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CY1109038T1 - Μη στεροειδεις ρυθμιστες υποδοχεα γλυκοκορτικοειδων - Google Patents

Μη στεροειδεις ρυθμιστες υποδοχεα γλυκοκορτικοειδων

Info

Publication number
CY1109038T1
CY1109038T1 CY20091100472T CY091100472T CY1109038T1 CY 1109038 T1 CY1109038 T1 CY 1109038T1 CY 20091100472 T CY20091100472 T CY 20091100472T CY 091100472 T CY091100472 T CY 091100472T CY 1109038 T1 CY1109038 T1 CY 1109038T1
Authority
CY
Cyprus
Prior art keywords
corticity
glucic
adjusters
steroid
receptors
Prior art date
Application number
CY20091100472T
Other languages
English (en)
Inventor
Ralf Plate
Guido Jenny Rudolf Zaman
Pedro Harold Han Hermkens
Christiaan Gerardus Johannes Maria Jans
Rogier Christian Buijsman
Man Adrianus Petrus Antonius De
Paolo Giovanni Martino Conti
Scott James Lusher
Willem Hendrik Abraham Dokter
Original Assignee
N.V. Organon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by N.V. Organon filed Critical N.V. Organon
Publication of CY1109038T1 publication Critical patent/CY1109038T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αφορά σε ενώσεις που έχουν το γενικό τύπο (I) ή ένα φαρμακευτικά αποδεκτό άλας τους. Σε αυτό τον τύπο :
CY20091100472T 2005-02-14 2009-04-29 Μη στεροειδεις ρυθμιστες υποδοχεα γλυκοκορτικοειδων CY1109038T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05101086 2005-02-14
EP06708243A EP1853601B1 (en) 2005-02-14 2006-02-14 Non steroidal glucocorticoid receptor modulators

Publications (1)

Publication Number Publication Date
CY1109038T1 true CY1109038T1 (el) 2014-07-02

Family

ID=34938730

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100472T CY1109038T1 (el) 2005-02-14 2009-04-29 Μη στεροειδεις ρυθμιστες υποδοχεα γλυκοκορτικοειδων

Country Status (30)

Country Link
US (1) US8133885B2 (el)
EP (1) EP1853601B1 (el)
JP (1) JP4922950B2 (el)
KR (1) KR101285454B1 (el)
CN (1) CN101119995B (el)
AR (1) AR054329A1 (el)
AT (1) ATE422497T1 (el)
AU (1) AU2006212192B2 (el)
BR (1) BRPI0607341A2 (el)
CA (1) CA2597748C (el)
CY (1) CY1109038T1 (el)
DE (1) DE602006005138D1 (el)
DK (1) DK1853601T3 (el)
ES (1) ES2321227T3 (el)
HR (1) HRP20090161T1 (el)
IL (1) IL184374A (el)
MX (1) MX2007008786A (el)
MY (1) MY147632A (el)
NO (1) NO20073702L (el)
NZ (1) NZ556469A (el)
PE (1) PE20061037A1 (el)
PL (1) PL1853601T3 (el)
PT (1) PT1853601E (el)
RS (1) RS50778B (el)
RU (1) RU2409577C2 (el)
SI (1) SI1853601T1 (el)
TW (1) TWI370129B (el)
UA (1) UA91352C2 (el)
WO (1) WO2006084917A1 (el)
ZA (1) ZA200705899B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI297685B (en) 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
MY153057A (en) 2007-02-02 2014-12-31 Pfizer Prod Inc Tryclic compounds,compositions and methods
TW200914029A (en) * 2007-05-07 2009-04-01 Organon Nv New progesterone receptor modulators
US8063037B2 (en) 2007-05-07 2011-11-22 N. V. Organon Progesterone receptor modulators
WO2010052445A1 (en) 2008-11-07 2010-05-14 University Of Sheffield Medicament and method of diagnosis
US10494363B2 (en) * 2015-09-15 2019-12-03 Leo Pharma A/S Non-steroidal glucocorticoid receptor modulators for local drug delivery

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4054572A (en) * 1973-04-26 1977-10-18 Akzona Incorporated Hexahydro pyridine [1,2d] dibenza [b,f] (1,4)-diazepines
TWI297685B (en) * 2002-04-04 2008-06-11 Organon Nv Non-steroidal progesterone receptor modulators
US7074806B2 (en) * 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof

Also Published As

Publication number Publication date
KR101285454B1 (ko) 2013-07-15
TW200640923A (en) 2006-12-01
PE20061037A1 (es) 2006-10-26
AR054329A1 (es) 2007-06-20
RU2409577C2 (ru) 2011-01-20
US8133885B2 (en) 2012-03-13
CN101119995A (zh) 2008-02-06
PL1853601T3 (pl) 2009-07-31
RS50778B (sr) 2010-08-31
CN101119995B (zh) 2012-01-25
EP1853601A1 (en) 2007-11-14
RU2007134226A (ru) 2009-03-20
MX2007008786A (es) 2007-08-03
AU2006212192A1 (en) 2006-08-17
SI1853601T1 (sl) 2009-06-30
DK1853601T3 (da) 2009-05-18
AU2006212192B2 (en) 2011-06-16
HRP20090161T1 (en) 2009-05-31
UA91352C2 (en) 2010-07-26
BRPI0607341A2 (pt) 2010-03-23
MY147632A (en) 2012-12-31
ES2321227T3 (es) 2009-06-03
NZ556469A (en) 2009-08-28
US20090062262A1 (en) 2009-03-05
ZA200705899B (en) 2008-07-30
CA2597748C (en) 2013-09-24
KR20070107750A (ko) 2007-11-07
PT1853601E (pt) 2009-04-09
JP4922950B2 (ja) 2012-04-25
CA2597748A1 (en) 2006-08-17
WO2006084917A1 (en) 2006-08-17
EP1853601B1 (en) 2009-02-11
IL184374A0 (en) 2007-10-31
TWI370129B (en) 2012-08-11
JP2008530056A (ja) 2008-08-07
IL184374A (en) 2012-02-29
DE602006005138D1 (de) 2009-03-26
NO20073702L (no) 2007-09-28
ATE422497T1 (de) 2009-02-15

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