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ZA200500693B - Oral pharmaceutical formualtion in the form of a plurality of microcapsules for prolonged release of active principle(s) with low solubility - Google Patents

Oral pharmaceutical formualtion in the form of a plurality of microcapsules for prolonged release of active principle(s) with low solubility

Info

Publication number
ZA200500693B
ZA200500693B ZA200500693A ZA200500693A ZA200500693B ZA 200500693 B ZA200500693 B ZA 200500693B ZA 200500693 A ZA200500693 A ZA 200500693A ZA 200500693 A ZA200500693 A ZA 200500693A ZA 200500693 B ZA200500693 B ZA 200500693B
Authority
ZA
South Africa
Prior art keywords
microcapsules
active principle
core
release
low solubility
Prior art date
Application number
ZA200500693A
Other languages
English (en)
Inventor
Florence Guimberteau
Catherine Castan
Remi Meyrueix
Original Assignee
Flamel Tech Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flamel Tech Sa filed Critical Flamel Tech Sa
Publication of ZA200500693B publication Critical patent/ZA200500693B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200500693A 2002-07-26 2005-01-24 Oral pharmaceutical formualtion in the form of a plurality of microcapsules for prolonged release of active principle(s) with low solubility ZA200500693B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0209532A FR2842736B1 (fr) 2002-07-26 2002-07-26 Formulation pharmaceutique orale sous forme d'une pluralite de microcapsules permettant la liberation prolongee de principe(s) actif(s) peu soluble(s)

Publications (1)

Publication Number Publication Date
ZA200500693B true ZA200500693B (en) 2006-07-26

Family

ID=30011529

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200500693A ZA200500693B (en) 2002-07-26 2005-01-24 Oral pharmaceutical formualtion in the form of a plurality of microcapsules for prolonged release of active principle(s) with low solubility

Country Status (17)

Country Link
US (1) US8652523B2 (xx)
EP (1) EP1524968B1 (xx)
JP (2) JP5430815B2 (xx)
KR (1) KR20050026515A (xx)
CN (1) CN1678295B (xx)
AT (1) ATE381927T1 (xx)
AU (1) AU2003269067B2 (xx)
BR (1) BR0312995A (xx)
CA (1) CA2493453C (xx)
DE (1) DE60318316T2 (xx)
ES (1) ES2298551T3 (xx)
FR (1) FR2842736B1 (xx)
IL (1) IL166383A0 (xx)
MX (1) MXPA05001077A (xx)
PT (1) PT1524968E (xx)
WO (1) WO2004010983A2 (xx)
ZA (1) ZA200500693B (xx)

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FR2882259A1 (fr) * 2005-02-21 2006-08-25 Flamel Technologies Sa Forme pharmaceutique orale multimicroparticulaire a liberation modifiee de losartan
FR2884145A1 (fr) * 2005-04-06 2006-10-13 Flamel Technologies Sa Forme pharmaceutique orale de losartan
FR2882260A1 (fr) * 2005-02-21 2006-08-25 Flamel Technologies Sa Forme pharmaceutique orale multimicroparticulaire a liberation modifiee d'antagonistes des recepteurs de l'angiotensine ii
WO2006087394A1 (fr) * 2005-02-21 2006-08-24 Flamel Technologies Forme pharmaceutique orale de losartan
FR2885526B1 (fr) * 2005-05-13 2007-07-27 Flamel Technologies Sa Medicament oral a base d'inhibiteur de pompe a protons
WO2006133733A1 (en) 2005-06-13 2006-12-21 Flamel Technologies Oral dosage form comprising an antimisuse system
US8652529B2 (en) 2005-11-10 2014-02-18 Flamel Technologies Anti-misuse microparticulate oral pharmaceutical form
CN102846585A (zh) 2006-03-28 2013-01-02 杰佛林制药公司 低剂量的双氯芬酸和β-环糊精的制剂
US9023400B2 (en) * 2006-05-24 2015-05-05 Flamel Technologies Prolonged-release multimicroparticulate oral pharmaceutical form
KR101814186B1 (ko) 2008-09-17 2018-03-14 키아스마 인코포레이티드 약제학적 조성물 및 연관된 투여방법
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FR2945945B1 (fr) * 2009-05-29 2011-07-29 Flamel Tech Sa Procede de preparation de particules creuses et leurs applications
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EP3253401B1 (en) 2015-02-03 2025-04-02 Amryt Endo, Inc. Treating acromegaly with oral octreotide
AU2016388308B2 (en) 2016-01-20 2022-08-04 Theravida, Inc. Methods and compositions for treating hyperhidrosis
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US12186296B1 (en) 2016-07-22 2025-01-07 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
UY37341A (es) 2016-07-22 2017-11-30 Flamel Ireland Ltd Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US11986451B1 (en) 2016-07-22 2024-05-21 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11504347B1 (en) 2016-07-22 2022-11-22 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11602512B1 (en) 2016-07-22 2023-03-14 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
WO2019126125A1 (en) 2017-12-20 2019-06-27 Purdue Pharma L.P. Abuse deterrent morphine sulfate dosage forms
WO2020130649A1 (ko) * 2018-12-19 2020-06-25 대화제약 주식회사 Glp-1 유사체를 포함하는 경구투여용 약제학적 조성물
US11400065B2 (en) 2019-03-01 2022-08-02 Flamel Ireland Limited Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal

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Also Published As

Publication number Publication date
KR20050026515A (ko) 2005-03-15
FR2842736B1 (fr) 2005-07-22
JP5430815B2 (ja) 2014-03-05
JP2006500332A (ja) 2006-01-05
US20060165809A1 (en) 2006-07-27
IL166383A0 (en) 2006-01-16
JP2014005289A (ja) 2014-01-16
AU2003269067A1 (en) 2004-02-16
CN1678295A (zh) 2005-10-05
CN1678295B (zh) 2010-04-28
PT1524968E (pt) 2008-03-13
DE60318316D1 (de) 2008-02-07
DE60318316T2 (de) 2008-12-11
MXPA05001077A (es) 2005-06-06
FR2842736A1 (fr) 2004-01-30
EP1524968A2 (fr) 2005-04-27
AU2003269067B2 (en) 2009-01-08
WO2004010983A2 (fr) 2004-02-05
CA2493453C (fr) 2012-05-22
CA2493453A1 (fr) 2004-02-05
EP1524968B1 (fr) 2007-12-26
US8652523B2 (en) 2014-02-18
ES2298551T3 (es) 2008-05-16
ATE381927T1 (de) 2008-01-15
BR0312995A (pt) 2005-06-28
WO2004010983A3 (fr) 2004-04-08

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