TR200402493T4 - Yeni 2,3-benzodiazepin türevleri ve aktif bileşen olarak bunları içeren farmasötik bileşimler. - Google Patents
Yeni 2,3-benzodiazepin türevleri ve aktif bileşen olarak bunları içeren farmasötik bileşimler.Info
- Publication number
- TR200402493T4 TR200402493T4 TR2004/02493T TR200402493T TR200402493T4 TR 200402493 T4 TR200402493 T4 TR 200402493T4 TR 2004/02493 T TR2004/02493 T TR 2004/02493T TR 200402493 T TR200402493 T TR 200402493T TR 200402493 T4 TR200402493 T4 TR 200402493T4
- Authority
- TR
- Turkey
- Prior art keywords
- group
- active ingredient
- pharmaceutical compositions
- compositions containing
- benzodiazepine derivatives
- Prior art date
Links
- RPBDCDQMCRHNLM-UHFFFAOYSA-N C1=NNC=C2C=CC=CC2=C1 Chemical class C1=NNC=C2C=CC=CC2=C1 RPBDCDQMCRHNLM-UHFFFAOYSA-N 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000002921 anti-spasmodic effect Effects 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- 230000000324 neuroprotective effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Bulus yeni formül I'e iliskin 2,3-benzodiazepin türevleri ve aktif bilesen olarak bunlari içeren farmasötik bilesimler ile ilgilidir. Yeni bilesikler antispazmodik, kas gevsetici ve sinir-koruyucu aktivitelere sahiptir. Formül I'de, X bir hidrojen atomunu, bir kloro atomunu veya bir metoksi grubunu temsil eder; Y bir hidrojen atomunu veya bir halo atomunu temsil eder; Z bir metil grubu veya bir kloro grubudur; R bir C1-4 alkil grubu veya -NR1R2 formülüne sahip bir gruptur; burada R1 ve R2 bagimsiz olarak bir hidrojen atomunu, bir C1-4 alkil grubunu, bir C1-4 alkoksi grubunu veya bir C3-6 sikloalkil grubunu temsil eder.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0004994A HU225100B1 (hu) | 2000-12-21 | 2000-12-21 | 2,3-Benzodiazepinszármazékok, ilyen hatóanyagot tartalmazó gyógyászati készítmények és alkalmazásuk |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200402493T4 true TR200402493T4 (tr) | 2004-12-21 |
Family
ID=89978876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2004/02493T TR200402493T4 (tr) | 2000-12-21 | 2001-12-19 | Yeni 2,3-benzodiazepin türevleri ve aktif bileşen olarak bunları içeren farmasötik bileşimler. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7189711B2 (tr) |
| EP (1) | EP1351942B1 (tr) |
| JP (1) | JP4201252B2 (tr) |
| AT (1) | ATE271548T1 (tr) |
| AU (1) | AU2002217356A1 (tr) |
| BG (1) | BG66199B1 (tr) |
| CA (1) | CA2431761C (tr) |
| CZ (1) | CZ301371B6 (tr) |
| DE (1) | DE60104448T2 (tr) |
| DK (1) | DK1351942T3 (tr) |
| EA (1) | EA005867B1 (tr) |
| ES (1) | ES2225412T3 (tr) |
| HU (1) | HU225100B1 (tr) |
| PL (1) | PL211495B1 (tr) |
| PT (1) | PT1351942E (tr) |
| RO (1) | RO121268B1 (tr) |
| SK (1) | SK286620B6 (tr) |
| TR (1) | TR200402493T4 (tr) |
| UA (1) | UA74615C2 (tr) |
| WO (1) | WO2002050044A1 (tr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0302449A3 (en) * | 2003-08-04 | 2005-06-28 | Egis Gyogyszergyar Nyilvanosan | 8-chloro-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for producing them |
| WO2007077469A1 (en) * | 2005-12-30 | 2007-07-12 | Egis Gyógyszergyár | Optical isomers of dihydro-2,3-benzodiazepines and their stereoselective synthesis |
| JP6333251B2 (ja) * | 2012-08-16 | 2018-05-30 | バイエル ファーマ アクチエンゲゼルシャフト | ２，３−ベンゾジアゼピン類 |
| JP2016521722A (ja) * | 2013-06-17 | 2016-07-25 | バイエル ファーマ アクチエンゲゼルシャフト | 置換フェニル−２，３−ベンゾジアゼピン |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU191698B (en) * | 1984-07-27 | 1987-03-30 | Gyogyszerkutato Intezet | Process for producing new 1-aryl-5h-2beta-benzodiazepines |
| HU219778B (hu) * | 1990-12-21 | 2001-07-30 | Gyógyszerkutató Intézet Közös Vállalat | Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények |
| DE19604920A1 (de) * | 1996-02-01 | 1997-08-07 | Schering Ag | Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel |
| US5891871A (en) * | 1996-03-21 | 1999-04-06 | Cocensys, Inc. | Substituted 2,3-benzodiazepin-4-ones and the use thereof |
| HU9600871D0 (en) * | 1996-04-04 | 1996-05-28 | Gyogyszerkutato Intezet | New 2,3-benzodiazepine derivatives |
| HU227128B1 (en) * | 1999-07-07 | 2010-07-28 | Egyt Gyogyszervegyeszeti Gyar | New 2,3-benzodiazepine derivatives |
| RU2325811C2 (ru) | 2006-06-28 | 2008-06-10 | Общество С Ограниченной Ответственностью "Фито-Маг" | Способ хранения плодоовощной и растениеводческой продукции |
-
2000
- 2000-12-21 HU HU0004994A patent/HU225100B1/hu not_active IP Right Cessation
-
2001
- 2001-12-19 WO PCT/HU2001/000151 patent/WO2002050044A1/en active IP Right Grant
- 2001-12-19 TR TR2004/02493T patent/TR200402493T4/tr unknown
- 2001-12-19 PT PT01271364T patent/PT1351942E/pt unknown
- 2001-12-19 CZ CZ20031680A patent/CZ301371B6/cs not_active IP Right Cessation
- 2001-12-19 CA CA2431761A patent/CA2431761C/en not_active Expired - Fee Related
- 2001-12-19 SK SK788-2003A patent/SK286620B6/sk not_active IP Right Cessation
- 2001-12-19 AT AT01271364T patent/ATE271548T1/de not_active IP Right Cessation
- 2001-12-19 EP EP01271364A patent/EP1351942B1/en not_active Expired - Lifetime
- 2001-12-19 DK DK01271364T patent/DK1351942T3/da active
- 2001-12-19 PL PL362029A patent/PL211495B1/pl unknown
- 2001-12-19 EA EA200300691A patent/EA005867B1/ru not_active IP Right Cessation
- 2001-12-19 AU AU2002217356A patent/AU2002217356A1/en not_active Abandoned
- 2001-12-19 US US10/450,898 patent/US7189711B2/en not_active Expired - Fee Related
- 2001-12-19 ES ES01271364T patent/ES2225412T3/es not_active Expired - Lifetime
- 2001-12-19 JP JP2002551541A patent/JP4201252B2/ja not_active Expired - Fee Related
- 2001-12-19 RO ROA200300539A patent/RO121268B1/ro unknown
- 2001-12-19 DE DE60104448T patent/DE60104448T2/de not_active Expired - Lifetime
- 2001-12-19 UA UA2003076874A patent/UA74615C2/uk unknown
-
2003
- 2003-06-20 BG BG107932A patent/BG66199B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA200300691A1 (ru) | 2003-12-25 |
| CZ20031680A3 (cs) | 2003-11-12 |
| WO2002050044A1 (en) | 2002-06-27 |
| US7189711B2 (en) | 2007-03-13 |
| AU2002217356A1 (en) | 2002-07-01 |
| BG66199B1 (bg) | 2012-01-31 |
| US20040092510A1 (en) | 2004-05-13 |
| JP4201252B2 (ja) | 2008-12-24 |
| CZ301371B6 (cs) | 2010-02-03 |
| JP2004516284A (ja) | 2004-06-03 |
| PL211495B1 (pl) | 2012-05-31 |
| DE60104448D1 (de) | 2004-08-26 |
| CA2431761C (en) | 2010-05-25 |
| SK286620B6 (sk) | 2009-02-05 |
| ATE271548T1 (de) | 2004-08-15 |
| BG107932A (bg) | 2004-02-27 |
| EP1351942A1 (en) | 2003-10-15 |
| ES2225412T3 (es) | 2005-03-16 |
| SK7882003A3 (en) | 2003-11-04 |
| PL362029A1 (en) | 2004-10-18 |
| PT1351942E (pt) | 2004-11-30 |
| HUP0004994A2 (hu) | 2002-11-28 |
| DE60104448T2 (de) | 2005-07-28 |
| HU225100B1 (hu) | 2006-06-28 |
| RO121268B1 (ro) | 2007-02-28 |
| EP1351942B1 (en) | 2004-07-21 |
| EA005867B1 (ru) | 2005-06-30 |
| CA2431761A1 (en) | 2002-06-27 |
| HU0004994D0 (en) | 2001-03-28 |
| DK1351942T3 (da) | 2004-11-22 |
| UA74615C2 (en) | 2006-01-16 |
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