SK285639B6 - Modifikovaná ľudská TNFalfa molekula, DNA kódujúce takéto TNFalfa molekuly, spôsob výroby modifikovanej ľudskej TNFalfa molekuly, vakcíny obsahujúce modifikované TNFalfa molekuly a DNA a ich použitie - Google Patents

Modifikovaná ľudská TNFalfa molekula, DNA kódujúce takéto TNFalfa molekuly, spôsob výroby modifikovanej ľudskej TNFalfa molekuly, vakcíny obsahujúce modifikované TNFalfa molekuly a DNA a ich použitie Download PDF

Info

Publication number: SK285639B6
Authority: SK; Slovakia
Prior art keywords: tnfα; molecule; modified; modified human; human tnfα
Prior art date: 1997-04-15

Application number

SK1409-99A

Other languages

English (en)

Slovak (sk)

Other versions

SK140999A3 (en

Inventor

Martin Roland Jensen

Soren Mouritsen

Henrik Elsner

Iben Dalum

Original Assignee

Pharmexa A/S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-04-15

Filing date

1998-04-15

Publication date

2007-05-03

1998-04-15 Application filed by Pharmexa A/S filed Critical Pharmexa A/S

2000-06-12 Publication of SK140999A3 publication Critical patent/SK140999A3/sk

2007-05-03 Publication of SK285639B6 publication Critical patent/SK285639B6/sk

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/14—Lymphokine; related peptides
- Y10S930/144—Tumor necrosis factor

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Health & Medical Sciences (AREA)
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Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
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Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
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Biochemistry (AREA)
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Engineering & Computer Science (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
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Gastroenterology & Hepatology (AREA)
Diabetes (AREA)
Toxicology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Hematology (AREA)
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Neurosurgery (AREA)
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Obesity (AREA)
Biomedical Technology (AREA)
Emergency Medicine (AREA)
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Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

SK1409-99A 1997-04-15 1998-04-15 Modifikovaná ľudská TNFalfa molekula, DNA kódujúce takéto TNFalfa molekuly, spôsob výroby modifikovanej ľudskej TNFalfa molekuly, vakcíny obsahujúce modifikované TNFalfa molekuly a DNA a ich použitie SK285639B6 (sk)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DK41897		1997-04-15
US4418797P	1997-04-24	1997-04-24
PCT/DK1998/000157 WO1998046642A1 (en)	1997-04-15	1998-04-15	MODIFIED TNFα MOLECULES, DNA ENCODING SUCH MODIFIED TNFα MOLECULES AND VACCINES COMPRISING SUCH MODIFIED TNFα MOLECULES AND DNA

Publications (2)

Publication Number	Publication Date
SK140999A3 SK140999A3 (en)	2000-06-12
SK285639B6 true SK285639B6 (sk)	2007-05-03

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SK1409-99A SK285639B6 (sk)	1997-04-15	1998-04-15	Modifikovaná ľudská TNFalfa molekula, DNA kódujúce takéto TNFalfa molekuly, spôsob výroby modifikovanej ľudskej TNFalfa molekuly, vakcíny obsahujúce modifikované TNFalfa molekuly a DNA a ich použitie

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US (1)	US7118750B1 (es)
EP (1)	EP0975668B1 (es)
JP (1)	JP2001521386A (es)
KR (1)	KR100522289B1 (es)
CN (1)	CN1178955C (es)
AR (1)	AR012427A1 (es)
AT (1)	ATE326481T1 (es)
AU (1)	AU743400B2 (es)
BR (1)	BR9811462A (es)
CA (1)	CA2289476A1 (es)
CZ (1)	CZ9903657A3 (es)
DE (1)	DE69834556T2 (es)
DK (1)	DK0975668T3 (es)
EE (1)	EE9900461A (es)
ES (1)	ES2264569T3 (es)
HK (1)	HK1022918A1 (es)
HR (1)	HRP980203B1 (es)
HU (1)	HUP0001930A3 (es)
IL (1)	IL132281A0 (es)
NO (1)	NO995002L (es)
NZ (1)	NZ337955A (es)
PL (1)	PL194221B1 (es)
RU (1)	RU2241715C2 (es)
SI (1)	SI0975668T1 (es)
SK (1)	SK285639B6 (es)
TR (1)	TR199902562T2 (es)
TW (1)	TW510921B (es)
UA (1)	UA72440C2 (es)
WO (1)	WO1998046642A1 (es)
ZA (1)	ZA983148B (es)

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RU2013125147A (ru)	2010-12-08	2015-01-20	Неовакс	Сильно инактивированная иммуногенная вакцина, сохраняющая высокую иммуногенность, и способ ее изготовления
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AU634379B2 (en)	1991-04-29	1993-02-18	Csl Limited	Recombinant immunocastration vaccine
SE9102808L (sv) *	1991-09-26	1993-03-27	Lars T Hellman Inst F Immunolo	Vaccin, foer humant bruk, vars avsedda effekt aer att lindra symptomen eller foerhindra uppkomsten av ige-medierade allergiska reaktioner
CA2119089A1 (en) *	1993-03-29	1994-09-30	David Banner	Tumor necrosis factor muteins
DK96493D0 (da)	1993-08-26	1993-08-26	Mouritsen Og Elsner Aps	Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden

1998
- 1998-04-15 AT AT98916866T patent/ATE326481T1/de not_active IP Right Cessation
- 1998-04-15 CN CNB988042142A patent/CN1178955C/zh not_active Expired - Fee Related
- 1998-04-15 HR HR980203A patent/HRP980203B1/xx not_active IP Right Cessation
- 1998-04-15 HU HU0001930A patent/HUP0001930A3/hu unknown
- 1998-04-15 EP EP98916866A patent/EP0975668B1/en not_active Expired - Lifetime
- 1998-04-15 US US09/060,294 patent/US7118750B1/en not_active Expired - Fee Related
- 1998-04-15 DK DK98916866T patent/DK0975668T3/da active
- 1998-04-15 UA UA99116210A patent/UA72440C2/uk unknown
- 1998-04-15 DE DE69834556T patent/DE69834556T2/de not_active Expired - Fee Related
- 1998-04-15 CA CA002289476A patent/CA2289476A1/en not_active Abandoned
- 1998-04-15 JP JP54338798A patent/JP2001521386A/ja active Pending
- 1998-04-15 NZ NZ337955A patent/NZ337955A/xx unknown
- 1998-04-15 WO PCT/DK1998/000157 patent/WO1998046642A1/en not_active Application Discontinuation
- 1998-04-15 EE EEP199900461A patent/EE9900461A/xx unknown
- 1998-04-15 RU RU99122686/13A patent/RU2241715C2/ru not_active IP Right Cessation
- 1998-04-15 AU AU70303/98A patent/AU743400B2/en not_active Ceased
- 1998-04-15 ES ES98916866T patent/ES2264569T3/es not_active Expired - Lifetime
- 1998-04-15 IL IL13228198A patent/IL132281A0/xx unknown
- 1998-04-15 KR KR10-1999-7009504A patent/KR100522289B1/ko not_active IP Right Cessation
- 1998-04-15 SK SK1409-99A patent/SK285639B6/sk unknown
- 1998-04-15 SI SI9830845T patent/SI0975668T1/sl unknown
- 1998-04-15 PL PL98336295A patent/PL194221B1/pl not_active IP Right Cessation
- 1998-04-15 AR ARP980101722A patent/AR012427A1/es unknown
- 1998-04-15 BR BR9811462-0A patent/BR9811462A/pt not_active Application Discontinuation
- 1998-04-15 TR TR1999/02562T patent/TR199902562T2/xx unknown
- 1998-04-15 CZ CZ19993657A patent/CZ9903657A3/cs unknown
- 1998-04-15 ZA ZA9803148A patent/ZA983148B/xx unknown
- 1998-07-20 TW TW087111808A patent/TW510921B/zh not_active IP Right Cessation
1999
- 1999-10-14 NO NO995002A patent/NO995002L/no not_active Application Discontinuation
2000
- 2000-03-23 HK HK00101819A patent/HK1022918A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
TW510921B (en)	2002-11-21
CN1252809A (zh)	2000-05-10
DE69834556D1 (de)	2006-06-22
WO1998046642A1 (en)	1998-10-22
CZ9903657A3 (cs)	2001-09-12
EP0975668A1 (en)	2000-02-02
IL132281A0 (en)	2001-03-19
KR20010006416A (ko)	2001-01-26
NO995002D0 (no)	1999-10-14
ES2264569T3 (es)	2007-01-01
KR100522289B1 (ko)	2005-10-19
BR9811462A (pt)	2000-09-12
CA2289476A1 (en)	1998-10-22
JP2001521386A (ja)	2001-11-06
DE69834556T2 (de)	2007-05-10
NZ337955A (en)	2000-09-29
AR012427A1 (es)	2000-10-18
HRP980203A2 (en)	1998-12-31
NO995002L (no)	1999-12-15
HUP0001930A3 (en)	2001-10-29
PL194221B1 (pl)	2007-05-31
HK1022918A1 (en)	2000-08-25
PL336295A1 (en)	2000-06-19
EP0975668B1 (en)	2006-05-17
CN1178955C (zh)	2004-12-08
SK140999A3 (en)	2000-06-12
SI0975668T1 (sl)	2007-02-28
RU2241715C2 (ru)	2004-12-10
UA72440C2 (en)	2005-03-15
HRP980203B1 (en)	2003-04-30
TR199902562T2 (xx)	2000-02-21
ATE326481T1 (de)	2006-06-15
AU743400B2 (en)	2002-01-24
HUP0001930A2 (hu)	2000-09-28
ZA983148B (en)	1999-10-15
AU7030398A (en)	1998-11-11
US7118750B1 (en)	2006-10-10
DK0975668T3 (da)	2006-09-25
EE9900461A (et)	2000-06-15

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