SE7905865L - Nya acetylenderivat av androsten-4-en, sett for framstellning och anvendning derav sasom lekemedel samt farmaceutiska kompositioner innehallande dessa foreningar - Google Patents
Nya acetylenderivat av androsten-4-en, sett for framstellning och anvendning derav sasom lekemedel samt farmaceutiska kompositioner innehallande dessa foreningarInfo
- Publication number
- SE7905865L SE7905865L SE7905865A SE7905865A SE7905865L SE 7905865 L SE7905865 L SE 7905865L SE 7905865 A SE7905865 A SE 7905865A SE 7905865 A SE7905865 A SE 7905865A SE 7905865 L SE7905865 L SE 7905865L
- Authority
- SE
- Sweden
- Prior art keywords
- carbon atoms
- hydrogen
- preparation
- androsten
- compounds
- Prior art date
Links
- 150000000475 acetylene derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 5
- 229910052731 fluorine Inorganic materials 0.000 abstract 3
- 239000011737 fluorine Substances 0.000 abstract 3
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- IATKKATWPOVYCC-VMXHOPILSA-N (8s,9s,10r,13s,14s)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1h-cyclopenta[a]phenanthrene Chemical class C1CC2=CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 IATKKATWPOVYCC-VMXHOPILSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7823851A FR2433536A1 (fr) | 1978-08-16 | 1978-08-16 | Nouveaux derives de l'androst 4-ene, leur procede de preparation et leur application comme medicament |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7905865L true SE7905865L (sv) | 1980-02-17 |
| SE435186B SE435186B (sv) | 1984-09-10 |
Family
ID=9211827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7905865A SE435186B (sv) | 1978-08-16 | 1979-07-04 | Nya acetylenderivat av androst-4-en samt en farmaceutisk komposition |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4232015A (sv) |
| JP (1) | JPS5528982A (sv) |
| AT (1) | AT368520B (sv) |
| AU (1) | AU524232B2 (sv) |
| BE (1) | BE878256A (sv) |
| CH (1) | CH641814A5 (sv) |
| DE (1) | DE2933258A1 (sv) |
| FR (1) | FR2433536A1 (sv) |
| GB (1) | GB2029833B (sv) |
| HU (1) | HU180520B (sv) |
| IE (1) | IE48931B1 (sv) |
| IT (1) | IT1164040B (sv) |
| NL (1) | NL7906214A (sv) |
| PT (1) | PT70060A (sv) |
| SE (1) | SE435186B (sv) |
| ZA (1) | ZA793967B (sv) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4424218A (en) | 1979-08-17 | 1984-01-03 | Roussel Uclaf | Novel 3 α-amino steroids |
| FR2468617A1 (fr) * | 1979-10-26 | 1981-05-08 | Roussel Uclaf | Nouveaux derives acetyleniques chlores de l'androst-4-ene leur procede de preparation, et leur application a titre de medicament et les compositions pharmaceutiques les renfermant |
| US4383947A (en) * | 1981-07-24 | 1983-05-17 | The Upjohn Company | Introduction of a fluorine atom |
| US4488995A (en) * | 1984-02-06 | 1984-12-18 | E. R. Squibb & Sons, Inc. | Androstene-17β-alkylthiomethyl ethers |
| US6740646B2 (en) * | 2002-01-16 | 2004-05-25 | Biotest Laboratories, Llc | Bioavailable prodrugs of androgenic steroids and related method |
| JP4636847B2 (ja) * | 2004-10-13 | 2011-02-23 | 株式会社ロッテ | 全粒粉からなる小麦粉の加工方法及びその加工方法により得られた加工小麦粉並びにその加工小麦粉を使用した食品 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2740798A (en) * | 1953-05-25 | 1956-04-03 | Searle & Co | 11 beta-hydroxy-17-ethynyl testosterone and esters thereof |
| US3010957A (en) * | 1958-11-26 | 1961-11-28 | Schering Corp | Ethinyl androstadienes |
| FR1349113A (fr) * | 1959-01-28 | 1964-01-17 | Upjohn Co | Procédé de fabrication de 6-fluoro-11 oxygéné-17-bêta-hydroxy-17 alpha-alkynyl inférieur-4-androstène-3-ones et leurs dérivés acylés |
| GB1081494A (en) * | 1965-09-14 | 1967-08-31 | British Drug Houses Ltd | 17ª-(alka-1',3'-diynyl)-steroids |
| US3793308A (en) * | 1972-11-08 | 1974-02-19 | Upjohn Co | 4-spiro(cyclopropyl)androstenes and process for their production |
| SE7801152L (sv) * | 1977-02-22 | 1978-08-23 | Roussel Uclaf | Sett att framstella 17alfa-acetylen-derivat av androst-4-en |
-
1978
- 1978-08-16 FR FR7823851A patent/FR2433536A1/fr active Granted
-
1979
- 1979-07-04 SE SE7905865A patent/SE435186B/sv not_active IP Right Cessation
- 1979-07-24 HU HU79RO1032A patent/HU180520B/hu not_active IP Right Cessation
- 1979-08-02 ZA ZA00793967A patent/ZA793967B/xx unknown
- 1979-08-06 US US06/063,939 patent/US4232015A/en not_active Expired - Lifetime
- 1979-08-13 PT PT70060A patent/PT70060A/pt unknown
- 1979-08-14 AT AT0553479A patent/AT368520B/de not_active IP Right Cessation
- 1979-08-14 BE BE0/196747A patent/BE878256A/fr not_active IP Right Cessation
- 1979-08-14 IT IT50049/79A patent/IT1164040B/it active
- 1979-08-15 AU AU49958/79A patent/AU524232B2/en not_active Ceased
- 1979-08-15 CH CH749079A patent/CH641814A5/fr not_active IP Right Cessation
- 1979-08-15 NL NL7906214A patent/NL7906214A/nl not_active Application Discontinuation
- 1979-08-16 IE IE1578/79A patent/IE48931B1/en not_active IP Right Cessation
- 1979-08-16 GB GB7928508A patent/GB2029833B/en not_active Expired
- 1979-08-16 DE DE19792933258 patent/DE2933258A1/de active Granted
- 1979-08-16 JP JP10363879A patent/JPS5528982A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS636559B2 (sv) | 1988-02-10 |
| AU524232B2 (en) | 1982-09-09 |
| AU4995879A (en) | 1980-03-06 |
| IE48931B1 (en) | 1985-06-26 |
| FR2433536B1 (sv) | 1981-07-24 |
| GB2029833B (en) | 1983-04-27 |
| US4232015A (en) | 1980-11-04 |
| HU180520B (en) | 1983-03-28 |
| ZA793967B (en) | 1980-07-30 |
| IT7950049A0 (it) | 1979-08-14 |
| IT1164040B (it) | 1987-04-08 |
| JPS5528982A (en) | 1980-02-29 |
| FR2433536A1 (fr) | 1980-03-14 |
| AT368520B (de) | 1982-10-25 |
| NL7906214A (nl) | 1980-02-19 |
| DE2933258A1 (de) | 1980-02-28 |
| SE435186B (sv) | 1984-09-10 |
| PT70060A (fr) | 1979-09-01 |
| ATA553479A (de) | 1982-02-15 |
| IE791578L (en) | 1980-02-16 |
| BE878256A (fr) | 1980-02-14 |
| CH641814A5 (fr) | 1984-03-15 |
| DE2933258C2 (sv) | 1990-10-25 |
| GB2029833A (en) | 1980-03-26 |
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