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SI2464645T1 - Zlite heterociklične spojine kot ionsko kanalni modulatorji - Google Patents

Zlite heterociklične spojine kot ionsko kanalni modulatorji

Info

Publication number
SI2464645T1
SI2464645T1 SI201031540T SI201031540T SI2464645T1 SI 2464645 T1 SI2464645 T1 SI 2464645T1 SI 201031540 T SI201031540 T SI 201031540T SI 201031540 T SI201031540 T SI 201031540T SI 2464645 T1 SI2464645 T1 SI 2464645T1
Authority
SI
Slovenia
Prior art keywords
ion channel
heterocyclic compounds
fused heterocyclic
channel modulators
modulators
Prior art date
Application number
SI201031540T
Other languages
English (en)
Inventor
Britton Corkey
Elfatih Elzein
Robert Jiang
Rao Kalla
Tetsuya Kobayashi
Dmitry Koltun
Xiaofen Li
Gregory Notte
Eric Parkhill
Thao Perry
Jeff Zablocki
Original Assignee
Gilead Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences, Inc. filed Critical Gilead Sciences, Inc.
Publication of SI2464645T1 publication Critical patent/SI2464645T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Pyridine Compounds (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
SI201031540T 2009-07-27 2010-07-26 Zlite heterociklične spojine kot ionsko kanalni modulatorji SI2464645T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US22886409P 2009-07-27 2009-07-27
US36003710P 2010-06-30 2010-06-30
PCT/US2010/043264 WO2011014462A1 (en) 2009-07-27 2010-07-26 Fused heterocyclic compounds as ion channel modulators
EP10737724.4A EP2464645B1 (en) 2009-07-27 2010-07-26 Fused heterocyclic compounds as ion channel modulators

Publications (1)

Publication Number Publication Date
SI2464645T1 true SI2464645T1 (sl) 2017-10-30

Family

ID=42751632

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201031540T SI2464645T1 (sl) 2009-07-27 2010-07-26 Zlite heterociklične spojine kot ionsko kanalni modulatorji

Country Status (23)

Country Link
US (2) US8952034B2 (sl)
EP (1) EP2464645B1 (sl)
CN (1) CN102725290B (sl)
AR (1) AR077598A1 (sl)
AU (1) AU2010276537B2 (sl)
CA (1) CA2774715C (sl)
CY (1) CY1119584T1 (sl)
DK (1) DK2464645T3 (sl)
EA (1) EA025824B1 (sl)
ES (1) ES2642586T3 (sl)
HR (1) HRP20171454T8 (sl)
HU (1) HUE034911T2 (sl)
LT (1) LT2464645T (sl)
ME (1) ME02847B (sl)
NZ (1) NZ598942A (sl)
PL (1) PL2464645T3 (sl)
PT (1) PT2464645T (sl)
RS (1) RS56410B1 (sl)
SI (1) SI2464645T1 (sl)
SM (1) SMT201700456T1 (sl)
TW (2) TWI542587B (sl)
UY (1) UY32805A (sl)
WO (1) WO2011014462A1 (sl)

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