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SI1633340T1 - Spojine za zdravljenje metaboličnih motenj - Google Patents

Spojine za zdravljenje metaboličnih motenj

Info

Publication number
SI1633340T1
SI1633340T1 SI200431588T SI200431588T SI1633340T1 SI 1633340 T1 SI1633340 T1 SI 1633340T1 SI 200431588 T SI200431588 T SI 200431588T SI 200431588 T SI200431588 T SI 200431588T SI 1633340 T1 SI1633340 T1 SI 1633340T1
Authority
SI
Slovenia
Prior art keywords
carbon atoms
ring
alkyl
hydrogen
treatment
Prior art date
Application number
SI200431588T
Other languages
English (en)
Inventor
Kirvin L Hodge
Shalini Sharma
Borstel Reid W Von
Stephen D Wolpe
Original Assignee
Wellstat Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Therapeutics Corp filed Critical Wellstat Therapeutics Corp
Publication of SI1633340T1 publication Critical patent/SI1633340T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200431588T 2003-04-15 2004-04-08 Spojine za zdravljenje metaboličnih motenj SI1633340T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46296003P 2003-04-15 2003-04-15
PCT/US2004/010799 WO2004091486A2 (en) 2003-04-15 2004-04-08 Compounds for the treatment of metabolic disorders
EP04759257A EP1633340B1 (en) 2003-04-15 2004-04-08 Compounds for the treatment of metabolic disorders

Publications (1)

Publication Number Publication Date
SI1633340T1 true SI1633340T1 (sl) 2011-02-28

Family

ID=33300020

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200431588T SI1633340T1 (sl) 2003-04-15 2004-04-08 Spojine za zdravljenje metaboličnih motenj

Country Status (25)

Country Link
US (2) US7514555B2 (sl)
EP (1) EP1633340B1 (sl)
JP (2) JP4766693B2 (sl)
KR (1) KR101127390B1 (sl)
CN (2) CN1774244A (sl)
AT (1) ATE487474T1 (sl)
AU (1) AU2004229418B2 (sl)
BR (1) BRPI0409469B1 (sl)
CA (1) CA2521621C (sl)
CY (1) CY1111310T1 (sl)
DE (1) DE602004030004D1 (sl)
DK (1) DK1633340T3 (sl)
ES (1) ES2353601T3 (sl)
HK (1) HK1084026A1 (sl)
IL (1) IL171269A (sl)
MX (1) MXPA05011042A (sl)
NO (1) NO20054791L (sl)
NZ (1) NZ542739A (sl)
PL (1) PL1633340T3 (sl)
PT (1) PT1633340E (sl)
RU (1) RU2358722C2 (sl)
SI (1) SI1633340T1 (sl)
UA (1) UA80195C2 (sl)
WO (1) WO2004091486A2 (sl)
ZA (1) ZA200507704B (sl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002100341A2 (en) * 2001-06-12 2002-12-19 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
JP2006507303A (ja) * 2002-11-01 2006-03-02 ウェルスタット セラピューティクス コーポレイション 代謝障害の処置のための化合物
CA2513092C (en) 2003-02-13 2011-11-01 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
SI1633340T1 (sl) * 2003-04-15 2011-02-28 Wellstat Therapeutics Corp Spojine za zdravljenje metaboličnih motenj
DE602004024382D1 (de) 2003-04-22 2010-01-14 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselstörungen
CN100348186C (zh) * 2003-04-30 2007-11-14 维尔斯达医疗公司 用于治疗代谢紊乱的化合物
EP1656127B1 (en) * 2003-08-20 2011-03-23 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
EP1868595B1 (en) * 2005-04-01 2012-01-11 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
UA95613C2 (ru) 2005-11-09 2011-08-25 Уеллстат Терепьютикс Корпорейшн Соединения для лечения расстройсв метаболизма
EP1976377A4 (en) * 2006-01-25 2010-06-23 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
US7947735B2 (en) * 2006-01-25 2011-05-24 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
CA2637373A1 (en) 2006-01-25 2007-08-02 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
US20090176885A1 (en) * 2006-02-02 2009-07-09 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
JP2009531288A (ja) * 2006-02-13 2009-09-03 ウェルスタット セラピューティクス コーポレイション 代謝障害の処置のための化合物
US20100227901A1 (en) * 2006-02-28 2010-09-09 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
JP2009532372A (ja) * 2006-03-31 2009-09-10 ウェルスタット セラピューティクス コーポレイション 代謝障害の併用治療
NZ572681A (en) * 2006-05-18 2012-01-12 Wellstat Therapeutics Corp Aromatic acetal carboxylic acid derivatives for the treatment of metabolic disorders
NZ573031A (en) * 2006-06-09 2011-11-25 Wellstat Therapeutics Corp Compounds for the treatment of metabolic disorders
CN101505594A (zh) * 2006-08-17 2009-08-12 维尔斯达医疗公司 代谢紊乱的组合治疗
JP5496913B2 (ja) * 2008-01-15 2014-05-21 ウェルスタット セラピューティクス コーポレイション 代謝異常の治療のための化合物
UA109638C2 (uk) 2008-03-13 2015-09-25 Сполуки та спосіб зниження рівня сечової кислоти
US8664433B2 (en) * 2008-05-05 2014-03-04 Wellstat Therapeutics Corporation Synthesis of 4-[3-(2,6-dimethylbenzyloxy)phenyl]-4-oxobutanoic acid
WO2010053910A1 (en) 2008-11-04 2010-05-14 Wellstat Therapeutics Corporation Synthesis of (phenylalkyloxy)phenyl-oxobutanoic acids
JP6458784B2 (ja) * 2016-08-03 2019-01-30 横河電機株式会社 駆動回路および電磁流量計

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WO2002100341A2 (en) * 2001-06-12 2002-12-19 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
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JP2006507303A (ja) * 2002-11-01 2006-03-02 ウェルスタット セラピューティクス コーポレイション 代謝障害の処置のための化合物
CA2513092C (en) * 2003-02-13 2011-11-01 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
SI1633340T1 (sl) * 2003-04-15 2011-02-28 Wellstat Therapeutics Corp Spojine za zdravljenje metaboličnih motenj
DE602004024382D1 (de) * 2003-04-22 2010-01-14 Wellstat Therapeutics Corp Verbindungen zur behandlung von stoffwechselstörungen
CN100348186C (zh) * 2003-04-30 2007-11-14 维尔斯达医疗公司 用于治疗代谢紊乱的化合物
EP1656127B1 (en) * 2003-08-20 2011-03-23 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
US7163470B2 (en) 2004-06-25 2007-01-16 Callaway Golf Company Golf club head
EP1868595B1 (en) 2005-04-01 2012-01-11 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
EP1976377A4 (en) * 2006-01-25 2010-06-23 Wellstat Therapeutics Corp COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
US7947735B2 (en) * 2006-01-25 2011-05-24 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders

Also Published As

Publication number Publication date
ZA200507704B (en) 2007-02-28
AU2004229418B2 (en) 2008-07-31
WO2004091486A2 (en) 2004-10-28
HK1084026A1 (en) 2006-07-21
PL1633340T3 (pl) 2011-04-29
AU2004229418A1 (en) 2004-10-28
JP2006523696A (ja) 2006-10-19
KR20050121262A (ko) 2005-12-26
MXPA05011042A (es) 2005-12-15
US20090156681A1 (en) 2009-06-18
NO20054791D0 (no) 2005-10-18
DE602004030004D1 (de) 2010-12-23
CA2521621C (en) 2011-11-01
WO2004091486A3 (en) 2005-01-20
CN1774244A (zh) 2006-05-17
ES2353601T3 (es) 2011-03-03
EP1633340A2 (en) 2006-03-15
IL171269A (en) 2011-09-27
RU2358722C2 (ru) 2009-06-20
KR101127390B1 (ko) 2012-03-23
NZ542739A (en) 2007-02-23
PT1633340E (pt) 2011-02-22
JP2011178808A (ja) 2011-09-15
EP1633340A4 (en) 2009-05-27
NO20054791L (no) 2005-12-20
UA80195C2 (en) 2007-08-27
EP1633340B1 (en) 2010-11-10
US7973052B2 (en) 2011-07-05
RU2005135441A (ru) 2006-03-20
CN101912380A (zh) 2010-12-15
JP5371062B2 (ja) 2013-12-18
BRPI0409469A (pt) 2006-04-18
DK1633340T3 (da) 2011-02-07
US20060014784A1 (en) 2006-01-19
CA2521621A1 (en) 2004-10-28
JP4766693B2 (ja) 2011-09-07
ATE487474T1 (de) 2010-11-15
US7514555B2 (en) 2009-04-07
BRPI0409469B1 (pt) 2016-04-26
CY1111310T1 (el) 2015-08-05

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