[go: up one dir, main page]

IT1316982B1 - Isolamento e caratterizzazione di un gene per il silenziamento genicoda n.crassa e suoi usi. - Google Patents

Isolamento e caratterizzazione di un gene per il silenziamento genicoda n.crassa e suoi usi.

Info

Publication number
IT1316982B1
IT1316982B1 IT2000RM000021A ITRM20000021A IT1316982B1 IT 1316982 B1 IT1316982 B1 IT 1316982B1 IT 2000RM000021 A IT2000RM000021 A IT 2000RM000021A IT RM20000021 A ITRM20000021 A IT RM20000021A IT 1316982 B1 IT1316982 B1 IT 1316982B1
Authority
IT
Italy
Prior art keywords
gene
crassa
characterization
isolation
silence
Prior art date
Application number
IT2000RM000021A
Other languages
English (en)
Inventor
Carlo Cogoni
Giuseppe Macino
Caterina Catalanotto
Gianluca Azzalin
Original Assignee
Univ Roma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Roma filed Critical Univ Roma
Priority to IT2000RM000021A priority Critical patent/IT1316982B1/it
Publication of ITRM20000021A0 publication Critical patent/ITRM20000021A0/it
Priority to PCT/IT2001/000008 priority patent/WO2001053475A2/en
Priority to AU2001230498A priority patent/AU2001230498A1/en
Publication of ITRM20000021A1 publication Critical patent/ITRM20000021A1/it
Application granted granted Critical
Publication of IT1316982B1 publication Critical patent/IT1316982B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT2000RM000021A 2000-01-17 2000-01-17 Isolamento e caratterizzazione di un gene per il silenziamento genicoda n.crassa e suoi usi. IT1316982B1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT2000RM000021A IT1316982B1 (it) 2000-01-17 2000-01-17 Isolamento e caratterizzazione di un gene per il silenziamento genicoda n.crassa e suoi usi.
PCT/IT2001/000008 WO2001053475A2 (en) 2000-01-17 2001-01-12 Isolation and characterization of a n. crassa silencing gene and uses thereof
AU2001230498A AU2001230498A1 (en) 2000-01-17 2001-01-12 Isolation and characterization of a n. crassa silencing gene and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000RM000021A IT1316982B1 (it) 2000-01-17 2000-01-17 Isolamento e caratterizzazione di un gene per il silenziamento genicoda n.crassa e suoi usi.

Publications (3)

Publication Number Publication Date
ITRM20000021A0 ITRM20000021A0 (it) 2000-01-17
ITRM20000021A1 ITRM20000021A1 (it) 2001-07-17
IT1316982B1 true IT1316982B1 (it) 2003-05-26

Family

ID=11454345

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000RM000021A IT1316982B1 (it) 2000-01-17 2000-01-17 Isolamento e caratterizzazione di un gene per il silenziamento genicoda n.crassa e suoi usi.

Country Status (3)

Country Link
AU (1) AU2001230498A1 (it)
IT (1) IT1316982B1 (it)
WO (1) WO2001053475A2 (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8202979B2 (en) 2002-02-20 2012-06-19 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
US7109165B2 (en) 2001-05-18 2006-09-19 Sirna Therapeutics, Inc. Conjugates and compositions for cellular delivery
US20050148530A1 (en) 2002-02-20 2005-07-07 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US7517864B2 (en) 2001-05-18 2009-04-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
US9994853B2 (en) 2001-05-18 2018-06-12 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
US9657294B2 (en) 2002-02-20 2017-05-23 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
US9181551B2 (en) 2002-02-20 2015-11-10 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
AU2003207708A1 (en) 2002-02-20 2003-09-09 Sirna Therapeutics, Inc. Rna interference mediated inhibition of map kinase genes
ATE452188T1 (de) 2004-02-10 2010-01-15 Sirna Therapeutics Inc Rna-interferenz-vermittelte hemmung der genexpression unter verwendung multifunktioneller sina (short interfering nucleic acid)
GB0405659D0 (en) * 2004-03-12 2004-04-21 Horticulture Res Internat Altered expression in filamentous fungi
AU2005238034A1 (en) 2004-04-23 2005-11-10 The Trustees Of Columbia University In The City Of New York Inhibition of hairless protein mRNA
US10508277B2 (en) 2004-05-24 2019-12-17 Sirna Therapeutics, Inc. Chemically modified multifunctional short interfering nucleic acid molecules that mediate RNA interference
CN101268194A (zh) 2005-09-20 2008-09-17 巴斯福植物科学有限公司 使用ta-siRNA调控基因表达的方法
BRPI0809130A8 (pt) 2007-03-21 2021-11-03 Brookhaven Science Ass Llc Composições combinadas hairpin-antissenso e métodos para modulação da expressão
KR101605932B1 (ko) 2009-12-18 2016-03-24 노파르티스 아게 Ｈｓｆ1-관련 질환을 치료하기 위한 유기 조성물
BR112012019902A2 (pt) 2010-02-10 2019-09-24 Novartis Ag "método e compostos para o crescimento muscular"
US9260471B2 (en) 2010-10-29 2016-02-16 Sirna Therapeutics, Inc. RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA)

Also Published As

Publication number Publication date
ITRM20000021A0 (it) 2000-01-17
AU2001230498A1 (en) 2001-07-31
WO2001053475A2 (en) 2001-07-26
ITRM20000021A1 (it) 2001-07-17
WO2001053475A3 (en) 2002-02-21

Similar Documents

Publication Publication Date Title
IT1316982B1 (it) Isolamento e caratterizzazione di un gene per il silenziamento genicoda n.crassa e suoi usi.
ZA200304893B (en) Ether derivatives useful as inhibitors of PDE4 isozymes.
MXPA03000694A (es) Nuevo uso de los inhibidores de lipasa.
DE60216823D1 (de) Zwischenprodukten für die Herstellung von Pyridazinon Aldose Reductase Inhibitoren.
DK1686113T3 (da) Inhibitorer af aspartylprotease
HUP0402644A3 (en) Combination of cytochome p450 dependent protease inhibitors
NO20014169D0 (no) Isolasjonsventil
FI20002044A0 (fi) Comt-entsyymiä estäviä naftaleenijohdannaisia
HK1061700A1 (en) An assay for detecting inhibitors of the enzyme myeloperokidase
IT1302885B1 (it) Isolamento e caratterizzazione di un gene per il silenziamento genicoda n. crassa e suoi usi.
GB0030284D0 (en) Enzyme inhibitors
AU2002214038A1 (en) Inhibitors of transglutaminases
DE60119396D1 (de) Lager
IT1309304B1 (it) Metodo e dispositivo per il controllo dinamico di un oggetto lungo unpercorso .
EP1467978A4 (en) "COMPOUNDS THAT CONTAIN VACCINATES DRUG LIPASE, THEIR SYNTHESIS AND USE"
HUP0100920A3 (en) Substrate for sound isolation of floating floors
AU2002211892A1 (en) Deep grayscale etching of silicon
IT1311951B1 (it) Valvola per erogatori di autorespiratori subacquei.
GB0109278D0 (en) Enzyme inhibitors
ATE263229T1 (de) Enzymatischer vergrauungsinhibitor
ITTO991124A1 (it) Gruppo integrato di lavabo, bidet e tazza w.c. per ambienti di varie misure (universali).
SI1387893T1 (sl) Preizkus za detekcijo inhibitorjev encima mieloperoksidaze
IT1319921B1 (it) Dispositivo ancorante di fissaggio per lastre di rivestimenti esterni.
DE10104914B4 (de) Lager
TW481272U (en) Leakage-proof tester of keyboard