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SG45439A1 - Separation of e nantiomers of cimaterol (-)-cimaterol and the use thereof as pharmaceutical composition or as performance enhancers - Google Patents

Separation of e nantiomers of cimaterol (-)-cimaterol and the use thereof as pharmaceutical composition or as performance enhancers

Info

Publication number
SG45439A1
SG45439A1 SG1996008586A SG1996008586A SG45439A1 SG 45439 A1 SG45439 A1 SG 45439A1 SG 1996008586 A SG1996008586 A SG 1996008586A SG 1996008586 A SG1996008586 A SG 1996008586A SG 45439 A1 SG45439 A1 SG 45439A1
Authority
SG
Singapore
Prior art keywords
cimaterol
nantiomers
separation
pharmaceutical composition
performance enhancers
Prior art date
Application number
SG1996008586A
Other languages
English (en)
Inventor
Wolfgang Resemann
Adolf Durr
Gunther Engelhardt
John Francis Quirke
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Publication of SG45439A1 publication Critical patent/SG45439A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Birds (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
SG1996008586A 1990-05-04 1991-04-26 Separation of e nantiomers of cimaterol (-)-cimaterol and the use thereof as pharmaceutical composition or as performance enhancers SG45439A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4014252A DE4014252A1 (de) 1990-05-04 1990-05-04 Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer

Publications (1)

Publication Number Publication Date
SG45439A1 true SG45439A1 (en) 1998-01-16

Family

ID=6405664

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996008586A SG45439A1 (en) 1990-05-04 1991-04-26 Separation of e nantiomers of cimaterol (-)-cimaterol and the use thereof as pharmaceutical composition or as performance enhancers

Country Status (27)

Country Link
US (4) US5248695A (cs)
EP (2) EP0589488B1 (cs)
JP (1) JP2944777B2 (cs)
KR (1) KR0183024B1 (cs)
AR (1) AR247728A1 (cs)
AT (2) ATE158277T1 (cs)
AU (1) AU645313B2 (cs)
BG (1) BG60743B1 (cs)
CA (1) CA2041818C (cs)
CZ (1) CZ286389B6 (cs)
DE (3) DE4014252A1 (cs)
DK (2) DK0455155T3 (cs)
ES (2) ES2075255T3 (cs)
FI (1) FI109600B (cs)
GR (2) GR3017064T3 (cs)
HU (1) HU214335B (cs)
ID (1) ID966B (cs)
IE (2) IE80651B1 (cs)
IL (1) IL98030A (cs)
NO (1) NO174803B (cs)
NZ (1) NZ238032A (cs)
PT (1) PT97544B (cs)
RU (1) RU2002737C1 (cs)
SG (1) SG45439A1 (cs)
SK (1) SK279258B6 (cs)
TW (1) TW197415B (cs)
ZA (1) ZA913337B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4014252A1 (de) * 1990-05-04 1991-11-07 Boehringer Ingelheim Vetmed Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer
GB2289842B (en) * 1991-04-05 1996-01-31 Sepracor Inc Improved use of ß2 bronchodilator drugs
GB9107196D0 (en) * 1991-04-05 1991-05-22 Sandoz Ag Improvements in or relating to organic compounds
WO1997026871A1 (en) * 1996-01-29 1997-07-31 Savor, Evelyn Method of treating undesired uterine contractions using optically pure r- or rr-isomers of adrenergic beta-2 agonists
US6110974A (en) 1997-04-30 2000-08-29 Bridge Pharma, Inc. Methods of accelerating muscle growth and improving feed efficiency in animals by using optically pure eutomers of adrenergic beta-2 receptor agonists, and food supplements containing the same
EP1787529A3 (en) * 1997-04-30 2009-11-18 Courage Corporation Pty Ltd. Composition and methods using an eutomer
ZA994264B (en) 1998-07-01 2000-01-25 Warner Lambert Co Stereoisomers with high affinity for adrenergic receptors.
US7232837B2 (en) 1999-06-29 2007-06-19 Mcneil-Ppc, Inc. Stereoisomers with high affinity for adrenergic receptors
CN1426401A (zh) * 2000-04-27 2003-06-25 贝林格尔英格海姆法玛公司 新的长效倍他米美类药物(betamimetics)其制备方法,及其作为药物组合物的用途
US20030162459A1 (en) * 2002-02-27 2003-08-28 Osbon Robert Lindsay Method for producing a nonwoven fabric with enhanced characteristics
US20040235922A1 (en) * 2003-05-15 2004-11-25 Baile Clifton A. Compositions and methods for inducing adipose tissue cell death
ES2297461T3 (es) 2003-09-09 2008-05-01 Fumapharm Ag Uso de derivados del acido fumarico para tratar la insuficiencia cardiaca y el asma.
SG124283A1 (en) * 2004-03-24 2006-08-30 Trusted Hub Ltd Document signature method & system
JP5021621B2 (ja) 2005-04-13 2012-09-12 アスション ファーマ エー／エス 皮膚の結合組織病を治療するためのβ−２アドレナリン受容体作動薬
WO2006128180A2 (en) * 2005-05-27 2006-11-30 Children's Medical Center Corporation Methods for the treatment of disease
WO2006138243A2 (en) * 2005-06-13 2006-12-28 University Of Vermont And State Agricultural College Inhibition of creatine uptake to promote weight loss
JP6039100B2 (ja) 2012-12-03 2016-12-07 ファイザー・インク 新規選択的アンドロゲン受容体モジュレーター

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL136601C (cs) * 1967-06-15
US4119710A (en) * 1972-12-18 1978-10-10 Boehringer Ingelheim Gmbh Bronchospasmolytic 1-(p-amino-phenyl)-2-amino-ethanols-(1) and salts
US4407819A (en) * 1980-08-25 1983-10-04 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for the depression of fat deposition in warm blooded animals
US4814350A (en) * 1986-09-10 1989-03-21 American Cyanamid Company Method of treating diabetes with 5-[1-hydroxy-2-(isopropylamino)ethyl]anthranilonitrile
US4792546A (en) * 1986-12-05 1988-12-20 American Cyanamid Company Method for increasing weight gains and reducing deposition of fat in animals
DE4014252A1 (de) * 1990-05-04 1991-11-07 Boehringer Ingelheim Vetmed Enantiomerentrennung von cimaterol, (-)-cimaterol und dessen verwendung als arzneimittel oder als leistungsfoerderer

Also Published As

Publication number Publication date
NO911746D0 (no) 1991-05-03
EP0589488A1 (de) 1994-03-30
IE80651B1 (en) 1998-11-04
AU7611191A (en) 1991-11-07
ATE158277T1 (de) 1997-10-15
IL98030A (en) 1995-12-31
EP0589488B1 (de) 1997-09-17
CA2041818C (en) 2003-02-11
US5648386A (en) 1997-07-15
DE4014252A1 (de) 1991-11-07
PT97544A (pt) 1992-01-31
NZ238032A (en) 1996-02-27
RU2002737C1 (ru) 1993-11-15
FI912151A (fi) 1991-11-05
DK0589488T3 (da) 1998-05-04
ID966B (id) 1996-09-30
CS129291A3 (en) 1991-11-12
US5395957A (en) 1995-03-07
BG94342A (en) 1994-06-30
CA2041818A1 (en) 1991-11-05
US5248695A (en) 1993-09-28
IL98030A0 (en) 1992-06-21
ES2075255T3 (es) 1995-10-01
JPH04225944A (ja) 1992-08-14
US5292753A (en) 1994-03-08
GR3025547T3 (en) 1998-03-31
DK0455155T3 (da) 1995-11-13
JP2944777B2 (ja) 1999-09-06
IE911507A1 (en) 1991-11-06
NO174803C (cs) 1994-07-13
GR3017064T3 (en) 1995-11-30
NO911746L (no) 1991-11-05
AU645313B2 (en) 1994-01-13
KR0183024B1 (ko) 1999-05-15
ATE124932T1 (de) 1995-07-15
CZ286389B6 (cs) 2000-03-15
TW197415B (cs) 1993-01-01
BG60743B1 (bg) 1996-02-29
EP0455155B1 (de) 1995-07-12
DE59105957D1 (de) 1995-08-17
HUT60999A (en) 1992-11-30
ZA913337B (en) 1993-01-27
PT97544B (pt) 1998-08-31
SK279258B6 (sk) 1998-08-05
FI109600B (fi) 2002-09-13
FI912151A0 (fi) 1991-05-03
EP0455155A1 (de) 1991-11-06
DE59108853D1 (de) 1997-10-23
HU214335B (hu) 1998-03-02
IE69017B1 (en) 1996-07-24
NO174803B (no) 1994-04-05
KR910019966A (ko) 1991-12-19
ES2109412T3 (es) 1998-01-16
HU911502D0 (en) 1991-11-28
AR247728A1 (es) 1995-03-31

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