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SG10201913015XA - Orthogonal cas9 proteins for rna-guided gene regulation and editing - Google Patents

Orthogonal cas9 proteins for rna-guided gene regulation and editing

Info

Publication number
SG10201913015XA
SG10201913015XA SG10201913015XA SG10201913015XA SG10201913015XA SG 10201913015X A SG10201913015X A SG 10201913015XA SG 10201913015X A SG10201913015X A SG 10201913015XA SG 10201913015X A SG10201913015X A SG 10201913015XA SG 10201913015X A SG10201913015X A SG 10201913015XA
Authority
SG
Singapore
Prior art keywords
editing
rna
gene regulation
cas9 proteins
guided gene
Prior art date
Application number
SG10201913015XA
Inventor
George M Church
Kevin Esvelt
Prashant Mali
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of SG10201913015XA publication Critical patent/SG10201913015XA/en

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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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SG10201913015XA 2013-07-10 2014-07-08 Orthogonal cas9 proteins for rna-guided gene regulation and editing SG10201913015XA (en)

Applications Claiming Priority (1)

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US201361844844P 2013-07-10 2013-07-10

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SG10201913015XA true SG10201913015XA (en) 2020-02-27

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SG10201800213VA SG10201800213VA (en) 2013-07-10 2014-07-08 Orthogonal cas9 proteins for rna-guided gene regulation and editing
SG10201913015XA SG10201913015XA (en) 2013-07-10 2014-07-08 Orthogonal cas9 proteins for rna-guided gene regulation and editing
SG11201600060VA SG11201600060VA (en) 2013-07-10 2014-07-08 Orthogonal cas9 proteins for rna-guided gene regulation and editing

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US (4) US10329587B2 (en)
EP (2) EP3019204B1 (en)
JP (3) JP6718813B2 (en)
KR (2) KR102285485B1 (en)
CN (2) CN110819658B (en)
AU (4) AU2014287397B2 (en)
BR (1) BR112016000571B1 (en)
CA (2) CA2917639C (en)
IL (3) IL282489B (en)
RU (3) RU2748433C2 (en)
SG (3) SG10201800213VA (en)
WO (1) WO2015006294A2 (en)

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