TW200505852A - Novel compounds - Google Patents

Novel compounds

Info

Publication number: TW200505852A
Authority: TW; Taiwan
Prior art keywords: 4alkyl; 6alkyl; aryl; het; scf3
Prior art date: 2003-06-17

Application number

TW093117317A

Other languages

English (en)

Inventor

Paul Vincent Fish

Michael Jonathan Fray

Deborah Jane Lovering

Alan Stobie

Florian Wakenhut

Gavin Alistair Whitlock

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-17

Filing date

2004-06-16

Publication date

2005-02-16

2003-06-17 Priority claimed from GBGB0314048.0A external-priority patent/GB0314048D0/en

2004-06-16 Application filed by Pfizer filed Critical Pfizer

2005-02-16 Publication of TW200505852A publication Critical patent/TW200505852A/zh

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Addiction (AREA)
Psychology (AREA)
Gynecology & Obstetrics (AREA)
Epidemiology (AREA)
Obesity (AREA)
Anesthesiology (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

TW093117317A 2003-06-17 2004-06-16 Novel compounds TW200505852A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0314048.0A GB0314048D0 (en)	2003-06-17	2003-06-17	Novel compounds
US49312603P	2003-08-06	2003-08-06

Publications (1)

Publication Number	Publication Date
TW200505852A true TW200505852A (en)	2005-02-16

Family

ID=33554153

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW093117317A TW200505852A (en)	2003-06-17	2004-06-16	Novel compounds

Country Status (31)

Country	Link
US (2)	US7378436B2 (zh)
EP (1)	EP1638933B1 (zh)
JP (1)	JP4137159B2 (zh)
KR (1)	KR100803796B1 (zh)
AP (1)	AP2005003467A0 (zh)
AR (1)	AR044715A1 (zh)
AT (1)	ATE398107T1 (zh)
AU (1)	AU2004247487B2 (zh)
BR (1)	BRPI0411594A (zh)
CA (1)	CA2530159C (zh)
CY (1)	CY1110434T1 (zh)
DE (1)	DE602004014372D1 (zh)
DK (1)	DK1638933T3 (zh)
EA (1)	EA009881B1 (zh)
EC (1)	ECSP056232A (zh)
ES (1)	ES2305776T3 (zh)
HR (2)	HRP20050993A2 (zh)
IL (1)	IL172063A0 (zh)
IS (1)	IS8136A (zh)
MA (1)	MA27885A1 (zh)
MX (1)	MXPA05013960A (zh)
NL (1)	NL1026438C2 (zh)
NZ (1)	NZ544046A (zh)
PA (1)	PA8605301A1 (zh)
PE (1)	PE20050631A1 (zh)
PL (1)	PL1638933T3 (zh)
PT (1)	PT1638933E (zh)
SI (1)	SI1638933T1 (zh)
TW (1)	TW200505852A (zh)
UY (1)	UY28360A1 (zh)
WO (1)	WO2004110995A1 (zh)

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US7122683B2 (en)	2004-11-23	2006-10-17	Pfizer Inc.	Amides useful as monoamine re-uptake inhibitors
GB0425766D0 (en) *	2004-11-23	2004-12-22	Pfizer Ltd	Novel compounds
CA2590229A1 (en) *	2004-12-14	2006-06-22	Pfizer Limited	N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenalin re-uptake inhibitors
WO2006064332A1 (en) *	2004-12-14	2006-06-22	Pfizer Limited	N-pyrrolidin-3yl-amide derivatives as serotonin and noradrenalin re-uptake inhibitors
TWI439452B (zh) *	2005-05-13	2014-06-01	Otsuka Pharma Co Ltd	吡咯烷化合物（二）
ES2330788T3 (es)	2005-06-02	2009-12-15	F. Hoffmann-La Roche Ag	Derivados de piperidin-4-il-amida y su uso como antagonistas del subtipo 5 del receptor sst.
WO2007135530A2 (en) *	2006-05-22	2007-11-29	Pfizer Limited	Pharmaceutically & veterinarily suitable salt
US20080014152A1 (en) *	2006-07-13	2008-01-17	Di Mauro Thomas M	Intranasal delivery of clenbuterol across the cribriform plate and into the brain
JP5219465B2 (ja) *	2006-11-10	2013-06-26	大塚製薬株式会社	医薬
US20100056497A1 (en) *	2007-01-31	2010-03-04	Dainippon Sumitomo Pharma Co., Ltd	Amide derivative
JP2010189275A (ja) *	2007-06-14	2010-09-02	Dainippon Sumitomo Pharma Co Ltd	ナフタレン誘導体
US8263652B2 (en)	2007-10-31	2012-09-11	Sk Biopharmaceuticals Co., Ltd.	Stabilized pediatric suspension of carisbamate
US8389511B2 (en)	2007-12-19	2013-03-05	Dainippon Sumitomo Pharma Co., Ltd.	Bicyclic heterocyclic derivative
US7888386B2 (en)	2008-07-24	2011-02-15	Theravance, Inc.	3-(phenoxyphenylmethyl)pyrrolidine compounds
TWI443087B (zh)	2008-11-14	2014-07-01	Theravance Inc	４－〔２－（２－氟苯氧基甲基）苯基〕哌啶化合物
WO2010120910A1 (en) *	2009-04-15	2010-10-21	Theravance, Inc.	3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds
WO2010150840A1 (ja)	2009-06-24	2010-12-29	大日本住友製薬株式会社	Ｎ－置換－環状アミノ誘導体
US7994209B2 (en) *	2009-07-13	2011-08-09	Theravance, Inc.	3-phenoxymethylpyrrolidine compounds
US8273786B2 (en) *	2009-07-21	2012-09-25	Theravance, Inc.	3-phenoxymethylpyrrolidine compounds
JP5705239B2 (ja)	2010-01-11	2015-04-22	セラヴァンスバイオファーマアール＆ディーアイピー，エルエルシー	セロトニンおよびノルエピネフリン再取込みインヒビターとしての１−（２−フェノキシメチルフェニル）ピペラジン化合物
US8530663B2 (en) *	2010-03-22	2013-09-10	Theravance, Inc.	1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds
EP2627630B1 (en)	2010-10-11	2014-12-31	Theravance Biopharma R&D IP, LLC	Serotonin reuptake inhibitors
WO2012075239A1 (en)	2010-12-03	2012-06-07	Theravance, Inc.	Serotonin reuptake inhibitors

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DK1638933T3 (da) *	2003-06-17	2008-07-28	Pfizer	N-pyrrolidin-3-yl-amid-derivater som serotonin- og noradrenalin-genoptagelses inhibitorer

2004
- 2004-06-07 DK DK04736241T patent/DK1638933T3/da active
- 2004-06-07 KR KR1020057024147A patent/KR100803796B1/ko not_active Expired - Fee Related
- 2004-06-07 JP JP2006516540A patent/JP4137159B2/ja not_active Expired - Fee Related
- 2004-06-07 DE DE602004014372T patent/DE602004014372D1/de not_active Expired - Lifetime
- 2004-06-07 NZ NZ544046A patent/NZ544046A/en unknown
- 2004-06-07 WO PCT/IB2004/001943 patent/WO2004110995A1/en active IP Right Grant
- 2004-06-07 MX MXPA05013960A patent/MXPA05013960A/es active IP Right Grant
- 2004-06-07 CA CA002530159A patent/CA2530159C/en not_active Expired - Fee Related
- 2004-06-07 SI SI200430767T patent/SI1638933T1/sl unknown
- 2004-06-07 AT AT04736241T patent/ATE398107T1/de not_active IP Right Cessation
- 2004-06-07 EA EA200501730A patent/EA009881B1/ru not_active IP Right Cessation
- 2004-06-07 EP EP04736241A patent/EP1638933B1/en not_active Expired - Lifetime
- 2004-06-07 PT PT04736241T patent/PT1638933E/pt unknown
- 2004-06-07 PL PL04736241T patent/PL1638933T3/pl unknown
- 2004-06-07 AU AU2004247487A patent/AU2004247487B2/en not_active Expired - Fee Related
- 2004-06-07 AP AP2005003467A patent/AP2005003467A0/xx unknown
- 2004-06-07 ES ES04736241T patent/ES2305776T3/es not_active Expired - Lifetime
- 2004-06-07 BR BRPI0411594-5A patent/BRPI0411594A/pt not_active IP Right Cessation
- 2004-06-14 PE PE2004000590A patent/PE20050631A1/es not_active Application Discontinuation
- 2004-06-14 UY UY28360A patent/UY28360A1/es not_active Application Discontinuation
- 2004-06-16 PA PA20048605301A patent/PA8605301A1/es unknown
- 2004-06-16 TW TW093117317A patent/TW200505852A/zh unknown
- 2004-06-16 AR ARP040102082A patent/AR044715A1/es not_active Application Discontinuation
- 2004-06-17 US US10/872,160 patent/US7378436B2/en not_active Expired - Fee Related
- 2004-06-17 NL NL1026438A patent/NL1026438C2/nl not_active IP Right Cessation
2005
- 2005-11-20 IL IL172063A patent/IL172063A0/en unknown
- 2005-11-21 IS IS8136A patent/IS8136A/is unknown
- 2005-12-14 HR HR20050993A patent/HRP20050993A2/hr not_active Application Discontinuation
- 2005-12-16 EC EC2005006232A patent/ECSP056232A/es unknown
- 2005-12-16 MA MA28674A patent/MA27885A1/fr unknown
2008
- 2008-05-21 US US12/124,755 patent/US20080306123A1/en not_active Abandoned
- 2008-07-09 HR HR20080339T patent/HRP20080339T3/xx unknown
- 2008-08-14 CY CY20081100869T patent/CY1110434T1/el unknown

Also Published As

Publication number	Publication date
HRP20050993A2 (en)	2006-03-31
EA009881B1 (ru)	2008-04-28
WO2004110995A8 (en)	2005-04-21
CY1110434T1 (el)	2015-04-29
MXPA05013960A (es)	2006-02-24
CA2530159C (en)	2010-02-02
HRP20080339T3 (en)	2008-08-31
KR100803796B1 (ko)	2008-02-14
NL1026438C2 (nl)	2005-09-20
ES2305776T3 (es)	2008-11-01
KR20060036927A (ko)	2006-05-02
US20080306123A1 (en)	2008-12-11
US7378436B2 (en)	2008-05-27
AU2004247487B2 (en)	2010-05-20
CA2530159A1 (en)	2004-12-23
US20050137229A1 (en)	2005-06-23
AU2004247487A1 (en)	2004-12-23
NL1026438A1 (nl)	2004-12-20
PL1638933T3 (pl)	2008-10-31
NZ544046A (en)	2009-08-28
IL172063A0 (en)	2009-02-11
JP4137159B2 (ja)	2008-08-20
AR044715A1 (es)	2005-09-21
ECSP056232A (es)	2006-04-19
ATE398107T1 (de)	2008-07-15
UY28360A1 (es)	2005-01-31
EP1638933B1 (en)	2008-06-11
EP1638933A1 (en)	2006-03-29
PA8605301A1 (es)	2005-02-04
WO2004110995A1 (en)	2004-12-23
AP2005003467A0 (en)	2006-12-31
EA200501730A1 (ru)	2006-08-25
DE602004014372D1 (de)	2008-07-24
PE20050631A1 (es)	2005-09-14
MA27885A1 (fr)	2006-05-02
JP2006527758A (ja)	2006-12-07
IS8136A (is)	2005-11-21
PT1638933E (pt)	2008-07-22
BRPI0411594A (pt)	2006-08-29
SI1638933T1 (sl)	2008-10-31
DK1638933T3 (da)	2008-07-28

Publication	Publication Date	Title
TW200505852A (en)	2005-02-16	Novel compounds
WO2005097129A3 (en)	2006-01-19	6-azaindole compound
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