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TR200202048T2 - Sitalopramin preparasyon metodu. - Google Patents

Sitalopramin preparasyon metodu.

Info

Publication number
TR200202048T2
TR200202048T2 TR2002/02048T TR200202048T TR200202048T2 TR 200202048 T2 TR200202048 T2 TR 200202048T2 TR 2002/02048 T TR2002/02048 T TR 2002/02048T TR 200202048 T TR200202048 T TR 200202048T TR 200202048 T2 TR200202048 T2 TR 200202048T2
Authority
TR
Turkey
Prior art keywords
preparation
citalopramine
formula
citalopram
alkylated
Prior art date
Application number
TR2002/02048T
Other languages
English (en)
Inventor
Petersen Hans
Harold Rock Michael
Original Assignee
H.Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159208&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200202048(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H.Lundbeck A/S filed Critical H.Lundbeck A/S
Publication of TR200202048T2 publication Critical patent/TR200202048T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Furan Compounds (AREA)

Abstract

Formül (II)' ye ait aldehitin, baz veya bunun asit ilaveli bir tuzu seklinde izole edilen sitalopram olusturmak üzere alkile edilen formül (I)' e ait ilgili 5-siyano bilesigine dönüstürüldügü sitalopram preparasyonuna yönelik bir metot.
TR2002/02048T 2000-02-24 2001-02-22 Sitalopramin preparasyon metodu. TR200202048T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200000296 2000-02-24

Publications (1)

Publication Number Publication Date
TR200202048T2 true TR200202048T2 (tr) 2003-01-21

Family

ID=8159208

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/02048T TR200202048T2 (tr) 2000-02-24 2001-02-22 Sitalopramin preparasyon metodu.

Country Status (29)

Country Link
US (3) US20020004604A1 (tr)
EP (1) EP1259500A1 (tr)
JP (1) JP2003524009A (tr)
KR (1) KR20020080438A (tr)
CN (1) CN1161350C (tr)
AU (1) AU2001235357A1 (tr)
BE (1) BE1012921A6 (tr)
BG (1) BG107015A (tr)
BR (1) BR0108947A (tr)
CA (1) CA2400682A1 (tr)
EA (1) EA005593B1 (tr)
FR (1) FR2805813A1 (tr)
GR (1) GR20010100097A (tr)
HK (1) HK1054378B (tr)
HR (1) HRP20020743A2 (tr)
HU (1) HUP0300078A3 (tr)
IE (1) IES20010143A2 (tr)
IL (1) IL151339A0 (tr)
IS (1) IS6512A (tr)
IT (1) ITMI20010385A1 (tr)
MX (1) MXPA02008230A (tr)
NL (1) NL1017414C1 (tr)
NO (1) NO20024007L (tr)
PL (1) PL357178A1 (tr)
SK (1) SK13662002A3 (tr)
TR (1) TR200202048T2 (tr)
UA (1) UA71059C2 (tr)
WO (1) WO2001062754A1 (tr)
ZA (2) ZA200206255B (tr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DE69907037T3 (de) 1999-04-14 2010-02-18 H. Lundbeck A/S Verfahren zur herstellung von citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
DK1228056T3 (da) 1999-10-25 2005-01-24 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
US6310222B1 (en) * 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
IL150335A0 (en) 1999-12-28 2002-12-01 Lundbeck & Co As H Method for the preparation of citalopram
CZ20022627A3 (cs) 1999-12-30 2002-10-16 H. Lundbeck A/S Způsob výroby citalopramu
DK1254129T3 (da) * 2000-01-14 2004-03-29 Lundbeck & Co As H Fremgangsmåde til fremstilling af 5-cyanophthalid
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
HUP0300274A2 (hu) 2000-03-13 2003-06-28 H. Lundbeck A/S Eljárás citalopram előállítására
IL151566A0 (en) 2000-03-13 2003-04-10 Lundbeck & Co As H Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
SK14512002A3 (sk) 2000-03-14 2003-03-04 H. Lundbeck A/S Spôsob výroby citalopramu, medziprodukt a citalopram výrobený týmto spôsobom
BR0109180A (pt) * 2000-03-16 2003-05-27 Lundbeck & Co As H Método para a preparação de 5-ciano-1-(4-fluorofenil) -1,3- diidroisobenzofuranos e composição farmacêutica de antidepressivo
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
FI20011622L (fi) 2000-08-18 2002-02-19 Lundbeck & Co As H Menetelmä sitalopraamin valmistamiseksi
TR200201166T1 (tr) 2000-12-22 2002-10-21 H.Lundbecks A/S Saf sitalopram hazırlanması için yöntem
DE60108105T2 (de) * 2001-08-02 2005-12-08 Infosint Sa Verfahren zur Herstellung von 5-substituierten Isobenzofuranen
WO2004016602A1 (en) * 2002-08-14 2004-02-26 Natco Pharma Limited Process for the preparation of high purity citalopram and its pharmaceutically acceptable salts
US8539533B2 (en) * 2003-03-07 2013-09-17 Siemens Enterprise Communications, Inc. System and method for digital personal video stream manager
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
JP2006176490A (ja) * 2004-11-29 2006-07-06 Sumitomo Chemical Co Ltd ５−フタランカルボニトリル及びシタロプラムの製造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
DE69907037T3 (de) * 1999-04-14 2010-02-18 H. Lundbeck A/S Verfahren zur herstellung von citalopram
US6310222B1 (en) * 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate

Also Published As

Publication number Publication date
EP1259500A1 (en) 2002-11-27
US20030083508A1 (en) 2003-05-01
IES20010143A2 (en) 2001-07-25
US20020004604A1 (en) 2002-01-10
EA005593B1 (ru) 2005-04-28
HUP0300078A3 (en) 2005-02-28
NO20024007L (no) 2002-10-07
BG107015A (bg) 2003-05-30
BR0108947A (pt) 2003-06-03
HRP20020743A2 (en) 2003-12-31
FR2805813A1 (fr) 2001-09-07
CN1404475A (zh) 2003-03-19
JP2003524009A (ja) 2003-08-12
HK1054378A1 (en) 2003-11-28
KR20020080438A (ko) 2002-10-23
HUP0300078A2 (en) 2003-05-28
ZA200206699B (en) 2003-11-21
UA71059C2 (uk) 2004-11-15
CN1161350C (zh) 2004-08-11
NO20024007D0 (no) 2002-08-22
NL1017414C1 (nl) 2001-03-15
IS6512A (is) 2002-08-20
ITMI20010385A1 (it) 2002-08-26
HK1054378B (zh) 2005-04-29
US20030114692A1 (en) 2003-06-19
WO2001062754A1 (en) 2001-08-30
MXPA02008230A (es) 2003-05-23
GR20010100097A (el) 2001-10-31
SK13662002A3 (sk) 2003-01-09
PL357178A1 (en) 2004-07-26
EA200200900A1 (ru) 2003-02-27
AU2001235357A1 (en) 2001-09-03
CA2400682A1 (en) 2001-08-30
IL151339A0 (en) 2003-04-10
BE1012921A6 (fr) 2001-05-08
ZA200206255B (en) 2003-10-20

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