HRP20080339T3 - N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors - Google Patents

N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors

Info

Publication number: HRP20080339T3
Authority: HR; Croatia
Prior art keywords: alkyl; aryl; alkoxy; het; heteroatom
Prior art date: 2003-06-17

Application number

HR20080339T

Other languages

English (en)

Croatian (hr)

Inventor

Vincent Fish Paul

Jonathan Fray Michael

Stobie Alan

Wakenhut Florian

Alistair Whitlock Gavin

Daniel Brown Alan

David Andrews Mark

Ian Lansdell Mark

Original Assignee

Pfizer Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-06-17

Filing date

2004-06-07

Publication date

2008-08-31

2003-06-17 Priority claimed from GBGB0314048.0A external-priority patent/GB0314048D0/en

2004-06-07 Application filed by Pfizer Inc. filed Critical Pfizer Inc.

2008-08-31 Publication of HRP20080339T3 publication Critical patent/HRP20080339T3/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Psychology (AREA)
Gynecology & Obstetrics (AREA)
Obesity (AREA)
Child & Adolescent Psychology (AREA)
Rheumatology (AREA)
Anesthesiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)

HR20080339T 2003-06-17 2004-06-07 N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors HRP20080339T3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB0314048.0A GB0314048D0 (en)	2003-06-17	2003-06-17	Novel compounds
US49312603P	2003-08-06	2003-08-06
PCT/IB2004/001943 WO2004110995A1 (en)	2003-06-17	2004-06-07	N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors

Publications (1)

Publication Number	Publication Date
HRP20080339T3 true HRP20080339T3 (en)	2008-08-31

Family

ID=33554153

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HR20050993A HRP20050993A2 (en)	2003-06-17	2004-06-07	N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors
HR20080339T HRP20080339T3 (en)	2003-06-17	2004-06-07	N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
HR20050993A HRP20050993A2 (en)	2003-06-17	2004-06-07	N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenaline re-uptake inhibitors

Country Status (31)

Country	Link
US (2)	US7378436B2 (xx)
EP (1)	EP1638933B1 (xx)
JP (1)	JP4137159B2 (xx)
KR (1)	KR100803796B1 (xx)
AP (1)	AP2005003467A0 (xx)
AR (1)	AR044715A1 (xx)
AT (1)	ATE398107T1 (xx)
AU (1)	AU2004247487B2 (xx)
BR (1)	BRPI0411594A (xx)
CA (1)	CA2530159C (xx)
CY (1)	CY1110434T1 (xx)
DE (1)	DE602004014372D1 (xx)
DK (1)	DK1638933T3 (xx)
EA (1)	EA009881B1 (xx)
EC (1)	ECSP056232A (xx)
ES (1)	ES2305776T3 (xx)
HR (2)	HRP20050993A2 (xx)
IL (1)	IL172063A0 (xx)
IS (1)	IS8136A (xx)
MA (1)	MA27885A1 (xx)
MX (1)	MXPA05013960A (xx)
NL (1)	NL1026438C2 (xx)
NZ (1)	NZ544046A (xx)
PA (1)	PA8605301A1 (xx)
PE (1)	PE20050631A1 (xx)
PL (1)	PL1638933T3 (xx)
PT (1)	PT1638933E (xx)
SI (1)	SI1638933T1 (xx)
TW (1)	TW200505852A (xx)
UY (1)	UY28360A1 (xx)
WO (1)	WO2004110995A1 (xx)

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US7868014B2 (en)	2004-10-18	2011-01-11	Eli Lilly And Company	1-(hetero)aryl-3-amino-pyrrolidine derivatives for use as mGluR3 antagonists
GB0425766D0 (en) *	2004-11-23	2004-12-22	Pfizer Ltd	Novel compounds
US7122683B2 (en)	2004-11-23	2006-10-17	Pfizer Inc.	Amides useful as monoamine re-uptake inhibitors
EP1828119A1 (en) *	2004-12-14	2007-09-05	Pfizer Limited	N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenalin re-uptake inhibitors
CA2590229A1 (en) *	2004-12-14	2006-06-22	Pfizer Limited	N-pyrrolidin-3-yl-amide derivatives as serotonin and noradrenalin re-uptake inhibitors
TWI449692B (zh)	2005-05-13	2014-08-21	Otsuka Pharma Co Ltd	吡咯烷化合物（三）
EP1893603B1 (en) *	2005-06-02	2009-10-14	F. Hoffmann-La Roche AG	Piperidin-4-yl-amide derivatives and their use as sst receptor subtype 5 antagonists
WO2007135530A2 (en) *	2006-05-22	2007-11-29	Pfizer Limited	Pharmaceutically & veterinarily suitable salt
US20080014152A1 (en) *	2006-07-13	2008-01-17	Di Mauro Thomas M	Intranasal delivery of clenbuterol across the cribriform plate and into the brain
JP5219465B2 (ja) *	2006-11-10	2013-06-26	大塚製薬株式会社	医薬
EP2119702A4 (en) *	2007-01-31	2010-12-08	Dainippon Sumitomo Pharma Co	amide derivative
JP2010189275A (ja) *	2007-06-14	2010-09-02	Dainippon Sumitomo Pharma Co Ltd	ナフタレン誘導体
US8263652B2 (en)	2007-10-31	2012-09-11	Sk Biopharmaceuticals Co., Ltd.	Stabilized pediatric suspension of carisbamate
TWI434690B (zh)	2007-12-19	2014-04-21	Dainippon Sumitomo Pharma Co	雜雙環衍生物
JP5405571B2 (ja)	2008-07-24	2014-02-05	セラヴァンス，インコーポレーテッド	３−（フェノキシフェニルメチル）ピロリジン化合物
RU2515612C2 (ru)	2008-11-14	2014-05-20	Тереванс, Инк.	4-[2-(2-фторфеноксиметил)фенил]пиперидиновые соединения
WO2010120910A1 (en) *	2009-04-15	2010-10-21	Theravance, Inc.	3-(phenoxypyrrolidin-3-yl-methyl)heteroaryl, 3-(phenylpyrrolidin-3-ylmethoxy)heteroaryl, and 3-(heteroarylpyrrolidin-3-ylmethoxy)heteroaryl compounds
JP5331883B2 (ja)	2009-06-24	2013-10-30	大日本住友製薬株式会社	Ｎ−置換−環状アミノ誘導体
AU2010273645B2 (en)	2009-07-13	2014-12-04	Theravance Biopharma R&D Ip, Llc	3-phenoxymethylpyrrolidine compounds
JP5714580B2 (ja)	2009-07-21	2015-05-07	セラヴァンスバイオファーマアール＆ディーアイピー，エルエルシー	３−フェノキシメチルピロリジン化合物
JP5705239B2 (ja)	2010-01-11	2015-04-22	セラヴァンスバイオファーマアール＆ディーアイピー，エルエルシー	セロトニンおよびノルエピネフリン再取込みインヒビターとしての１−（２−フェノキシメチルフェニル）ピペラジン化合物
US8530663B2 (en) *	2010-03-22	2013-09-10	Theravance, Inc.	1-(2-phenoxymethylheteroaryl)piperidine and piperazine compounds
JP5873877B2 (ja)	2010-10-11	2016-03-01	セラヴァンスバイオファーマアール＆ディーアイピー，エルエルシー	セロトニン再取込みインヒビター
WO2012075239A1 (en)	2010-12-03	2012-06-07	Theravance, Inc.	Serotonin reuptake inhibitors

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JP2003525903A (ja)	2000-03-03	2003-09-02	エーザイ株式会社	コリンエステラーゼ阻害剤の新規使用法
NZ520240A (en) *	2000-03-06	2005-04-29	Acadia Pharm Inc	Azacyclic compounds for use in the treatment of serotonin related diseases
EP1319001A1 (en)	2000-09-22	2003-06-18	Smithkline Beecham Plc	Pyrazolopyridines and pyrazolopyridazines as antidiabetics
KR20030029978A (ko)	2000-09-25	2003-04-16	액테리온 파마슈티칼 리미티드	말라리아에 유용한 치환된 아미노-아자-사이클로알칸
EP1430027B1 (en)	2001-09-14	2010-09-01	High Point Pharmaceuticals, LLC	Novel aminoazetidine, -pyrrolidine and -piperidine derivatives
CA2468761A1 (en)	2001-10-31	2003-05-08	Morphochem Aktiengesellschaft Fuer Kombinatorische Chemie	Novel anticancer compounds
GB0128287D0 (en)	2001-11-26	2002-01-16	Smithkline Beecham Plc	Novel method and compounds
CA2490397A1 (en) *	2002-06-24	2003-12-31	Acadia Pharmaceuticals Inc.	N-substituted piperidine derivatives as serotonin receptor agents
WO2004009549A2 (en)	2002-07-18	2004-01-29	Actelion Pharmaceuticals Ltd	Piperidines useful for the treatment of central nervous system disorders
WO2004022536A1 (en)	2002-09-04	2004-03-18	Glenmark Pharmaceuticals Limited	New heterocyclic amide compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them
WO2004058705A2 (en)	2002-12-20	2004-07-15	Chemocentryx	Inhibitors of the binding of chemokines i-tac or sdf-1 to the ccxckr2 receptor
DK1638933T3 (da) *	2003-06-17	2008-07-28	Pfizer	N-pyrrolidin-3-yl-amid-derivater som serotonin- og noradrenalin-genoptagelses inhibitorer

2004
- 2004-06-07 DK DK04736241T patent/DK1638933T3/da active
- 2004-06-07 HR HR20050993A patent/HRP20050993A2/hr not_active Application Discontinuation
- 2004-06-07 AT AT04736241T patent/ATE398107T1/de not_active IP Right Cessation
- 2004-06-07 EA EA200501730A patent/EA009881B1/ru not_active IP Right Cessation
- 2004-06-07 EP EP04736241A patent/EP1638933B1/en not_active Expired - Lifetime
- 2004-06-07 PL PL04736241T patent/PL1638933T3/pl unknown
- 2004-06-07 AU AU2004247487A patent/AU2004247487B2/en not_active Expired - Fee Related
- 2004-06-07 AP AP2005003467A patent/AP2005003467A0/xx unknown
- 2004-06-07 WO PCT/IB2004/001943 patent/WO2004110995A1/en active IP Right Grant
- 2004-06-07 JP JP2006516540A patent/JP4137159B2/ja not_active Expired - Fee Related
- 2004-06-07 ES ES04736241T patent/ES2305776T3/es not_active Expired - Lifetime
- 2004-06-07 MX MXPA05013960A patent/MXPA05013960A/es active IP Right Grant
- 2004-06-07 NZ NZ544046A patent/NZ544046A/en unknown
- 2004-06-07 HR HR20080339T patent/HRP20080339T3/xx unknown
- 2004-06-07 BR BRPI0411594-5A patent/BRPI0411594A/pt not_active IP Right Cessation
- 2004-06-07 KR KR1020057024147A patent/KR100803796B1/ko not_active Expired - Fee Related
- 2004-06-07 PT PT04736241T patent/PT1638933E/pt unknown
- 2004-06-07 SI SI200430767T patent/SI1638933T1/sl unknown
- 2004-06-07 CA CA002530159A patent/CA2530159C/en not_active Expired - Fee Related
- 2004-06-07 DE DE602004014372T patent/DE602004014372D1/de not_active Expired - Lifetime
- 2004-06-14 UY UY28360A patent/UY28360A1/es not_active Application Discontinuation
- 2004-06-14 PE PE2004000590A patent/PE20050631A1/es not_active Application Discontinuation
- 2004-06-16 PA PA20048605301A patent/PA8605301A1/es unknown
- 2004-06-16 AR ARP040102082A patent/AR044715A1/es not_active Application Discontinuation
- 2004-06-16 TW TW093117317A patent/TW200505852A/zh unknown
- 2004-06-17 NL NL1026438A patent/NL1026438C2/nl not_active IP Right Cessation
- 2004-06-17 US US10/872,160 patent/US7378436B2/en not_active Expired - Fee Related
2005
- 2005-11-20 IL IL172063A patent/IL172063A0/en unknown
- 2005-11-21 IS IS8136A patent/IS8136A/is unknown
- 2005-12-16 EC EC2005006232A patent/ECSP056232A/es unknown
- 2005-12-16 MA MA28674A patent/MA27885A1/fr unknown
2008
- 2008-05-21 US US12/124,755 patent/US20080306123A1/en not_active Abandoned
- 2008-08-14 CY CY20081100869T patent/CY1110434T1/el unknown

Also Published As

Publication number	Publication date
KR20060036927A (ko)	2006-05-02
BRPI0411594A (pt)	2006-08-29
SI1638933T1 (sl)	2008-10-31
NL1026438A1 (nl)	2004-12-20
EP1638933B1 (en)	2008-06-11
ECSP056232A (es)	2006-04-19
IL172063A0 (en)	2009-02-11
MA27885A1 (fr)	2006-05-02
US7378436B2 (en)	2008-05-27
US20050137229A1 (en)	2005-06-23
NZ544046A (en)	2009-08-28
US20080306123A1 (en)	2008-12-11
AU2004247487B2 (en)	2010-05-20
PT1638933E (pt)	2008-07-22
AU2004247487A1 (en)	2004-12-23
WO2004110995A8 (en)	2005-04-21
WO2004110995A1 (en)	2004-12-23
MXPA05013960A (es)	2006-02-24
PA8605301A1 (es)	2005-02-04
EA009881B1 (ru)	2008-04-28
ATE398107T1 (de)	2008-07-15
EP1638933A1 (en)	2006-03-29
TW200505852A (en)	2005-02-16
CY1110434T1 (el)	2015-04-29
PL1638933T3 (pl)	2008-10-31
DE602004014372D1 (de)	2008-07-24
HRP20050993A2 (en)	2006-03-31
UY28360A1 (es)	2005-01-31
DK1638933T3 (da)	2008-07-28
AR044715A1 (es)	2005-09-21
CA2530159A1 (en)	2004-12-23
JP2006527758A (ja)	2006-12-07
EA200501730A1 (ru)	2006-08-25
KR100803796B1 (ko)	2008-02-14
JP4137159B2 (ja)	2008-08-20
NL1026438C2 (nl)	2005-09-20
PE20050631A1 (es)	2005-09-14
ES2305776T3 (es)	2008-11-01
AP2005003467A0 (en)	2006-12-31
CA2530159C (en)	2010-02-02
IS8136A (is)	2005-11-21

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