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ZA200106289B - Crystal modification C of 8-cyano-1-cyclopropyl-7-(IS,6S-2,8-diazabicyclo-[4.3.0]nonan-8-YL)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic. - Google Patents

Crystal modification C of 8-cyano-1-cyclopropyl-7-(IS,6S-2,8-diazabicyclo-[4.3.0]nonan-8-YL)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic. Download PDF

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Publication number
ZA200106289B
ZA200106289B ZA200106289A ZA200106289A ZA200106289B ZA 200106289 B ZA200106289 B ZA 200106289B ZA 200106289 A ZA200106289 A ZA 200106289A ZA 200106289 A ZA200106289 A ZA 200106289A ZA 200106289 B ZA200106289 B ZA 200106289B
Authority
ZA
South Africa
Prior art keywords
ccdc
modification
diazabicyclo
cyclopropyl
dihydro
Prior art date
Application number
ZA200106289A
Other languages
English (en)
Inventor
Hubert Rast
Thomas Himmler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA200106289B publication Critical patent/ZA200106289B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA200106289A 1999-02-26 2001-07-31 Crystal modification C of 8-cyano-1-cyclopropyl-7-(IS,6S-2,8-diazabicyclo-[4.3.0]nonan-8-YL)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic. ZA200106289B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19908449A DE19908449A1 (de) 1999-02-26 1999-02-26 Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure

Publications (1)

Publication Number Publication Date
ZA200106289B true ZA200106289B (en) 2002-07-31

Family

ID=7899027

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200106289A ZA200106289B (en) 1999-02-26 2001-07-31 Crystal modification C of 8-cyano-1-cyclopropyl-7-(IS,6S-2,8-diazabicyclo-[4.3.0]nonan-8-YL)-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic.

Country Status (26)

Country Link
US (1) US6649762B1 (sk)
EP (1) EP1155018B1 (sk)
JP (1) JP2002538158A (sk)
KR (1) KR100756471B1 (sk)
CN (1) CN1191253C (sk)
AT (1) ATE226952T1 (sk)
AU (1) AU763003B2 (sk)
BR (1) BR0008493A (sk)
CA (1) CA2362801A1 (sk)
CZ (1) CZ299700B6 (sk)
DE (2) DE19908449A1 (sk)
DK (1) DK1155018T3 (sk)
ES (1) ES2181644T3 (sk)
HK (1) HK1044948B (sk)
HU (1) HUP0200006A3 (sk)
IL (2) IL144702A0 (sk)
NO (1) NO320191B1 (sk)
NZ (1) NZ513750A (sk)
PL (1) PL349368A1 (sk)
PT (1) PT1155018E (sk)
RU (1) RU2248356C2 (sk)
SK (1) SK285562B6 (sk)
TR (1) TR200102434T2 (sk)
UA (1) UA70356C2 (sk)
WO (1) WO2000052009A1 (sk)
ZA (1) ZA200106289B (sk)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure
DE102004015981A1 (de) * 2004-04-01 2005-10-20 Bayer Healthcare Ag Neue kirstalline Form von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE102006049520A1 (de) * 2006-10-20 2008-04-24 Bayer Healthcare Ag Verfahren zur Herstellung von Pradofloxacin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2676521B2 (ja) 1988-03-22 1997-11-17 北陸製薬株式会社 キノロンカルボン酸化合物ｉ型結晶の製造法
JPH10509169A (ja) * 1994-11-18 1998-09-08 ファルマシア・アンド・アップジョン・カンパニー 新規な物理学的に安定な固体形のフルオロキノロン
DE19546249A1 (de) * 1995-12-12 1997-06-19 Bayer Ag Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen
EP0882049B1 (de) * 1996-02-23 2002-11-20 Bayer Ag Gegebenenfalls substituierte 8-cyan-1-cyclopropyl-7-(2,8-diazabicyclo- 4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre derivate
DE19633805A1 (de) * 1996-02-23 1997-08-28 Bayer Ag Gegenenenfalls substituierte 8-Cyan-l-cyclopropyl-7-(2,8-diazabicyclo-[4.3.0]-nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren und ihre Derivate
DE19854356A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation A von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo-/4.3.0/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19854355A1 (de) 1998-11-25 2000-05-31 Bayer Ag Kristallmodifikation B von 8-Cyan-1-cyclopropyl-7-(1S, 6S-2,8-diazabicyclo-/4.3.O/nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure
DE19908448A1 (de) 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation D von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo[4.3.0)nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino incarbonsäure
DE19908449A1 (de) * 1999-02-26 2000-08-31 Bayer Ag Kristallmodifikation C von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicylo-[4.3.0]nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chino/incarbonsäure

Also Published As

Publication number Publication date
ES2181644T3 (es) 2003-03-01
HK1044948B (zh) 2005-10-14
TR200102434T2 (tr) 2002-03-21
HK1044948A1 (en) 2002-11-08
UA70356C2 (uk) 2004-10-15
CA2362801A1 (en) 2000-09-08
RU2248356C2 (ru) 2005-03-20
KR100756471B1 (ko) 2007-09-07
HUP0200006A2 (en) 2002-06-29
CZ299700B6 (cs) 2008-10-22
EP1155018B1 (de) 2002-10-30
AU3154300A (en) 2000-09-21
BR0008493A (pt) 2002-02-05
PL349368A1 (en) 2002-07-15
IL144702A0 (en) 2002-06-30
ATE226952T1 (de) 2002-11-15
NZ513750A (en) 2001-09-28
CZ20013064A3 (cs) 2002-01-16
DE50000700D1 (de) 2002-12-05
NO20014061D0 (no) 2001-08-21
CN1342160A (zh) 2002-03-27
NO320191B1 (no) 2005-11-07
AU763003B2 (en) 2003-07-10
JP2002538158A (ja) 2002-11-12
PT1155018E (pt) 2003-02-28
KR20010089630A (ko) 2001-10-06
DK1155018T3 (da) 2003-02-17
DE19908449A1 (de) 2000-08-31
US6649762B1 (en) 2003-11-18
NO20014061L (no) 2001-08-21
CN1191253C (zh) 2005-03-02
SK11952001A3 (sk) 2001-12-03
EP1155018A1 (de) 2001-11-21
HUP0200006A3 (en) 2002-08-28
SK285562B6 (sk) 2007-03-01
IL144702A (en) 2006-07-05
WO2000052009A1 (de) 2000-09-08

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