GB938306A - New quinazolone compounds - Google Patents
New quinazolone compoundsInfo
- Publication number
- GB938306A GB938306A GB34098/61A GB3409861A GB938306A GB 938306 A GB938306 A GB 938306A GB 34098/61 A GB34098/61 A GB 34098/61A GB 3409861 A GB3409861 A GB 3409861A GB 938306 A GB938306 A GB 938306A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- nitro
- prepared
- compounds
- quinazolone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention comprises quinazolone derivatives (soporific and narcotic agents) of the general formula <FORM:0938306/IV(a)/1> (wherein R is a hydrogen atom or a C1-4 alkyl radical, X is an acylamino radical wherein the acyl residue is derived from carbonic acid, thiocarbonic acid or a carboxylic acid, R1 is a C1-4 alkyl radical and n is 1 or 2), and their preparation by acylating a compound of the general formula <FORM:0938306/IV(a)/2> to convert the or each amino group into a group X. The starting materials may be prepared by reducing the corresponding nitro compounds. 3- Carbethoxyamino- 6- nitroquinazolone-(4) is prepared by condensing 5-nitroanthranilic acid hydrazide-o -carboxylic acid ethyl ester with formic acid. 2- Methyl- 3- carbethoxyamino- 7- nitro-quinazolone-(4) is prepared by boiling 4-nitro-anthranilic acid with acetic anhydride, and heating the resulting anhydro-(N-acetyl-4-nitroanthranilic acid) with hydrazine-monocarboxylic acid ethyl ester. The 6-nitro- and 6,8-dinitro-compounds are prepared similarly. Specification 896,846 is referred to.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB34098/61A GB938306A (en) | 1961-09-22 | 1961-09-22 | New quinazolone compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB34098/61A GB938306A (en) | 1961-09-22 | 1961-09-22 | New quinazolone compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB938306A true GB938306A (en) | 1963-10-02 |
Family
ID=10361351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB34098/61A Expired GB938306A (en) | 1961-09-22 | 1961-09-22 | New quinazolone compounds |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB938306A (en) |
-
1961
- 1961-09-22 GB GB34098/61A patent/GB938306A/en not_active Expired
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