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WO2000018362A1 - Stimulant de la pousse de cheveux - Google Patents

Stimulant de la pousse de cheveux Download PDF

Info

Publication number
WO2000018362A1
WO2000018362A1 PCT/ZA1999/000102 ZA9900102W WO0018362A1 WO 2000018362 A1 WO2000018362 A1 WO 2000018362A1 ZA 9900102 W ZA9900102 W ZA 9900102W WO 0018362 A1 WO0018362 A1 WO 0018362A1
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
gestagen
composition
hair
progesterone
Prior art date
Application number
PCT/ZA1999/000102
Other languages
English (en)
Inventor
Gavin Deon Petersen
Original Assignee
Petersen, Sharleen, Caron
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Petersen, Sharleen, Caron filed Critical Petersen, Sharleen, Caron
Priority to AU64349/99A priority Critical patent/AU6434999A/en
Publication of WO2000018362A1 publication Critical patent/WO2000018362A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners

Definitions

  • This invention relates to a pharmaceutical composition for the therapeutic and prophylactic treatment of hair loss and extends to a composition for use in the manufacture of such a pharmaceutical composition and to a method of treating hair loss.
  • Baldness or the loss of hair is a condition which affects many men, particularly in later life. This is known as male pattern baldness. Hair loss can also result from any one of a number of disease treatment regimes, the most common being chemotherapy which is used to treat certain forms of cancer. Whatever the cause, hair loss often causes psychological problems.
  • compositions which do, at least partially, stimulate hair growth tend to have, as active ingredients, alpha-reductase inhibitors and one such composition utilises a vitamin A complex.
  • Gestagens a group of female sex hormones produced during the ovarian cycle and during pregnancy, have been used as a contraceptive where they act by simulating pregnancy and preventing ovulation.
  • the primary gestagens are oestrogens and progesterones. When so used the gestagens are administered orally in tablet form or they are injected intramuscularly to avoid having to ingest an oral dose most days of the ovarian cycle.
  • Gestagens are also used in certain circumstances to combat hurstitutness or excessive body hair. In such cases it is also ingested orally. To the best of the applicant's knowledge, there are no cases of gestagens being used to promote or stimulate hair growth.
  • a pharmaceutical composition for use in treating hair loss comprising a gestagen or a pharmaceutically acceptable salt or ester thereof together with such adjuvants and additives as are necessary to render the composition topically applicable to an area where stimulation of hair growth is desired.
  • the gestagen is also provided for the gestagen to be an oestrogen, preferably a synthetic oestrogen.
  • the gestagen is a progesterone, preferably a synthetic progesterone, further preferably medroxyprogesterone, and particularly medroxyprogesterone acetate.
  • adjuvants and additives are commonly found in lotions, particularly hair lotions, shampoos, hair conditioners and the like.
  • composition to be usable for therapeutic and/or prophylactic treatment of hair loss.
  • said pharmaceutical composition to an area of said mammal where stimulation of hair growth is desired.
  • the gestagen is also provided for the gestagen to be an oestrogen, preferably a synthetic oestrogen.
  • the gestagen is a progesterone, preferably a synthetic progesterone, further preferably medroxyprogesterone, and particularly medroxyprogesterone acetate.
  • adjuvants and additives are commonly found in lotions, particularly hair lotions, shampoos, hair conditioners and the like.
  • composition to be usable for therapeutic and/or prophylactic treatment of hair loss.
  • a method of treating hair loss in a mammal comprising topically administering, to said mammal, a composition comprising a gestagen or a pharmaceutically acceptable salt or ester thereof together with such adjuvants and additives as are necessary to render the composition topically applicable.
  • the gestagen is also provided for the gestagen to be an oestrogen, preferably a synthetic oestrogen.
  • the gestagen is a progesterone, preferably a synthetic progesterone, further preferably medroxyprogesterone, and particularly medroxyprogesterone acetate.
  • adjuvants and additives are commonly found in lotions, particularly hair lotions, shampoos, hair conditioners and the like.
  • composition to be usable for therapeutic and/or prophylactic treatment of hair loss.
  • synthetically manufactured medroxyprogesterone acetate is used as the active ingredient or gestagen.
  • the shampoo is used in the normal way to wash one's hair.
  • regular twice weekly washing resulted in an increase in hair density and an increase in the rate of hair growth.
  • synthetically manufactured medroxyprogesterone acetate is mixed with polyethylene glycol and water.
  • concentration of medroxyprogesterone acetate is between 0.1% and 5% by volume.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une composition permettant de stimuler la pousse des cheveux. La composition comprend comme ingrédient actif, un progestatif, de préférence de l'acétate de médroxyprogestérone synthétique. L'ingrédient actif est mélangé avec des adjuvants et des additifs tels que ceux nécessairement utilisés pour qu'il soit possible de l'appliquer de manière topique sous forme de lotion ou de shampooing. L'invention englobe également un procédé de traitement de la chute des cheveux.
PCT/ZA1999/000102 1998-09-28 1999-09-28 Stimulant de la pousse de cheveux WO2000018362A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU64349/99A AU6434999A (en) 1998-09-28 1999-09-28 Hair growth stimulant

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA987846 1998-09-28
ZA98/7846 1998-09-28

Publications (1)

Publication Number Publication Date
WO2000018362A1 true WO2000018362A1 (fr) 2000-04-06

Family

ID=25587241

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ZA1999/000102 WO2000018362A1 (fr) 1998-09-28 1999-09-28 Stimulant de la pousse de cheveux

Country Status (2)

Country Link
AU (1) AU6434999A (fr)
WO (1) WO2000018362A1 (fr)

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE727044A (fr) * 1968-01-17 1969-07-17
DE2757024A1 (de) * 1977-12-21 1979-06-28 Juergen Prof Dr Med Tamm Kosmetisches haar- und hautpflegemittel
DE2840144A1 (de) * 1978-09-15 1980-03-27 Goedecke Ag Topisch applizierbares arzneimittel mit antiandrogener wirkung
US4272508A (en) * 1979-03-30 1981-06-09 Jurgen Tamm Cosmetics for treatment of hair and skin
EP0123528A1 (fr) * 1983-04-19 1984-10-31 Christopher Harry Dr. Mortimer Composition pharmaceutique pour le traitement de la chute des cheveux
GB2144991A (en) * 1983-08-11 1985-03-20 Yoshiaki Oshima Hair growth promotor
EP0163489A1 (fr) * 1984-05-22 1985-12-04 Christopher Harry Dr. Mortimer Traitement de la perte des cheveux chez les femmes
JPS61183209A (ja) * 1985-02-09 1986-08-15 Lion Corp 養毛料
DE3535509A1 (de) * 1985-10-02 1987-04-09 Schering Ag Pharmazeutische praeparate
WO1996001099A1 (fr) * 1994-07-06 1996-01-18 Sinvent As Composition pour le traitement de la calvitie masculine
JPH0873328A (ja) * 1994-09-05 1996-03-19 Hideyo Uji 育毛剤組成物
JPH0873327A (ja) * 1994-09-03 1996-03-19 Hideyo Uji 育毛剤組成物
DE19534209A1 (de) * 1995-09-15 1997-03-20 Jenapharm Gmbh Hormonales Mittel zur Behandlung der Haut

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE727044A (fr) * 1968-01-17 1969-07-17
DE2757024A1 (de) * 1977-12-21 1979-06-28 Juergen Prof Dr Med Tamm Kosmetisches haar- und hautpflegemittel
DE2840144A1 (de) * 1978-09-15 1980-03-27 Goedecke Ag Topisch applizierbares arzneimittel mit antiandrogener wirkung
US4272508A (en) * 1979-03-30 1981-06-09 Jurgen Tamm Cosmetics for treatment of hair and skin
EP0123528A1 (fr) * 1983-04-19 1984-10-31 Christopher Harry Dr. Mortimer Composition pharmaceutique pour le traitement de la chute des cheveux
GB2144991A (en) * 1983-08-11 1985-03-20 Yoshiaki Oshima Hair growth promotor
EP0163489A1 (fr) * 1984-05-22 1985-12-04 Christopher Harry Dr. Mortimer Traitement de la perte des cheveux chez les femmes
JPS61183209A (ja) * 1985-02-09 1986-08-15 Lion Corp 養毛料
DE3535509A1 (de) * 1985-10-02 1987-04-09 Schering Ag Pharmazeutische praeparate
WO1996001099A1 (fr) * 1994-07-06 1996-01-18 Sinvent As Composition pour le traitement de la calvitie masculine
JPH0873327A (ja) * 1994-09-03 1996-03-19 Hideyo Uji 育毛剤組成物
JPH0873328A (ja) * 1994-09-05 1996-03-19 Hideyo Uji 育毛剤組成物
DE19534209A1 (de) * 1995-09-15 1997-03-20 Jenapharm Gmbh Hormonales Mittel zur Behandlung der Haut

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 198639, Derwent World Patents Index; Class D21, AN 1986-255369, XP002132195 *
DATABASE WPI Section Ch Week 199621, Derwent World Patents Index; Class B01, AN 1996-205417, XP002132196 *
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 07 31 July 1996 (1996-07-31) *

Also Published As

Publication number Publication date
AU6434999A (en) 2000-04-17

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