[go: up one dir, main page]

ZA200303794B - Heterocyclylalkyl piperidine derivatives, their preparation and compositions containing same. - Google Patents

Heterocyclylalkyl piperidine derivatives, their preparation and compositions containing same.

Info

Publication number
ZA200303794B
ZA200303794B ZA200303794A ZA200303794A ZA200303794B ZA 200303794 B ZA200303794 B ZA 200303794B ZA 200303794 A ZA200303794 A ZA 200303794A ZA 200303794 A ZA200303794 A ZA 200303794A ZA 200303794 B ZA200303794 B ZA 200303794B
Authority
ZA
South Africa
Prior art keywords
preparation
compositions containing
containing same
piperidine derivatives
heterocyclylalkyl piperidine
Prior art date
Application number
ZA200303794A
Other languages
English (en)
Inventor
Eric Bacque
Youssef El-Ahmad
Philippe Hubert
Serge Mignani
Michel Tabart
Jean-Christophe Carry
Michel Evers
Jean-Luc Malleron
Guy Pantel
Fabrice Viviani
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of ZA200303794B publication Critical patent/ZA200303794B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA200303794A 2000-11-15 2003-05-15 Heterocyclylalkyl piperidine derivatives, their preparation and compositions containing same. ZA200303794B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0014738A FR2816618B1 (fr) 2000-11-15 2000-11-15 Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent

Publications (1)

Publication Number Publication Date
ZA200303794B true ZA200303794B (en) 2004-06-29

Family

ID=8856503

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200303794A ZA200303794B (en) 2000-11-15 2003-05-15 Heterocyclylalkyl piperidine derivatives, their preparation and compositions containing same.

Country Status (28)

Country Link
EP (2) EP1337529B1 (bg)
JP (1) JP2004514661A (bg)
KR (1) KR100849608B1 (bg)
CN (1) CN1483031A (bg)
AR (1) AR034006A1 (bg)
AT (1) ATE337311T1 (bg)
AU (2) AU2002218365B2 (bg)
BG (1) BG107793A (bg)
BR (1) BR0115312A (bg)
CA (1) CA2429311A1 (bg)
CZ (1) CZ20031316A3 (bg)
DE (1) DE60122567T2 (bg)
DK (1) DK1337529T3 (bg)
EA (1) EA200300568A1 (bg)
EE (1) EE200300207A (bg)
ES (1) ES2271119T3 (bg)
FR (1) FR2816618B1 (bg)
HR (1) HRP20030379A2 (bg)
HU (1) HUP0303758A3 (bg)
IL (1) IL155841A0 (bg)
NO (2) NO20032187L (bg)
PL (1) PL363004A1 (bg)
PT (1) PT1337529E (bg)
SK (1) SK5822003A3 (bg)
TN (1) TNSN01160A1 (bg)
WO (1) WO2002040474A2 (bg)
YU (1) YU46803A (bg)
ZA (1) ZA200303794B (bg)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE348826T1 (de) 2000-07-26 2007-01-15 Smithkline Beecham Plc Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
JP4445753B2 (ja) 2002-01-29 2010-04-07 グラクソ グループ リミテッド アミノピペリジン誘導体
JP4508650B2 (ja) 2002-01-29 2010-07-21 グラクソ グループ リミテッド アミノピペリジン化合物、当該化合物の製法および当該化合物を含有する医薬組成物
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
AR040335A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto
FR2842807A1 (fr) * 2002-07-23 2004-01-30 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, procede et intermediaires de preparation et compositions les renfermant
GB0217294D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicaments
FR2844268B1 (fr) 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
FR2844270B1 (fr) * 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
DE10256405A1 (de) * 2002-12-02 2004-06-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen, die Topoisomerase IV inhibieren
ATE479683T1 (de) 2002-11-05 2010-09-15 Glaxo Group Ltd Antibakterielle mittel
EP1560821B8 (en) 2002-11-05 2010-05-19 Glaxo Group Limited Antibacterial agents
WO2004050036A2 (en) 2002-12-04 2004-06-17 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
FR2852954B1 (fr) * 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
US7232833B2 (en) 2003-03-28 2007-06-19 Novexel 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
FR2862301B1 (fr) * 2003-11-17 2007-12-21 Aventis Pharma Sa Nouveau procede de preparation de quinoleines 3-fluorees
FR2867472B1 (fr) * 2004-03-12 2008-07-18 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
US7709472B2 (en) 2005-01-25 2010-05-04 Glaxo Group Limited Antibacterial agents
US7648980B2 (en) 2005-01-25 2010-01-19 Glaxo Group Limited Antibacterial agents
JP2008528588A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
EP1846417A4 (en) 2005-01-25 2009-12-23 Glaxo Group Ltd ANTIBACTERIAL ACTIVE SUBSTANCES
BRPI0607404A2 (pt) 2005-03-01 2009-09-01 Wyeth Corp compostos de cinolina e seu uso como moduladores de receptor de x hepático
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP1981881B1 (en) 2006-01-26 2011-12-07 Actelion Pharmaceuticals Ltd. Tetrahydropyrane antibiotics
DE602007009205D1 (de) 2006-04-06 2010-10-28 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
EP2167494B1 (en) 2007-06-15 2011-08-17 Actelion Pharmaceuticals Ltd. 3-amino-6-(1-amino-ethyl)-tetrahydropyran derivatives
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
JP2012505866A (ja) 2008-10-17 2012-03-08 グラクソ グループ リミテッド 抗菌剤として使用される三環式窒素化合物
WO2010081874A1 (en) 2009-01-15 2010-07-22 Glaxo Group Limited Naphthyridin-2 (1 h)-one compounds useful as antibacterials
ES2893473T3 (es) * 2012-08-15 2022-02-09 Glaxo Group Ltd Proceso químico
TW201618779A (zh) 2014-08-22 2016-06-01 葛蘭素史克智慧財產發展有限公司 方法
WO2016138988A1 (en) * 2015-03-02 2016-09-09 University Of Copenhagen Piperazine inhibitors of bacterial gyrase and topoisomerase iv
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908031A (nl) 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
JPH0239546A (ja) 1988-07-29 1990-02-08 Origin Electric Co Ltd 混成集積回路の製造方法
NZ232091A (en) 1989-01-16 1990-12-21 Bellon Labor Sa Roger 7-fluoro-8-(piperazin-1-yl)-4-oxo-1,4-dihydro-benzo(b)(1,8)naphthyridine-3-carboxylic acid derivatives, preparation and pharmaceutical compositions thereof
AU2717899A (en) * 1998-01-26 1999-08-09 Smithkline Beecham Plc Quinoline derivatives as antibacterials
JP2002535323A (ja) * 1999-01-20 2002-10-22 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー プロテインキナーゼ阻害剤としてのピペリジニルキノリン
FR2852954B1 (fr) * 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
YU46803A (sh) 2006-05-25
TNSN01160A1 (fr) 2005-11-10
HUP0303758A2 (hu) 2004-03-01
IL155841A0 (en) 2003-12-23
ATE337311T1 (de) 2006-09-15
BG107793A (bg) 2004-08-31
NO20072142L (no) 2007-04-25
JP2004514661A (ja) 2004-05-20
SK5822003A3 (en) 2004-06-08
EE200300207A (et) 2003-08-15
EP1695964A1 (fr) 2006-08-30
WO2002040474A2 (fr) 2002-05-23
FR2816618B1 (fr) 2002-12-27
HRP20030379A2 (en) 2005-04-30
AR034006A1 (es) 2004-01-21
AU2002218365B2 (en) 2007-07-05
EP1337529A2 (fr) 2003-08-27
DK1337529T3 (da) 2006-12-18
KR100849608B1 (ko) 2008-07-31
KR20030060934A (ko) 2003-07-16
HUP0303758A3 (en) 2009-08-28
AU1836502A (en) 2002-05-27
ES2271119T3 (es) 2007-04-16
EP1337529B1 (fr) 2006-08-23
NO20032187D0 (no) 2003-05-14
CN1483031A (zh) 2004-03-17
NO20032187L (no) 2003-06-26
CA2429311A1 (en) 2002-05-23
PT1337529E (pt) 2006-12-29
FR2816618A1 (fr) 2002-05-17
CZ20031316A3 (cs) 2003-10-15
BR0115312A (pt) 2003-09-23
DE60122567T2 (de) 2007-08-23
DE60122567D1 (de) 2006-10-05
EA200300568A1 (ru) 2003-12-25
WO2002040474A3 (fr) 2002-10-31
PL363004A1 (en) 2004-11-15

Similar Documents

Publication Publication Date Title
ZA200303794B (en) Heterocyclylalkyl piperidine derivatives, their preparation and compositions containing same.
ZA200206905B (en) Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same.
IL151209A0 (en) Pharmaceutical compositions containing 3-aminoazetidine derivatives, novel derivatives and their preparation
HUP0303835A3 (en) Anti-allergic piperidine compounds, their use and pharmaceutical compositions containing them
HUP0400837A3 (en) 2-phenyl-thiazole derivatives, their use and pharmaceutical compositions containing them
HUP0301573A3 (en) Substituted arylpyrazines, pharmaceutical compositions containing them and their use
HUP0204474A3 (en) 1h-imidazopyridine derivatives, pharmaceutical compositions containing them and their use
HUP0400636A3 (en) Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and preparation thereof
HUP0204514A3 (en) Pyridinylimidazoles, pharmaceutical compositions containing them and their use
AU2001237526A1 (en) Pharmaceutical compositions containing 3-amino-azetidine derivatives, novel derivatives and preparation thereof
ZA200003998B (en) Pharmaceutical compositions.
MXPA03000771A (es) Nuevas composiciones farmaceuticas.
AU2001237525A1 (en) Azetidine derivatives, preparation thereof and pharmaceutical compositions containing same
HUP0302959A3 (en) Non-imidazole aryloxyalkylamines, pharmaceutical compositions containing them and their use
MXPA03007848A (es) Derivados de quinolil propil piperidina, su preparacion y las composiciones que los contienen.
HUP0400967A3 (en) Substituted 2-anilino-benzimidazoles, their use and pharmaceutical compositions containing them
HUP0400551A2 (en) Piperazine derivatives, their preparation and pharmaceutical compositions containing them
AU2002253219A1 (en) Quinolyl propyl piperidine derivatives, the preparation thereof and compositions containing same
ZA200210359B (en) Pharmaceutical compositions.
ZA200110150B (en) Streptogramin derivatives, preparation and compositions containing them.
PL356911A1 (en) Novel heterocyclic derivatives, preparation method and pharmaceutical compositions containing same
IL154240A0 (en) 4-pyrimidinamine derivatives, pharmaceutical compositions and related methods
MXPA03002105A (es) Composiciones farmaceuticas.
HK1060129A1 (en) Novel piperidinecarboxamide derivatives, method f or preparing same and pharmaceutical compositions containing same.
HK1052168A1 (en) N-deacetylthiocolchincine derivatives and pharmaceutical compositions containing them.