SI1371659T1 - Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli - Google Patents
Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soliInfo
- Publication number
- SI1371659T1 SI1371659T1 SI200330103T SI200330103T SI1371659T1 SI 1371659 T1 SI1371659 T1 SI 1371659T1 SI 200330103 T SI200330103 T SI 200330103T SI 200330103 T SI200330103 T SI 200330103T SI 1371659 T1 SI1371659 T1 SI 1371659T1
- Authority
- SI
- Slovenia
- Prior art keywords
- perindopril
- synthesis
- pharmaceutically acceptable
- acceptable salts
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03292133A EP1371659B1 (fr) | 2003-08-29 | 2003-08-29 | Nouveau procédé de synthèse du perindopril et de ses sels pharmaceutiquement acceptables |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1371659T1 true SI1371659T1 (sl) | 2006-02-28 |
Family
ID=29558494
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200330103T SI1371659T1 (sl) | 2003-08-29 | 2003-08-29 | Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7223872B2 (fr) |
| EP (1) | EP1371659B1 (fr) |
| JP (1) | JP4331207B2 (fr) |
| CN (1) | CN100374459C (fr) |
| AR (1) | AR045517A1 (fr) |
| AT (1) | ATE306496T1 (fr) |
| AU (1) | AU2004270429B2 (fr) |
| DE (1) | DE60301820T2 (fr) |
| DK (1) | DK1371659T3 (fr) |
| EA (1) | EA008626B1 (fr) |
| ES (1) | ES2250853T3 (fr) |
| HK (1) | HK1097852A1 (fr) |
| MY (1) | MY136288A (fr) |
| NZ (1) | NZ545338A (fr) |
| PL (1) | PL211507B1 (fr) |
| SI (1) | SI1371659T1 (fr) |
| WO (1) | WO2005023843A1 (fr) |
| ZA (1) | ZA200601426B (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60308102T2 (de) * | 2003-08-29 | 2007-06-21 | Les Laboratoires Servier | Verfahren für die Synthese von Perindopril und seiner pharmazeutisch annehmbaren Salzen |
| DE60302287T2 (de) * | 2003-08-29 | 2006-08-10 | Les Laboratoires Servier | Verfahren für die Synthese von Perindopril und seiner pharmazeutisch annehmbaren Salzen |
| WO2005037788A1 (fr) * | 2003-10-21 | 2005-04-28 | Lupin Ltd. | Nouvelle methode de preparation de perindopril erbumine cristalline |
| SI21704A (en) * | 2004-01-14 | 2005-08-31 | Lek Farmacevtska Druzba Dd | New crystal form of perindopril, procedure of its preparation, pharmaceutical preparations containing this form and their application in treatment of hypertensia |
| DE602005009918D1 (de) | 2005-01-06 | 2008-11-06 | Ipca Lab Ltd | Verfahren zur Synthese von (2S,3aS,7aS)-1-(S)-Alanyl-octahydro-1H-2-carbonsäurederivaten und Verwendung in der Synthese von Perindopril |
| WO2016178591A2 (fr) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Marqueurs génétiques et traitement de l'obésité masculine |
| PH12018502155B1 (en) | 2016-04-20 | 2024-03-27 | Servier Lab | Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid |
| CN113980096A (zh) * | 2021-11-29 | 2022-01-28 | 绍兴市上虞区武汉理工大学高等研究院 | 一种吨级培哚普利叔丁胺的合成工艺方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1319668T3 (da) * | 2003-03-12 | 2005-02-14 | Servier Lab | Fremgangsmåde til syntese af (2S, 3aS, 7aS)-1-((S)-alanyl)-octahydro-1H-indol-2-carboxylsyrederivater og anvendelse heraf ved syntese af perindopril |
| DE60302287T2 (de) * | 2003-08-29 | 2006-08-10 | Les Laboratoires Servier | Verfahren für die Synthese von Perindopril und seiner pharmazeutisch annehmbaren Salzen |
-
2003
- 2003-08-29 ES ES03292133T patent/ES2250853T3/es not_active Expired - Lifetime
- 2003-08-29 AT AT03292133T patent/ATE306496T1/de active
- 2003-08-29 EP EP03292133A patent/EP1371659B1/fr not_active Expired - Lifetime
- 2003-08-29 DE DE60301820T patent/DE60301820T2/de not_active Expired - Lifetime
- 2003-08-29 SI SI200330103T patent/SI1371659T1/sl unknown
- 2003-08-29 DK DK03292133T patent/DK1371659T3/da active
-
2004
- 2004-08-26 MY MYPI20043494A patent/MY136288A/en unknown
- 2004-08-27 AR ARP040103080A patent/AR045517A1/es not_active Application Discontinuation
- 2004-08-27 AU AU2004270429A patent/AU2004270429B2/en not_active Ceased
- 2004-08-27 ZA ZA200601426A patent/ZA200601426B/xx unknown
- 2004-08-27 WO PCT/FR2004/002198 patent/WO2005023843A1/fr active IP Right Grant
- 2004-08-27 CN CNB2004800235321A patent/CN100374459C/zh not_active Expired - Fee Related
- 2004-08-27 PL PL379627A patent/PL211507B1/pl unknown
- 2004-08-27 NZ NZ545338A patent/NZ545338A/en not_active IP Right Cessation
- 2004-08-27 JP JP2006524396A patent/JP4331207B2/ja not_active Expired - Fee Related
- 2004-08-27 US US10/570,565 patent/US7223872B2/en not_active Expired - Fee Related
- 2004-08-27 EA EA200600455A patent/EA008626B1/ru not_active IP Right Cessation
-
2007
- 2007-02-01 HK HK07101189A patent/HK1097852A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004270429B2 (en) | 2007-05-24 |
| PL379627A1 (pl) | 2006-10-30 |
| ES2250853T3 (es) | 2006-04-16 |
| DE60301820D1 (de) | 2006-02-23 |
| EP1371659A1 (fr) | 2003-12-17 |
| DK1371659T3 (da) | 2005-11-21 |
| JP4331207B2 (ja) | 2009-09-16 |
| WO2005023843A1 (fr) | 2005-03-17 |
| MY136288A (en) | 2008-09-30 |
| AU2004270429A1 (en) | 2005-03-17 |
| PL211507B1 (pl) | 2012-05-31 |
| EA008626B1 (ru) | 2007-06-29 |
| ZA200601426B (en) | 2007-05-30 |
| US20070088168A1 (en) | 2007-04-19 |
| CN1835965A (zh) | 2006-09-20 |
| JP2007536202A (ja) | 2007-12-13 |
| EP1371659B1 (fr) | 2005-10-12 |
| CN100374459C (zh) | 2008-03-12 |
| EA200600455A1 (ru) | 2006-08-25 |
| HK1097852A1 (en) | 2007-07-06 |
| NZ545338A (en) | 2009-03-31 |
| ATE306496T1 (de) | 2005-10-15 |
| DE60301820T2 (de) | 2006-07-13 |
| US7223872B2 (en) | 2007-05-29 |
| AR045517A1 (es) | 2005-11-02 |
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