RU95104936A - Препарат для инъекций и набор для инъекций, содержащие омепразол и его аналоги - Google Patents
Препарат для инъекций и набор для инъекций, содержащие омепразол и его аналогиInfo
- Publication number
- RU95104936A RU95104936A RU95104936/14A RU95104936A RU95104936A RU 95104936 A RU95104936 A RU 95104936A RU 95104936/14 A RU95104936/14 A RU 95104936/14A RU 95104936 A RU95104936 A RU 95104936A RU 95104936 A RU95104936 A RU 95104936A
- Authority
- RU
- Russia
- Prior art keywords
- injection
- salt
- aqueous solvent
- methylsulfinyl
- pyridyl
- Prior art date
Links
Claims (5)
1. Препарат для инъекций, содержащий 2-[(2-пиридил) метилсульфинил]бензимидазольное соединение или его соль, обладающие противоязвенной активностью, отличающийся тем, что содержит водный растворитель без добавок неводного растворителя, причем pH препарата для инъекций не менее 9,5 и не более 11,5.
2. Препарат по п.1, отличающийся тем, что содержит растворенный продукт лиофилизированного щелочного водного раствора 2-[(2-пиридил) метилсульфинил] бензимидазольного соединения или его соли, обладающих противоязвенной активностью, в водном растворителе без добавления неводного растворителя.
3. Препарат для инъекций по п.1 или 2, отличающийся тем, что 2-[(2-пиридил)метилсульфинил] бензимидазольным соединением или его солью является натриевая соль омепразола.
4. Набор для инъекций, содержащий компоненты (a) и (b), где (a) и (b) подбирают таким образом, чтобы pH после растворения (a) в (b) был не менее 9,5 и не более 11,5, где (a) - лиофилизированный продукт щелочного водного раствора 2-[(2-пиридил) метилсульфинил]бензимидазольного соединения или его соли, обладающих противоязвенной активностью, (b) - водный растворитель без добавления неводного растворителя.
5. Набор для инъекций по п.4, отличающийся тем, что 2-[(2-пиридил) метилсульфинил] бензимидазольным соединением или его солью является натриевая соль омепразола.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20120392 | 1992-07-28 | ||
| JP4/201203 | 1992-07-28 | ||
| PCT/JP1993/000998 WO1994002141A1 (en) | 1992-07-28 | 1993-07-15 | Injection and injection kit containing omeprazole and its analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU95104936A true RU95104936A (ru) | 1997-11-27 |
| RU2126252C1 RU2126252C1 (ru) | 1999-02-20 |
Family
ID=16437061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU95104936A RU2126252C1 (ru) | 1992-07-28 | 1993-07-15 | Препарат для инъекций и набор для инъекций, содержащие омепразол и его аналоги |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5589491A (ru) |
| EP (1) | EP0652751B1 (ru) |
| KR (1) | KR100258423B1 (ru) |
| AT (1) | ATE144421T1 (ru) |
| AU (1) | AU674015B2 (ru) |
| CA (1) | CA2140347C (ru) |
| CZ (1) | CZ284249B6 (ru) |
| DE (1) | DE69305642T2 (ru) |
| DK (1) | DK0652751T3 (ru) |
| ES (1) | ES2093445T3 (ru) |
| FI (1) | FI113338B (ru) |
| GR (1) | GR3021937T3 (ru) |
| HK (1) | HK52397A (ru) |
| HU (1) | HU226778B1 (ru) |
| NO (1) | NO304098B1 (ru) |
| NZ (1) | NZ254237A (ru) |
| RU (1) | RU2126252C1 (ru) |
| SG (1) | SG52479A1 (ru) |
| SK (1) | SK279554B6 (ru) |
| WO (1) | WO1994002141A1 (ru) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4324014C2 (de) * | 1993-07-17 | 1995-06-08 | Byk Gulden Lomberg Chem Fab | Verfahren zur Herstellung einer in Wasser rekonstituierbaren Zubereitung |
| US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
| US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
| US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
| US6096340A (en) * | 1997-11-14 | 2000-08-01 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6174548B1 (en) | 1998-08-28 | 2001-01-16 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6733778B1 (en) | 1999-08-27 | 2004-05-11 | Andrx Pharmaceuticals, Inc. | Omeprazole formulation |
| US6262085B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| US6316020B1 (en) * | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
| US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
| US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
| US6312712B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Method of improving bioavailability |
| US6262086B1 (en) | 1999-08-26 | 2001-07-17 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6326384B1 (en) | 1999-08-26 | 2001-12-04 | Robert R. Whittle | Dry blend pharmaceutical unit dosage form |
| US6312723B1 (en) | 1999-08-26 | 2001-11-06 | Robert R. Whittle | Pharmaceutical unit dosage form |
| US6369087B1 (en) | 1999-08-26 | 2002-04-09 | Robert R. Whittle | Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same |
| SE9903831D0 (sv) * | 1999-10-22 | 1999-10-22 | Astra Ab | Formulation of substituted benzimidazoles |
| US7396841B2 (en) | 2000-08-18 | 2008-07-08 | Takeda Pharmaceutical Company Limited | Injections |
| AU2001296908A1 (en) * | 2000-09-29 | 2002-04-08 | Geneva Pharmaceuticals, Inc. | Proton pump inhibitor formulation |
| MY137726A (en) | 2000-11-22 | 2009-03-31 | Nycomed Gmbh | Freeze-dried pantoprazole preparation and pantoprazole injection |
| US20020192299A1 (en) * | 2000-12-28 | 2002-12-19 | Rajneesh Taneja | Pharmaceutical compositions of a non-enteric coated proton pump inhibitor with a carbonate salt and bicarbonate salt combination |
| KR100467100B1 (ko) * | 2002-03-20 | 2005-01-24 | 일양약품주식회사 | 2-[(4-메톡시-3-메틸)-2-피리디닐]메틸설피닐-5-(1Ｈ-피롤-1-릴)-1Ｈ-벤즈이미다졸 또는 이의 Ｎа염을 함유하는주사제의 제조방법 |
| US20030228363A1 (en) * | 2002-06-07 | 2003-12-11 | Patel Mahendra R. | Stabilized pharmaceutical compositons containing benzimidazole compounds |
| US20040082618A1 (en) * | 2002-07-03 | 2004-04-29 | Rajneesh Taneja | Liquid dosage forms of acid labile drugs |
| US20040006109A1 (en) * | 2002-07-03 | 2004-01-08 | Rajneesh Taneja | Liquid dosage forms of non-enterically coated acid-labile drugs |
| US20040081671A1 (en) * | 2002-07-03 | 2004-04-29 | Rajneesh Taneja | Liquid dosage forms of non-enterically coated acid-labile drugs |
| US20070243251A1 (en) * | 2002-12-20 | 2007-10-18 | Rajneesh Taneja | Dosage Forms Containing A PPI, NSAID, and Buffer |
| US20040121004A1 (en) * | 2002-12-20 | 2004-06-24 | Rajneesh Taneja | Dosage forms containing a PPI, NSAID, and buffer |
| US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| AR045258A1 (es) * | 2003-08-21 | 2005-10-19 | Altana Pharma Ag | Un producto farmaceutico para inyeccion |
| EP1713476B1 (en) | 2003-11-05 | 2010-05-05 | Lyka Labs Limited | Process for the preparation of benzimidazoles |
| US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
| US20070026071A1 (en) * | 2005-07-28 | 2007-02-01 | Qpharma, Llc | Magnesium salt proton pump inhibitor dosage forms |
| WO2007091276A2 (en) * | 2006-02-10 | 2007-08-16 | Rajasthan Antibiotic Limited | Novel crystal form of omeprazol sodium |
| CN104288175A (zh) * | 2014-09-17 | 2015-01-21 | 大生祥(武汉）中医投资管理有限公司 | 一种新的苯并咪唑类异构体制剂及其制备方法 |
| PT3386507T (pt) * | 2015-12-08 | 2023-09-11 | Luoda Pharma Ltd | Métodos e composições para tratar úlceras gástricas |
| CN105919953A (zh) * | 2016-06-27 | 2016-09-07 | 峨眉山通惠制药有限公司 | 一种注射用奥美拉唑钠组合物及其制作工艺 |
| GB2585628A (en) * | 2019-05-08 | 2021-01-20 | Alkaloid Ad | Pharmaceutical formulation |
| CN112807282A (zh) * | 2021-01-13 | 2021-05-18 | 海南葫芦娃药业集团股份有限公司 | 一种奥美拉唑钠冻干粉针剂及其制备方法 |
| WO2024075017A1 (en) | 2022-10-04 | 2024-04-11 | Zabirnyk Arsenii | Inhibition of aortic valve calcification |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE416649B (sv) * | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
| SE7804231L (sv) * | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
| US4359465A (en) * | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
| US4472409A (en) * | 1981-11-05 | 1984-09-18 | Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung | 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects |
| SE8300736D0 (sv) * | 1983-02-11 | 1983-02-11 | Haessle Ab | Novel pharmacologically active compounds |
| SE8301182D0 (sv) * | 1983-03-04 | 1983-03-04 | Haessle Ab | Novel compounds |
| JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| DK399389A (da) * | 1988-08-18 | 1990-02-19 | Takeda Chemical Industries Ltd | Injicerbare oploesninger |
| DE69014141T2 (de) * | 1989-02-10 | 1995-05-24 | Takeda Chemical Industries Ltd | Verwendung von Benzimidazol-Derivaten als antibakterielle Mittel. |
| US5049674A (en) * | 1989-12-20 | 1991-09-17 | Aktiebolaget Hassle | Therapeutically active fluoro substituted benzimidazoles |
-
1993
- 1993-07-15 DE DE69305642T patent/DE69305642T2/de not_active Expired - Fee Related
- 1993-07-15 KR KR1019950700327A patent/KR100258423B1/ko not_active Expired - Fee Related
- 1993-07-15 SG SG1996005084A patent/SG52479A1/en unknown
- 1993-07-15 HU HU9500245A patent/HU226778B1/hu not_active IP Right Cessation
- 1993-07-15 NZ NZ254237A patent/NZ254237A/en not_active IP Right Cessation
- 1993-07-15 SK SK100-95A patent/SK279554B6/sk not_active IP Right Cessation
- 1993-07-15 ES ES93916182T patent/ES2093445T3/es not_active Expired - Lifetime
- 1993-07-15 CZ CZ95217A patent/CZ284249B6/cs not_active IP Right Cessation
- 1993-07-15 CA CA002140347A patent/CA2140347C/en not_active Expired - Lifetime
- 1993-07-15 EP EP93916182A patent/EP0652751B1/en not_active Expired - Lifetime
- 1993-07-15 AT AT93916182T patent/ATE144421T1/de not_active IP Right Cessation
- 1993-07-15 WO PCT/JP1993/000998 patent/WO1994002141A1/en active IP Right Grant
- 1993-07-15 US US08/373,245 patent/US5589491A/en not_active Expired - Lifetime
- 1993-07-15 RU RU95104936A patent/RU2126252C1/ru not_active IP Right Cessation
- 1993-07-15 AU AU45838/93A patent/AU674015B2/en not_active Ceased
- 1993-07-15 DK DK93916182.4T patent/DK0652751T3/da active
-
1995
- 1995-01-17 NO NO950178A patent/NO304098B1/no not_active IP Right Cessation
- 1995-01-27 FI FI950379A patent/FI113338B/fi active
-
1996
- 1996-12-06 GR GR960403351T patent/GR3021937T3/el unknown
-
1997
- 1997-04-24 HK HK52397A patent/HK52397A/xx not_active IP Right Cessation
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