ATE422497T1 - Nichtsteroide glucocorticoid-rezeptormodulatoren - Google Patents

Nichtsteroide glucocorticoid-rezeptormodulatoren

Info

Publication number: ATE422497T1
Authority: AT; Austria
Prior art keywords: nonsteroid; receptor modulators; glucocorticoid receptor; glucocorticoid; modulators
Prior art date: 2005-02-14

Application number

AT06708243T

Other languages

English (en)

Inventor

Ralf Plate

Guido Jenny Rudolf Zaman

Pedro Harold Han Hermkens

Christiaan Gerardus Johan Jans

Rogier Christian Buijsman

Man Adrianus De

Paolo Giovanni Martino Conti

Scott James Lusher

Willem Hendrik Abraham Dokter

Original Assignee

Organon Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-02-14

Filing date

2006-02-14

Publication date

2009-02-15

2006-02-14 Application filed by Organon Nv filed Critical Organon Nv

2009-02-15 Application granted granted Critical

2009-02-15 Publication of ATE422497T1 publication Critical patent/ATE422497T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Pain & Pain Management (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Steroid Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

AT06708243T 2005-02-14 2006-02-14 Nichtsteroide glucocorticoid-rezeptormodulatoren ATE422497T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP05101086		2005-02-14

Publications (1)

Publication Number	Publication Date
ATE422497T1 true ATE422497T1 (de)	2009-02-15

Family

ID=34938730

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06708243T ATE422497T1 (de)	2005-02-14	2006-02-14	Nichtsteroide glucocorticoid-rezeptormodulatoren

Country Status (30)

Country	Link
US (1)	US8133885B2 (de)
EP (1)	EP1853601B1 (de)
JP (1)	JP4922950B2 (de)
KR (1)	KR101285454B1 (de)
CN (1)	CN101119995B (de)
AR (1)	AR054329A1 (de)
AT (1)	ATE422497T1 (de)
AU (1)	AU2006212192B2 (de)
BR (1)	BRPI0607341A2 (de)
CA (1)	CA2597748C (de)
CY (1)	CY1109038T1 (de)
DE (1)	DE602006005138D1 (de)
DK (1)	DK1853601T3 (de)
ES (1)	ES2321227T3 (de)
HR (1)	HRP20090161T1 (de)
IL (1)	IL184374A (de)
MX (1)	MX2007008786A (de)
MY (1)	MY147632A (de)
NO (1)	NO20073702L (de)
NZ (1)	NZ556469A (de)
PE (1)	PE20061037A1 (de)
PL (1)	PL1853601T3 (de)
PT (1)	PT1853601E (de)
RS (1)	RS50778B (de)
RU (1)	RU2409577C2 (de)
SI (1)	SI1853601T1 (de)
TW (1)	TWI370129B (de)
UA (1)	UA91352C2 (de)
WO (1)	WO2006084917A1 (de)
ZA (1)	ZA200705899B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI297685B (en)	2002-04-04	2008-06-11	Organon Nv	Non-steroidal progesterone receptor modulators
MY153057A (en)	2007-02-02	2014-12-31	Pfizer Prod Inc	Tryclic compounds,compositions and methods
TW200914029A (en) *	2007-05-07	2009-04-01	Organon Nv	New progesterone receptor modulators
US8063037B2 (en)	2007-05-07	2011-11-22	N. V. Organon	Progesterone receptor modulators
WO2010052445A1 (en)	2008-11-07	2010-05-14	University Of Sheffield	Medicament and method of diagnosis
US10494363B2 (en) *	2015-09-15	2019-12-03	Leo Pharma A/S	Non-steroidal glucocorticoid receptor modulators for local drug delivery

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4054572A (en) *	1973-04-26	1977-10-18	Akzona Incorporated	Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines
TWI297685B (en) *	2002-04-04	2008-06-11	Organon Nv	Non-steroidal progesterone receptor modulators
US7074806B2 (en) *	2002-06-06	2006-07-11	Boehringer Ingelheim Pharmaceuticals, Inc.	Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof

2006
- 2006-02-08 TW TW095104232A patent/TWI370129B/zh not_active IP Right Cessation
- 2006-02-13 AR ARP060100496A patent/AR054329A1/es not_active Application Discontinuation
- 2006-02-13 PE PE2006000165A patent/PE20061037A1/es not_active Application Discontinuation
- 2006-02-14 CN CN2006800047247A patent/CN101119995B/zh not_active Expired - Fee Related
- 2006-02-14 MX MXMX07008786A patent/MX2007008786A/es active IP Right Grant
- 2006-02-14 AU AU2006212192A patent/AU2006212192B2/en not_active Ceased
- 2006-02-14 DE DE602006005138T patent/DE602006005138D1/de active Active
- 2006-02-14 MY MYPI20060600A patent/MY147632A/en unknown
- 2006-02-14 JP JP2007554580A patent/JP4922950B2/ja not_active Expired - Fee Related
- 2006-02-14 RU RU2007134226/04A patent/RU2409577C2/ru not_active IP Right Cessation
- 2006-02-14 SI SI200630260T patent/SI1853601T1/sl unknown
- 2006-02-14 RS RSP-2009/0118A patent/RS50778B/sr unknown
- 2006-02-14 EP EP06708243A patent/EP1853601B1/de active Active
- 2006-02-14 ES ES06708243T patent/ES2321227T3/es active Active
- 2006-02-14 NZ NZ556469A patent/NZ556469A/en not_active IP Right Cessation
- 2006-02-14 KR KR1020077020365A patent/KR101285454B1/ko not_active IP Right Cessation
- 2006-02-14 CA CA2597748A patent/CA2597748C/en not_active Expired - Fee Related
- 2006-02-14 PT PT06708243T patent/PT1853601E/pt unknown
- 2006-02-14 WO PCT/EP2006/050906 patent/WO2006084917A1/en active Application Filing
- 2006-02-14 DK DK06708243T patent/DK1853601T3/da active
- 2006-02-14 US US11/816,113 patent/US8133885B2/en not_active Expired - Fee Related
- 2006-02-14 AT AT06708243T patent/ATE422497T1/de active
- 2006-02-14 BR BRPI0607341-7A patent/BRPI0607341A2/pt not_active IP Right Cessation
- 2006-02-14 UA UAA200707948A patent/UA91352C2/ru unknown
- 2006-02-14 PL PL06708243T patent/PL1853601T3/pl unknown
2007
- 2007-07-03 IL IL184374A patent/IL184374A/en not_active IP Right Cessation
- 2007-07-18 NO NO20073702A patent/NO20073702L/no not_active Application Discontinuation
- 2007-07-18 ZA ZA200705899A patent/ZA200705899B/en unknown
2009
- 2009-03-17 HR HR20090161T patent/HRP20090161T1/xx unknown
- 2009-04-29 CY CY20091100472T patent/CY1109038T1/el unknown

Also Published As

Publication number	Publication date
KR101285454B1 (ko)	2013-07-15
TW200640923A (en)	2006-12-01
PE20061037A1 (es)	2006-10-26
AR054329A1 (es)	2007-06-20
RU2409577C2 (ru)	2011-01-20
CY1109038T1 (el)	2014-07-02
US8133885B2 (en)	2012-03-13
CN101119995A (zh)	2008-02-06
PL1853601T3 (pl)	2009-07-31
RS50778B (sr)	2010-08-31
CN101119995B (zh)	2012-01-25
EP1853601A1 (de)	2007-11-14
RU2007134226A (ru)	2009-03-20
MX2007008786A (es)	2007-08-03
AU2006212192A1 (en)	2006-08-17
SI1853601T1 (sl)	2009-06-30
DK1853601T3 (da)	2009-05-18
AU2006212192B2 (en)	2011-06-16
HRP20090161T1 (en)	2009-05-31
UA91352C2 (en)	2010-07-26
BRPI0607341A2 (pt)	2010-03-23
MY147632A (en)	2012-12-31
ES2321227T3 (es)	2009-06-03
NZ556469A (en)	2009-08-28
US20090062262A1 (en)	2009-03-05
ZA200705899B (en)	2008-07-30
CA2597748C (en)	2013-09-24
KR20070107750A (ko)	2007-11-07
PT1853601E (pt)	2009-04-09
JP4922950B2 (ja)	2012-04-25
CA2597748A1 (en)	2006-08-17
WO2006084917A1 (en)	2006-08-17
EP1853601B1 (de)	2009-02-11
IL184374A0 (en)	2007-10-31
TWI370129B (en)	2012-08-11
JP2008530056A (ja)	2008-08-07
IL184374A (en)	2012-02-29
DE602006005138D1 (de)	2009-03-26
NO20073702L (no)	2007-09-28

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ZA200803452B (en)	2009-10-28	Modulation of glucocorticoid receptor expression
DK2114970T3 (da)	2011-09-19	Tricykliske forbindelser og deres anvendelse som glucocorticoidreceptormodulatorer
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BRPI0813653A2 (pt)	2014-12-30	Compostos de imidazotiazol moduladores de sirtuína
BRPI0813651A2 (pt)	2014-12-30	Compostos de tiazolopiridina moduladores de sirtuína
DK1940797T3 (da)	2012-09-10	8-substituerede benzodiazepiner som toll-like receptor- modulatorer
EP2179061A4 (de)	2010-09-08	Toll-like rezeptor-modulatoren
DK2014652T3 (da)	2014-10-13	Aktiveringsmiddel til peroxisom-proliferator-aktiveret receptor
DK2262808T3 (da)	2013-11-04	Chemokinreceptormodulatorer
DE112008002590A5 (de)	2010-06-24	Mikroreaktor
DK2297100T3 (da)	2012-12-17	Tetrahydrocyclopenta[b]indol-androgenreceptor-modulatorer
NO20082179L (no)	2008-07-15	Konverteringsanordning
IL191766A0 (en)	2008-12-29	Gaba-b receptor modulators
IL191710A0 (en)	2009-09-22	Glucocorticoid receptor modulators as antiinflammatory agents
BRPI0822061A2 (pt)	2015-06-23	Moduladores do receptor canabinoide
DK2114888T3 (da)	2011-01-24	Tricykliske forbindelser og deres anvendelse som glu-cocorticoid-receptor-modulatorer
ATE422497T1 (de)	2009-02-15	Nichtsteroide glucocorticoid-rezeptormodulatoren
DE602006007035D1 (de)	2009-07-09	Ieses verwendende abgabevorrichtung
EP1915162A4 (de)	2009-08-26	Modulatoren
EP1751115A4 (de)	2010-10-20	Theramuteinmodulatoren
ZA200800690B (en)	2009-09-30	Non-steroidal progesterone receptor modulators
DK2066677T3 (da)	2010-11-08	Pyridooxazepinprogesteronreceptormodulatorer
DE602006020489D1 (de)	2011-04-14	Cb1-rezeptormodulatoren
BRPI0920825A2 (pt)	2015-12-22	modulador seletivo do receptor de estrogênio

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