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RU95113454A - Катехольные диэфиры как селективные ингибиторы фдэiv, фармацевтическая композиция, способы лечения - Google Patents

Катехольные диэфиры как селективные ингибиторы фдэiv, фармацевтическая композиция, способы лечения

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Publication number
RU95113454A
RU95113454A RU95113454/04A RU95113454A RU95113454A RU 95113454 A RU95113454 A RU 95113454A RU 95113454/04 A RU95113454/04 A RU 95113454/04A RU 95113454 A RU95113454 A RU 95113454A RU 95113454 A RU95113454 A RU 95113454A
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RU
Russia
Prior art keywords
phosphodiesterase
treatment
fde
methods
pharmaceutical composition
Prior art date
Application number
RU95113454/04A
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English (en)
Inventor
Дж.Дуплантир Аллен
Us]
Ф.Эгглер Джеймс
Марфат Антони
Масамьюн Хироко
Original Assignee
Пфайзер Инк. (US)
Пфайзер Инк.
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Application filed by Пфайзер Инк. (US), Пфайзер Инк. filed Critical Пфайзер Инк. (US)
Publication of RU95113454A publication Critical patent/RU95113454A/ru

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
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    • C07C2603/64—Ring systems containing bridged rings containing three rings containing at least one ring with less than six members containing three- or four-membered rings having a tricyclo[2.2.1.0(2,6)]heptstructure

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Abstract

Предложены 4 - замещенные катехольные диэфиры, являющиеся эффективными ингибиторами фосфодиэстеразы типа 1У и способные излечивать такие болезни, как СПИД, астму, бронхит, хронические заболевания дыхательных путей, псориаз, дерматит и другие воспалительные заболевания. Также предлагаются фармацевтические композиции, составляемые на основе этих соединений.

Claims (1)

  1. Предложены 4 - замещенные катехольные диэфиры, являющиеся эффективными ингибиторами фосфодиэстеразы типа 1У и способные излечивать такие болезни, как СПИД, астму, бронхит, хронические заболевания дыхательных путей, псориаз, дерматит и другие воспалительные заболевания. Также предлагаются фармацевтические композиции, составляемые на основе этих соединений.
RU95113454/04A 1992-12-02 1993-10-29 Катехольные диэфиры как селективные ингибиторы фдэiv, фармацевтическая композиция, способы лечения RU95113454A (ru)

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CA2150812C (en) 2002-12-24
BR9307570A (pt) 1999-05-25
CN1094028A (zh) 1994-10-26
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AU673569B2 (en) 1996-11-14
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JPH08501318A (ja) 1996-02-13
JP3100984B2 (ja) 2000-10-23
CA2150812A1 (en) 1994-06-09
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IL107758A0 (en) 1994-02-27
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