SE311646B - - Google Patents
Info
- Publication number
- SE311646B SE311646B SE8158/66A SE815866A SE311646B SE 311646 B SE311646 B SE 311646B SE 8158/66 A SE8158/66 A SE 8158/66A SE 815866 A SE815866 A SE 815866A SE 311646 B SE311646 B SE 311646B
- Authority
- SE
- Sweden
- Prior art keywords
- group
- acid
- nitro
- prepared
- alkyl
- Prior art date
Links
- 238000006243 chemical reaction Methods 0.000 abstract 4
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002947 alkylene group Chemical group 0.000 abstract 3
- 150000001412 amines Chemical class 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 150000008064 anhydrides Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 1
- HROLNPSYNSBBFH-UHFFFAOYSA-N 2-amino-5-(dimethylsulfamoyl)benzoic acid Chemical compound CN(C)S(=O)(=O)C1=CC=C(N)C(C(O)=O)=C1 HROLNPSYNSBBFH-UHFFFAOYSA-N 0.000 abstract 1
- GSINPMWETVUGBB-UHFFFAOYSA-N 5-chlorosulfonyl-2-nitrobenzoic acid Chemical compound OC(=O)C1=CC(S(Cl)(=O)=O)=CC=C1[N+]([O-])=O GSINPMWETVUGBB-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- BUBRXMAMXBDOCS-UHFFFAOYSA-N n,n-dimethyl-2,4-dioxo-1h-3,1-benzoxazine-6-sulfonamide Chemical compound N1C(=O)OC(=O)C2=CC(S(=O)(=O)N(C)C)=CC=C21 BUBRXMAMXBDOCS-UHFFFAOYSA-N 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH702763A CH439319A (de) | 1963-06-05 | 1963-06-05 | Verfahren zur Herstellung von N,N-aliphatisch disubstituierten 5-Dialkylsulfamyl-anthranil-säureamiden |
| CH419664 | 1964-04-02 | ||
| CH590064 | 1964-05-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE311646B true SE311646B (xx) | 1969-06-23 |
Family
ID=27174751
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE6822/64A SE311644B (xx) | 1963-06-05 | 1964-06-04 | |
| SE8159/66A SE311517B (xx) | 1963-06-05 | 1964-06-04 | |
| SE8158/66A SE311646B (xx) | 1963-06-05 | 1966-06-15 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE6822/64A SE311644B (xx) | 1963-06-05 | 1964-06-04 | |
| SE8159/66A SE311517B (xx) | 1963-06-05 | 1964-06-04 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3318882A (xx) |
| AT (3) | AT261593B (xx) |
| BE (1) | BE648829A (xx) |
| BR (1) | BR6459789D0 (xx) |
| DE (1) | DE1445629B1 (xx) |
| ES (1) | ES300569A1 (xx) |
| FR (3) | FR1403935A (xx) |
| GB (1) | GB1033268A (xx) |
| MY (1) | MY6900400A (xx) |
| NL (1) | NL140236B (xx) |
| SE (3) | SE311644B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL104059C (xx) * | 1955-05-03 | |||
| US3624202A (en) * | 1969-01-22 | 1971-11-30 | Roland Jaques | Process for stilling pain |
| US3678052A (en) * | 1970-06-11 | 1972-07-18 | Squibb & Sons Inc | Benzamide derivatives |
| CH590261A5 (xx) * | 1973-07-10 | 1977-07-29 | Ciba Geigy Ag | |
| DE2611705A1 (de) * | 1976-03-18 | 1977-09-22 | Josef Dipl Chem Dr Rer N Klosa | N-5-(nitrofurfuryliden-)-1-amino- hydantoin enthaltende kristalloesungsmittel |
| CH627446A5 (fr) * | 1978-01-17 | 1982-01-15 | Debiopharm Sa | Nouveaux derives de la benzamide. |
| EP0008072B1 (de) * | 1978-08-10 | 1984-02-22 | Ciba-Geigy Ag | Substituierte Anthranilsäureamide, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate und ihre Herstellung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB882090A (en) * | 1958-03-04 | 1961-11-08 | Geigy Ag J R | New sulphamoyl benzamides and processes for the production thereof |
| US3072656A (en) * | 1960-01-22 | 1963-01-08 | Ciba Geigy Corp | 2-cycloaliphatic-6-sulfamyl-7-halo(or trihalomethyl)-1, 2, 3, 4-tetrahydro-4-quinazolones |
-
1964
- 1964-05-29 FR FR976292A patent/FR1403935A/fr not_active Expired
- 1964-06-01 GB GB22608/64A patent/GB1033268A/en not_active Expired
- 1964-06-02 US US372086A patent/US3318882A/en not_active Expired - Lifetime
- 1964-06-03 DE DE19641445629D patent/DE1445629B1/de active Pending
- 1964-06-03 ES ES300569A patent/ES300569A1/es not_active Expired
- 1964-06-04 AT AT900665A patent/AT261593B/de active
- 1964-06-04 BE BE648829A patent/BE648829A/xx unknown
- 1964-06-04 AT AT482264A patent/AT254176B/de active
- 1964-06-04 SE SE6822/64A patent/SE311644B/xx unknown
- 1964-06-04 NL NL646406335A patent/NL140236B/xx unknown
- 1964-06-04 SE SE8159/66A patent/SE311517B/xx unknown
- 1964-06-04 AT AT900565A patent/AT254221B/de active
- 1964-06-05 BR BR159789/64A patent/BR6459789D0/pt unknown
- 1964-08-21 FR FR985807A patent/FR3528M/fr not_active Expired
- 1964-08-21 FR FR985808A patent/FR3529M/fr not_active Expired
-
1966
- 1966-06-15 SE SE8158/66A patent/SE311646B/xx unknown
-
1969
- 1969-12-31 MY MY1969400A patent/MY6900400A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL140236B (nl) | 1973-11-15 |
| GB1033268A (en) | 1966-06-22 |
| DE1445629B1 (de) | 1971-08-12 |
| ES300569A1 (es) | 1964-11-16 |
| US3318882A (en) | 1967-05-09 |
| BE648829A (xx) | 1964-12-04 |
| AT261593B (de) | 1968-05-10 |
| AT254221B (de) | 1967-05-10 |
| SE311517B (xx) | 1969-06-16 |
| NL6406335A (xx) | 1964-12-07 |
| FR3528M (fr) | 1965-09-06 |
| SE311644B (xx) | 1969-06-23 |
| MY6900400A (en) | 1969-12-31 |
| FR3529M (fr) | 1965-09-06 |
| AT254176B (de) | 1967-05-10 |
| BR6459789D0 (pt) | 1973-07-17 |
| FR1403935A (fr) | 1965-06-25 |
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