proteins
US20070111227A1 (en) * 2005-07-28 2007-05-17 Green Pamela J Small regulatory RNAs and methods of use

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