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US9014517B2 - Fiber unit - Google Patents

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Publication number
US9014517B2
US9014517B2 US14/099,239 US201314099239A US9014517B2 US 9014517 B2 US9014517 B2 US 9014517B2 US 201314099239 A US201314099239 A US 201314099239A US 9014517 B2 US9014517 B2 US 9014517B2
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Prior art keywords
unit
fiber
distal end
fibers
covering
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US20140177266A1 (en
Inventor
Masahiro Katakura
Takeshi Suga
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Olympus Corp
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Olympus Medical Systems Corp
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Priority to US14/099,239 priority Critical patent/US9014517B2/en
Assigned to OLYMPUS MEDICAL SYSTEMS CORP. reassignment OLYMPUS MEDICAL SYSTEMS CORP. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: SUGA, TAKESHI, KATAKURA, MASAHIRO
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Assigned to OLYMPUS CORPORATION reassignment OLYMPUS CORPORATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: OLYMPUS MEDICAL SYSTEMS CORP.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00165—Optical arrangements with light-conductive means, e.g. fibre optics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02—Optical fibres with cladding with or without a coating
    • G02B6/02042—Multicore optical fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00

Definitions

  • the present invention relates to a fiber unit used in a measurement probe that emits irradiation light to a sample and receives light from the sample.
  • an optical measurement system which emits illumination light onto a sample such as a biological tissue and estimates characteristics of the sample on the basis of a measurement value of detected light reflected or scattered by the sample.
  • Such an optical measurement system is constituted using: a light source emitting illumination light to a sample; an optical measurement apparatus having a detection unit detecting detected light from the sample; and a measurement probe, which is attachable to and detachable from the optical measurement apparatus, emits irradiation light to the sample, and receives light from the sample.
  • the measurement probe has a fiber unit including: an illumination fiber, one end of which is connected to a light source and the other end of which emits illumination light to a biological tissue; and a light receiving fiber, one end of which is connected to the detection unit and the other end of which receives light emitted from the biological tissue by emission from the emission fiber.
  • LEBS low-coherence enhanced backscattering
  • a diameter of the measurement probe is demanded in order to reduce burden placed on a patient upon insertion of the measurement probe inside the patient's body. For this demand, a diameter of each fiber of a fiber unit is required to be also decreased.
  • Japanese Laid-open Patent Publication No. 5-341158 discloses a technique in which a receiving end portion of each fiber is bent to narrow a distance between the fibers, thereby decreasing the diameter, for example.
  • a fiber unit has one or a plurality of illumination fibers and a plurality of detection fibers and is provided in a measurement probe that performs optical measurement by inputting and outputting light from a distal end thereof.
  • Each of the illumination fibers and the detection fibers includes: a soft portion that is bendable; a distal end hard portion provided at an end thereof and having a greater hardness than the soft portion; and a pitch conversion portion that connects the soft portion and the distal end hard portion and changes a distance between adjacent fibers at the distal end hard portion with respect to a distance between the adjacent fibers at the soft portion, by bending and extending.
  • FIG. 1 is a block diagram schematically illustrating a configuration of an optical measurement system according to an embodiment of the present invention
  • FIG. 2 is a diagram schematically illustrating a cross section of a distal end portion of a measurement probe including an optical element of the optical measurement system according to the embodiment of the present invention, cut along a longitudinal direction;
  • FIG. 3 is a plan view schematically illustrating a measurement probe in a direction of arrow A of FIG. 2 ;
  • FIG. 4 is a diagram illustrating the optical measurement system according to the embodiment of the present invention upon use in an endoscopic system
  • FIG. 5 is a schematic diagram illustrating a configuration of an emission fiber of the optical measurement system according to the embodiment of the present invention.
  • FIG. 6 is a plan view schematically illustrating the emission fiber in a direction of arrow B of FIG. 5 ;
  • FIG. 7 is a cross sectional view schematically illustrating a configuration of the emission fiber of the optical measurement system according to the embodiment of the present invention.
  • FIG. 8 is a diagram illustrating distances between fibers of a fiber unit according to examples of the present invention.
  • FIG. 1 is a block diagram schematically illustrating a configuration of an optical measurement system according to an embodiment of the present invention.
  • An optical measurement system 1 illustrated in FIG. 1 includes: an optical measurement apparatus 2 that performs optical measurement with respect to an object to be measured, such as a biological tissue, which is a scatterer, and detects characteristics (properties) of the object to be measured; and a measurement probe 3 which is attachable to and detachable from the optical measurement apparatus 2 and inserted into a subject.
  • an optical measurement apparatus 2 that performs optical measurement with respect to an object to be measured, such as a biological tissue, which is a scatterer, and detects characteristics (properties) of the object to be measured
  • a measurement probe 3 which is attachable to and detachable from the optical measurement apparatus 2 and inserted into a subject.
  • the optical measurement apparatus 2 includes a power source 21 , a light source unit 22 , a connection unit 23 , a light receiving unit 24 , an input unit 25 , an output unit 26 , a recording unit 27 , and a controller 28 .
  • the power source 21 supplies electric power to each component of the optical measurement apparatus 2 .
  • the light source unit 22 is realized using an incoherent light source such as a white LED (light emitting diode), a xenon lamp, a tungsten lamp, or a halogen lamp, and, as necessary, one or more lenses, e.g., a condenser lens, a collimation lens, or the like.
  • the light source unit 22 outputs, to the measurement probe 3 , incoherent light having at least one spectrum component to be irradiated onto the object to be measured via the connection unit 23 .
  • the connection unit 23 detachably connects a connector unit 31 of the measurement probe 3 to the optical measurement apparatus 2 .
  • the connection unit 23 outputs the light emitted by the light source unit 22 to the measurement probe 3 , and outputs, to the light receiving unit 24 , returned light of illumination light, which is emitted by the measurement probe 3 and reflected and/or scattered by the object to be measured.
  • the connection unit 23 outputs, to the controller 28 , information about whether the measurement probe 3 is connected or not.
  • the light receiving unit 24 receives and measures the returned light of the illumination light, which is the illumination light emitted from the measurement probe 3 and reflected and/or scattered by the object to be measured.
  • the light receiving unit 24 is realized using a plurality of spectrometric devices or light receiving sensors. More specifically, in the light receiving unit 24 , the spectrometric devices are provided according to the number of light receiving fibers of the measurement probe 3 explained later.
  • the light receiving unit 24 measures spectrum components and intensity distribution of the scattered light entering from the measurement probe 3 , and performs measurement for each wavelength.
  • the light receiving unit 24 outputs results of the measurement to the controller 28 .
  • the input unit 25 is realized using a push-type switch, a touch panel, or the like, receives input of an instruction signal instructing activation of the optical measurement apparatus 2 or an instruction signal instructing any of other various kinds of operations, and outputs the instruction signal to the controller 28 .
  • the output unit 26 is realized using a display of liquid crystal or organic EL (electroluminescence) and a speaker or the like, and outputs information about various kinds of processing in the optical measurement apparatus 2 . Further, under control by the controller 28 , the output unit 26 displays on the display numerical values such as intensities of light received by the light receiving unit 24 (characteristics values calculated by an calculation unit 28 a explained later).
  • the recording unit 27 is realized using a volatile memory and a nonvolatile memory, and records various kinds of programs for operating the optical measurement apparatus 2 , and various kinds of data and various kinds of parameters used for optical measurement processing.
  • the recording unit 27 temporarily records information during processing of the optical measurement apparatus 2 .
  • the recording unit 27 records results of measurement by the optical measurement apparatus 2 in association with a subject to be measured.
  • the recording unit 27 may be configured using a memory card or the like, which is attached from the outside of the optical measurement apparatus 2 .
  • the controller 28 is configured using a CPU (central processing unit) or the like.
  • the controller 28 controls processing operations of each unit of the optical measurement apparatus 2 .
  • the controller 28 controls operations of the optical measurement apparatus 2 by, e.g., transferring instruction information and data corresponding to each unit of the optical measurement apparatus 2 .
  • the controller 28 records the results of the measurement by the light receiving unit 24 in the recording unit 27 .
  • the controller 28 has a calculation unit 28 a.
  • the calculation unit 28 a performs, on the basis of the results of the measurement by the light receiving unit 24 , a plurality of operation processes, and calculates characteristic values related to the characteristics of the object to be measured.
  • a type of these characteristics values is set, for example, according to an instruction signal received by the input unit 25 .
  • the measurement probe 3 is realized by arranging a plurality of optical fibers inside. More specifically, the measurement probe 3 is realized using an illumination fiber that emits illumination light onto the object to be measured and a plurality of light receiving fibers into which returned light of the illumination light reflected and/or scattered by the object to be measured enters at different angles.
  • the measurement probe 3 includes: a connector unit 31 detachably connected to the connection unit 23 of the optical measurement apparatus 2 ; a flexible unit 32 having flexibility; and a distal end portion 33 which irradiates the illumination light supplied by the light source unit 22 and receives the returned light from the object to be measured.
  • FIG. 2 is a diagram schematically illustrating a cross section of the distal end portion 33 of the measurement probe 3 cut along a longitudinal direction.
  • FIG. 3 is a plan view schematically illustrating the measurement probe 3 in a direction of arrow A of FIG. 2 .
  • the distal end portion 33 is provided with an optical element 34 partly constituting an external surface of the measurement probe 3 .
  • the measurement probe 3 includes: a fiber unit 310 including an illumination fiber 311 that irradiates the illumination light onto the object to be measured, and a first light receiving fiber 312 , a second light receiving fiber 313 , and a third light receiving fiber 314 , into which the returned light of the illumination light reflected and/or scattered by the object to be measured enters; a covering member 315 of glass, resin, or the like, which prevents scratches on and fixes positions of the illumination fiber 311 , the first light receiving fiber 312 , the second light receiving fiber 313 , and the third light receiving fiber 314 ; a protection unit 316 of glass, brass, or the like, which protects the covering member 315 from external force; and a probe outer cover 317 made of SUS or the like, which covers an external peripheral surface of the protection unit 316 and the optical element 34 .
  • the illumination fiber 311 transmits the illumination light output from the light source unit 22 and irradiates the illumination light onto the object to be measured via the optical element 34 .
  • the number of illumination fibers 311 may be changed as necessary according to an item to be examined or the type of the object to be measured, e.g., a bloodstream or a locus.
  • the illumination fiber 311 is configured using a step-index-type single-core fiber.
  • the first light receiving fiber 312 , the second light receiving fiber 313 , and the third light receiving fiber 314 transmit the returned light of the illumination light reflected and/or scattered by the object to be measured and entering from their respective distal ends via the optical element 34 , and output it to the light receiving unit 24 of the optical measurement apparatus 2 .
  • the number of light receiving fibers may be changed as necessary according to the item to be examined or the type of the object to be measured, e.g., a bloodstream or a locus.
  • the first light receiving fiber 312 , the second light receiving fiber 313 , and the third light receiving fiber 314 are configured using step-index-type single-core fibers.
  • the optical element 34 is cylindrically shaped, and is configured using transparent glass having a predetermined refractive index.
  • the optical element 34 fixes a distance between the illumination fiber 311 and the object to be measured, and is formed to be able to emit light with a constant spatial coherent length.
  • the optical element 34 fixes each of a distance between the first light receiving fiber 312 and the object to be measured, a distance between the second light receiving fiber 313 and the object to be measured, and a distance between the third light receiving fiber 314 and the object to be measured, and is formed to be able to stably receive the returned light at a predetermined scattering angle.
  • the measurement probe 3 is inserted into the subject via a treatment tool channel 111 provided in an endoscopic apparatus 110 (endoscope) of an endoscopic system 100 , and the illumination fiber 311 irradiates the illumination light onto the object to be measured, and the first light receiving fiber 312 , the second light receiving fiber 313 , and the third light receiving fiber 314 respectively receive the returned light beams of the illumination light reflected and/or scattered by the object to be measured at different scattering angles, and transmit them to the light receiving unit 24 of the optical measurement apparatus 2 . Thereafter, the calculation unit 28 a calculates characteristic values for the characteristics of the object to be measured on the basis of the results of the measurement by the light receiving unit 24 .
  • the illumination fiber 311 , the first light receiving fiber 312 , the second light receiving fiber 313 , and the third light receiving fiber 314 of the measurement probe 3 are bent so that distances between adjacent fibers at the distal end portion 33 are shortened, and are in contact with the optical element 34 .
  • FIG. 5 is a schematic diagram illustrating a configuration of the emission fiber 311 of the optical measurement system 1 according to the present embodiment.
  • FIG. 6 is a plan view schematically illustrating the emission fiber 311 in a direction of arrow B of FIG. 5 .
  • FIG. 7 is a cross sectional view schematically illustrating a configuration of the emission fiber 311 of the optical measurement system 1 according to the present embodiment.
  • the illumination fiber 311 includes a soft portion 331 which is inserted into the flexible unit 32 and which is bendable, a distal end hard portion 332 which is a light-receiving end portion and has a hardness greater than the soft portion 331 , and a pitch conversion portion 333 which connects the soft portion 331 and the end hard portion 332 and changes a distance (pitch) from another fiber adjacent thereto at the distal end hard portion 332 with respect to a distance between adjacent fibers at the soft portion 331 , by bending and extending at both ends thereof.
  • the first light receiving fiber 312 , the second light receiving fiber 313 , and the third light receiving fiber 314 also have the same configuration.
  • the pitch conversion portion 333 connects the soft portion 331 and the end hard portion 332 in such a way that a line through a central axis of the soft portion 331 does not coincide with a line though a central axis of the end hard portion 332 .
  • the pitch conversion portion 333 may be straight-lined, for example, inclined with respect to the central axis of the soft portion 331 , and extended.
  • the pitch conversion portion 333 may be arc-shaped so that the line through the central axis of the soft portion 331 does not coincide with the line though the central axis of the end hard portion 332 .
  • a line through a central axis of the soft portion 331 may coincide with a line though a central axis of the end hard portion 332 .
  • the inclination angle Deg_max for preventing fiber breakage satisfies the following conditional expression.
  • the present embodiment is described assuming that the pitch conversion portion 333 is straight-lined, and the inclination angle is an angle formed by the pitch conversion portion 333 and a central axis of the distal end hard portion 332 .
  • the illumination fiber 311 includes: a light transmission unit 350 including a core unit 311 a (core), which transmits light and is approximately bar-shaped, and an outer layer unit 311 b (clad), which covers an external periphery of the core unit 311 a and has a smaller refractive index than the core unit 311 a ; a first covering unit 351 covering a lateral surface of the outer layer unit 311 b of the soft portion 331 of the illumination fiber 311 ; and a second covering unit 352 , which is provided at the light-receiving end of the illumination fiber 311 (the distal end hard portion 332 and the pitch conversion portion 333 ) and covers the lateral surface of the outer layer unit 311 b .
  • a light transmission unit 350 including a core unit 311 a (core), which transmits light and is approximately bar-shaped, and an outer layer unit 311 b (clad), which covers an external periphery of the core unit 311 a and has a smaller refractive index than the
  • the lateral surface of the outer layer unit 311 b is covered with the first covering unit 351 and the second covering unit 352 .
  • a covering thickness D 1 of the outer layer unit 311 b of the first covering unit 351 is different from a covering thickness D 2 of the outer layer unit 311 b of the second covering unit 352 , and satisfies a relation, D 2 ⁇ D 1 .
  • the first light receiving fiber 312 , the second light receiving fiber 313 , and the third light receiving fiber 314 also have the same configuration.
  • the refractive index of the core unit 311 a is greater than the refractive index of the outer layer unit 311 b , and therefore, light is mainly transmitted by the core unit 311 a.
  • a length D A of the pitch conversion portion 333 with respect to the covering thickness D 1 for preventing fiber breakage satisfies the following conditional expression.
  • the length D A of the pitch conversion portion is a length ( ) along a longitudinal direction of the distal end hard portion 332 (the central axis of the fiber). 0.005 ⁇ D 1 /D A ⁇ 0.032 (2)
  • the covering thicknesses D 1 and D 2 for preventing fiber breakage satisfy the following conditional expression. 15 ⁇ D 1 /D 2 ⁇ 100 (3)
  • the illumination fiber 311 , the first light receiving fiber 312 , the second light receiving fiber 313 , and the third light receiving fiber 314 satisfy the following conditional expressions. 0.20 ⁇ NA ⁇ 0.25 (4) 15 ⁇ m ⁇ D_core ⁇ 45 ⁇ m (5) 0.60 ⁇ D _core/ D _clad ⁇ 0.75 (6)
  • NA denotes a numerical aperture of each of the illumination fiber 311 and the first light receiving fiber 312 to third light receiving fiber 314 .
  • D_core denotes a core diameter of the core unit 311 a of each of the illumination fiber 311 and first light receiving fiber 312 to third light receiving fiber 314 .
  • D_clad is a clad diameter of the outer layer unit 311 b of each of the illumination fiber 311 and the first light receiving fiber 312 to third light receiving fiber 314 .
  • the core diameter D_core of the core unit 311 a is within the range of 15 ⁇ m ⁇ D_core ⁇ 45 ⁇ m, a distance between centers of the core units 311 a of the fibers are reducible while an appropriate quantity of light is able to be input and output.
  • the core diameter D_core of the core unit 311 a and the clad diameter D_clad of the outer layer unit 311 b satisfy the relation of 0.60 ⁇ D_core/D_clad ⁇ 0.75, it is possible to suppress increase in a diameter of the light transmission unit 350 while preventing the light transmitted by the core unit 311 a from leaking out of the outer layer unit 311 b.
  • the inclination angle Deg_max of the pitch conversion portion 333 of the most inclined fiber satisfies 1.0 degree ⁇ Deg_max ⁇ 6.0 degrees, and therefore, fiber breakage upon manufacture is preventable.
  • the length D A of the pitch conversion portion 333 with respect to the covering thickness D 1 satisfies the relation of 0.005 ⁇ D 1 /D A ⁇ 0.032, and therefore, the covering thickness D 1 of the first covering unit 351 with respect to the length of the pitch conversion portion 333 becomes an appropriate ratio, and the inclination angle Deg_max of the pitch conversion portion 333 is able to satisfy 1.0 degree ⁇ Deg_max ⁇ 6.0 degrees.
  • the covering thicknesses D 1 and D 2 are adapted to satisfy the relation of 15 ⁇ D 1 /D 2 ⁇ 100, and therefore, it is possible to even more reliably prevent fiber breakage while the inclination angle Deg_max and the ratio D 1 /D A between the first covering unit 351 and the second covering unit 352 are being satisfied.
  • the pitch conversion portion 333 is straight-lined. If the pitch conversion portion 333 is arc-shaped, the inclination angle is an angle formed by the central axis of the distal end hard portion 332 and a line segment connecting an end portion of the pitch conversion portion 333 closer to the soft portion 331 and an end portion of the pitch conversion portion 333 closer to the distal end hard portion 332 , and the maximum angle thereof is the inclination angle Deg_max.
  • the present embodiment has been explained assuming that the first covering unit 351 and the second covering unit 352 are provided for the outer layer unit 311 b of the fiber, but as long as the above conditional expressions (1) to (6) are satisfied, a configuration thereof may be without the second covering unit 352 .
  • the present embodiment has been explained assuming that only one illumination fiber 311 is provided in the measurement probe 3 , but a configuration thereof may be provided with a plurality of illumination fibers.
  • Measurement probes having fibers satisfying the above conditional expressions were respectively made as examples 1 to 3.
  • a measurement probe having fibers satisfying the following conditions was made. Nickel plating or gold plating was used for the first covering unit 351 . Acrylic resin was used for the second covering unit 352 .
  • a measurement probe having fibers satisfying the following conditions was made. Nickel plating or gold plating was used for the first covering unit 351 . Acrylic resin was used for the second covering unit 352 .
  • a measurement probe having fibers satisfying the following conditions was made.
  • Each fiber according to the example 3 was not provided with the first covering unit 351 , and acrylic resin was used for the second covering unit 352 .
  • the measurement probes Upon manufacture of the measurement probes according to the above examples 1 to 3, when the fiber units having the fibers satisfying the above conditions (1) to (6) were assembled, the measurement probes were able to be manufactured without fiber breakage caused by contact or the like. Furthermore, when a fiber unit that is out of the ranges of the above conditional expressions was used and assembled, some of the fibers were broken due to contact or the like.
  • the fiber unit according to the present invention is useful in preventing the fiber breakage upon manufacture.

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Instruments For Viewing The Inside Of Hollow Bodies (AREA)
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US10254536B2 (en) 2015-07-20 2019-04-09 Magic Leap, Inc. Collimating fiber scanner design with inward pointing angles in virtual/augmented reality system
US10317690B2 (en) 2014-01-31 2019-06-11 Magic Leap, Inc. Multi-focal display system and method
US10338391B2 (en) 2015-10-06 2019-07-02 Magic Leap, Inc. Virtual/augmented reality system having reverse angle diffraction grating
US10587848B2 (en) 2016-01-20 2020-03-10 Magic Leap, Inc. Polarizing maintaining optical fiber in virtual/augmented reality system
US11016298B2 (en) 2015-10-05 2021-05-25 Magic Leap, Inc. Microlens collimator for scanning optical fiber in virtual/augmented reality system

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