TWM557589U - Blood glucose monitoring and control system - Google Patents

Abstract

A blood glucose monitoring and control system comprises: a detecting device and a liquid supply device, wherein the detecting device can detect the blood sugar level of the user by detecting the user's tissue fluid at any time, and when the blood sugar content of the user is abnormal, the detecting device is The liquid supply device is activated, so that the liquid supply device can immediately inject the insulin liquid into the user, adjust the blood sugar level of the user, and the user's blood sugar content can be in a stable state for a long time.

Description

Blood glucose monitoring and control system

This case relates to a blood glucose monitoring and control system, especially a blood glucose monitoring and control system capable of monitoring and controlling blood sugar content of a human body for a long time.

Self-testing of blood glucose plays a very important role in the management of blood sugar, but the blood glucose meter used to measure blood sugar is not easy to carry, so it is difficult for patients to detect blood sugar when they go out, and in the process of measuring blood sugar, Sometimes there is a needle but there is no bleeding or too little blood. Therefore, it is necessary to puncture the needle again or force the blood out, but re-needle may cause the patient to bear the burden. Extrusion of the blood may result in inaccurate measurement results. In addition, when the patient finds that the blood sugar is abnormal, it is difficult to take the oral medicine or the injection immediately, which may cause the blood sugar to be unable to maintain a stable state for a long time, which may easily cause complications and further harm the patient's body.

In view of the above-mentioned shortcomings, this project develops a safe, portable and painless intelligent blood glucose monitoring and control system, which provides patients with daily and easy measurement of blood sugar levels in daily life, and can stabilize blood sugar levels for a long time, and solve the problem that patients cannot stabilize blood sugar. problem.

In order to solve the problem that the traditional insulin injection method causes the patient to suffer from pain and inconvenience, the present invention provides a blood glucose monitoring and control system, comprising: a detecting device comprising a first microneedle patch, a sputum actuator, and a sense And a monitoring control chip, wherein the first microneedle patch has a plurality of hollow microneedles attached to the human skin to extract a tissue fluid, the sputum actuator is provided with a liquid guiding channel and a first actuation a unit, the liquid guiding channel is in communication with the first microneedle patch, the first actuating unit is actuated to cause the liquid guiding channel to form a pressure difference to extract the tissue fluid, and the liquid guiding channel is further drawn by the plurality of hollow micro The tissue fluid introduced by the needle, and the sensor is disposed in the catheter to monitor the blood glucose level value of the tissue fluid, and sent to the monitoring control chip to calculate a blood glucose value information, and send the blood glucose value information And a liquid supply device comprising a second microneedle patch, a liquid supply actuator, a liquid supply chamber and a liquid supply control chip, wherein the second microneedle patch has a plurality of hollow microneedles for insertion into a human skin, the liquid supply actuator being provided with a liquid injection channel and a second actuation unit, the liquid injection channel being in communication with the second microneedle patch, and The liquid supply chamber is connected, and the liquid supply chamber stores an insulin liquid. The second actuation unit is configured to actuate and compress the liquid injection channel for liquid transmission, and the liquid supply control chip receives the monitoring control chip of the detection device and sends the liquid. Notifying the blood glucose value information to activate the second actuation unit of the liquid supply device, causing the injection channel to form a pressure difference to transmit the insulin liquid stored in the liquid supply chamber, and introducing the same into the plurality of hollow microneedles The insulin liquid is injected into the subcutaneous tissue of the human body, and the balance required for blood sugar control is controlled.

Some exemplary embodiments embodying the features and advantages of the present invention are described in detail in the following description. It is to be understood that the present invention is capable of various modifications in various aspects, and is not to be construed as a limitation.

The present invention is a blood glucose monitoring and control system. Referring to FIG. 1 to FIG. 3, as shown in FIG. 1, the blood glucose monitoring and control system 100 includes a detecting device 1 and a liquid supply device 2; as shown in FIG. The detecting device 1 includes a first microneedle patch 11, a sputum actuator 12, a sensor 13 and a monitoring control chip 14; as shown in FIG. 3, the liquid supply device 2 includes a first The second microneedle patch 21, a liquid supply actuator 22, a liquid supply chamber 23 and a liquid supply control wafer 24, the detection device 1 detects the blood sugar level of the user, and the insulin supply device 2 provides insulin. The liquid, when the detecting device 1 detects that the blood sugar level of the user is abnormal, the liquid feeding device 2 is activated to inject the insulin liquid into the user's body to achieve the purpose of blood sugar monitoring and control.

Continuing to refer to FIG. 1 and FIG. 2, the sputum actuator 12 of the detecting device 1 of the present invention includes a liquid guiding channel 121, a first actuating unit 122, a first carrier 123, and a first The pressure chamber 124 and the liquid storage chamber 125 are recessed on the first carrier 123 to form a first pressure chamber 124, a liquid storage chamber 125, and a liquid guiding channel 121. The liquid guiding channel 121 further includes an inlet passage 121a. And a liquid storage channel 121b, which are disposed on the first carrier 123 spaced apart from each other and communicated through the first pressure chamber 124, and the liquid storage channel 121b communicates with the liquid storage chamber 125, and the sensor 13 is disposed In the liquid storage chamber 125, the liquid stored in the liquid storage chamber 125 is detected; and the first actuation unit 122 is constructed on the first carrier 123 and covers the first pressure chamber 124 when the first actuation After the unit 122 is actuated, a drawing force is generated for extracting the liquid; the first microneedle patch 11 is attached to the first carrier 123 and communicates with the inlet channel 121a, and has a plurality of hollow microneedles 111, a plurality of hollows. The microneedle 111 is inserted into the human skin through non-invasive or minimally invasive; and the sensor 13 and the monitoring control chip 14 are microelectromechanical processes (M The EMS is integrated on the first carrier 123, and the sensor 13 is packaged on the first carrier 123 through the system. The monitoring control chip 14 is also disposed on the first carrier 123 in a system package for controlling the sputum actuator 12. The data monitored by the sensor 13 is activated and received. The sputum actuator 12 is sealed by the first actuation unit 122 to seal the pressure chamber 124, and the first actuation unit 122 is driven to vibrate up and down to change the volume of the first pressure chamber 124 to make the first pressure chamber. 124 internal pressure changes to produce traction.

Referring to FIG. 1 and FIG. 8, in the embodiment, after the plurality of hollow microneedles 111 of the first microneedle patch 11 are stuck into the human body, the monitoring control wafer 14 drives the sputum actuator. The first actuation unit 122 of the 12 is vertically vibrated, expands and compresses the volume of the first pressure chamber 124 through the first actuation unit 122, changes the internal pressure to generate a suction force, generates suction force in the inlet passage 121a, and transmits the first microneedle. The hollow microneedle 111 of the patch 11 inhales the tissue fluid of the human body and flows through the first pressure chamber 124 and the reservoir channel 121b into the liquid storage chamber 125. At this time, the sensor 13 detects the blood glucose level value in the tissue fluid, and The monitoring control chip 14 is sent to calculate the blood glucose level information, and the monitoring control chip 14 has a transmission transmission module 141 for transmitting the notification of the blood glucose level information. Wherein, the tissue fluid is a tissue fluid under the skin of the human body, and the liquid supply device 2 also has a receiving and transmitting module 24 for receiving the notification of the blood glucose level information transmitted by the monitoring device 14 of the detecting device 1 to enable the liquid feeding control chip The liquid supply actuator 22 can be quickly activated to be transported to the insulin liquid in the liquid supply chamber 23 and injected into the user's body to stabilize the blood sugar level of the user.

Referring to FIG. 1 and FIG. 3, the liquid supply actuator 22 of the liquid supply device 2 of the present invention comprises a liquid injection channel 221, a second actuation unit 222, a second carrier 223 and a second pressure chamber. The chamber 224 is recessed on the second carrier 223 to form a second pressure chamber 224 and a liquid injection channel 221. The liquid injection channel 221 further includes a liquid outlet channel 221a and a liquid guiding channel 221b. The liquid is disposed on the second carrier 223 and communicates through the second pressure chamber 224, and the liquid guiding channel 221b communicates with the liquid supply chamber 23, the insulin liquid is stored in the liquid supply chamber 23, and has a liquid supply outlet 231 for supplying The liquid outlet 231 is provided with a valve switch 4 for controlling the outflow of the insulin liquid; the second microneedle patch 21 is attached to the second carrier 223 and communicates with the liquid outlet channel 221a, and has a plurality of hollow microneedles 211, a plurality of hollows. The microneedle 211 is used to inject insulin liquid through non-invasive or minimally invasive insertion into the human skin; and the liquid supply control wafer 24 is integrated with the micro-electromechanical process (MEMS) on the second carrier 223 for controlling the activation of the liquid supply actuator 22, In addition, the liquid supply control chip 24 has a receiving transmission module 241 (as shown in FIG. 8). The blood glucose value information transmitted by the transmission transmission module 141 of the monitoring control chip 14 of the detecting device 1 is received. The liquid supply actuator 22 seals the second pressure chamber 224 through the second actuation unit 222, and changes the volume of the second pressure chamber 224 by the actuation of the second actuation unit 222. The pressure inside the pressure chamber 224 changes in pressure difference to generate a discharge force for guiding the discharge of the insulin liquid.

Referring to FIG. 1 and FIG. 3, in the embodiment, when the plurality of hollow microneedles 211 of the second microneedle patch 21 are stuck into the human body, the liquid supply control chip 24 drives the liquid supply brake 22 The second actuation unit 222 vibrates vertically, expands and compresses the volume of the second pressure chamber 224 through the second brake unit 222, changes the internal pressure to generate a pressure difference to generate a discharge force, and passes the insulin liquid in the reservoir 125. The second pressure chamber 224 and the liquid injection channel 221 enter the second microneedle patch 21, and the insulin liquid is injected into the user from the plurality of hollow microneedles 211 on the second microneedle patch 21.

The plurality of hollow microneedles 111 of the first microneedle patch 11 or the plurality of hollow microneedles 211 of the second microneedle patch 21 are micron-sized pinholes capable of piercing the skin, and the material thereof may be a polymer. The polymer, metal or ruthenium is preferably a highly biocompatible ruthenium dioxide, and the pore size of the hollow microneedles 111, 211 is for the passage of insulin molecules, preferably, within the hollow microneedles 111, 211. The diameter is between 10 micrometers (μm) and 550 micrometers (μm), and the length of the hollow microneedles 111, 211 is between 400 micrometers (μm) and 900 micrometers (μm), which can be inserted into the subcutaneous tissue of the human body without penetration of the penetration depth. The human body is so nerve-free that it does not cause pain at all. The plurality of hollow microneedles 111 and 211 are arranged in an array on the first microneedle patch 11 and the second microneedle patch 21, and each of the hollow microneedles 111 and 211 is separated by more than 200. The micrometers do not interfere with each other, and the plurality of hollow microneedles 111, 211 arranged in such an array manner do not have the function of injecting fluid by blocking one of the hollow microneedles 111 and 211, and more than a plurality of The hollow microneedles 111, 211 act as an injection or extraction.

Continuing to refer to FIG. 2 and FIG. 4, the detecting device 1 of the blood glucose monitoring and control system 100 can respectively provide a valve plate 3 in the inlet passage 121a and the liquid storage passage 121b, and a plurality of valve holes 31 are formed on the valve plate 3, The first carrier 123 is respectively provided with a first convex portion structure 126a, 126b in the inlet passage 121a and the liquid storage passage 121b, wherein the first convex portion structure 126a and the first convex portion structure of the liquid storage passage 121b are disposed in the inlet passage 121a. The first convex portion structure 126a of the inlet passage 121a is upwardly convex, and the first convex portion structure 126b of the liquid storage passage 121b is downwardly convex, and the valve piece 3 is protruded in the opposite direction. A plurality of valve holes 31 are defined in a portion of the corresponding inlet passage 121a and the liquid storage passage 121b, and a central portion 32 is provided by a plurality of connecting portions 33, and a plurality of valve holes 31 are disposed at a plurality of connecting portions 33. The connecting portion 33 is provided with the central portion 32 elastically supported, so that the first protruding structures 126a, 126b of the inlet passage 121a and the liquid storage passage 121b abut against the valve plate 3 and close the valve hole 31 thereof. And produce a pre-force effect. With the above arrangement, when the first actuating unit 122 is not actuated, the central portion 32 of the valve plate 3 on the inlet passage 121a and the reservoir passage 121b can respectively close the inlet passage 121a and the reservoir passage 121b, thus The tissue fluid can be prevented from flowing back in the inlet passage 121a and the liquid storage passage 121b.

Please refer to FIG. 3 and FIG. 4 . The liquid supply device 2 of the blood glucose monitoring and control system 100 can also respectively provide a valve plate 3 in the liquid outlet channel 221 a and the liquid guiding channel 221 b , and a plurality of valve holes are formed on the valve plate 3 . 31, and the second carrier 223 is respectively provided with a second convex portion structure 226a, 226b in the liquid outlet channel 221a and the liquid guiding channel 221b, wherein the second convex portion structure 226a and the liquid guiding channel 221b are disposed in the liquid outlet channel 221a The second convex portion structure 226b protrudes in the opposite direction. In the embodiment, the second convex portion structure 226a located in the liquid inlet and outlet passage 221a protrudes downward, and the second convex portion structure 226b of the liquid guiding passage 221b protrudes upward. The valve plate 3 is also provided with a plurality of valve holes 31 in a portion of the corresponding liquid outlet passage 221a and the liquid guiding passage 221b, and a central portion 32 is connected by a plurality of connecting portions 33, and a plurality of valve holes 31 are provided. Between the plurality of connecting portions 33, the connecting portion 33 is provided with the central portion 32 elastically supported, so that the second protruding structures 226a, 226b of the liquid discharging passage 221a and the liquid guiding passage 221b are in close contact with the valve piece. 3, and close its valve hole 31, and generate a pre-force against the top use. With the above arrangement, when the second actuating unit 222 is not actuated, the central portion 32 of the valve plate 3 on the liquid outlet passage 221a and the liquid guiding passage 221b can respectively close the liquid outlet passage 221a and the liquid guiding passage 221b, In one case, the insulin liquid can be prevented from flowing back in the liquid outlet passage 221a and the liquid guiding passage 221b.

Referring to FIGS. 5A and 5B, after the sputum actuator 12 of the detecting device 1 is controlled by the monitoring control wafer 14, the first actuating unit 122 starts to flex up and down, first as shown in FIG. 5A. When the first actuating unit 122 is displaced upward, the volume of the first pressure chamber 124 increases, and a negative pressure is generated to drive the valve plate 3 of the inlet passage 121a to be displaced upward to make the valve hole 31 of the valve plate 3 (as shown in FIG. 4). The first protrusion structure 126a is separated from the first protrusion structure 126a. At this time, the inlet passage 121a and the first pressure chamber 124 are in communication, and the inlet pressure is generated due to the pressure difference change caused by the increase in the volume of the first pressure chamber 124. The microneedle patch 11 thus communicating with the inlet channel 121a also generates a suction force to draw into the tissue fluid, allowing the tissue fluid to enter the first pressure chamber 124 through the inlet channel 121a, and as shown in FIG. 5B, the monitoring control wafer 14 continues. The driving signal is output to the sputum actuator 12, and the first actuating unit 122 is displaced downward. At this time, the volume of the first pressure chamber 124 is lowered to generate a pressure difference change, and a positive pressure is generated to be pushed into the liquid storage channel 121b. The valve plate 3 moves downward and makes The valve hole 31 is separated from the first protrusion structure 126b, and the tissue fluid located in the first pressure chamber 124 is pushed into the liquid storage channel 121b by the positive pressure, and finally enters the liquid storage chamber 125, so that the tissue fluid is detected by the sensor 13. The blood glucose content value in the tissue fluid is sent to the monitoring control chip 14 to calculate the blood glucose value information. If the blood glucose value information is abnormal and the insulin needs to be supplemented, as shown in FIG. 8, the detecting device 1 can be monitored by the monitoring chip 14 The transmission transmission module 141 sends a notification of the blood glucose level information to the liquid supply device 2, and activates the liquid injection operation of the liquid supply device 2 to allow the user to supplement the insulin.

Referring to FIG. 6A, FIG. 6B and FIG. 8 again, when the liquid supply device 2 receives the notification of the blood glucose level information transmitted by the monitoring control chip 14 of the detecting device 1, the liquid supply control chip 24 can be quickly When the liquid supply actuator 22 is activated, the second actuation unit 222 starts to vibrate up and down. First, as shown in FIG. 6A, when the second actuation unit 222 is displaced upward, the volume of the second pressure chamber 224 increases and the pressure difference The change generates a negative pressure to drive the valve plate 3 of the liquid guiding passage 221b to be displaced upward, so that the valve hole 31 of the valve plate 3 (as shown in FIG. 4) is disengaged from the second convex portion structure 226a. At this time, the liquid guiding channel The second pressure chamber 224 is in communication with the second pressure chamber 224, and the pressure difference is changed due to the increase in the volume of the second pressure chamber 224, so that the liquid guiding channel 221b generates the drawing force, and the liquid supply control wafer 24 controls the valve of the liquid supply outlet 231. The switch 4 is opened, so that the insulin liquid in the liquid supply chamber 23 communicating with the liquid guiding channel 221b is sucked, so that the insulin liquid enters the second pressure chamber 224 through the liquid guiding channel 221b, and as shown in FIG. 6B, the liquid is supplied. The control chip 24 continuously outputs the driving signal to the liquid supply actuation The second actuating unit 222 is displaced downward. At this time, the volume of the second pressure chamber 224 is lowered to generate a pressure difference change, and the positive pressure is pushed to move the valve plate 3 in the liquid outlet passage 221a downward, and The valve hole 31 of the valve plate 3 (as shown in FIG. 4) is disengaged from the second protrusion structure 226b, and the insulin liquid in the second pressure chamber 224 is pushed into the liquid guiding channel 221a by the positive pressure, and then The plurality of hollow microneedles 211 of the second microneedle patch 21 inject insulin liquid into the user to stabilize the blood sugar level of the user.

Referring to FIGS. 3 and 7A, the valve switch 4 of the liquid supply chamber 23 of the liquid supply device 2 includes a holding member 41, a sealing member 42, and a displacement member 43. The displacement member 43 is disposed between the holder 41 and the sealing member 42. The holder 41, the sealing member 42 and the displacement member respectively have a plurality of through holes 44, and the plurality of through holes 44 of the holder 41 and the displacement member 43 are opposite each other. The seals 42 and the plurality of through holes 44 of the retaining member 41 are misaligned with each other.

Referring to FIG. 7A, the displacement member 43 is a charged material, and the holding member 41 is a two-polar conductive material, so that the displacement member 43 and the holder 41 maintain the same polarity, and the sealing member 42 is close to the sealing member 42. The valve switch 4 is closed; please refer to FIG. 7B, the displacement member 43 is a charged material, and the holder 41 is a two-polar conductive material, so that the displacement member 43 and the holder 41 maintain different polarities. The holder 41 is brought close to each other to constitute the opening of the valve switch 4, and the displacement member 43 is moved by adjusting the polarity of the holder 41 to form an open/close state of the valve switch 4. The holder 41 is controlled by the liquid supply control wafer 24 to have its polarity.

In addition, the displacement member 43 of the valve switch 4 described above may be a magnetic material, and the holder 41 is a magnetic material of controlled polarity. When the displacement member 43 and the holder 41 maintain the same polarity, the displacement member 43 faces The sealing member 42 is close to close the valve switch 4; conversely, when the holding member 41 changes polarity and has a different polarity from the displacement 43, the displacement member 43 will approach the holding member 41, and the valve switch 4 is configured to be opened. It is understood that the opening/closing state of the valve switch 4 is adjusted by adjusting the magnetic force of the holder 41 and moving the displacement member 43. The holder 41 is controlled by the liquid supply control wafer 24 to have its magnetic pole polarity.

As shown in FIG. 8, the transmission transmission module 141 and the reception transmission module 241 of the present embodiment can be transmitted via a cable, such as a wired transmission module such as USB, mini-USB, or micro-USB, or Wireless transmission, such as Wi-Fi module, Bluetooth module, radio frequency identification module, and a near field communication module.

In summary, the blood glucose monitoring and control system provided in the present case, when the first microneedle patch of the detecting device penetrates into the subcutaneous tissue of the human body, generates a pressure gradient through the action of the sputum actuator, so that the first microneedle The plurality of hollow microneedles in the patch generate a suction force to absorb the tissue fluid of the subcutaneous tissue, and then enter the liquid storage chamber through the first actuator, and the blood glucose content in the tissue fluid is detected by a sensor located in the liquid storage chamber to analyze the blood sugar. Information, and the blood sugar information is transmitted to the monitoring control chip. When the current blood sugar content of the user is abnormal, the monitoring control chip transmits and transmits the blood sugar value information to the liquid supply control wafer of the liquid supply device, so that the liquid supply control chip can be actuated immediately. The liquid supply actuator is used to instantly inject the insulin liquid into the user to maintain the stable blood sugar level, and the blood glucose monitoring and control system of the present invention can easily and simply measure the blood sugar at any time and anywhere, thereby reducing the user's measurement of blood sugar, and When the blood sugar level is abnormal, the insulin liquid can be quickly injected, and the blood sugar level can be maintained for a long time, and the diabetes can be overcome. Patients currently can not be long-term, effective to maintain a stable blood sugar. In addition, in this case, micro-needle patch is used to detect blood sugar by using non-invasive or minimally invasive tissue fluid to obtain subcutaneous tissue, which can reduce the burden on the user, avoid the occurrence of wounds and reduce the risk of infection.

This case has been modified by people who are familiar with the technology, but it is not intended to be protected by the scope of the patent application.

100‧‧‧ Blood glucose monitoring and control system
1‧‧‧Detection device
11‧‧‧First microneedle patch
111‧‧‧ hollow microneedles
12‧‧‧Sputum actuator
121‧‧‧ catheter channel
121a‧‧ Entrance Channel
121b‧‧‧ liquid storage channel
122‧‧‧First actuating unit
123‧‧‧First carrier
124‧‧‧First pressure chamber
125‧‧‧Liquid chamber
126a, 126b‧‧‧ first protruding structure
13‧‧‧ sensor
14‧‧‧Monitoring and Control Films
141‧‧‧Transmission transmission module
2‧‧‧Liquid supply device
21‧‧‧Second microneedle patch
211‧‧‧ hollow microneedles
22‧‧‧ Liquid supply actuator
221‧‧‧Infusion channel
221a‧‧‧Drain channel
221b‧‧‧ catheter
222‧‧‧Second actuating unit
223‧‧‧second carrier
224‧‧‧Second pressure chamber
226a, 226b‧‧‧second protruding structure
23‧‧‧Liquid supply room
24‧‧‧ Liquid supply control chip
241‧‧‧Receive transmission module
3‧‧‧ valve
31‧‧‧ valve hole
32‧‧‧Central Department
33‧‧‧Connecting Department
4‧‧‧Valve switch
41‧‧‧ Holder
42‧‧‧Seal
43‧‧‧ displacement parts
44‧‧‧through hole

Figure 1 is a schematic diagram of the use of the blood glucose monitoring and control system of the present case. Figure 2 is a schematic view showing the structure of the detecting device of the blood glucose monitoring and control system of the present invention. Figure 3 is a schematic view showing the structure of the liquid supply device of the blood glucose monitoring and control system of the present invention. Fig. 4 is a schematic view showing the structure of the valve piece of the blood glucose monitoring and control system of the present case. Fig. 5A and Fig. 5B are diagrams showing the operation of the blood glucose detecting device of the blood glucose monitoring and control system of the present invention shown in Fig. 2. Fig. 6A and Fig. 6B are diagrams showing the operation of the liquid supply device of the blood glucose monitoring and control system of the present invention shown in Fig. 3. Fig. 7A and Fig. 7B are schematic diagrams showing the operation of the valve switch of the blood glucose monitoring and control system of the present invention. Figure 8 is a block diagram showing the electrical connection relationship of related components of the blood glucose monitoring and control system of the present invention.

Claims (21)

A blood glucose monitoring and control system comprising: a detecting device comprising a first microneedle patch, a sputum actuator, a sensor and a monitoring control chip, wherein the first microneedle patch has a plurality of a hollow microneedle, which is attached to the human skin to capture a tissue fluid, the sputum actuator is provided with a liquid guiding channel and a first actuating unit, and the liquid guiding channel is in communication with the first microneedle patch, the first Actuating the unit to actuate the liquid guiding channel to form a pressure difference to draw the tissue fluid, and also to cause the liquid guiding channel to draw the tissue fluid introduced by the plurality of hollow microneedles, and the sensor is disposed in the catheter channel And monitoring the blood glucose content value of the tissue fluid, and transmitting to the monitoring control chip to calculate a blood glucose value information and transmitting the blood glucose value information notification; and a liquid supply device comprising a second microneedle patch, a liquid supply actuator, a liquid supply chamber and a liquid supply control wafer, wherein the second microneedle patch has a plurality of hollow microneedles for attachment into human skin, and the liquid supply actuator is provided with a liquid injection Channel and one a second actuation unit, the liquid injection channel is in communication with the second microneedle patch and is in communication with the liquid supply chamber, and the liquid supply chamber stores an insulin liquid, and the second actuation unit compresses the liquid injection channel by actuation Performing a liquid transfer, and the liquid supply control chip receives the notification of the blood glucose level information sent by the monitoring control chip of the detecting device to actuate the second actuating unit of the liquid supply device to form a pressure difference between the liquid injection channel The insulin liquid stored in the liquid supply chamber is transported and introduced into the plurality of hollow microneedles to inject the insulin liquid into the subcutaneous tissue of the human body to control the balance required for blood sugar. The blood glucose monitoring and control system of claim 1, wherein the sputum actuator of the detecting device further comprises a first carrier, a first pressure chamber and a liquid storage chamber, the liquid guiding channel An inlet channel and a liquid storage channel are disposed apart from each other on the first carrier, and the first pressure chamber communicates with the inlet channel and the liquid storage channel, and the liquid storage channel is connected to the liquid storage chamber, A sensor is disposed in the liquid storage chamber. The blood glucose monitoring and control system of claim 2, wherein the first actuating unit covers the first pressure chamber for actuating and compressing the liquid guiding channel, and is captured by the plurality of hollow microneedles The tissue fluid is introduced into the reservoir. The blood glucose monitoring and control system of claim 2, wherein the monitoring control chip is systematically packaged on the first carrier to control actuation of the first actuation unit of the sputum actuator and to receive the sensation The monitoring value of the detector is calculated to calculate the blood glucose value information, and has a transmission transmission module to send the notification of the blood glucose value information. The blood glucose monitoring and control system of claim 4, wherein the transmitting transmission module is at least a Wi-Fi module, a Bluetooth module, a radio frequency identification module, and a near field communication module. One of the wireless transmission modules. The blood glucose monitoring and control system of claim 2, wherein the inlet channel and the liquid storage channel are further provided with a valve plate for controlling the switching state of the inlet channel and the liquid storage channel. The blood glucose monitoring and control system of claim 6, wherein the first carrier has a convex structure at the inlet passage and the liquid storage passage to generate a pre-force to contact the valve plate to prevent the The tissue fluid is countercurrent. The blood glucose monitoring and control system of claim 1, wherein the liquid supply actuator further comprises a second carrier, a second pressure chamber and a liquid supply chamber, the liquid injection channel comprising a liquid outlet channel and a liquid guiding channel are disposed apart from each other on the second carrier, the second pressure chamber communicates with the liquid outlet channel and the liquid guiding channel, and the liquid guiding channel is connected to the liquid supply chamber, The second actuating unit covers the second pressure chamber for actuation to cause a pressure difference between the liquid injection channel, and the insulin liquid stored in the liquid supply chamber is introduced into the plurality of hollow microneedles. The blood glucose monitoring and control system of claim 8, wherein a valve plate is further disposed in the liquid outlet channel and the liquid guiding channel for controlling the switching state of the liquid outlet channel and the liquid guiding channel. The blood glucose monitoring and control system of claim 9, wherein the second carrier has a convex structure at the liquid outlet channel and the liquid guiding channel to generate a pre-force to contact the valve plate to prevent The insulin liquid is countercurrent. The blood glucose monitoring and control system of claim 8, wherein the liquid supply control chip of the liquid supply device is packaged on the second carrier by a system, and has a receiving transmission module for receiving the detection. The monitoring of the device controls the notification of the blood glucose value information sent by the wafer to control the activation of the second actuation unit of the liquid supply device. The blood glucose monitoring and control system of claim 11, wherein the receiving transmission module is at least a Wi-Fi module, a Bluetooth module, a radio frequency identification module, and a near field communication module. One of the wireless transmission modules. The blood glucose monitoring and control system of claim 1, wherein each of the plurality of hollow microneedles of the first microneedle patch and the second microneedle patch has an inner diameter of 10 micrometers to 550 microns, length between 400 microns and 900 microns. The blood glucose monitoring and control system of claim 1, wherein the plurality of hollow microneedles of the first microneedle patch and the second microneedle patch are arranged in an array, and the plurality of hollow microneedles Each of them is adjacent to each other by more than 200 microns. The blood glucose monitoring and control system of claim 1, wherein the plurality of hollow microneedles of the first microneedle patch and the second microneedle patch are made of a cerium oxide material. The blood glucose monitoring and control system according to claim 1, wherein the liquid supply chamber has a liquid supply outlet, and the liquid supply outlet is provided with a valve switch, wherein the valve switch comprises a holding member, a sealing member and a displacement member. The displacement member is disposed between the holding member and the sealing member, and the holding member, the sealing member and the displacement member respectively have a plurality of through holes, and the holding member and the displacement member have a plurality of through holes The positions are aligned with each other, and the plurality of through hole positions of the seal and the holder are misaligned to form a misalignment. The blood glucose monitoring and control system of claim 16, wherein the displacement member is a charged material, and the holder is a two-polar conductive material to maintain the displacement member and the holder in different polarities. And approaching the holder, the opening of the valve switch is formed. The blood glucose monitoring and control system of claim 16, wherein the displacement member is a charged material, and the holder is a two-polar conductive material to maintain the same polarity of the displacement member and the holder. Adjacent to the seal, the valve switch is closed. The blood glucose monitoring and control system according to claim 16, wherein the displacement member is a magnetic material, and the holding member is a magnetic material of controlled polarity, so that the displacement member and the holder are maintained. Different polarity, and approaching the holder, constitutes the opening of the valve switch. The blood glucose monitoring and control system according to claim 16, wherein the displacement member is a magnetic material, and the holding member is a magnetic material of controlled polarity, so that the displacement member and the holder are maintained. The same polarity, and approaching the seal, constitutes the closing of the valve switch. The blood glucose monitoring control system according to any one of claims 17 to 19, wherein the holder controls the polarity of the liquid supply control wafer.