SI2781525T1 - Derivati hemina s protibakterijskim in protivirusnim delovanjem - Google Patents
Derivati hemina s protibakterijskim in protivirusnim delovanjemInfo
- Publication number
- SI2781525T1 SI2781525T1 SI201231693T SI201231693T SI2781525T1 SI 2781525 T1 SI2781525 T1 SI 2781525T1 SI 201231693 T SI201231693 T SI 201231693T SI 201231693 T SI201231693 T SI 201231693T SI 2781525 T1 SI2781525 T1 SI 2781525T1
- Authority
- SI
- Slovenia
- Prior art keywords
- hemin
- antibacterial
- derivatives
- antiviral activity
- antiviral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
- C07F15/025—Iron compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
- C07K5/06069—Ser-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- C07K5/06095—Arg-amino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2011146831/04A RU2475498C1 (ru) | 2011-11-17 | 2011-11-17 | Новые производные гемина с антибактериальной и противовирусной активностью |
EP12850312.5A EP2781525B1 (en) | 2011-11-17 | 2012-11-15 | Derivatives of hemin with antibacterial and antiviral activity |
PCT/RU2012/000939 WO2013073998A2 (ru) | 2011-11-17 | 2012-11-15 | Новые производные гемина с антибактериальной и противовирусной активностью |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2781525T1 true SI2781525T1 (sl) | 2020-02-28 |
Family
ID=48430327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201231693T SI2781525T1 (sl) | 2011-11-17 | 2012-11-15 | Derivati hemina s protibakterijskim in protivirusnim delovanjem |
Country Status (14)
Country | Link |
---|---|
US (1) | US9605013B2 (sl) |
EP (1) | EP2781525B1 (sl) |
CN (1) | CN104039824B (sl) |
CY (1) | CY1122496T1 (sl) |
DK (1) | DK2781525T3 (sl) |
EA (1) | EA023667B1 (sl) |
ES (1) | ES2755937T3 (sl) |
HU (1) | HUE046503T2 (sl) |
PL (1) | PL2781525T3 (sl) |
PT (1) | PT2781525T (sl) |
RU (1) | RU2475498C1 (sl) |
SI (1) | SI2781525T1 (sl) |
UA (1) | UA116877C2 (sl) |
WO (1) | WO2013073998A2 (sl) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20160286801A1 (en) | 2013-03-15 | 2016-10-06 | Suncor Energy Inc. | Herbicidal Compositions |
RU2656595C1 (ru) * | 2018-03-16 | 2018-06-06 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Циклическое производное гемина с антимикробными свойствами и способ его синтеза |
CA3128733A1 (en) | 2019-02-15 | 2020-08-20 | Suncor Energy Inc. | The use of protoporphyrin ix derivatives to improve the health of plants |
CN111848656B (zh) * | 2020-06-24 | 2023-03-14 | 天津大学 | 离子修饰的原卟啉镓化合物及其制备方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05504774A (ja) | 1990-07-31 | 1993-07-22 | ザ ロックフェラー ユニバーシティ | エイズ治療を増進するためのメタロポルフィリン類の使用 |
RU2238950C2 (ru) * | 2002-04-25 | 2004-10-27 | Небольсин Владимир Евгеньевич | Производные гемина и их фармацевтически приемлемые соли, способ получения, применение и фармацевтическая композиция |
RU2250906C2 (ru) * | 2003-07-10 | 2005-04-27 | Небольсин Владимир Евгеньевич | Способы получения геминпептидов и их применение в качестве нуклеолитических агентов |
RU2296131C2 (ru) * | 2004-11-26 | 2007-03-27 | ООО "Фарминтерпрайсез" | Геминпептид, его фармацевтически приемлемые соли и применение в качестве противовирусного и вирулецидного агента |
RU2280649C1 (ru) * | 2004-11-26 | 2006-07-27 | ООО "Фарминтерпрайсез" | Геминпептиды, их фармацевтически приемлемые соли, фармкомпозиция и применение в качестве противоопухолевых агентов |
RU2404191C2 (ru) * | 2007-07-09 | 2010-11-20 | ООО "Фарминтерпрайсез" | Производные гемина или их фармацевтически приемлемые соли, способ получения, композиция и применение |
RU2415868C1 (ru) * | 2009-09-10 | 2011-04-10 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Производные гемина, обладающие антимикробной активностью, или их фармацевтически приемлемые соли, способ получения, фармкомпозиция и применение |
-
2011
- 2011-11-17 RU RU2011146831/04A patent/RU2475498C1/ru active
-
2012
- 2012-11-15 EP EP12850312.5A patent/EP2781525B1/en active Active
- 2012-11-15 US US14/358,998 patent/US9605013B2/en active Active
- 2012-11-15 DK DK12850312T patent/DK2781525T3/da active
- 2012-11-15 EA EA201490963A patent/EA023667B1/ru not_active IP Right Cessation
- 2012-11-15 WO PCT/RU2012/000939 patent/WO2013073998A2/ru active Application Filing
- 2012-11-15 CN CN201280062451.7A patent/CN104039824B/zh not_active Expired - Fee Related
- 2012-11-15 ES ES12850312T patent/ES2755937T3/es active Active
- 2012-11-15 SI SI201231693T patent/SI2781525T1/sl unknown
- 2012-11-15 HU HUE12850312A patent/HUE046503T2/hu unknown
- 2012-11-15 UA UAA201406790A patent/UA116877C2/uk unknown
- 2012-11-15 PT PT128503125T patent/PT2781525T/pt unknown
- 2012-11-15 PL PL12850312T patent/PL2781525T3/pl unknown
-
2019
- 2019-11-11 CY CY20191101177T patent/CY1122496T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP2781525A4 (en) | 2015-05-27 |
PT2781525T (pt) | 2019-12-05 |
WO2013073998A2 (ru) | 2013-05-23 |
WO2013073998A3 (ru) | 2013-08-08 |
CN104039824B (zh) | 2017-06-06 |
PL2781525T3 (pl) | 2020-05-18 |
CY1122496T1 (el) | 2021-01-27 |
EP2781525B1 (en) | 2019-10-16 |
ES2755937T3 (es) | 2020-04-24 |
CN104039824A (zh) | 2014-09-10 |
US9605013B2 (en) | 2017-03-28 |
US20150031854A1 (en) | 2015-01-29 |
EA023667B1 (ru) | 2016-06-30 |
RU2475498C1 (ru) | 2013-02-20 |
EA201490963A1 (ru) | 2014-12-30 |
DK2781525T3 (da) | 2019-11-18 |
UA116877C2 (uk) | 2018-05-25 |
HUE046503T2 (hu) | 2020-03-30 |
EP2781525A2 (en) | 2014-09-24 |
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