[go: up one dir, main page]

UA6022A1 - СПОСІБ ОТРИМАННЯ ЦИКЛОАЛКОМЕДІВ (8-beta)-1АЛКІЛ-6-(ЗАМІЩЕНОГО) ЕРГОЛІНУ АБО ЇХ ФАРМАЦЕВТИЧНО ПРИДАТНИХ КИСЛОТНО-АДИТИВНИХ СОЛЕЙ - Google Patents

СПОСІБ ОТРИМАННЯ ЦИКЛОАЛКОМЕДІВ (8-beta)-1АЛКІЛ-6-(ЗАМІЩЕНОГО) ЕРГОЛІНУ АБО ЇХ ФАРМАЦЕВТИЧНО ПРИДАТНИХ КИСЛОТНО-АДИТИВНИХ СОЛЕЙ

Info

Publication number
UA6022A1
UA6022A1 UA4355904A UA4355904A UA6022A1 UA 6022 A1 UA6022 A1 UA 6022A1 UA 4355904 A UA4355904 A UA 4355904A UA 4355904 A UA4355904 A UA 4355904A UA 6022 A1 UA6022 A1 UA 6022A1
Authority
UA
Ukraine
Prior art keywords
ergoline
beta
substituted
preparation
cycloalcomedes
Prior art date
Application number
UA4355904A
Other languages
English (en)
Russian (ru)
Inventor
Мортенсен Форман Марк
Лі Гарбрехт Віллям
Ли Гарбрехт Виллям
Пурнелл Марзоні Джіффорд
Пурнелл Марзони Джиффорд
Роуз Віттен Кетлін
Роуз Виттен Кетлин
Original Assignee
Елі Ліллі Енд Компані
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Елі Ліллі Енд Компані, Эли Лилли Энд Компани filed Critical Елі Ліллі Енд Компані
Publication of UA6022A1 publication Critical patent/UA6022A1/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Спосіб одержання циклоалкіламідів (8С)-1-алкіл-6-(заміщеного) ерголіну загальної формули
UA4355904A 1987-06-15 1988-06-14 СПОСІБ ОТРИМАННЯ ЦИКЛОАЛКОМЕДІВ (8-beta)-1АЛКІЛ-6-(ЗАМІЩЕНОГО) ЕРГОЛІНУ АБО ЇХ ФАРМАЦЕВТИЧНО ПРИДАТНИХ КИСЛОТНО-АДИТИВНИХ СОЛЕЙ UA6022A1 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6228587A 1987-06-15 1987-06-15

Publications (1)

Publication Number Publication Date
UA6022A1 true UA6022A1 (uk) 1994-12-29

Family

ID=22041482

Family Applications (1)

Application Number Title Priority Date Filing Date
UA4355904A UA6022A1 (uk) 1987-06-15 1988-06-14 СПОСІБ ОТРИМАННЯ ЦИКЛОАЛКОМЕДІВ (8-beta)-1АЛКІЛ-6-(ЗАМІЩЕНОГО) ЕРГОЛІНУ АБО ЇХ ФАРМАЦЕВТИЧНО ПРИДАТНИХ КИСЛОТНО-АДИТИВНИХ СОЛЕЙ

Country Status (22)

Country Link
EP (1) EP0296748B1 (uk)
JP (1) JP2653835B2 (uk)
KR (1) KR960010454B1 (uk)
CN (1) CN1019451B (uk)
AT (1) ATE87921T1 (uk)
AU (1) AU613641B2 (uk)
CA (1) CA1339661C (uk)
DE (1) DE3880022T2 (uk)
DK (1) DK322588A (uk)
EG (1) EG18586A (uk)
ES (1) ES2054806T3 (uk)
HK (1) HK77693A (uk)
HU (2) HU203344B (uk)
IE (1) IE61884B1 (uk)
IL (1) IL86725A (uk)
MX (1) MX11866A (uk)
NZ (1) NZ225022A (uk)
PH (1) PH24309A (uk)
PT (1) PT87716B (uk)
SU (1) SU1597103A3 (uk)
UA (1) UA6022A1 (uk)
ZA (1) ZA884222B (uk)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902691A (en) * 1988-12-19 1990-02-20 Eli Lilly And Company Heteroalkylamides of (8-β)-1-alkyl-6-(substituted)ergolines useful for blocking 5HT2 receptors
IT1232692B (it) * 1989-08-04 1992-03-04 Poli Ind Chimica Spa Derivati ergolinici con attivita' dopaminergica
US5043341A (en) * 1990-04-11 1991-08-27 Eli Lilly And Company N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxamides
US5141944A (en) * 1990-04-11 1992-08-25 Eli Lilly And Company N-(2-hydroxycyclopentyl)-1-isopropyl-6-methylergoline-8-carboxamides
CA2218143A1 (en) * 1995-04-18 1996-10-24 Eli Lilly And Company Method for using ergoline compounds to effect physiological and pathological functions at the 5-ht7 receptor
US5880134A (en) * 1996-03-20 1999-03-09 Eli Lilly And Company Method for using ergoline compounds to effect physiological and pathological functions at the 5-HT7 receptor
EP0961148B1 (en) 1998-05-26 2010-07-21 Canon Kabushiki Kaisha Camera with focus detecting device
WO2011079313A1 (en) 2009-12-23 2011-06-30 Map Pharmaceuticals, Inc. Novel ergoline analogs
CN102775402B (zh) * 2011-05-13 2015-08-26 上海现代制药股份有限公司 一种制备二氢麦角酸的中间体及其制备方法
WO2012177962A1 (en) 2011-06-23 2012-12-27 Map Pharmaceuticals, Inc. Novel fluoroergoline analogs
WO2013095707A1 (en) 2011-12-19 2013-06-27 Map Pharmaceuticals, Inc. Novel iso-ergoline derivatives
WO2013095708A1 (en) 2011-12-21 2013-06-27 Map Pharmaceuticals, Inc. Novel neuromodulatory compounds
US9012640B2 (en) 2012-06-22 2015-04-21 Map Pharmaceuticals, Inc. Cabergoline derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH386441A (de) * 1961-02-17 1965-01-15 Sandoz Ag Verfahren zur Herstellung von am Indolstickstoff substituierten Derivaten der Lysergsäure-Reihe
GB982737A (en) * 1961-05-08 1965-02-10 Westminster Bank Ltd Improvements in or relating to lysergic acid compounds
GB996062A (en) * 1961-07-13 1965-06-23 Westminster Bank Ltd Improvements in or relating to lysergic acid compounds

Also Published As

Publication number Publication date
PH24309A (en) 1990-05-29
HU211235A9 (en) 1995-11-28
EG18586A (en) 1993-08-30
KR960010454B1 (ko) 1996-08-01
DE3880022T2 (de) 1993-08-19
PT87716A (pt) 1988-07-01
HU203344B (en) 1991-07-29
CN1030586A (zh) 1989-01-25
SU1597103A3 (ru) 1990-09-30
EP0296748B1 (en) 1993-04-07
AU1765288A (en) 1988-12-15
ES2054806T3 (es) 1994-08-16
CN1019451B (zh) 1992-12-16
DK322588D0 (da) 1988-06-14
IL86725A (en) 1993-01-14
DE3880022D1 (de) 1993-05-13
DK322588A (da) 1989-02-01
IL86725A0 (en) 1988-11-30
AU613641B2 (en) 1991-08-08
PT87716B (pt) 1992-10-30
JPS6416781A (en) 1989-01-20
MX11866A (es) 1993-12-01
JP2653835B2 (ja) 1997-09-17
EP0296748A1 (en) 1988-12-28
HUT47271A (en) 1989-02-28
ZA884222B (en) 1990-02-28
CA1339661C (en) 1998-02-10
IE61884B1 (en) 1994-11-30
NZ225022A (en) 1990-07-26
KR890000482A (ko) 1989-03-14
ATE87921T1 (de) 1993-04-15
HK77693A (en) 1993-08-13
IE881788L (en) 1988-12-15

Similar Documents

Publication Publication Date Title
PT87754A (pt) Process for the preparation of new amino acid derivatives
RO89082A (ro) Procedeu de preparare a unor derivati de acid ciclohexandion-carboxilic
PL272597A1 (en) Method for manufacturing new derivatives of 3-hydrobutyric acid
UA7083A1 (uk) Спосіб одержання похідних 1,4-дігідропірідіна або їх кислотно-адітивних солей
UA6022A1 (uk) СПОСІБ ОТРИМАННЯ ЦИКЛОАЛКОМЕДІВ (8-beta)-1АЛКІЛ-6-(ЗАМІЩЕНОГО) ЕРГОЛІНУ АБО ЇХ ФАРМАЦЕВТИЧНО ПРИДАТНИХ КИСЛОТНО-АДИТИВНИХ СОЛЕЙ
SU1181541A3 (ru) "cпocoб пoлучehия -зameщehhыx пpoизboдhыx aзиpидиh-2-kapбohoboй kиcлotы или иx coлeй"
PT87153A (pt) Process for the preparation of acid ribofuranuronic derivatives
PT83104A (en) Novel guanidinomethylbenzoic acid derivatives
FR2355796A1 (fr) Procede de preparation de fluorures d'acides perfluoro-alcoxy-propioniques
UA6330A1 (uk) Спосіб одержання похідних бензаміда
PT87854A (pt) Process for the preparation of thio-urea derivatives
PL238405A1 (en) Process for preparing novel derivatives of 2-aminocarboxylic acid
BG37991A3 (en) Method for stabilizing lyophylized preparation containing beta- lactamic antibiotic
PT88545A (pt) Process for the manufacture of benzimidazoline-2-oxo-1-carboxylic acid derivative compounds
FI890723A (fi) Menetelmä kinoliinikarboksyylihappojohdannaisten valmistamiseksi
GR1002384B (el) Μεθοδος παρασκευης παραγωγων υποκατεστημενου στυρολιου.
PT88681A (pt) A process for the preparation of pharmaceutical compositions containing piperidinoalkanol derivatives
FI883589A0 (fi) Menetelmä tyydyttämättömien aminohappoyhdisteiden valmistamiseksi
HUT49361A (en) Process for producing piperazinecarboxylic acid derivative and pharmaceutical compositions comprising this compound
YU141488A (en) Process for obtaining derivatives of hydrocimentic acid
IT1126544B (it) Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico
HUT48632A (en) Process for producing phosphinic acid derivatives
YU31285A (en) Process for producing salts of oxazaphosphorine derivatives
PT88116A (pt) Process for preparing naphthalenepropionic acid derivatives useful as anti-inflammatory/antiallergic agents
HUT49622A (en) Process for producing derivatives of phosphoric acid