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TR199501274A2 - Lipoksigenas enzimin islevine mani olucu 5-lipoksigenas inhibitörler. - Google Patents

Lipoksigenas enzimin islevine mani olucu 5-lipoksigenas inhibitörler.

Info

Publication number
TR199501274A2
TR199501274A2 TR95/01274A TR9501274A TR199501274A2 TR 199501274 A2 TR199501274 A2 TR 199501274A2 TR 95/01274 A TR95/01274 A TR 95/01274A TR 9501274 A TR9501274 A TR 9501274A TR 199501274 A2 TR199501274 A2 TR 199501274A2
Authority
TR
Turkey
Prior art keywords
alkyl
halo
cyano
alkylene
hydroxy
Prior art date
Application number
TR95/01274A
Other languages
English (en)
Inventor
Takashi Mano
Yoshiyuki Okumura
Rodney W Stevens
Kazunari Nakao
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of TR199501274A2 publication Critical patent/TR199501274A2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
TR95/01274A 1994-10-18 1995-10-18 Lipoksigenas enzimin islevine mani olucu 5-lipoksigenas inhibitörler. TR199501274A2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9401747 1994-10-18

Publications (1)

Publication Number Publication Date
TR199501274A2 true TR199501274A2 (tr) 1996-06-21

Family

ID=14098722

Family Applications (1)

Application Number Title Priority Date Filing Date
TR95/01274A TR199501274A2 (tr) 1994-10-18 1995-10-18 Lipoksigenas enzimin islevine mani olucu 5-lipoksigenas inhibitörler.

Country Status (31)

Country Link
EP (1) EP0787127B1 (tr)
JP (1) JP3032579B2 (tr)
CN (1) CN1093536C (tr)
AT (1) ATE198474T1 (tr)
AU (1) AU681520B2 (tr)
BG (1) BG61768B1 (tr)
CA (1) CA2202057C (tr)
CO (1) CO4480026A1 (tr)
CZ (1) CZ287350B6 (tr)
DE (1) DE69519804T2 (tr)
DK (1) DK0787127T3 (tr)
ES (1) ES2153033T3 (tr)
FI (1) FI971632A (tr)
GR (1) GR3035471T3 (tr)
HU (1) HU221543B (tr)
IL (1) IL115581A (tr)
LV (1) LV11468B (tr)
MY (1) MY114680A (tr)
NO (1) NO314629B1 (tr)
NZ (1) NZ285163A (tr)
PE (1) PE49196A1 (tr)
PL (1) PL180104B1 (tr)
RU (1) RU2136666C1 (tr)
SI (1) SI9500392A (tr)
SK (1) SK281577B6 (tr)
TR (1) TR199501274A2 (tr)
TW (1) TW411339B (tr)
UA (1) UA45312C2 (tr)
WO (1) WO1996011911A1 (tr)
YU (1) YU65995A (tr)
ZA (1) ZA958748B (tr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239285B1 (en) 1998-02-06 2001-05-29 Pfizer Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
US6194585B1 (en) * 1998-12-22 2001-02-27 Pfizer Inc. Process for preparing 5-lipoxygenase inhibitors
US6346624B1 (en) * 1999-08-31 2002-02-12 Pfizer Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
US6344563B1 (en) 1999-08-31 2002-02-05 Timothy Norris Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
SG87145A1 (en) * 1999-08-31 2002-03-19 Pfizer Prod Inc Process for making 5-lipoxygenase inhibitors having varied heterocyclic ring systems
AU2001245897B2 (en) * 2000-03-24 2006-07-06 Euro-Celtique S.A. Aryl substituted pyrazoles, triazoles and tetrazoles as sodium channel blocker
JP4365099B2 (ja) * 2001-04-20 2009-11-18 ノボザイムス アクティーゼルスカブ リポキシゲナーゼ
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
UA92833C2 (en) 2006-11-27 2010-12-10 Пфайзер Продактс Инк. Pyrazole analogues
AU2008331199A1 (en) * 2007-11-26 2009-06-04 Pfizer Inc. Pyrazole derivatives as 5-LO inhibitors
CA2866210A1 (en) * 2012-02-28 2013-09-06 Piramal Enterprises Limited Phenyl alkanoic acid derivatives as gpr agonists
PT3762368T (pt) 2018-03-08 2022-05-06 Incyte Corp Compostos de aminopirazina diol como inibidores de pi3k-y
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0462830B1 (en) * 1990-06-21 1995-10-18 Zeneca Limited Cyclic ether derivatives
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
EP0505122A1 (en) * 1991-03-21 1992-09-23 Zeneca Limited Alpha, alpha-dialkylbenzyl derivatives
EP0540165A1 (en) * 1991-10-03 1993-05-05 Zeneca Limited Alkanoic acid derivatives
DE69403795T2 (de) * 1993-06-14 1997-09-18 Pfizer Imidazole als lipoxygenase inhibitoren

Also Published As

Publication number Publication date
FI971632A0 (fi) 1997-04-17
UA45312C2 (uk) 2002-04-15
LV11468A (lv) 1996-08-20
PL319727A1 (en) 1997-08-18
CZ117797A3 (cs) 1998-06-17
AU681520B2 (en) 1997-08-28
CA2202057A1 (en) 1996-04-25
TW411339B (en) 2000-11-11
ES2153033T3 (es) 2001-02-16
ZA958748B (en) 1997-04-17
IL115581A (en) 1999-10-28
RU2136666C1 (ru) 1999-09-10
MY114680A (en) 2002-12-31
DE69519804D1 (de) 2001-02-08
NZ285163A (en) 1998-08-26
GR3035471T3 (en) 2001-05-31
SI9500392A (en) 1996-08-31
NO971773D0 (no) 1997-04-17
HU221543B (hu) 2002-11-28
JPH11507322A (ja) 1999-06-29
LV11468B (en) 1996-12-20
PL180104B1 (pl) 2000-12-29
NO971773L (no) 1997-06-17
JP3032579B2 (ja) 2000-04-17
EP0787127B1 (en) 2001-01-03
PE49196A1 (es) 1996-11-21
ATE198474T1 (de) 2001-01-15
SK128795A3 (en) 1996-07-03
DE69519804T2 (de) 2001-04-19
EP0787127A1 (en) 1997-08-06
SK281577B6 (sk) 2001-05-10
CO4480026A1 (es) 1997-07-09
CN1169722A (zh) 1998-01-07
CA2202057C (en) 2001-10-09
FI971632A (fi) 1997-04-17
CZ287350B6 (en) 2000-10-11
YU65995A (sh) 1999-06-15
IL115581A0 (en) 1996-01-19
BG100070A (bg) 1996-05-31
HUT77363A (hu) 1998-03-30
BG61768B1 (bg) 1998-05-29
WO1996011911A1 (en) 1996-04-25
CN1093536C (zh) 2002-10-30
DK0787127T3 (da) 2001-02-05
AU2417495A (en) 1996-05-06
NO314629B1 (no) 2003-04-22

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