UY25472A1 - Procedimiento para la preparacion de fenoxifenilsulfonilo - Google Patents
Procedimiento para la preparacion de fenoxifenilsulfoniloInfo
- Publication number
- UY25472A1 UY25472A1 UY25472A UY25472A UY25472A1 UY 25472 A1 UY25472 A1 UY 25472A1 UY 25472 A UY25472 A UY 25472A UY 25472 A UY25472 A UY 25472A UY 25472 A1 UY25472 A1 UY 25472A1
- Authority
- UY
- Uruguay
- Prior art keywords
- procedure
- preparation
- compounds
- present
- phenoxifenylsulfonil
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- RFPOAIKHXKNFPZ-UHFFFAOYSA-N (4-fluorophenyl) 4-(4-fluorophenoxy)benzenesulfonate Chemical compound C1=CC(F)=CC=C1OC1=CC=C(S(=O)(=O)OC=2C=CC(F)=CC=2)C=C1 RFPOAIKHXKNFPZ-UHFFFAOYSA-N 0.000 abstract 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- -1 PHENOXYPHENYLSULFONYL HALIDES Chemical class 0.000 abstract 1
- 208000007474 aortic aneurysm Diseases 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 230000000414 obstructive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C301/00—Esters of sulfurous acid
- C07C301/02—Esters of sulfurous acid having sulfite groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/26—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
- C07C303/28—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reaction of hydroxy compounds with sulfonic acids or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/41—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton
- C07C309/42—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/75—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
UN PROCEDIMIENTO PARA PREPARAR HALUROS DE FENOXIFENILSULFONILO, QUE SON INTERMEDIOS UTILES PARA LA PREPARACION DE INHIBIDORES DE LAS METALOPROTEINASAS DE LA MATRIZ. Son de utilidad para artritis, enfermedad inflamatoria del intedstino, enfermedad obstructiva crónica, asma, Alzheimer, cáncer, osteoporosis, aneurisma aortico, diabetes, etc. La presente invención se refiere a compuestos de fórmula (IIa) en la que R es H, Li, Naa, K, Mg, etc.El esquema (I) muestra la una de las preparaciones de los compuestos de la presente invención. Éster 4-fluorofenílico del ácido 4-(4-fluorofenoxi)bencenosulfónico
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8139398P | 1998-04-10 | 1998-04-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY25472A1 true UY25472A1 (es) | 1999-11-17 |
Family
ID=22163859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY25472A UY25472A1 (es) | 1998-04-10 | 1999-04-12 | Procedimiento para la preparacion de fenoxifenilsulfonilo |
Country Status (42)
| Country | Link |
|---|---|
| US (2) | US6118016A (es) |
| EP (1) | EP0949246B1 (es) |
| JP (1) | JP3694419B2 (es) |
| KR (1) | KR100329901B1 (es) |
| CN (1) | CN1238329A (es) |
| AP (1) | AP1155A (es) |
| AR (1) | AR016205A1 (es) |
| AT (1) | ATE233729T1 (es) |
| AU (1) | AU758297B2 (es) |
| BG (1) | BG103321A (es) |
| BR (1) | BR9902041A (es) |
| CA (1) | CA2268679C (es) |
| CO (1) | CO4810300A1 (es) |
| DE (1) | DE69905633T2 (es) |
| DK (1) | DK0949246T3 (es) |
| DZ (1) | DZ2755A1 (es) |
| EA (1) | EA001756B1 (es) |
| ES (1) | ES2192021T3 (es) |
| GT (1) | GT199900044A (es) |
| HR (1) | HRP990107B1 (es) |
| HU (1) | HU221635B1 (es) |
| ID (1) | ID23645A (es) |
| IL (1) | IL129330A (es) |
| IN (1) | IN191233B (es) |
| IS (1) | IS5020A (es) |
| MA (1) | MA24834A1 (es) |
| NO (1) | NO991679L (es) |
| NZ (1) | NZ335106A (es) |
| OA (1) | OA11032A (es) |
| PA (1) | PA8469801A1 (es) |
| PE (1) | PE20000416A1 (es) |
| PL (1) | PL332452A1 (es) |
| SG (1) | SG75169A1 (es) |
| SI (1) | SI0949246T1 (es) |
| SK (1) | SK44999A3 (es) |
| TN (1) | TNSN99051A1 (es) |
| TR (1) | TR199900757A3 (es) |
| TW (1) | TW539664B (es) |
| UA (1) | UA59373C2 (es) |
| UY (1) | UY25472A1 (es) |
| YU (1) | YU18299A (es) |
| ZA (1) | ZA992628B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6458822B2 (en) | 2000-03-13 | 2002-10-01 | Pfizer Inc. | 2-oxo-imidazolidine-4-carboxylic acid hydroxamide compounds that inhibit matrix metalloproteinases |
| EP2428509A1 (en) * | 2002-06-12 | 2012-03-14 | Symphony Evolution, Inc. | Human adam-10 inhibitors |
| ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| JP5830534B2 (ja) | 2010-07-09 | 2015-12-09 | ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ | 化合物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE844004C (de) * | 1944-08-06 | 1952-07-14 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von Sulfonsaeureestern |
| US4032506A (en) * | 1973-12-28 | 1977-06-28 | General Electric Company | Flame retardant polycarbonate composition |
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| GB9000725D0 (en) * | 1990-01-12 | 1990-03-14 | Pfizer Ltd | Therapeutic agents |
| US5340489A (en) * | 1992-06-05 | 1994-08-23 | The Dow Chemical Company | Aryl arenesulfonates and a method of lubrication using the aryl arenesulfonates |
| US5863949A (en) * | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
| EP0922030A1 (en) * | 1996-08-23 | 1999-06-16 | Pfizer Inc. | Arylsulfonylamino hydroxamic acid derivatives |
| ATE248812T1 (de) * | 1997-02-03 | 2003-09-15 | Pfizer Prod Inc | Arylsulfonylhydroxamsäurederivate |
| AU7294098A (en) * | 1997-05-09 | 1998-11-27 | Agouron Pharmaceuticals, Inc. | Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses |
| JP3448275B2 (ja) * | 1997-08-08 | 2003-09-22 | ファイザー・プロダクツ・インク | アリールオキシアリールスルホニルアミノヒドロキサム酸誘導体 |
| EP0895988B1 (en) * | 1997-08-08 | 2002-05-22 | Pfizer Products Inc. | Arylsulfonylamino hydroxamic acid derivatives |
| PA8469401A1 (es) * | 1998-04-10 | 2000-05-24 | Pfizer Prod Inc | Derivados biciclicos del acido hidroxamico |
-
1999
- 1999-03-24 GT GT199900044A patent/GT199900044A/es unknown
- 1999-03-26 PA PA19998469801A patent/PA8469801A1/es unknown
- 1999-04-01 OA OA9900075A patent/OA11032A/en unknown
- 1999-04-05 IL IL12933099A patent/IL129330A/xx not_active IP Right Cessation
- 1999-04-06 IN IN511DE1999 patent/IN191233B/en unknown
- 1999-04-06 SK SK449-99A patent/SK44999A3/sk unknown
- 1999-04-06 PE PE1999000276A patent/PE20000416A1/es not_active Application Discontinuation
- 1999-04-06 TW TW088105444A patent/TW539664B/zh not_active IP Right Cessation
- 1999-04-06 IS IS5020A patent/IS5020A/is unknown
- 1999-04-07 US US09/287,930 patent/US6118016A/en not_active Expired - Fee Related
- 1999-04-07 MA MA25531A patent/MA24834A1/fr unknown
- 1999-04-07 KR KR1019990011940A patent/KR100329901B1/ko not_active IP Right Cessation
- 1999-04-07 TN TNTNSN99051A patent/TNSN99051A1/fr unknown
- 1999-04-07 DZ DZ990056A patent/DZ2755A1/xx active
- 1999-04-07 JP JP10000199A patent/JP3694419B2/ja not_active Expired - Fee Related
- 1999-04-08 AP APAP/P/1999/001509A patent/AP1155A/en active
- 1999-04-08 YU YU18299A patent/YU18299A/sh unknown
- 1999-04-08 UA UA99042000A patent/UA59373C2/uk unknown
- 1999-04-08 EP EP99302744A patent/EP0949246B1/en not_active Expired - Lifetime
- 1999-04-08 ES ES99302744T patent/ES2192021T3/es not_active Expired - Lifetime
- 1999-04-08 AR ARP990101602A patent/AR016205A1/es unknown
- 1999-04-08 SG SG1999001821A patent/SG75169A1/en unknown
- 1999-04-08 AT AT99302744T patent/ATE233729T1/de not_active IP Right Cessation
- 1999-04-08 CA CA002268679A patent/CA2268679C/en not_active Expired - Fee Related
- 1999-04-08 DK DK99302744T patent/DK0949246T3/da active
- 1999-04-08 TR TR1999/00757A patent/TR199900757A3/tr unknown
- 1999-04-08 DE DE69905633T patent/DE69905633T2/de not_active Expired - Fee Related
- 1999-04-08 ID IDP990311D patent/ID23645A/id unknown
- 1999-04-08 SI SI9930219T patent/SI0949246T1/xx unknown
- 1999-04-09 AU AU23692/99A patent/AU758297B2/en not_active Ceased
- 1999-04-09 BG BG103321A patent/BG103321A/xx unknown
- 1999-04-09 HR HR990107A patent/HRP990107B1/xx not_active IP Right Cessation
- 1999-04-09 NO NO991679A patent/NO991679L/no not_active Application Discontinuation
- 1999-04-09 PL PL99332452A patent/PL332452A1/xx unknown
- 1999-04-09 ZA ZA9902628A patent/ZA992628B/xx unknown
- 1999-04-09 HU HU9901042A patent/HU221635B1/hu not_active IP Right Cessation
- 1999-04-09 CN CN99104929A patent/CN1238329A/zh active Pending
- 1999-04-09 NZ NZ335106A patent/NZ335106A/xx unknown
- 1999-04-09 EA EA199900282A patent/EA001756B1/ru not_active IP Right Cessation
- 1999-04-12 UY UY25472A patent/UY25472A1/es unknown
- 1999-04-12 CO CO99021410A patent/CO4810300A1/es unknown
- 1999-04-12 BR BR9902041-6A patent/BR9902041A/pt not_active IP Right Cessation
-
2000
- 2000-12-19 US US09/740,398 patent/US20010011143A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR0162081B1 (ko) | 4-하이드록시테트라하이드로피란-2-온 및 상응하는 디하이드록시카복실산유도체, 염 및 에스테르, 이의 제조방법 및 이의 전구체 | |
| US4153803A (en) | Cholesterol-lowering phenoxyalkanoic acid esters | |
| DK1088819T3 (da) | 6-azauracilderivater som thyroidreceptorligander | |
| BR0000968A (pt) | ácidos oxâmicos contendo ciano e seus derivados como ligantes de receptores da tiróide | |
| EA200400762A1 (ru) | Новые соединения, их использование в медицине, способ их изготовления и содержащие их фармацевтические композиции | |
| GT200000190A (es) | Procedimiento para la obtencion de 1,2,3,4-tetrahidroquinolinas-4-carboxiamino-2-sustituidas. | |
| JP2022537605A (ja) | Ｃｒｂｎタンパク質モジュレーターとしての二環式化合物 | |
| HU183206B (en) | Process for preparing substituted oxirane-carboxylic acids | |
| Sheridan et al. | Synthesis and antispasmodic activity of analogues of natural pterosins | |
| UY25472A1 (es) | Procedimiento para la preparacion de fenoxifenilsulfonilo | |
| WO2001042186A1 (fr) | Compose a chaine laterale hydroxycarbonyl-halogenoalkyle | |
| JPH07502505A (ja) | 人好中球エラスターゼの阻害剤としてのフエニレンジアルカノエート類の芳香族エステル類 | |
| PT86874B (pt) | Processo para a preparacao de derivados da cromona e de composicoes farmaceuticas que os contem | |
| JPH0495025A (ja) | アルドースリダクターゼ阻害剤 | |
| JP2021509909A (ja) | Ｇｐｒ４０アゴニストとしての３−フェニル−４−ヘキシン酸誘導体 | |
| PT94866A (pt) | Processo para a preparacao de derivados de cumarina | |
| WO2013159724A1 (zh) | 4-((取代苯基)二氟甲基)苯氧基羧酸衍生物及其制备方法和用途 | |
| US4832875A (en) | Vitamin D3 derivative | |
| EP2216322A1 (en) | Retinoid prodrug compound | |
| Fryatt et al. | The synthesis of multiply 13C‐labelled plant and mammalian lignans as internal standards for LC‐MS and GC‐MS analysis | |
| US20120029223A1 (en) | Method for production of substituted alkyl malonic esters and derivatives thereof | |
| US7084133B2 (en) | Dicarba-closo-dodecaborane derivatives | |
| JPH06206842A (ja) | ４−アルコキシ−２，６−ジ−ｔ−ブチルフェノール誘導体 | |
| AU661722B2 (en) | Substituted hydroquinone derivatives | |
| US6436973B1 (en) | LTA4 hydrolase inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DESI | Application deemed to be withdrawn |
Effective date: 20071105 |