ZA200204960B - Hydrogel-driven drug dosage form. - Google Patents

Hydrogel-driven drug dosage form. Download PDF

Info

Publication number: ZA200204960B
Authority: ZA; South Africa
Prior art keywords: drug; water; dosage form; core; coating
Prior art date: 1999-12-23

Application number

ZA200204960A

Other languages

English (en)

Inventor

Appel Leah Elizabeth

Beyerinck Ronald Arthur

Chidlaw Mark Brian

Curatolo William John

Friesen Dwayne Thomas

Smith Kelly Lincoln

Thombre Avinash Govind

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-23

Filing date

2002-06-20

Publication date

2003-10-02

2002-06-20 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2003-10-02 Publication of ZA200204960B publication Critical patent/ZA200204960B/en

Links

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239000002552 dosage form Substances 0.000 title claims description 184
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238000000576 coating method Methods 0.000 claims description 203
239000011248 coating agent Substances 0.000 claims description 174
239000003795 chemical substances by application Substances 0.000 claims description 145
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NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
229960001790 sodium citrate Drugs 0.000 description 1
235000011083 sodium citrates Nutrition 0.000 description 1
AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
235000019333 sodium laurylsulphate Nutrition 0.000 description 1
RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 1
229940045902 sodium stearyl fumarate Drugs 0.000 description 1
229910052938 sodium sulfate Inorganic materials 0.000 description 1
235000011152 sodium sulphate Nutrition 0.000 description 1
235000010265 sodium sulphite Nutrition 0.000 description 1
238000007711 solidification Methods 0.000 description 1
230000008023 solidification Effects 0.000 description 1
239000002195 soluble material Substances 0.000 description 1
238000000638 solvent extraction Methods 0.000 description 1
235000011076 sorbitan monostearate Nutrition 0.000 description 1
239000001587 sorbitan monostearate Substances 0.000 description 1
229940035048 sorbitan monostearate Drugs 0.000 description 1
229960001294 spiramycin Drugs 0.000 description 1
235000019372 spiramycin Nutrition 0.000 description 1
229930191512 spiramycin Natural products 0.000 description 1
LXMSZDCAJNLERA-ZHYRCANASA-N spironolactone Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)SC(=O)C)C[C@@]21CCC(=O)O1 LXMSZDCAJNLERA-ZHYRCANASA-N 0.000 description 1
229960002256 spironolactone Drugs 0.000 description 1
238000001694 spray drying Methods 0.000 description 1
229910001220 stainless steel Inorganic materials 0.000 description 1
239000010935 stainless steel Substances 0.000 description 1
239000008117 stearic acid Substances 0.000 description 1
230000003637 steroidlike Effects 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
150000003460 sulfonic acids Chemical class 0.000 description 1
229960004940 sulpiride Drugs 0.000 description 1
239000000829 suppository Substances 0.000 description 1
230000009747 swallowing Effects 0.000 description 1
230000002522 swelling effect Effects 0.000 description 1
239000000454 talc Substances 0.000 description 1
229910052623 talc Inorganic materials 0.000 description 1
LXIKEPCNDFVJKC-QXMHVHEDSA-N tenidap Chemical compound C12=CC(Cl)=CC=C2N(C(=O)N)C(=O)\C1=C(/O)C1=CC=CS1 LXIKEPCNDFVJKC-QXMHVHEDSA-N 0.000 description 1
229960003676 tenidap Drugs 0.000 description 1
229960000580 terconazole Drugs 0.000 description 1
IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
RBTVSNLYYIMMKS-UHFFFAOYSA-N tert-butyl 3-aminoazetidine-1-carboxylate;hydrochloride Chemical compound Cl.CC(C)(C)OC(=O)N1CC(N)C1 RBTVSNLYYIMMKS-UHFFFAOYSA-N 0.000 description 1
229960003604 testosterone Drugs 0.000 description 1
229940072172 tetracycline antibiotic Drugs 0.000 description 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
239000004308 thiabendazole Substances 0.000 description 1
235000010296 thiabendazole Nutrition 0.000 description 1
229960004546 thiabendazole Drugs 0.000 description 1
WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 description 1
AYEKOFBPNLCAJY-UHFFFAOYSA-O thiamine pyrophosphate Chemical compound CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N AYEKOFBPNLCAJY-UHFFFAOYSA-O 0.000 description 1
229960004605 timolol Drugs 0.000 description 1
229960005013 tiotixene Drugs 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
JOFWLTCLBGQGBO-UHFFFAOYSA-N triazolam Chemical compound C12=CC(Cl)=CC=C2N2C(C)=NN=C2CN=C1C1=CC=CC=C1Cl JOFWLTCLBGQGBO-UHFFFAOYSA-N 0.000 description 1
229960003386 triazolam Drugs 0.000 description 1
229960002906 trimazosin Drugs 0.000 description 1
YNZXWQJZEDLQEG-UHFFFAOYSA-N trimazosin Chemical compound N1=C2C(OC)=C(OC)C(OC)=CC2=C(N)N=C1N1CCN(C(=O)OCC(C)(C)O)CC1 YNZXWQJZEDLQEG-UHFFFAOYSA-N 0.000 description 1
229960005041 troleandomycin Drugs 0.000 description 1
LQCLVBQBTUVCEQ-QTFUVMRISA-N troleandomycin Chemical compound O1[C@@H](C)[C@H](OC(C)=O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](C)C(=O)O[C@H](C)[C@H](C)[C@H](OC(C)=O)[C@@H](C)C(=O)[C@@]2(OC2)C[C@H](C)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)OC(C)=O)[C@H]1C LQCLVBQBTUVCEQ-QTFUVMRISA-N 0.000 description 1
229940124549 vasodilator Drugs 0.000 description 1
239000003071 vasodilator agent Substances 0.000 description 1
PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 description 1
229960004688 venlafaxine Drugs 0.000 description 1
229940100050 virazole Drugs 0.000 description 1
235000019165 vitamin E Nutrition 0.000 description 1
229940046009 vitamin E Drugs 0.000 description 1
239000011709 vitamin E Substances 0.000 description 1
150000003722 vitamin derivatives Chemical class 0.000 description 1
BCEHBSKCWLPMDN-MGPLVRAMSA-N voriconazole Chemical compound C1([C@H](C)[C@](O)(CN2N=CN=C2)C=2C(=CC(F)=CC=2)F)=NC=NC=C1F BCEHBSKCWLPMDN-MGPLVRAMSA-N 0.000 description 1
229960004740 voriconazole Drugs 0.000 description 1
239000003643 water by type Substances 0.000 description 1
239000000230 xanthan gum Substances 0.000 description 1
235000010493 xanthan gum Nutrition 0.000 description 1
229920001285 xanthan gum Polymers 0.000 description 1
229940082509 xanthan gum Drugs 0.000 description 1
XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Gynecology & Obstetrics (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

ZA200204960A 1999-12-23 2002-06-20 Hydrogel-driven drug dosage form. ZA200204960B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US17196899P	1999-12-23	1999-12-23

Publications (1)

Publication Number	Publication Date
ZA200204960B true ZA200204960B (en)	2003-10-02

Family

ID=22625827

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200204960A ZA200204960B (en)	1999-12-23	2002-06-20	Hydrogel-driven drug dosage form.

Country Status (42)

Country	Link
US (3)	US20020015731A1 (fr)
EP (2)	EP1242055B1 (fr)
JP (1)	JP4100910B2 (fr)
KR (1)	KR100523127B1 (fr)
CN (1)	CN1402632A (fr)
AP (1)	AP2002002553A0 (fr)
AR (1)	AR027091A1 (fr)
AT (1)	ATE392890T1 (fr)
AU (1)	AU783685B2 (fr)
BG (1)	BG106865A (fr)
BR (1)	BR0016708A (fr)
CA (1)	CA2395333C (fr)
CR (1)	CR6656A (fr)
CZ (1)	CZ20022046A3 (fr)
DE (1)	DE60038698T2 (fr)
DK (1)	DK1242055T3 (fr)
DZ (1)	DZ3228A1 (fr)
EA (1)	EA004370B1 (fr)
EE (1)	EE200200361A (fr)
ES (1)	ES2302705T3 (fr)
GE (1)	GEP20043334B (fr)
GT (1)	GT200000222A (fr)
HU (1)	HUP0301242A3 (fr)
IL (1)	IL149224A0 (fr)
IS (1)	IS6340A (fr)
MA (1)	MA26859A1 (fr)
MX (1)	MXPA02006328A (fr)
NO (1)	NO20022970L (fr)
NZ (1)	NZ518281A (fr)
OA (1)	OA12128A (fr)
PA (1)	PA8509001A1 (fr)
PE (1)	PE20010985A1 (fr)
PL (1)	PL357535A1 (fr)
PT (1)	PT1242055E (fr)
SI (1)	SI1242055T1 (fr)
SK (1)	SK8572002A3 (fr)
SV (1)	SV2002000250A (fr)
TN (1)	TNSN00253A1 (fr)
TR (1)	TR200201646T2 (fr)
WO (1)	WO2001047500A1 (fr)
YU (1)	YU35302A (fr)
ZA (1)	ZA200204960B (fr)

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2000
- 2000-12-20 AP APAP/P/2002/002553A patent/AP2002002553A0/en unknown
- 2000-12-20 YU YU35302A patent/YU35302A/sh unknown
- 2000-12-20 EP EP00983435A patent/EP1242055B1/fr not_active Expired - Lifetime
- 2000-12-20 GE GE4830A patent/GEP20043334B/en unknown
- 2000-12-20 IL IL14922400A patent/IL149224A0/xx unknown
- 2000-12-20 PT PT00983435T patent/PT1242055E/pt unknown
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- 2000-12-20 JP JP2001548095A patent/JP4100910B2/ja not_active Expired - Fee Related
- 2000-12-20 CZ CZ20022046A patent/CZ20022046A3/cs unknown
- 2000-12-20 ES ES00983435T patent/ES2302705T3/es not_active Expired - Lifetime
- 2000-12-20 DE DE60038698T patent/DE60038698T2/de not_active Expired - Lifetime
- 2000-12-20 EA EA200200595A patent/EA004370B1/ru not_active IP Right Cessation
- 2000-12-20 US US09/745,095 patent/US20020015731A1/en not_active Abandoned
- 2000-12-20 MX MXPA02006328A patent/MXPA02006328A/es active IP Right Grant
- 2000-12-20 CA CA002395333A patent/CA2395333C/fr not_active Expired - Fee Related
- 2000-12-20 CN CN00816441A patent/CN1402632A/zh active Pending
- 2000-12-20 WO PCT/IB2000/001920 patent/WO2001047500A1/fr active IP Right Grant
- 2000-12-20 KR KR10-2002-7008223A patent/KR100523127B1/ko not_active IP Right Cessation
- 2000-12-20 DK DK00983435T patent/DK1242055T3/da active
- 2000-12-20 EP EP08154885A patent/EP1967185A1/fr not_active Withdrawn
- 2000-12-20 AU AU20189/01A patent/AU783685B2/en not_active Ceased
- 2000-12-20 HU HU0301242A patent/HUP0301242A3/hu unknown
- 2000-12-20 BR BR0016708-8A patent/BR0016708A/pt not_active Application Discontinuation
- 2000-12-20 TR TR2002/01646T patent/TR200201646T2/xx unknown
- 2000-12-20 DZ DZ003228A patent/DZ3228A1/fr active
- 2000-12-20 SI SI200030997T patent/SI1242055T1/sl unknown
- 2000-12-20 OA OA1200200195A patent/OA12128A/en unknown
- 2000-12-20 AT AT00983435T patent/ATE392890T1/de not_active IP Right Cessation
- 2000-12-20 PL PL00357535A patent/PL357535A1/xx not_active Application Discontinuation
- 2000-12-20 NZ NZ518281A patent/NZ518281A/en unknown
- 2000-12-20 SK SK857-2002A patent/SK8572002A3/sk unknown
- 2000-12-21 GT GT200000222A patent/GT200000222A/es unknown
- 2000-12-22 PE PE2000001391A patent/PE20010985A1/es not_active Application Discontinuation
- 2000-12-22 SV SV2000000250A patent/SV2002000250A/es unknown
- 2000-12-22 TN TNTNSN00253A patent/TNSN00253A1/fr unknown
- 2000-12-22 PA PA20008509001A patent/PA8509001A1/es unknown
- 2000-12-22 AR ARP000106897A patent/AR027091A1/es unknown
2002
- 2002-04-12 IS IS6340A patent/IS6340A/is unknown
- 2002-06-04 CR CR6656A patent/CR6656A/es unknown
- 2002-06-18 MA MA26695A patent/MA26859A1/fr unknown
- 2002-06-20 ZA ZA200204960A patent/ZA200204960B/en unknown
- 2002-06-20 NO NO20022970A patent/NO20022970L/no not_active Application Discontinuation
- 2002-06-24 BG BG106865A patent/BG106865A/bg unknown
2006
- 2006-12-14 US US11/610,603 patent/US20070087057A1/en not_active Abandoned
2010
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Also Published As

Publication number	Publication date
NO20022970D0 (no)	2002-06-20
EE200200361A (et)	2003-10-15
DK1242055T3 (da)	2008-07-21
PT1242055E (pt)	2008-07-02
OA12128A (en)	2006-05-05
YU35302A (sh)	2005-03-15
SV2002000250A (es)	2002-02-05
IL149224A0 (en)	2002-11-10
AU2018901A (en)	2001-07-09
CN1402632A (zh)	2003-03-12
US20070087057A1 (en)	2007-04-19
EP1242055A1 (fr)	2002-09-25
ATE392890T1 (de)	2008-05-15
TNSN00253A1 (fr)	2002-05-30
MA26859A1 (fr)	2004-12-20
JP4100910B2 (ja)	2008-06-11
AP2002002553A0 (en)	2002-06-30
DZ3228A1 (fr)	2001-07-05
KR20020070330A (ko)	2002-09-05
EA004370B1 (ru)	2004-04-29
PA8509001A1 (es)	2002-02-21
US20110182947A1 (en)	2011-07-28
MXPA02006328A (es)	2002-12-13
EA200200595A1 (ru)	2002-12-26
DE60038698D1 (de)	2008-06-05
SI1242055T1 (sl)	2008-08-31
WO2001047500A1 (fr)	2001-07-05
BG106865A (bg)	2003-03-31
US9028870B2 (en)	2015-05-12
BR0016708A (pt)	2002-10-08
EP1242055B1 (fr)	2008-04-23
CZ20022046A3 (cs)	2002-11-13
CR6656A (es)	2004-04-29
AR027091A1 (es)	2003-03-12
TR200201646T2 (tr)	2002-11-21
EP1967185A1 (fr)	2008-09-10
PL357535A1 (en)	2004-07-26
NO20022970L (no)	2002-06-20
CA2395333C (fr)	2009-01-13
SK8572002A3 (en)	2002-12-03
US20020015731A1 (en)	2002-02-07
IS6340A (is)	2002-04-12
KR100523127B1 (ko)	2005-10-20
GT200000222A (es)	2002-06-14
HUP0301242A3 (en)	2006-07-28
ES2302705T3 (es)	2008-08-01
CA2395333A1 (fr)	2001-07-05
JP2003518489A (ja)	2003-06-10
GEP20043334B (en)	2004-03-10
NZ518281A (en)	2005-01-28
DE60038698T2 (de)	2009-05-07
AU783685B2 (en)	2005-11-24
HUP0301242A2 (hu)	2004-05-28
PE20010985A1 (es)	2001-09-28