ZA200705899B - Non steroidal glucocorticoid receptor modulators - Google Patents
Non steroidal glucocorticoid receptor modulators Download PDFInfo
- Publication number
- ZA200705899B ZA200705899B ZA200705899A ZA200705899A ZA200705899B ZA 200705899 B ZA200705899 B ZA 200705899B ZA 200705899 A ZA200705899 A ZA 200705899A ZA 200705899 A ZA200705899 A ZA 200705899A ZA 200705899 B ZA200705899 B ZA 200705899B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- halogen
- optionally substituted
- cyano
- hexahydro
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05101086 | 2005-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200705899B true ZA200705899B (en) | 2008-07-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200705899A ZA200705899B (en) | 2005-02-14 | 2007-07-18 | Non steroidal glucocorticoid receptor modulators |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US8133885B2 (de) |
| EP (1) | EP1853601B1 (de) |
| JP (1) | JP4922950B2 (de) |
| KR (1) | KR101285454B1 (de) |
| CN (1) | CN101119995B (de) |
| AR (1) | AR054329A1 (de) |
| AT (1) | ATE422497T1 (de) |
| AU (1) | AU2006212192B2 (de) |
| BR (1) | BRPI0607341A2 (de) |
| CA (1) | CA2597748C (de) |
| CY (1) | CY1109038T1 (de) |
| DE (1) | DE602006005138D1 (de) |
| DK (1) | DK1853601T3 (de) |
| ES (1) | ES2321227T3 (de) |
| HR (1) | HRP20090161T1 (de) |
| IL (1) | IL184374A (de) |
| MX (1) | MX2007008786A (de) |
| MY (1) | MY147632A (de) |
| NO (1) | NO20073702L (de) |
| NZ (1) | NZ556469A (de) |
| PE (1) | PE20061037A1 (de) |
| PL (1) | PL1853601T3 (de) |
| PT (1) | PT1853601E (de) |
| RS (1) | RS50778B (de) |
| RU (1) | RU2409577C2 (de) |
| SI (1) | SI1853601T1 (de) |
| TW (1) | TWI370129B (de) |
| UA (1) | UA91352C2 (de) |
| WO (1) | WO2006084917A1 (de) |
| ZA (1) | ZA200705899B (de) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI297685B (en) | 2002-04-04 | 2008-06-11 | Organon Nv | Non-steroidal progesterone receptor modulators |
| EP2114970B1 (de) | 2007-02-02 | 2011-08-03 | Pfizer Products Inc. | Trizyklische verbindungen und deren verwendung als glucocorticoidrezeptormodulatoren |
| TW200914029A (en) * | 2007-05-07 | 2009-04-01 | Organon Nv | New progesterone receptor modulators |
| US8063037B2 (en) | 2007-05-07 | 2011-11-22 | N. V. Organon | Progesterone receptor modulators |
| EP2364146B1 (de) | 2008-11-07 | 2019-06-19 | University of Sheffield | Medikament und diagnoseverfahren |
| DK3350175T3 (da) * | 2015-09-15 | 2020-02-03 | Leo Pharma As | Ikke-steroidale glucocorticoidreceptormodulatorer til lokal lægemiddelafgivelse |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4054572A (en) | 1973-04-26 | 1977-10-18 | Akzona Incorporated | Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines |
| TWI297685B (en) * | 2002-04-04 | 2008-06-11 | Organon Nv | Non-steroidal progesterone receptor modulators |
| US7074806B2 (en) * | 2002-06-06 | 2006-07-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
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