SK8096A3 - 2,9-disubstituted purin-6-ones, manufacturing process thereof, pharmaceutical agent containing these subtances and their use - Google Patents

2,9-disubstituted purin-6-ones, manufacturing process thereof, pharmaceutical agent containing these subtances and their use Download PDF

Info

Publication number: SK8096A3
Authority: SK; Slovakia
Prior art keywords: carbon atoms; straight; branched alkyl; group; substituted
Prior art date: 1995-01-19

Application number

SK80-96A

Other languages

English (en)

Slovak (sk)

Inventor

Ulrich Niewohner

Erwin Bischoff

Helmuth Schutz

Elisabeth Perzborn

Matthias Schramm

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-01-19

Filing date

1996-01-18

Publication date

1996-08-07

1996-01-18 Application filed by Bayer Ag filed Critical Bayer Ag

1996-08-07 Publication of SK8096A3 publication Critical patent/SK8096A3/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Rheumatology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SK80-96A 1995-01-19 1996-01-18 2,9-disubstituted purin-6-ones, manufacturing process thereof, pharmaceutical agent containing these subtances and their use SK8096A3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19501482A DE19501482A1 (de)	1995-01-19	1995-01-19	2,9-disubstituierte Purin-6-one

Publications (1)

Publication Number	Publication Date
SK8096A3 true SK8096A3 (en)	1996-08-07

Family

ID=7751830

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK80-96A SK8096A3 (en)	1995-01-19	1996-01-18	2,9-disubstituted purin-6-ones, manufacturing process thereof, pharmaceutical agent containing these subtances and their use

Country Status (31)

Country	Link
US (1)	US5861404A (bg)
EP (1)	EP0722944A1 (bg)
JP (1)	JPH08231545A (bg)
KR (1)	KR960029334A (bg)
CN (1)	CN1135485A (bg)
AR (1)	AR002953A1 (bg)
AU (1)	AU4097996A (bg)
BG (1)	BG61728B1 (bg)
BR (1)	BR9600147A (bg)
CA (1)	CA2167353A1 (bg)
CO (1)	CO4700523A1 (bg)
CZ (1)	CZ16696A3 (bg)
DE (1)	DE19501482A1 (bg)
EE (1)	EE9600018A (bg)
FI (1)	FI960225L (bg)
HR (1)	HRP960007A2 (bg)
HU (1)	HUP9600106A3 (bg)
IL (1)	IL116769A (bg)
MA (1)	MA23778A1 (bg)
NO (1)	NO960223L (bg)
NZ (1)	NZ280830A (bg)
PE (1)	PE64996A1 (bg)
PL (1)	PL312354A1 (bg)
SG (1)	SG50401A1 (bg)
SK (1)	SK8096A3 (bg)
SV (1)	SV1996000006A (bg)
TN (2)	TNSN96007A1 (bg)
TR (1)	TR199600028A2 (bg)
TW (1)	TW314519B (bg)
YU (1)	YU1396A (bg)
ZA (1)	ZA96398B (bg)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19529102A1 (de) *	1995-08-08	1997-02-13	Kummer Horst Dieter	Verwendung von PDE-Inhibitoren bei der Behandlung von Harnblasenerkrankungen
US5824669A (en)	1996-03-22	1998-10-20	Nitromed, Inc.	Nitrosated and nitrosylated compounds and compositions and their use for treating respiratory disorders
USRE37234E1 (en)	1996-11-01	2001-06-19	Nitromed, Inc.	Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses
US5958926A (en)	1996-11-01	1999-09-28	Nitromed, Inc.	Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
KR20010021905A (ko) *	1997-07-15	2001-03-15	노미야마 아키히콰	신규인 푸린유도체 및 그 의약용도
CN1130363C (zh)	1997-11-12	2003-12-10	三菱化学株式会社	嘌呤衍生物以及含有其作为有效成分的药物
US6579868B1 (en) *	1998-01-05	2003-06-17	Eisai Co., Ltd.	Purine derivatives and adenosine A2 receptor antagonists serving as preventives/remedies for diabetes
US6124303A (en) *	1998-09-11	2000-09-26	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to 9-substituted 2-(2-N-aloxyphenyl) purin-6-ones
US6268372B1 (en)	1998-09-11	2001-07-31	Cell Pathways, Inc.	Method for inhibiting neoplastic cells and related conditions by exposure to 2,9-disubstituted purin-6-ones
JP3956188B2 (ja) *	1999-05-11	2007-08-08	三菱化学株式会社	プリン誘導体２水和物、それを有効成分として含む医薬およびその製造中間体
GB9924020D0 (en)	1999-10-11	1999-12-15	Pfizer Ltd	Pharmaceutically active compounds
MXPA03001958A (es) *	2000-09-06	2003-06-24	Tanabe Seiyaku Co	Preparaciones para administrar oral.
US7927623B2 (en) *	2001-02-15	2011-04-19	Mitsubishi Tanabe Pharma Corporation	Tablets quickly disintegrated in oral cavity
US6479493B1 (en)	2001-08-23	2002-11-12	Cell Pathways, Inc.	Methods for treatment of type I diabetes
US7276529B2 (en)	2002-03-20	2007-10-02	Celgene Corporation	Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US7893101B2 (en)	2002-03-20	2011-02-22	Celgene Corporation	Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US7208516B2 (en)	2002-03-20	2007-04-24	Celgene Corporation	Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US6962940B2 (en)	2002-03-20	2005-11-08	Celgene Corporation	(+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
CN102742513A (zh) *	2012-07-17	2012-10-24	南京熊猫机电制造有限公司	一种喂食栏装置
WO2015200177A1 (en)	2014-06-23	2015-12-30	Celgene Corporation	Apremilast for the treatment of a liver disease or a liver function abnormality
KR20210145787A (ko)	2019-04-02	2021-12-02	알리고스 테라퓨틱스 인코포레이티드	Prmt5를 표적으로 하는 화합물
JP7385467B2 (ja) *	2019-12-26	2023-11-22	キッセイ薬品工業株式会社	ヒポキサンチン化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4451478A (en) *	1982-03-12	1984-05-29	Newport Pharmaceuticals International, Inc.	Imidazole compounds
IL76546A (en) *	1984-10-12	1988-12-30	Warner Lambert Co	9-(heteroarylalkyl)-6-purine(thi)one derivatives,their preparation and pharmaceutical compositions containing them
GB9213623D0 (en) *	1992-06-26	1992-08-12	Pfizer Ltd	Therapeutic agents

1995
- 1995-01-19 DE DE19501482A patent/DE19501482A1/de not_active Withdrawn
- 1995-12-27 TW TW084113907A patent/TW314519B/zh active
1996
- 1996-01-08 HR HR19501482.0A patent/HRP960007A2/hr not_active Application Discontinuation
- 1996-01-08 EP EP96100156A patent/EP0722944A1/de not_active Withdrawn
- 1996-01-12 YU YU1396A patent/YU1396A/sh unknown
- 1996-01-12 US US08/587,321 patent/US5861404A/en not_active Expired - Fee Related
- 1996-01-15 TR TR96/00028A patent/TR199600028A2/xx unknown
- 1996-01-15 AU AU40979/96A patent/AU4097996A/en not_active Abandoned
- 1996-01-16 CA CA002167353A patent/CA2167353A1/en not_active Abandoned
- 1996-01-16 NZ NZ280830A patent/NZ280830A/en unknown
- 1996-01-16 IL IL11676996A patent/IL116769A/en not_active IP Right Cessation
- 1996-01-17 FI FI960225A patent/FI960225L/fi unknown
- 1996-01-17 TN TNTNSN96007A patent/TNSN96007A1/fr unknown
- 1996-01-17 PL PL96312354A patent/PL312354A1/xx unknown
- 1996-01-17 TN TNTNSN96006A patent/TNSN96006A1/fr unknown
- 1996-01-17 SG SG1996000260A patent/SG50401A1/en unknown
- 1996-01-18 JP JP8023473A patent/JPH08231545A/ja active Pending
- 1996-01-18 HU HU9600106A patent/HUP9600106A3/hu unknown
- 1996-01-18 EE EE9600018A patent/EE9600018A/xx unknown
- 1996-01-18 MA MA24133A patent/MA23778A1/fr unknown
- 1996-01-18 BR BR9600147A patent/BR9600147A/pt active Search and Examination
- 1996-01-18 BG BG100292A patent/BG61728B1/bg unknown
- 1996-01-18 ZA ZA96398A patent/ZA96398B/xx unknown
- 1996-01-18 NO NO960223A patent/NO960223L/no unknown
- 1996-01-18 CZ CZ96166A patent/CZ16696A3/cs unknown
- 1996-01-18 SK SK80-96A patent/SK8096A3/sk unknown
- 1996-01-18 KR KR1019960001002A patent/KR960029334A/ko not_active Application Discontinuation
- 1996-01-19 CO CO96002169A patent/CO4700523A1/es unknown
- 1996-01-19 AR ARP960101088A patent/AR002953A1/es unknown
- 1996-01-19 PE PE1996000043A patent/PE64996A1/es not_active Application Discontinuation
- 1996-01-19 SV SV1996000006A patent/SV1996000006A/es unknown
- 1996-01-19 CN CN96101917A patent/CN1135485A/zh active Pending

Also Published As

Publication number	Publication date
AR002953A1 (es)	1998-05-27
NO960223L (no)	1996-07-22
TW314519B (bg)	1997-09-01
CO4700523A1 (es)	1998-12-29
TNSN96006A1 (fr)	2005-03-15
HUP9600106A2 (en)	1997-05-28
NZ280830A (en)	1998-04-27
HUP9600106A3 (en)	1998-04-28
BG100292A (bg)	1996-07-31
NO960223D0 (no)	1996-01-18
HU9600106D0 (en)	1996-03-28
FI960225L (fi)	1996-07-20
MA23778A1 (fr)	1996-10-01
CZ16696A3 (en)	1996-08-14
PL312354A1 (en)	1996-07-22
PE64996A1 (es)	1997-03-09
CN1135485A (zh)	1996-11-13
TR199600028A2 (tr)	1996-08-21
BR9600147A (pt)	1998-01-06
EP0722944A1 (de)	1996-07-24
EE9600018A (et)	1996-08-15
CA2167353A1 (en)	1996-07-20
AU4097996A (en)	1996-07-25
HRP960007A2 (en)	1998-02-28
ZA96398B (en)	1996-08-28
IL116769A0 (en)	1996-05-14
US5861404A (en)	1999-01-19
KR960029334A (ko)	1996-08-17
DE19501482A1 (de)	1996-07-25
JPH08231545A (ja)	1996-09-10
YU1396A (sh)	1999-03-04
IL116769A (en)	1998-12-06
BG61728B1 (bg)	1998-04-30
TNSN96007A1 (fr)	2005-03-15
FI960225A0 (fi)	1996-01-17
SV1996000006A (es)	1996-10-29
SG50401A1 (en)	1998-07-20

Publication	Publication Date	Title
SK8096A3 (en)	1996-08-07	2,9-disubstituted purin-6-ones, manufacturing process thereof, pharmaceutical agent containing these subtances and their use
SK7796A3 (en)	1996-08-07	2,8-disubstituted quinazolines, their manufacturing process, pharmaceutical drug containing these substances and their application
US6794391B2 (en)	2004-09-21	Derivatives of pyrimido[6.1-a]isoquinolin-4-one
AU720305B2 (en)	2000-05-25	Purin-6-one derivatives
EP0370901B1 (fr)	1995-02-01	Nouveaux dérivés du chromanne actifs sur le système nerveux central, leur procédé de préparation et les compositions pharmaceutiques en contenant
SK7696A3 (en)	1996-08-07	9-substituted 2-(2-n-alkoxyphenyl)-purin-6-ones, manufacturing process thereof, pharmaceutical agent containing these subtances and their use
US5721267A (en)	1998-02-24	Chemotherapeutic pyrrolocarbazole derivatives
EP0586585B1 (en)	2000-07-05	1,2-dihydropyrido(3,4-b)pyrazines as fungicides
JPH01279865A (ja)	1989-11-10	新規の１，２―ジヒドロピリド〔３，４―ｂ〕―ピラジン類製造用の中間体
IE920120A1 (en)	1992-07-29	2,4-DIOXO-PYRIDO[2,3-d]PYRIMIDINE-3-ACETIC ACIDS AND ESTERS¹AND SALTS THEREOF
DE102004060752A1 (de)	2006-06-22	Hetaryloxy-substituierte Phenylaminopyrimidine